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Items: 32

1.

Double-strand break repair through homologous recombination in autosomal-recessive BCL10 deficiency.

García-Gómez S, Chaparro R, Safa A, Van Den Rym A, Martinez-Barricarte R, Lorenzo L, Sánchez-Ramón S, Toledano V, Cubillos-Zapata C, López-Collazo E, Martín-Arranz MD, Martín-Arranz E, Vela M, Gonzalez-Navarro P, Pérez-Martínez A, Casanova JL, Recio MJ, Pérez de Diego R.

J Allergy Clin Immunol. 2019 Jan 18. pii: S0091-6749(19)30017-X. doi: 10.1016/j.jaci.2018.12.1000. [Epub ahead of print] No abstract available.

PMID:
30660642
2.

Age-dependent hypoxia-induced PD-L1 upregulation in patients with obstructive sleep apnoea.

Cubillos-Zapata C, Balbás-García C, Avendaño-Ortiz J, Toledano V, Torres M, Almendros I, Casitas R, Zamarrón E, García-Sánchez A, Feliu J, Aguirre LA, Farre R, López-Collazo E, García-Rio F.

Respirology. 2019 Jan 17. doi: 10.1111/resp.13470. [Epub ahead of print]

PMID:
30656807
3.

Soluble PD-L1 is a potential biomarker of cutaneous melanoma aggressiveness and metastasis in obstructive sleep apnoea patients.

Cubillos-Zapata C, Martínez-García MÁ, Campos-Rodríguez F, Sánchez de la Torre M, Nagore E, Martorell-Calatayud A, Hernández Blasco L, Chiner Vives E, Abad-Capa J, Montserrat JM, Cabriada-Nuño V, Cano-Pumarega I, Corral-Peñafiel J, Diaz-Cambriles T, Mediano O, Somoza-González M, Dalmau-Arias J, Almendros I, Farré R, López-Collazo E, Gozal D, García-Río F; Spanish Sleep Network.

Eur Respir J. 2019 Jan 31;53(2). pii: 1801298. doi: 10.1183/13993003.01298-2018. Print 2019 Feb.

PMID:
30487198
4.

Pseudomonas aeruginosa colonization causes PD-L1 overexpression on monocytes, impairing the adaptive immune response in patients with cystic fibrosis.

Avendaño-Ortiz J, Llanos-González E, Toledano V, Del Campo R, Cubillos-Zapata C, Lozano-Rodríguez R, Ismail A, Prados C, Gómez-Campelo P, Aguirre LA, García-Río F, López-Collazo E.

J Cyst Fibros. 2018 Nov 12. pii: S1569-1993(18)30930-5. doi: 10.1016/j.jcf.2018.11.002. [Epub ahead of print]

PMID:
30442491
5.

PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?

Cantero-Cid R, Casas-Martin J, Hernández-Jiménez E, Cubillos-Zapata C, Varela-Serrano A, Avendaño-Ortiz J, Casarrubios M, Montalbán-Hernández K, Villacañas-Gil I, Guerra-Pastrián L, Peinado B, Marcano C, Aguirre LA, López-Collazo E.

BMC Cancer. 2018 Oct 3;18(1):945. doi: 10.1186/s12885-018-4853-0.

6.

Obstructive Sleep Apnea Monocytes Exhibit High Levels of Vascular Endothelial Growth Factor Secretion, Augmenting Tumor Progression.

Cubillos-Zapata C, Hernández-Jiménez E, Avendaño-Ortiz J, Toledano V, Varela-Serrano A, Fernández-Navarro I, Casitas R, Carpio C, Aguirre LA, García-Río F, López-Collazo E.

Mediators Inflamm. 2018 May 28;2018:7373921. doi: 10.1155/2018/7373921. eCollection 2018.

7.

The effect of treatment for sleep apnoea on determinants of blood pressure control.

Casitas R, Martínez-Cerón E, Galera R, Cubillos-Zapata C, González-Villalba MJ, Fernández-Navarro I, Sánchez B, García-Sánchez A, Zamarrón E, García-Río F.

Eur Respir J. 2017 Nov 16;50(5). pii: 1701261. doi: 10.1183/13993003.01261-2017. Print 2017 Nov.

PMID:
29146604
8.

Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea.

Cubillos-Zapata C, Avendaño-Ortiz J, Hernandez-Jimenez E, Toledano V, Casas-Martin J, Varela-Serrano A, Torres M, Almendros I, Casitas R, Fernández-Navarro I, Garcia-Sanchez A, Aguirre LA, Farre R, López-Collazo E, García-Rio F.

Eur Respir J. 2017 Oct 19;50(4). pii: 1700833. doi: 10.1183/13993003.00833-2017. Print 2017 Oct.

PMID:
29051270
9.

PD-L1 Overexpression During Endotoxin Tolerance Impairs the Adaptive Immune Response in Septic Patients via HIF1α.

Avendaño-Ortiz J, Maroun-Eid C, Martín-Quirós A, Toledano V, Cubillos-Zapata C, Gómez-Campelo P, Varela-Serrano A, Casas-Martin J, Llanos-González E, Alvarez E, García-Río F, Aguirre LA, Hernández-Jiménez E, López-Collazo E.

J Infect Dis. 2018 Jan 17;217(3):393-404. doi: 10.1093/infdis/jix279.

PMID:
28973671
10.

A System Dynamics Model to Predict the Human Monocyte Response to Endotoxins.

Álvarez E, Toledano V, Morilla F, Hernández-Jiménez E, Cubillos-Zapata C, Varela-Serrano A, Casas-Martín J, Avendaño-Ortiz J, Aguirre LA, Arnalich F, Maroun-Eid C, Martín-Quirós A, Quintana Díaz M, López-Collazo E.

Front Immunol. 2017 Aug 3;8:915. doi: 10.3389/fimmu.2017.00915. eCollection 2017.

11.

Monocytes inhibit NK activity via TGF-β in patients with obstructive sleep apnoea.

Hernández-Jiménez E, Cubillos-Zapata C, Toledano V, Pérez de Diego R, Fernández-Navarro I, Casitas R, Carpio C, Casas-Martín J, Valentín J, Varela-Serrano A, Avendaño-Ortiz J, Alvarez E, Aguirre LA, Pérez-Martínez A, De Miguel MP, Belda-Iniesta C, García-Río F, López-Collazo E.

Eur Respir J. 2017 Jun 15;49(6). pii: 1602456. doi: 10.1183/13993003.02456-2016. Print 2017 Jun.

12.

Classification of Airflow Limitation Based on z-Score Underestimates Mortality in Patients with Chronic Obstructive Pulmonary Disease.

Tejero E, Prats E, Casitas R, Galera R, Pardo P, Gavilán A, Martínez-Cerón E, Cubillos-Zapata C, Del Peso L, García-Río F.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):298-305. doi: 10.1164/rccm.201611-2265OC.

PMID:
28306326
13.

CC-122 immunomodulatory effects in refractory patients with diffuse large B-cell lymphoma.

Cubillos-Zapata C, Cordoba R, Avendaño-Ortiz J, Arribas-Jiménez C, Hernández-Jiménez E, Toledano V, Villaescusa T, Moreno V, López-Collazo E.

Oncoimmunology. 2016 Sep 16;5(12):e1231290. doi: 10.1080/2162402X.2016.1231290. eCollection 2016.

14.

Ibrutinib as an antitumor immunomodulator in patients with refractory chronic lymphocytic leukemia.

Cubillos-Zapata C, Avendaño-Ortiz J, Córdoba R, Hernández-Jiménez E, Toledano V, Pérez de Diego R, López-Collazo E.

Oncoimmunology. 2016 Oct 20;5(12):e1242544. doi: 10.1080/2162402X.2016.1242544. eCollection 2016.

15.

Circulating Monocytes Exhibit an Endotoxin Tolerance Status after Acute Ischemic Stroke: Mitochondrial DNA as a Putative Explanation for Poststroke Infections.

Hernández-Jiménez E, Gutierrez-Fernández M, Cubillos-Zapata C, Otero-Ortega L, Rodríguez-Frutos B, Toledano V, Martínez-Sánchez P, Fuentes B, Varela-Serrano A, Avendaño-Ortiz J, Blázquez A, Mangas-Guijarro MÁ, Díez-Tejedor E, López-Collazo E.

J Immunol. 2017 Mar 1;198(5):2038-2046. doi: 10.4049/jimmunol.1601594. Epub 2017 Jan 23.

16.

Thalidomide analog CC-122 induces a refractory state in monocytes from patients with diffuse large B cell lymphoma.

Cubillos-Zapata C, Córdoba R, Avendaño-Ortiz J, Lopez-Collazo E.

Leuk Lymphoma. 2017 Aug;58(8):1999-2001. doi: 10.1080/10428194.2016.1272686. Epub 2017 Jan 16. No abstract available. Retraction in: Leuk Lymphoma. 2017 Aug;58(8):I.

PMID:
28093007
17.

Transduction of skin-migrating dendritic cells by human adenovirus 5 occurs via an actin-dependent phagocytic pathway.

Guzman E, Taylor G, Hope J, Herbert R, Cubillos-Zapata C, Charleston B.

J Gen Virol. 2016 Oct;97(10):2703-2718. doi: 10.1099/jgv.0.000581. Epub 2016 Aug 15.

18.

Actin polymerisation after FCγR stimulation of human fibroblasts is BCL10 independent.

Garcia-Gomez S, Alvarez Doforno R, Martinez-Barricarte R, Torres JM, Ferreira Cerdan A, Davila M, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Vallejo-Cremades MT, López-Collazo E, Fernández Arquero M, Sánchez-Ramón S, Casanova JL, Pérez de Diego R.

Clin Immunol. 2016 Feb;163:120-2. doi: 10.1016/j.clim.2016.01.003. Epub 2016 Jan 14.

PMID:
26774590
19.

Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100.

Toledano V, Hernández-Jiménez E, Cubillos-Zapata C, Flandez M, Álvarez E, Varela-Serrano A, Cantero R, Valles G, García-Rio F, López-Collazo E.

Mediators Inflamm. 2015;2015:942517. doi: 10.1155/2015/942517. Epub 2015 Sep 9.

20.

Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity.

Pérez de Diego R, Sánchez-Ramón S, López-Collazo E, Martínez-Barricarte R, Cubillos-Zapata C, Ferreira Cerdán A, Casanova JL, Puel A.

J Allergy Clin Immunol. 2015 Nov;136(5):1139-49. doi: 10.1016/j.jaci.2015.06.031. Epub 2015 Aug 12. Review.

21.

Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.

Shalova IN, Lim JY, Chittezhath M, Zinkernagel AS, Beasley F, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Rapisarda A, Chen J, Duan K, Yang H, Poidinger M, Melillo G, Nizet V, Arnalich F, López-Collazo E, Biswas SK.

Immunity. 2015 Mar 17;42(3):484-98. doi: 10.1016/j.immuni.2015.02.001. Epub 2015 Mar 3.

22.

Response to "In vivo attenuation and genetic evolution of a ST247-SCCmecI MRSA clone after 13 years of pathogenic bronchopulmonary colonization in a patient with cystic fibrosis: implications of the innate immune response".

López-Collazo E, Jurado T, de Dios Caballero J, Pérez-Vázquez M, Vindel A, Hernández-Jiménez E, Tamames J, Cubillos-Zapata C, Manrique M, Tobes R, Máiz L, Cantón R, Baquero F, del Campo R.

Mucosal Immunol. 2015 May;8(3):697-8. doi: 10.1038/mi.2015.10. Epub 2015 Mar 4. No abstract available.

PMID:
25736458
23.

Chronic lymphocytic leukemia: a paradigm of innate immune cross-tolerance.

Jurado-Camino T, Córdoba R, Esteban-Burgos L, Hernández-Jiménez E, Toledano V, Hernandez-Rivas JA, Ruiz-Sainz E, Cobo T, Siliceo M, Perez de Diego R, Belda C, Cubillos-Zapata C, López-Collazo E.

J Immunol. 2015 Jan 15;194(2):719-27. doi: 10.4049/jimmunol.1402272. Epub 2014 Dec 10.

24.

Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity.

Torres JM, Martinez-Barricarte R, García-Gómez S, Mazariegos MS, Itan Y, Boisson B, Rholvarez R, Jiménez-Reinoso A, del Pino L, Rodríguez-Pena R, Ferreira A, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Díaz-Almirón M, López-Collazo E, Unzueta-Roch JL, Sánchez-Ramón S, Regueiro JR, López-Granados E, Casanova JL, Pérez de Diego R.

J Clin Invest. 2014 Dec;124(12):5239-48. doi: 10.1172/JCI77493. Epub 2014 Nov 3.

25.

NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.

Cubillos-Zapata C, Hernández-Jiménez E, Toledano V, Esteban-Burgos L, Fernández-Ruíz I, Gómez-Piña V, Del Fresno C, Siliceo M, Prieto-Chinchiña P, Pérez de Diego R, Boscá L, Fresno M, Arnalich F, López-Collazo E.

J Immunol. 2014 Oct 15;193(8):4195-202. doi: 10.4049/jimmunol.1400721. Epub 2014 Sep 15.

26.

In vivo attenuation and genetic evolution of a ST247-SCCmecI MRSA clone after 13 years of pathogenic bronchopulmonary colonization in a patient with cystic fibrosis: implications of the innate immune response.

López-Collazo E, Jurado T, de Dios Caballero J, Pérez-Vázquez M, Vindel A, Hernández-Jiménez E, Tamames J, Cubillos-Zapata C, Manrique M, Tobes R, Máiz L, Cantón R, Baquero F, Del Campo R.

Mucosal Immunol. 2015 Mar;8(2):362-71. doi: 10.1038/mi.2014.73. Epub 2014 Aug 13.

PMID:
25118167
27.

Bovine γδ T cells are a major regulatory T cell subset.

Guzman E, Hope J, Taylor G, Smith AL, Cubillos-Zapata C, Charleston B.

J Immunol. 2014 Jul 1;193(1):208-22. doi: 10.4049/jimmunol.1303398. Epub 2014 Jun 2.

28.

Mitochondrial DAMPs induce endotoxin tolerance in human monocytes: an observation in patients with myocardial infarction.

Fernández-Ruiz I, Arnalich F, Cubillos-Zapata C, Hernández-Jiménez E, Moreno-González R, Toledano V, Fernández-Velasco M, Vallejo-Cremades MT, Esteban-Burgos L, de Diego RP, Llamas-Matias MA, García-Arumi E, Martí R, Boscá L, Andreu AL, López-Sendón JL, López-Collazo E.

PLoS One. 2014 May 5;9(5):e95073. doi: 10.1371/journal.pone.0095073. eCollection 2014.

29.

Biofilm vs. planktonic bacterial mode of growth: which do human macrophages prefer?

Hernández-Jiménez E, Del Campo R, Toledano V, Vallejo-Cremades MT, Muñoz A, Largo C, Arnalich F, García-Rio F, Cubillos-Zapata C, López-Collazo E.

Biochem Biophys Res Commun. 2013 Nov 29;441(4):947-52. doi: 10.1016/j.bbrc.2013.11.012. Epub 2013 Nov 14.

PMID:
24239884
30.

Modified vaccinia virus Ankara-based vaccine vectors induce apoptosis in dendritic cells draining from the skin via both the extrinsic and intrinsic caspase pathways, preventing efficient antigen presentation.

Guzman E, Cubillos-Zapata C, Cottingham MG, Gilbert SC, Prentice H, Charleston B, Hope JC.

J Virol. 2012 May;86(10):5452-66. doi: 10.1128/JVI.00264-12. Epub 2012 Mar 14.

31.

Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin.

Hope JC, Guzman E, Cubillos-Zapata C, Stephens SA, Gilbert SC, Prentice H, Sopp P, Howard CJ, Charleston B.

Vaccine. 2012 Mar 16;30(13):2357-67. doi: 10.1016/j.vaccine.2012.01.036. Epub 2012 Jan 24.

PMID:
22281103
32.

Differential effects of viral vectors on migratory afferent lymph dendritic cells in vitro predict enhanced immunogenicity in vivo.

Cubillos-Zapata C, Guzman E, Turner A, Gilbert SC, Prentice H, Hope JC, Charleston B.

J Virol. 2011 Sep;85(18):9385-94. doi: 10.1128/JVI.05127-11. Epub 2011 Jul 13.

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