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Items: 1 to 50 of 271

1.

Stochastic Modeling of Radiation-induced Dendritic Damage on in silico Mouse Hippocampal Neurons.

Cacao E, Parihar VK, Limoli CL, Cucinotta FA.

Sci Rep. 2018 Apr 3;8(1):5494. doi: 10.1038/s41598-018-23855-9.

2.

Biophysics Model of Heavy-Ion Degradation of Neuron Morphology in Mouse Hippocampal Granular Cell Layer Neurons.

Alp M, Cucinotta FA.

Radiat Res. 2018 Mar;189(3):312-325. doi: 10.1667/RR14923.1.

PMID:
29502499
3.

Dynamical modeling approach to risk assessment for radiogenic leukemia among astronauts engaged in interplanetary space missions.

Smirnova OA, Cucinotta FA.

Life Sci Space Res (Amst). 2018 Feb;16:76-83. doi: 10.1016/j.lssr.2017.12.002. Epub 2017 Dec 21.

PMID:
29475522
4.

Editorial: Charged Particles in Oncology.

Durante M, Cucinotta FA, Loeffler JS.

Front Oncol. 2017 Dec 8;7:301. doi: 10.3389/fonc.2017.00301. eCollection 2017. No abstract available.

5.

Track structure model of microscopic energy deposition by protons and heavy ions in segments of neuronal cell dendrites represented by cylinders or spheres.

Alp M, Cucinotta FA.

Life Sci Space Res (Amst). 2017 May;13:27-38. doi: 10.1016/j.lssr.2017.03.004. Epub 2017 Apr 2.

6.

Predictions of space radiation fatality risk for exploration missions.

Cucinotta FA, To K, Cacao E.

Life Sci Space Res (Amst). 2017 May;13:1-11. doi: 10.1016/j.lssr.2017.01.005. Epub 2017 Feb 1.

7.

Non-Targeted Effects Models Predict Significantly Higher Mars Mission Cancer Risk than Targeted Effects Models.

Cucinotta FA, Cacao E.

Sci Rep. 2017 May 12;7(1):1832. doi: 10.1038/s41598-017-02087-3.

8.

Modeling Heavy-Ion Impairment of Hippocampal Neurogenesis after Acute and Fractionated Irradiation.

Cacao E, Cucinotta FA.

Radiat Res. 2016 Dec;186(6):624-637. doi: 10.1667/RR14569.1. Epub 2016 Dec 7.

9.

Skin Response to Single and Fractionated Irradiation: Dynamic Modeling Approach.

Smirnova OA, Cucinotta FA.

Health Phys. 2016 Dec;111(6):513-527.

PMID:
27798476
10.

No evidence for an increase in circulatory disease mortality in astronauts following space radiation exposures.

Cucinotta FA, Hamada N, Little MP.

Life Sci Space Res (Amst). 2016 Aug;10:53-6. doi: 10.1016/j.lssr.2016.08.002. Epub 2016 Aug 20.

PMID:
27662788
11.

Relative Biological Effectiveness of HZE Particles for Chromosomal Exchanges and Other Surrogate Cancer Risk Endpoints.

Cacao E, Hada M, Saganti PB, George KA, Cucinotta FA.

PLoS One. 2016 Apr 25;11(4):e0153998. doi: 10.1371/journal.pone.0153998. eCollection 2016.

12.

Harderian Gland Tumorigenesis: Low-Dose and LET Response.

Chang PY, Cucinotta FA, Bjornstad KA, Bakke J, Rosen CJ, Du N, Fairchild DG, Cacao E, Blakely EA.

Radiat Res. 2016 May;185(5):449-60. doi: 10.1667/RR14335.1. Epub 2016 Apr 19.

PMID:
27092765
13.

Modeling Impaired Hippocampal Neurogenesis after Radiation Exposure.

Cacao E, Cucinotta FA.

Radiat Res. 2016 Mar;185(3):319-31. doi: 10.1667/RR14289.S1. Epub 2016 Mar 4.

PMID:
26943452
14.

Space Radiation Quality Factors and the Delta Ray Dose and Dose-Rate Reduction Effectiveness Factor.

Cucinotta FA, Cacao E, Alp M.

Health Phys. 2016 Mar;110(3):262-6. doi: 10.1097/HP.0000000000000442.

PMID:
26808878
15.

Biological Effectiveness of Accelerated Protons for Chromosome Exchanges.

George KA, Hada M, Cucinotta FA.

Front Oncol. 2015 Oct 19;5:226. doi: 10.3389/fonc.2015.00226. eCollection 2015.

16.

Sixteenth International Symposium on Microdosimetry.

Cherubini R, Cucinotta FA, Menzel HG, O'Neill P.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):1-2. doi: 10.1093/rpd/ncv388. No abstract available.

PMID:
26371335
17.

Irradiation of Neurons with High-Energy Charged Particles: An In Silico Modeling Approach.

Alp M, Parihar VK, Limoli CL, Cucinotta FA.

PLoS Comput Biol. 2015 Aug 7;11(8):e1004428. doi: 10.1371/journal.pcbi.1004428. eCollection 2015 Aug.

18.

What happens to your brain on the way to Mars.

Parihar VK, Allen B, Tran KK, Macaraeg TG, Chu EM, Kwok SF, Chmielewski NN, Craver BM, Baulch JE, Acharya MM, Cucinotta FA, Limoli CL.

Sci Adv. 2015 May 1;1(4). pii: e1400256.

19.

Safe days in space with acceptable uncertainty from space radiation exposure.

Cucinotta FA, Alp M, Rowedder B, Kim MH.

Life Sci Space Res (Amst). 2015 Apr;5:31-8. doi: 10.1016/j.lssr.2015.04.002. Epub 2015 Apr 13.

20.

Defining the Biological Effectiveness of Components of High-LET Track Structure.

Sridharan DM, Chappell LJ, Whalen MK, Cucinotta FA, Pluth JM.

Radiat Res. 2015 Jul;184(1):105-19. Epub 2015 Jun 26.

PMID:
26114329
21.

Issues for Simulation of Galactic Cosmic Ray Exposures for Radiobiological Research at Ground-Based Accelerators.

Kim MH, Rusek A, Cucinotta FA.

Front Oncol. 2015 Jun 4;5:122. doi: 10.3389/fonc.2015.00122. eCollection 2015.

22.

HEMODOSE: A Biodosimetry Tool Based on Multi-type Blood Cell Counts.

Hu S, Blakely WF, Cucinotta FA.

Health Phys. 2015 Jul;109(1):54-68. doi: 10.1097/HP.0000000000000295.

23.

Simulation of the radiolysis of water using Green's functions of the diffusion equation.

Plante I, Cucinotta FA.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):24-8. doi: 10.1093/rpd/ncv179. Epub 2015 Apr 20.

PMID:
25897139
24.

Biophysics of NASA radiation quality factors.

Cucinotta FA.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):282-9. doi: 10.1093/rpd/ncv144. Epub 2015 Apr 16. Review.

PMID:
25883309
25.

Binary-Encounter-Bethe ionisation cross sections for simulation of DNA damage by the direct effect of ionising radiation.

Plante I, Cucinotta FA.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):19-23. doi: 10.1093/rpd/ncv143. Epub 2015 Apr 13.

PMID:
25870431
26.

A new approach to reduce uncertainties in space radiation cancer risk predictions.

Cucinotta FA.

PLoS One. 2015 Mar 19;10(3):e0120717. doi: 10.1371/journal.pone.0120717. eCollection 2015.

27.

Understanding cancer development processes after HZE-particle exposure: roles of ROS, DNA damage repair and inflammation.

Sridharan DM, Asaithamby A, Bailey SM, Costes SV, Doetsch PW, Dynan WS, Kronenberg A, Rithidech KN, Saha J, Snijders AM, Werner E, Wiese C, Cucinotta FA, Pluth JM.

Radiat Res. 2015 Jan;183(1):1-26. doi: 10.1667/RR13804.1. Epub 2015 Jan 7. Review.

PMID:
25564719
28.

Basic criteria, epidemiology, radiobiology, and risk (program area committee 1)-session Q&A.

Preston RJ, Cucinotta FA, Simon SL.

Health Phys. 2015 Feb;108(2):145-8. doi: 10.1097/HP.0000000000000253. No abstract available.

PMID:
25551495
29.

Review of NASA approach to space radiation risk assessments for Mars exploration.

Cucinotta FA.

Health Phys. 2015 Feb;108(2):131-42. doi: 10.1097/HP.0000000000000255. Review.

PMID:
25551493
30.

Induction of chromosomal aberrations at fluences of less than one HZE particle per cell nucleus.

Hada M, Chappell LJ, Wang M, George KA, Cucinotta FA.

Radiat Res. 2014 Oct;182(4):368-79. doi: 10.1667/RR13721.1. Epub 2014 Sep 17.

PMID:
25229974
31.

Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing.

Wang H, Wang X, Chen G, Zhang X, Tang X, Park D, Cucinotta FA, Yu DS, Deng X, Dynan WS, Doetsch PW, Wang Y.

J Biol Chem. 2014 Oct 31;289(44):30635-44. doi: 10.1074/jbc.M114.604959. Epub 2014 Sep 10.

32.

New tricks for an old fox: impact of TGFβ on the DNA damage response and genomic stability.

Barcellos-Hoff MH, Cucinotta FA.

Sci Signal. 2014 Sep 2;7(341):re5. doi: 10.1126/scisignal.2005474. Review.

PMID:
25185158
33.

Biological characterization of low-energy ions with high-energy deposition on human cells.

Saha J, Wilson P, Thieberger P, Lowenstein D, Wang M, Cucinotta FA.

Radiat Res. 2014 Sep;182(3):282-91. doi: 10.1667/RR13747.1. Epub 2014 Aug 6. Erratum in: Radiat Res. 2014 Oct;182(4);e47-8.

PMID:
25098728
34.

Dynamics of acutely irradiated skin epidermal epithelium in swine: modeling studies.

Smirnova OA, Hu S, Cucinotta FA.

Health Phys. 2014 Jul;107(1):47-59. doi: 10.1097/HP.0000000000000058.

PMID:
24849903
35.

Space radiation risks for astronauts on multiple International Space Station missions.

Cucinotta FA.

PLoS One. 2014 Apr 23;9(4):e96099. doi: 10.1371/journal.pone.0096099. eCollection 2014.

36.

Analysis of the lymphocytopoiesis dynamics in nonirradiated and irradiated humans: a modeling approach.

Smirnova OA, Hu S, Cucinotta FA.

Radiat Res. 2014 Mar;181(3):240-50. doi: 10.1667/RR13256.1. Epub 2014 Mar 27.

PMID:
24673256
37.

Generalized time-dependent model of radiation-induced chromosomal aberrations in normal and repair-deficient human cells.

Ponomarev AL, George K, Cucinotta FA.

Radiat Res. 2014 Mar;181(3):284-92. doi: 10.1667/RR13303.1. Epub 2014 Mar 10.

PMID:
24611656
38.

Modeling damage complexity-dependent non-homologous end-joining repair pathway.

Li Y, Reynolds P, O'Neill P, Cucinotta FA.

PLoS One. 2014 Feb 10;9(2):e85816. doi: 10.1371/journal.pone.0085816. eCollection 2014.

39.

OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation.

Ng WL, Chen G, Wang M, Wang H, Story M, Shay JW, Zhang X, Wang J, Amin AR, Hu B, Cucinotta FA, Wang Y.

Cell Death Dis. 2014 Jan 23;5:e1024. doi: 10.1038/cddis.2013.563.

40.

Mars' surface radiation environment measured with the Mars Science Laboratory's Curiosity rover.

Hassler DM, Zeitlin C, Wimmer-Schweingruber RF, Ehresmann B, Rafkin S, Eigenbrode JL, Brinza DE, Weigle G, Böttcher S, Böhm E, Burmeister S, Guo J, Köhler J, Martin C, Reitz G, Cucinotta FA, Kim MH, Grinspoon D, Bullock MA, Posner A, Gómez-Elvira J, Vasavada A, Grotzinger JP; MSL Science Team.

Science. 2014 Jan 24;343(6169):1244797. doi: 10.1126/science.1244797. Epub 2013 Dec 9.

PMID:
24324275
41.

Epidermal homeostasis and radiation responses in a multiscale tissue modeling framework.

Hu S, Cucinotta FA.

Integr Biol (Camb). 2014 Jan;6(1):76-89. doi: 10.1039/c3ib40141c.

PMID:
24270511
42.

Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.

Saha J, Wang M, Cucinotta FA.

DNA Repair (Amst). 2013 Dec;12(12):1143-51. doi: 10.1016/j.dnarep.2013.10.004. Epub 2013 Nov 12.

PMID:
24238855
43.

How safe is safe enough? Radiation risk for a human mission to Mars.

Cucinotta FA, Kim MH, Chappell LJ, Huff JL.

PLoS One. 2013 Oct 16;8(10):e74988. doi: 10.1371/journal.pone.0074988. eCollection 2013.

44.

Calculation of the energy deposition in nanovolumes by protons and HZE particles: geometric patterns of initial distributions of DNA repair foci.

Plante I, Ponomarev AL, Cucinotta FA.

Phys Med Biol. 2013 Sep 21;58(18):6393-405. doi: 10.1088/0031-9155/58/18/6393. Epub 2013 Sep 2.

PMID:
23999659
45.

ICRP, 123. Assessment of radiation exposure of astronauts in space. ICRP Publication 123.

Task Group on Radiation Protection in Space, ICRP Committee 2, Dietze G, Bartlett DT, Cool DA, Cucinotta FA, Jia X, McAulay IR, Pelliccioni M, Petrov V, Reitz G, Sato T.

Ann ICRP. 2013 Aug;42(4):1-339. doi: 10.1016/j.icrp.2013.05.004.

PMID:
23958389
46.

Measurements of energetic particle radiation in transit to Mars on the Mars Science Laboratory.

Zeitlin C, Hassler DM, Cucinotta FA, Ehresmann B, Wimmer-Schweingruber RF, Brinza DE, Kang S, Weigle G, Böttcher S, Böhm E, Burmeister S, Guo J, Köhler J, Martin C, Posner A, Rafkin S, Reitz G.

Science. 2013 May 31;340(6136):1080-4. doi: 10.1126/science.1235989.

47.

Biological effectiveness of accelerated particles for the induction of chromosome damage: track structure effects.

George KA, Hada M, Chappell L, Cucinotta FA.

Radiat Res. 2013 Jul;180(1):25-33. doi: 10.1667/RR3291.1. Epub 2013 May 21.

PMID:
23692480
48.

Smad7 foci are present in micronuclei induced by heavy particle radiation.

Wang M, Saha J, Cucinotta FA.

Mutat Res. 2013 Aug 30;756(1-2):108-14. doi: 10.1016/j.mrgentox.2013.04.011. Epub 2013 Apr 30.

PMID:
23643526
49.

Cytogenetic damage in the blood lymphocytes of astronauts: effects of repeat long-duration space missions.

George K, Rhone J, Beitman A, Cucinotta FA.

Mutat Res. 2013 Aug 30;756(1-2):165-9. doi: 10.1016/j.mrgentox.2013.04.007. Epub 2013 Apr 29.

50.

Comment on "dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors" (Radiat. Environ. Biophys (2012) 51:165-178) by Schöllnberger et al.

Little MP, Azizova TV, Bazyka D, Bouffler SD, Cardis E, Chekin S, Chumak VV, Cucinotta FA, de Vathaire F, Hall P, Harrison JD, Hildebrandt G, Ivanov V, Kashcheev VV, Klymenko SV, Laurent O, Ozasa K, Tapio S, Taylor AM, Tzoulaki I, Vandoolaeghe WL, Wakeford R, Zablotska L, Zhang W, Lipshultz SE.

Radiat Environ Biophys. 2013 Mar;52(1):157-9. doi: 10.1007/s00411-012-0453-6. Epub 2013 Jan 8. No abstract available.

PMID:
23296519

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