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Items: 49

1.

Neutral Diclofenac Causes Remarkable Changes in Phosphatidylcholine Bilayers: Relevance for Gastric Toxicity Mechanisms.

Pereira-Leite C, Jamal SK, Almeida JP, Coutinho A, Prieto M, Cuccovia IM, Nunes C, Reis S.

Mol Pharmacol. 2020 Apr;97(4):295-303. doi: 10.1124/mol.119.118299. Epub 2020 Feb 26.

PMID:
32102968
2.

Dehydration Determines Hydrotropic Ion Affinity for Zwitterionic Micelles.

Mortara L, Chaimovich H, Cuccovia IM, Horinek D, Lima FS.

J Chem Inf Model. 2020 Feb 24;60(2):604-610. doi: 10.1021/acs.jcim.9b00870. Epub 2019 Dec 19.

PMID:
31790243
3.

Characterization of phospholipid vesicles containing lauric acid: physicochemical basis for process and product development.

Farkuh L, Hennies PT, Nunes C, Reis S, Barreiros L, Segundo MA, Oseliero Filho PL, Oliveira CLP, Cassago A, Portugal RV, Muramoto RA, Carretero GPB, Schreier S, Chaimovich H, Cuccovia IM.

Heliyon. 2019 Nov 1;5(10):e02648. doi: 10.1016/j.heliyon.2019.e02648. eCollection 2019 Oct.

4.

Where do we aspire to publish? A position paper on scientific communication in biochemistry and molecular biology.

Baptista MS, Alves MJM, Arantes GM, Armelin HA, Augusto O, Baldini RL, Basseres DS, Bechara EJH, Bruni-Cardoso A, Chaimovich H, Colepicolo Neto P, Colli W, Cuccovia IM, Da-Silva AM, Di Mascio P, Farah SC, Ferreira C, Forti FL, Giordano RJ, Gomes SL, Gueiros Filho FJ, Hoch NC, Hotta CT, Labriola L, Lameu C, Machini MT, Malnic B, Marana SR, Medeiros MHG, Meotti FC, Miyamoto S, Oliveira CC, Souza-Pinto NC, Reis EM, Ronsein GE, Salinas RK, Schechtman D, Schreier S, Setubal JC, Sogayar MC, Souza GM, Terra WR, Truzzi DR, Ulrich H, Verjovski-Almeida S, Winck FV, Zingales B, Kowaltowski AJ.

Braz J Med Biol Res. 2019;52(9):e8935. doi: 10.1590/1414-431X20198935. Epub 2019 Aug 29.

5.

Binding and Flip as Initial Steps for BP-100 Antimicrobial Actions.

Park P, Franco LR, Chaimovich H, Coutinho K, Cuccovia IM, Lima FS.

Sci Rep. 2019 Jun 13;9(1):8622. doi: 10.1038/s41598-019-45075-5.

6.

Licofelone-DPPC Interactions: Putting Membrane Lipids on the Radar of Drug Development.

Pereira-Leite C, Lopes-de-Campos D, Fontaine P, Cuccovia IM, Nunes C, Reis S.

Molecules. 2019 Jan 31;24(3). pii: E516. doi: 10.3390/molecules24030516.

7.

Violacein Targets the Cytoplasmic Membrane of Bacteria.

Cauz ACG, Carretero GPB, Saraiva GKV, Park P, Mortara L, Cuccovia IM, Brocchi M, Gueiros-Filho FJ.

ACS Infect Dis. 2019 Apr 12;5(4):539-549. doi: 10.1021/acsinfecdis.8b00245. Epub 2019 Feb 12.

PMID:
30693760
8.

Specific Ion Effects on Zwitterionic Micelles Are Independent of Interfacial Hydration Changes.

Mortara L, Lima FDS, Cuccovia IM, Nazet A, Horinek D, Buchner R, Chaimovich H.

Langmuir. 2018 Sep 18;34(37):11049-11057. doi: 10.1021/acs.langmuir.8b02115. Epub 2018 Sep 4.

PMID:
30126270
9.

Can NO-indomethacin counteract the topical gastric toxicity induced by indomethacin interactions with phospholipid bilayers?

Pereira-Leite C, Nunes C, Bozelli JC Jr, Schreier S, Kamma-Lorger CS, Cuccovia IM, Reis S.

Colloids Surf B Biointerfaces. 2018 Sep 1;169:375-383. doi: 10.1016/j.colsurfb.2018.05.019. Epub 2018 May 23.

PMID:
29803153
10.

Acemetacin-phosphatidylcholine interactions are determined by the drug ionization state.

Pereira-Leite C, Nunes C, Grahl D, Bozelli JC, Schreier S, Kamma-Lorger CS, Cuccovia IM, Reis S.

Phys Chem Chem Phys. 2018 May 30;20(21):14398-14409. doi: 10.1039/c8cp01698d.

PMID:
29770409
11.

Synthesis, biophysical and functional studies of two BP100 analogues modified by a hydrophobic chain and a cyclic peptide.

Carretero GPB, Saraiva GKV, Cauz ACG, Rodrigues MA, Kiyota S, Riske KA, Dos Santos AA, Pinatto-Botelho MF, Bemquerer MP, Gueiros-Filho FJ, Chaimovich H, Schreier S, Cuccovia IM.

Biochim Biophys Acta Biomembr. 2018 Aug;1860(8):1502-1516. doi: 10.1016/j.bbamem.2018.05.003. Epub 2018 May 9.

12.

HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pRB-dependent manner.

Rabachini T, Boccardo E, Andrade R, Perez KR, Nonogaki S, Cuccovia IM, Villa LL.

BMC Cancer. 2018 Apr 27;18(1):485. doi: 10.1186/s12885-018-4392-8.

13.

Ion dehydration controls adsorption at the micellar interface: hydrotropic ions.

Lima FS, Andrade MFC, Mortara L, Gustavo Dias L, Cuccovia IM, Chaimovich H.

Phys Chem Chem Phys. 2017 Nov 22;19(45):30658-30666. doi: 10.1039/c7cp05283a.

PMID:
29119186
14.

Counting ions and other nucleophiles at surfaces by chemical trapping.

Cuccovia IM, da Silva Lima F, Chaimovich H.

Biophys Rev. 2017 Oct;9(5):617-631. doi: 10.1007/s12551-017-0299-x. Epub 2017 Aug 29. Review.

15.

CCR2 contributes to the recruitment of monocytes and leads to kidney inflammation and fibrosis development.

Braga TT, Correa-Costa M, Silva RC, Cruz MC, Hiyane MI, da Silva JS, Perez KR, Cuccovia IM, Camara NOS.

Inflammopharmacology. 2018 Apr;26(2):403-411. doi: 10.1007/s10787-017-0317-4. Epub 2017 Feb 6.

PMID:
28168553
16.

Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety.

Pereira-Leite C, Nunes C, Jamal SK, Cuccovia IM, Reis S.

Med Res Rev. 2017 Jul;37(4):802-859. doi: 10.1002/med.21424. Epub 2016 Dec 22. Review.

PMID:
28005273
17.

Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development.

Braga TT, Correa-Costa M, Azevedo H, Silva RC, Cruz MC, Almeida ME, Hiyane MI, Moreira-Filho CA, Santos MF, Perez KR, Cuccovia IM, Camara NO.

Immun Inflamm Dis. 2016 Jul 21;4(3):300-14. doi: 10.1002/iid3.114. eCollection 2016 Sep.

18.

Potential antitumor activity of novel DODAC/PHO-S liposomes.

Luna AC, Saraiva GK, Filho OM, Chierice GO, Neto SC, Cuccovia IM, Maria DA.

Int J Nanomedicine. 2016 Apr 18;11:1577-91. doi: 10.2147/IJN.S90850. eCollection 2016.

19.

Molecular Dynamics Simulations of the Initial-State Predict Product Distributions of Dediazoniation of Aryldiazonium in Binary Solvents.

Cruz GN, Lima FS, Dias LG, El Seoud OA, Horinek D, Chaimovich H, Cuccovia IM.

J Org Chem. 2015 Sep 4;80(17):8637-42. doi: 10.1021/acs.joc.5b01289. Epub 2015 Aug 20.

PMID:
26263052
20.

Sodium triflate decreases interaggregate repulsion and induces phase separation in cationic micelles.

Lima FS, Cuccovia IM, Buchner R, Antunes FE, Lindman B, Miguel MG, Horinek D, Chaimovich H.

Langmuir. 2015 Mar 10;31(9):2609-14. doi: 10.1021/la5049216. Epub 2015 Feb 26.

PMID:
25689018
21.

In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria.

Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE.

PLoS Pathog. 2015 Feb 6;11(2):e1004598. doi: 10.1371/journal.ppat.1004598. eCollection 2015 Feb.

22.

Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzyme.

Coelho FR, Iqbal A, Linares E, Silva DF, Lima FS, Cuccovia IM, Augusto O.

J Biol Chem. 2014 Oct 31;289(44):30690-701. doi: 10.1074/jbc.M114.586370. Epub 2014 Sep 18.

23.

Macrophage trafficking as key mediator of adenine-induced kidney injury.

Correa-Costa M, Braga TT, Felizardo RJ, Andrade-Oliveira V, Perez KR, Cuccovia IM, Hiyane MI, da Silva JS, Câmara NO.

Mediators Inflamm. 2014;2014:291024. doi: 10.1155/2014/291024. Epub 2014 Jul 16.

24.

Peptide:lipid ratio and membrane surface charge determine the mechanism of action of the antimicrobial peptide BP100. Conformational and functional studies.

Manzini MC, Perez KR, Riske KA, Bozelli JC Jr, Santos TL, da Silva MA, Saraiva GK, Politi MJ, Valente AP, Almeida FC, Chaimovich H, Rodrigues MA, Bemquerer MP, Schreier S, Cuccovia IM.

Biochim Biophys Acta. 2014 Jul;1838(7):1985-99. doi: 10.1016/j.bbamem.2014.04.004. Epub 2014 Apr 15.

25.

Chimeric proteins combining phosphatase and cellulose-binding activities: proof-of-concept and application in the hydrolysis of paraoxon.

Gonçalves LM, Chaimovich H, Cuccovia IM, Marana SR.

Protein Pept Lett. 2014 May;21(5):468-75.

PMID:
24555432
26.

Molecular dynamics shows that ion pairing and counterion anchoring control the properties of triflate micelles: a comparison with triflate at the air/water interface.

Lima FS, Chaimovich H, Cuccovia IM, Horinek D.

Langmuir. 2014 Feb 11;30(5):1239-49. doi: 10.1021/la404260y. Epub 2014 Jan 27.

PMID:
24467445
27.

Dielectric relaxation spectroscopy shows a sparingly hydrated interface and low counterion mobility in triflate micelles.

Lima FS, Chaimovich H, Cuccovia IM, Buchner R.

Langmuir. 2013 Aug 13;29(32):10037-46. doi: 10.1021/la401728g. Epub 2013 Jul 31.

PMID:
23899188
28.

Effect of counterions on the shape, hydration, and degree of order at the interface of cationic micelles: the triflate case.

Lima FS, Cuccovia IM, Horinek D, Amaral LQ, Riske KA, Schreier S, Salinas RK, Bastos EL, Pires PA, Bozelli JC Jr, Favaro DC, Rodrigues AC, Dias LG, El Seoud OA, Chaimovich H.

Langmuir. 2013 Apr 2;29(13):4193-203. doi: 10.1021/la304658e. Epub 2013 Mar 22.

PMID:
23473070
29.

Low-dose gamma irradiation of food protein increases its allergenicity in a chronic oral challenge.

Vaz AF, Souza MP, Medeiros PL, Melo AM, Silva-Lucca RA, Santana LA, Oliva ML, Perez KR, Cuccovia IM, Correia MT.

Food Chem Toxicol. 2013 Jan;51:46-52. doi: 10.1016/j.fct.2012.09.011. Epub 2012 Sep 19.

30.

MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages.

Braga TT, Correa-Costa M, Guise YF, Castoldi A, de Oliveira CD, Hyane MI, Cenedeze MA, Teixeira SA, Muscara MN, Perez KR, Cuccovia IM, Pacheco-Silva A, Gonçalves GM, Camara NO.

Mol Med. 2012 Oct 24;18:1231-9. doi: 10.2119/molmed.2012.00131.

31.

Interfacial concentrations of chloride and bromide in zwitterionic micelles with opposite dipoles: experimental determination by chemical trapping and a theoretical description.

de Souza TP, Chaimovich H, Fahr A, Schweitzer B, Agostinho Neto A, Cuccovia IM.

J Colloid Interface Sci. 2012 Apr 1;371(1):62-72. doi: 10.1016/j.jcis.2011.12.072. Epub 2012 Jan 21.

32.

Aqueous dispersions of DMPG in low salt contain leaky vesicles.

Barroso RP, Perez KR, Cuccovia IM, Teresa Lamy M.

Chem Phys Lipids. 2012 Feb;165(2):169-77. doi: 10.1016/j.chemphyslip.2011.12.007. Epub 2011 Dec 20.

33.

Surface activity of the triflate ion at the air/water interface and properties of N,N,N-trimethyl-N-dodecylammonium triflate aqueous solutions.

Lima FS, Maximiano FA, Cuccovia IM, Chaimovich H.

Langmuir. 2011 Apr 19;27(8):4319-23. doi: 10.1021/la2004613. Epub 2011 Mar 17.

PMID:
21413729
34.

HPV16 tumor associated macrophages suppress antitumor T cell responses.

Lepique AP, Daghastanli KR, Cuccovia IM, Villa LL.

Clin Cancer Res. 2009 Jul 1;15(13):4391-400. doi: 10.1158/1078-0432.CCR-09-0489. Epub 2009 Jun 23.

35.

Effects of micelles and vesicles on the oximolysis of p-nitrophenyl diphenyl phosphate: A model system for surfactant-based skin-defensive formulations against organophosphates.

Gonçalves LM, Kobayakawa TG, Zanette D, Chaimovich H, Cuccovia IM.

J Pharm Sci. 2009 Mar;98(3):1040-52. doi: 10.1002/jps.21506.

PMID:
18661539
36.

A short proregion of trialysin, a pore-forming protein of Triatoma infestans salivary glands, controls activity by folding the N-terminal lytic motif.

Martins RM, Amino R, Daghastanli KR, Cuccovia IM, Juliano MA, Schenkman S.

FEBS J. 2008 Mar;275(5):994-1002. doi: 10.1111/j.1742-4658.2008.06260.x. Epub 2008 Jan 25.

37.

Effect of cholesterol on the interaction of the amphibian antimicrobial peptide DD K with liposomes.

Verly RM, Rodrigues MA, Daghastanli KR, Denadai AM, Cuccovia IM, Bloch C Jr, Frézard F, Santoro MM, Piló-Veloso D, Bemquerer MP.

Peptides. 2008 Jan;29(1):15-24. Epub 2007 Nov 17.

PMID:
18083275
38.
39.

Plant uncoupling mitochondrial proteins.

Vercesi AE, Borecký J, Maia Ide G, Arruda P, Cuccovia IM, Chaimovich H.

Annu Rev Plant Biol. 2006;57:383-404. Review.

PMID:
16669767
40.

Mechanism of 1,4,5,8-naphthalene tetracarboxylic acid dianhydride hydrolysis and formation in aqueous solution.

Barros TC, Cuccovia IM, Farah JP, Masini JC, Chaimovich H, Politi MJ.

Org Biomol Chem. 2006 Jan 7;4(1):71-82. Epub 2005 Nov 18.

PMID:
16357999
41.

pH at the micellar interface: synthesis of pH probes derived from salicylic acid, acid-base dissociation in sodium dodecyl sulfate micelles, and Poisson-Boltzmann simulation.

Souza TP, Zanette D, Kawanami AE, de Rezende L, Ishiki HM, do Amaral AT, Chaimovich H, Agostinho-Neto A, Cuccovia IM.

J Colloid Interface Sci. 2006 May 1;297(1):292-302. Epub 2005 Dec 6.

PMID:
16337218
42.

Origin of the sphere-to-rod transition in cationic micelles with aromatic counterions: specific ion hydration in the interfacial region matters.

Geng Y, Romsted LS, Froehner S, Zanette D, Magid LJ, Cuccovia IM, Chaimovich H.

Langmuir. 2005 Jan 18;21(2):562-8.

PMID:
15641824
43.
44.

Lactic acid triggers, in vitro, thiomersal to degrade protein in the presence of PLGA microspheres.

Namur JA, Takata CS, Moro AM, Politi MJ, De Araujo PS, Cuccovia IM, Da Costa MH.

Int J Pharm. 2004 Apr 1;273(1-2):1-8.

PMID:
15010124
45.

Effect of liposomes on the rate of alkaline hydrolysis of indomethacin and acemetacin.

Matos C, Chaimovich H, Lima JL, Cuccovia IM, Reis S.

J Pharm Sci. 2001 Mar;90(3):298-309.

PMID:
11170023
47.

Permeation of superoxide anion through the bilayer of vesicles of a synthetic amphiphile.

Gomes LF, Cuccovia IM, Chaimovich H, Barbieri DH, Politi MJ.

Biochim Biophys Acta. 1993 Oct 10;1152(1):78-82.

PMID:
8399308
48.
49.

Effect of lipid membranes on the apparent pK of the local anesthetic tetracaine. Spin label and titration studies.

Schreier S, Frezzatti WA Jr, Araujo PS, Chaimovich H, Cuccovia IM.

Biochim Biophys Acta. 1984 Jan 11;769(1):231-7.

PMID:
6318824

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