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Items: 45


Pediatric liver transplantation.

Cuenca AG, Kim HB, Vakili K.

Semin Pediatr Surg. 2017 Aug;26(4):217-223. doi: 10.1053/j.sempedsurg.2017.07.014. Epub 2017 Jul 26. Review.


Clostridium difficile Infections after Blunt Trauma: A Different Patient Population?

Vanzant EL, Ozrazgat-Baslanti T, Liu H, Malik S, Davis R, Lanz J, Miggins MV, Gentile LF, Cuenca A, Cuenca AG, Lottenberg L, Moore FA, Ang DN, Bihorac A, Efron PA.

Surg Infect (Larchmt). 2015 Aug;16(4):421-7. doi: 10.1089/sur.2013.141. Epub 2015 Jun 2.


Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit.

Szpila BE, Ozrazgat-Baslanti T, Zhang J, Lanz J, Davis R, Rebel A, Vanzant E, Gentile LF, Cuenca AG, Ang DN, Liu H, Lottenberg L, Marker P, Zumberg M, Bihorac A, Moore FA, Brakenridge S, Efron PA.

PLoS One. 2015 May 26;10(5):e0126895. doi: 10.1371/journal.pone.0126895. eCollection 2015.


Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation.

Gentile LF, Cuenca AL, Cuenca AG, Nacionales DC, Ungaro R, Efron PA, Moldawer LL, Larson SD.

Immunology. 2015 Jun;145(2):300-11. doi: 10.1111/imm.12450.


TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis.

Cuenca AG, Joiner DN, Gentile LF, Cuenca AL, Wynn JL, Kelly-Scumpia KM, Scumpia PO, Behrns KE, Efron PA, Nacionales D, Lui C, Wallet SM, Reeves WH, Mathews CE, Moldawer LL.

J Immunol. 2015 Feb 1;194(3):1169-77. doi: 10.4049/jimmunol.1302676. Epub 2014 Dec 29.


Delayed emergency myelopoiesis following polymicrobial sepsis in neonates.

Cuenca AG, Cuenca AL, Gentile LF, Efron PA, Islam S, Moldawer LL, Kays DW, Larson SD.

Innate Immun. 2015 May;21(4):386-91. doi: 10.1177/1753425914542445. Epub 2014 Aug 7.


Omental flaps for coverage of sacral or gluteal defects: a useful and potentially underused tool.

Raza A, Cuenca AG, Tan S, Singhal D.

Am Surg. 2014 Jul;80(7):e202-4. No abstract available.


Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia.

Cuenca AG, Cuenca AL, Winfield RD, Joiner DN, Gentile L, Delano MJ, Kelly-Scumpia KM, Scumpia PO, Matheny MK, Scarpace PJ, Vila L, Efron PA, LaFace DM, Moldawer LL.

J Immunol. 2014 Jun 15;192(12):6111-9. doi: 10.4049/jimmunol.1302895. Epub 2014 May 14.


Host responses to sepsis vary in different low-lethality murine models.

Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Szpila BE, Cuenca AG, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA.

PLoS One. 2014 May 1;9(5):e94404. doi: 10.1371/journal.pone.0094404. eCollection 2014.


Protective immunity and defects in the neonatal and elderly immune response to sepsis.

Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Szpila BE, Larson S, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA.

J Immunol. 2014 Apr 1;192(7):3156-65. doi: 10.4049/jimmunol.1301726. Epub 2014 Mar 3.


A better understanding of why murine models of trauma do not recapitulate the human syndrome.

Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA.

Crit Care Med. 2014 Jun;42(6):1406-13. doi: 10.1097/CCM.0000000000000222.


Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma.

Vanzant EL, Lopez CM, Ozrazgat-Baslanti T, Ungaro R, Davis R, Cuenca AG, Gentile LF, Nacionales DC, Cuenca AL, Bihorac A, Leeuwenburgh C, Lanz J, Baker HV, McKinley B, Moldawer LL, Moore FA, Efron PA.

J Trauma Acute Care Surg. 2014 Jan;76(1):21-9; discussion 29-30. doi: 10.1097/TA.0b013e3182ab1ab5.


Aged mice are unable to mount an effective myeloid response to sepsis.

Nacionales DC, Gentile LF, Vanzant E, Lopez MC, Cuenca A, Cuenca AG, Ungaro R, Li Y, Baslanti TO, Bihorac A, Moore FA, Baker HV, Leeuwenburgh C, Moldawer LL, Efron PA.

J Immunol. 2014 Jan 15;192(2):612-22. doi: 10.4049/jimmunol.1302109. Epub 2013 Dec 13.


Is there value in plasma cytokine measurements in patients with severe trauma and sepsis?

Gentile LF, Cuenca AG, Vanzant EL, Efron PA, McKinley B, Moore F, Moldawer LL.

Methods. 2013 May 15;61(1):3-9. doi: 10.1016/j.ymeth.2013.04.024. Epub 2013 May 11. Review.


Acute kidney injury is associated with early cytokine changes after trauma.

Bihorac A, Baslanti TO, Cuenca AG, Hobson CE, Ang D, Efron PA, Maier RV, Moore FA, Moldawer LL.

J Trauma Acute Care Surg. 2013 Apr;74(4):1005-13. doi: 10.1097/TA.0b013e31828586ec.


Genomic responses in mouse models poorly mimic human inflammatory diseases.

Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12. doi: 10.1073/pnas.1222878110. Epub 2013 Feb 11.


Identification and description of a novel murine model for polytrauma and shock.

Gentile LF, Nacionales DC, Cuenca AG, Armbruster M, Ungaro RF, Abouhamze AS, Lopez C, Baker HV, Moore FA, Ang DN, Efron PA.

Crit Care Med. 2013 Apr;41(4):1075-85. doi: 10.1097/CCM.0b013e318275d1f9.


Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients.

Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Baslanti TO, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL; Inflammation and Host Response to Injury Collaborative Research Program.

Crit Care Med. 2013 May;41(5):1175-85. doi: 10.1097/CCM.0b013e318277131c.


Role of innate immunity in neonatal infection.

Cuenca AG, Wynn JL, Moldawer LL, Levy O.

Am J Perinatol. 2013 Feb;30(2):105-12. doi: 10.1055/s-0032-1333412. Epub 2013 Jan 7. Review.


A genomic analysis of Clostridium difficile infections in blunt trauma patients.

Efron PA, Liu H, Lottenberg L, Cuenca AG, Gentile LF, Miggins MV, Bihorac A, Baker HV, Moore FA, Moldawer LL, Ang DN.

J Trauma Acute Care Surg. 2013 Jan;74(1):334-8. doi: 10.1097/TA.0b013e3182789426.


The acute immunological response to blood transfusion is influenced by polymicrobial sepsis.

Nacionales DC, Cuenca AG, Ungaro R, Gentile LF, Joiner D, Satoh M, Lomas-Neira J, Ayala A, Bihorac A, Delano MJ, Ang DN, Efron PA.

Shock. 2012 Dec;38(6):598-606. doi: 10.1097/SHK.0b013e318273621a.


Pediatric pancreatic trauma: trending toward nonoperative management?

Cuenca AG, Islam S.

Am Surg. 2012 Nov;78(11):1204-10.


Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care.

Gentile LF, Cuenca AG, Efron PA, Ang D, Bihorac A, McKinley BA, Moldawer LL, Moore FA.

J Trauma Acute Care Surg. 2012 Jun;72(6):1491-501. doi: 10.1097/TA.0b013e318256e000. Review.


Myeloid-derived suppressor cells in sepsis: friend or foe?

Cuenca AG, Moldawer LL.

Intensive Care Med. 2012 Jun;38(6):928-30. doi: 10.1007/s00134-012-2575-3. Epub 2012 May 3. No abstract available.


Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.

Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, Warren HS, Cobb JP, Moldawer LL, Davis RW, Maier RV, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program.

Ann Surg. 2012 May;255(5):993-9. doi: 10.1097/SLA.0b013e31824f1ebc.


"Pulling the plug"--management of meconium plug syndrome in neonates.

Cuenca AG, Ali AS, Kays DW, Islam S.

J Surg Res. 2012 Jun 15;175(2):e43-6. doi: 10.1016/j.jss.2012.01.029. Epub 2012 Mar 10.


Obese patients show a depressed cytokine profile following severe blunt injury.

Winfield RD, Delano MJ, Cuenca AG, Cendan JC, Lottenberg L, Efron PA, Maier RV, Remick DG, Moldawer LL, Cuschieri J.

Shock. 2012 Mar;37(3):253-6. doi: 10.1097/SHK.0b013e3182449c0e.


The Glue Grant experience: characterizing the post injury genomic response.

Cuenca AG, Maier RV, Cuschieri J, Moore EE, Moldawer LL, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program.

Eur J Trauma Emerg Surg. 2011 Dec;37(6):549-58. doi: 10.1007/s00068-011-0148-8. Epub 2011 Sep 2.


A genomic storm in critically injured humans.

Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, López MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG; Inflammation and Host Response to Injury Large-Scale Collaborative Research Program.

J Exp Med. 2011 Dec 19;208(13):2581-90. doi: 10.1084/jem.20111354. Epub 2011 Nov 21.


Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage.

Warner EA, Kotz KT, Ungaro RF, Abouhamze AS, Lopez MC, Cuenca AG, Kelly-Scumpia KM, Moreno C, O'Malley KA, Lanz JD, Baker HV, Martin LC, Toner M, Tompkins RG, Efron PA, Moldawer LL.

Lab Invest. 2011 Dec;91(12):1787-95. doi: 10.1038/labinvest.2011.94. Epub 2011 Sep 19.


B cells enhance early innate immune responses during bacterial sepsis.

Kelly-Scumpia KM, Scumpia PO, Weinstein JS, Delano MJ, Cuenca AG, Nacionales DC, Wynn JL, Lee PY, Kumagai Y, Efron PA, Akira S, Wasserfall C, Atkinson MA, Moldawer LL.

J Exp Med. 2011 Aug 1;208(8):1673-82. doi: 10.1084/jem.20101715. Epub 2011 Jul 11.


Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.

Delano MJ, Kelly-Scumpia KM, Thayer TC, Winfield RD, Scumpia PO, Cuenca AG, Harrington PB, O'Malley KA, Warner E, Gabrilovich S, Mathews CE, Laface D, Heyworth PG, Ramphal R, Strieter RM, Moldawer LL, Efron PA.

J Immunol. 2011 Jul 15;187(2):911-8. doi: 10.4049/jimmunol.1100588. Epub 2011 Jun 20.


The usefulness of the upper gastrointestinal series in the pediatric patient before anti-reflux procedure or gastrostomy tube placement.

Cuenca AG, Reddy SV, Dickie B, Kays DW, Islam S.

J Surg Res. 2011 Oct;170(2):247-52. doi: 10.1016/j.jss.2011.03.007. Epub 2011 Apr 1.


Critical role for CXC ligand 10/CXC receptor 3 signaling in the murine neonatal response to sepsis.

Cuenca AG, Wynn JL, Kelly-Scumpia KM, Scumpia PO, Vila L, Delano MJ, Mathews CE, Wallet SM, Reeves WH, Behrns KE, Nacionales DC, Efron PA, Kunkel SL, Moldawer LL.

Infect Immun. 2011 Jul;79(7):2746-54. doi: 10.1128/IAI.01291-10. Epub 2011 Apr 25.


Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.

Delano MJ, Thayer T, Gabrilovich S, Kelly-Scumpia KM, Winfield RD, Scumpia PO, Cuenca AG, Warner E, Wallet SM, Wallet MA, O'Malley KA, Ramphal R, Clare-Salzer M, Efron PA, Mathews CE, Moldawer LL.

J Immunol. 2011 Jan 1;186(1):195-202. doi: 10.4049/jimmunol.1002104. Epub 2010 Nov 24.


A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma.

Cuenca AG, Delano MJ, Kelly-Scumpia KM, Moreno C, Scumpia PO, Laface DM, Heyworth PG, Efron PA, Moldawer LL.

Mol Med. 2011 Mar-Apr;17(3-4):281-92. doi: 10.2119/molmed.2010.00178. Epub 2010 Nov 12. Review.


Cecal ligation and puncture.

Cuenca AG, Delano MJ, Kelly-Scumpia KM, Moldawer LL, Efron PA.

Curr Protoc Immunol. 2010 Nov;Chapter 19:Unit 19.13. doi: 10.1002/0471142735.im1913s91.


Do Tregs link sepsis to tumor growth?

Cuenca AG, Moldawer LL.

Blood. 2010 Jun 3;115(22):4324-5. doi: 10.1182/blood-2010-03-271379. No abstract available.


Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling.

Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, Al-Quran S, Bovio I, Akira S, Kumagai Y, Moldawer LL.

J Immunol. 2010 Mar 1;184(5):2247-51. doi: 10.4049/jimmunol.0903652. Epub 2010 Feb 3.


Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10.

Kelly-Scumpia KM, Scumpia PO, Delano MJ, Weinstein JS, Cuenca AG, Wynn JL, Moldawer LL.

J Exp Med. 2010 Feb 15;207(2):319-26. doi: 10.1084/jem.20091959. Epub 2010 Jan 13.


Equestrian injuries in children.

Cuenca AG, Wiggins A, Chen MK, Kays DW, Islam S, Beierle EA.

J Pediatr Surg. 2009 Jan;44(1):148-50. doi: 10.1016/j.jpedsurg.2008.10.025.


Pulmonary surgery in cystic fibrosis.

Cuenca AG, Beierle EA.

Semin Pediatr Surg. 2008 Feb;17(1):60-5. Review.


Emerging implications of nanotechnology on cancer diagnostics and therapeutics.

Cuenca AG, Jiang H, Hochwald SN, Delano M, Cance WG, Grobmyer SR.

Cancer. 2006 Aug 1;107(3):459-66. Review.


Calorie restriction influences cell cycle protein expression and DNA synthesis during liver regeneration.

Cuenca AG, Cress WD, Good RA, Marikar Y, Engelman RW.

Exp Biol Med (Maywood). 2001 Dec;226(11):1061-7.


Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression.

Sotomayor EM, Borrello I, Rattis FM, Cuenca AG, Abrams J, Staveley-O'Carroll K, Levitsky HI.

Blood. 2001 Aug 15;98(4):1070-7.


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