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Items: 7


TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.

Rodell CB, Arlauckas SP, Cuccarese MF, Garris CS, Li R, Ahmed MS, Kohler RH, Pittet MJ, Weissleder R.

Nat Biomed Eng. 2018;2:578-588. Epub 2018 May 21.


Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease.

Miller MA, Kim E, Cuccarese MF, Plotkin AL, Prytyskach M, Kohler RH, Pittet MJ, Weissleder R.

Chem Commun (Camb). 2017 Dec 19;54(1):42-45. doi: 10.1039/c7cc07581b.


Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts.

Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R.

Sci Transl Med. 2017 May 31;9(392). pii: eaal0225. doi: 10.1126/scitranslmed.aal0225.


In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.

Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ.

Sci Transl Med. 2017 May 10;9(389). pii: eaal3604. doi: 10.1126/scitranslmed.aal3604.


Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.

Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R.

Nat Commun. 2017 Feb 8;8:14293. doi: 10.1038/ncomms14293.


Cryptocaryol Structure-Activity Relationship Study of Cancer Cell Cytotoxicity and Ability to Stabilize PDCD4.

Cuccarese MF, Wang Y, Beuning PJ, O'Doherty GA.

ACS Med Chem Lett. 2014 Feb 17;5(5):522-6. doi: 10.1021/ml4005039. eCollection 2014 May 8.


A novel use of gentamicin in the ROS-mediated sensitization of NCI-H460 lung cancer cells to various anticancer agents.

Cuccarese MF, Singh A, Amiji M, O'Doherty GA.

ACS Chem Biol. 2013 Dec 20;8(12):2771-7. doi: 10.1021/cb4007024. Epub 2013 Oct 17.

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