Sort by
Items per page

Send to

Choose Destination

Search results

Items: 18


Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors.

Gonzalez-Duque S, Azoury ME, Colli ML, Afonso G, Turatsinze JV, Nigi L, Lalanne AI, Sebastiani G, Carré A, Pinto S, Culina S, Corcos N, Bugliani M, Marchetti P, Armanet M, Diedisheim M, Kyewski B, Steinmetz LM, Buus S, You S, Dubois-Laforgue D, Larger E, Beressi JP, Bruno G, Dotta F, Scharfmann R, Eizirik DL, Verdier Y, Vinh J, Mallone R.

Cell Metab. 2018 Dec 4;28(6):946-960.e6. doi: 10.1016/j.cmet.2018.07.007. Epub 2018 Aug 2.


Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.

Culina S, Lalanne AI, Afonso G, Cerosaletti K, Pinto S, Sebastiani G, Kuranda K, Nigi L, Eugster A, Østerbye T, Maugein A, McLaren JE, Ladell K, Larger E, Beressi JP, Lissina A, Appay V, Davidson HW, Buus S, Price DA, Kuhn M, Bonifacio E, Battaglia M, Caillat-Zucman S, Dotta F, Scharfmann R, Kyewski B, Mallone R; ImMaDiab Study Group.

Sci Immunol. 2018 Feb 2;3(20). pii: eaao4013. doi: 10.1126/sciimmunol.aao4013.


Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.

James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee.

Diabetologia. 2018 Mar;61(3):658-670. doi: 10.1007/s00125-017-4508-8. Epub 2017 Dec 1.


Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques.

Todorova B, Adam L, Culina S, Boisgard R, Martinon F, Cosma A, Ustav M, Kortulewski T, Le Grand R, Chapon C.

Sci Rep. 2017 Jun 23;7(1):4122. doi: 10.1038/s41598-017-04547-2.


Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes.

Culina S, Gupta N, Boisgard R, Afonso G, Gagnerault MC, Dimitrov J, Østerbye T, Justesen S, Luce S, Attias M, Kyewski B, Buus S, Wong FS, Lacroix-Desmazes S, Mallone R.

Diabetes. 2015 Oct;64(10):3532-42. doi: 10.2337/db15-0024. Epub 2015 Apr 27.


Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance.

Gupta N, Culina S, Meslier Y, Dimitrov J, Arnoult C, Delignat S, Gangadharan B, Lecerf M, Justesen S, Gouilleux-Gruart V, Salomon BL, Scott DW, Kaveri SV, Mallone R, Lacroix-Desmazes S.

Sci Transl Med. 2015 Feb 18;7(275):275ra21. doi: 10.1126/scitranslmed.aaa1957.


Of bugs and men: antigen-fortified Lactoccoccus lactis for type 1 diabetes immunotherapy.

Mallone R, Culina S.

Diabetes. 2014 Aug;63(8):2603-5. doi: 10.2337/db14-0587. No abstract available.


Endoplasmic reticulum targeting alters regulation of expression and antigen presentation of proinsulin.

Hsu HT, Janßen L, Lawand M, Kim J, Perez-Arroyo A, Culina S, Gdoura A, Burgevin A, Cumenal D, Fourneau Y, Moser A, Kratzer R, Wong FS, Springer S, van Endert P.

J Immunol. 2014 Jun 1;192(11):4957-66. doi: 10.4049/jimmunol.1300631. Epub 2014 Apr 28.


No major role for insulin-degrading enzyme in antigen presentation by MHC molecules.

Culina S, Mauvais FX, Hsu HT, Burgevin A, Guénette S, Moser A, van Endert P.

PLoS One. 2014 Feb 7;9(2):e88365. doi: 10.1371/journal.pone.0088365. eCollection 2014.


Deletion of the fission yeast homologue of human insulinase reveals a TORC1-dependent pathway mediating resistance to proteotoxic stress.

Beuzelin C, Evnouchidou I, Rigolet P, Cauvet-Burgevin A, Girard PM, Dardalhon D, Culina S, Gdoura A, van Endert P, Francesconi S.

PLoS One. 2013 Jun 24;8(6):e67705. doi: 10.1371/journal.pone.0067705. Print 2013.


Insulin and type 1 diabetes: immune connections.

Culina S, Brezar V, Mallone R.

Eur J Endocrinol. 2013 Jan 17;168(2):R19-31. doi: 10.1530/EJE-12-0693. Print 2013 Feb. Review.


Immune biomarkers in immunotherapeutic trials for type 1 diabetes: cui prodest?

Culina S, Mallone R.

Diabetes Metab. 2012 Nov;38(5):379-85. doi: 10.1016/j.diabet.2012.05.005. Epub 2012 Jul 31. Review.


Short-term subcutaneous insulin treatment delays but does not prevent diabetes in NOD mice.

Brezar V, Culina S, Gagnerault MC, Mallone R.

Eur J Immunol. 2012 Jun;42(6):1553-61. doi: 10.1002/eji.201242394.


T cells recognizing a peptide contaminant undetectable by mass spectrometry.

Brezar V, Culina S, Østerbye T, Guillonneau F, Chiappetta G, Verdier Y, Vinh J, Wong FS, Buus S, Mallone R.

PLoS One. 2011;6(12):e28866. doi: 10.1371/journal.pone.0028866. Epub 2011 Dec 14.


Pathogenic and regulatory T cells in type 1 diabetes: losing self-control, restoring it, and how to take the temperature.

Culina S, Mallone R.

Curr Diab Rep. 2011 Oct;11(5):426-33. doi: 10.1007/s11892-011-0209-8. Review.


Antigen-based immune therapeutics for type 1 diabetes: magic bullets or ordinary blanks?

Culina S, Boitard C, Mallone R.

Clin Dev Immunol. 2011;2011:286248. doi: 10.1155/2011/286248. Epub 2011 May 14.


Persistent immune responses induced by a human immunodeficiency virus DNA vaccine delivered in association with electroporation in the skin of nonhuman primates.

Martinon F, Kaldma K, Sikut R, Culina S, Romain G, Tuomela M, Adojaan M, Männik A, Toots U, Kivisild T, Morin J, Brochard P, Delache B, Tripiciano A, Ensoli F, Stanescu I, Le Grand R, Ustav M.

Hum Gene Ther. 2009 Nov;20(11):1291-307. doi: 10.1089/hum.2009.044.


Calreticulin promotes folding of functional human leukocyte antigen class I molecules in vitro.

Culina S, Lauvau G, Gubler B, van Endert PM.

J Biol Chem. 2004 Dec 24;279(52):54210-5. Epub 2004 Oct 19.

Supplemental Content

Loading ...
Support Center