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Items: 1 to 50 of 180

1.

The Diagnostic and Clinical Utility of Autoantibodies in Systemic Vasculitis.

Csernok E.

Antibodies (Basel). 2019 May 1;8(2). pii: E31. doi: 10.3390/antib8020031. Review.

2.

Investigations in systemic vasculitis. The role of the laboratory.

Csernok E, Bossuyt X.

Best Pract Res Clin Rheumatol. 2018 Feb;32(1):52-62. doi: 10.1016/j.berh.2018.07.005. Epub 2018 Aug 16. Review.

PMID:
30526898
3.

The European Vasculitis Society 2016 Meeting Report.

Bajema IM, Bruijn JA, Casian A, Cid MC, Csernok E, van Daalen E, Harper L, Hauser T, Little MA, Luqmani RA, Mahr A, Ponte C, Salama A, Segelmark M, Suzuki K, Sznajd J, Teng YKO, Vaglio A, Westman K, Jayne D.

Kidney Int Rep. 2017 Sep 21;2(6):1018-1031. doi: 10.1016/j.ekir.2017.09.008. eCollection 2017 Nov.

4.

[ANCA-associated vasculitis: recent methodological advances for ANCA detection].

Csernok E.

Dtsch Med Wochenschr. 2018 Apr;143(7):499-502. doi: 10.1055/a-0542-3347. Epub 2018 Apr 3. German.

PMID:
29614541
5.

Anti-neutrophil cytoplasm antibodies (ANCA): Recent methodological advances-Lead to new consensus recommendations for ANCA detection.

Csernok E, Mahrhold J, Hellmich B.

J Immunol Methods. 2018 May;456:1-6. doi: 10.1016/j.jim.2018.01.007. Epub 2018 Jan 31. Review.

PMID:
29395165
6.

Position paper: Revised 2017 international consensus on testing of ANCAs in granulomatosis with polyangiitis and microscopic polyangiitis.

Bossuyt X, Cohen Tervaert JW, Arimura Y, Blockmans D, Flores-Suárez LF, Guillevin L, Hellmich B, Jayne D, Jennette JC, Kallenberg CGM, Moiseev S, Novikov P, Radice A, Savige JA, Sinico RA, Specks U, van Paassen P, Zhao MH, Rasmussen N, Damoiseaux J, Csernok E.

Nat Rev Rheumatol. 2017 Nov;13(11):683-692. doi: 10.1038/nrrheum.2017.140. Epub 2017 Sep 14. Review.

PMID:
28905856
7.

Individual values of antineutrophil cytoplasmic antibodies do not correspond between antigen-specific assays.

Rasmussen N, Damoiseaux J, Csernok E, Heegaard NHH, Hellmich B, Paassen PV, Baslund B, Vermeersch P, Blockmans D, Tervaert JC, Bossuyt X.

Clin Chem Lab Med. 2018 Jan 26;56(2):e39-e42. doi: 10.1515/cclm-2017-0362. No abstract available.

PMID:
28755530
8.

PR3-anti-neutrophil cytoplasmic antibodies (ANCA) in ulcerative colitis.

Mahler M, Damoiseaux J, Ballet V, Dillaerts D, Bentow C, Cohen Tervaert JW, Blockmans D, Boeckxstaens G, Aguilera-Lizarraga J, Csernok E, Vermeire S, Bossuyt X.

Clin Chem Lab Med. 2017 Nov 27;56(1):e27-e30. doi: 10.1515/cclm-2017-0346. No abstract available.

PMID:
28755529
9.

A multicentre study to improve clinical interpretation of proteinase-3 and myeloperoxidase anti-neutrophil cytoplasmic antibodies.

Bossuyt X, Rasmussen N, van Paassen P, Hellmich B, Baslund B, Vermeersch P, Blockmans D, Cohen Tervaert JW, Csernok E, Damoiseaux J.

Rheumatology (Oxford). 2017 Sep 1;56(9):1633. doi: 10.1093/rheumatology/kex266. No abstract available.

PMID:
28641391
10.

A multicentre study to improve clinical interpretation of proteinase-3 and myeloperoxidase anti-neutrophil cytoplasmic antibodies.

Bossuyt X, Rasmussen N, van Paassen P, Hellmich B, Baslund B, Vermeersch P, Blockmans D, Cohen Tervaert JW, Csernok E, Damoiseaux J.

Rheumatology (Oxford). 2017 Sep 1;56(9):1533-1541. doi: 10.1093/rheumatology/kex170. Erratum in: Rheumatology (Oxford). 2017 Sep 1;56(9):1633.

PMID:
28541581
11.

Neutrophil Extracellular Traps Contain Selected Antigens of Anti-Neutrophil Cytoplasmic Antibodies.

Panda R, Krieger T, Hopf L, Renné T, Haag F, Röber N, Conrad K, Csernok E, Fuchs TA.

Front Immunol. 2017 Apr 13;8:439. doi: 10.3389/fimmu.2017.00439. eCollection 2017.

12.

Immune stimulatory effects of neutrophil extracellular traps in granulomatosis with polyangiitis.

Lange C, Csernok E, Moosig F, Holle JU.

Clin Exp Rheumatol. 2017 Mar-Apr;35 Suppl 103(1):33-39. Epub 2017 Mar 8.

PMID:
28281454
13.

Antineutrophil cytoplasmic antibodies: reporting and diagnostic strategies.

Damoiseaux J, Csernok E, Rasmussen N, Cohen Tervaert JW, Bossuyt X.

Ann Rheum Dis. 2017 Oct;76(10):e39. doi: 10.1136/annrheumdis-2017-211171. Epub 2017 Mar 8. No abstract available.

PMID:
28274911
14.

[Paradigm shift in ANCA diagnostics : New international consensus recommendations].

Csernok E, Kempiners N, Hellmich B.

Z Rheumatol. 2017 Mar;76(2):143-148. doi: 10.1007/s00393-016-0240-x. Review. German.

PMID:
28058500
15.

Antineutrophil cytoplasmic antibodies: appropriate use and interpretation.

Damoiseaux J, Csernok E, Rasmussen N, Cohen Tervaert JW, Bossuyt X.

Ann Rheum Dis. 2017 Aug;76(8):e24. doi: 10.1136/annrheumdis-2016-210908. Epub 2017 Jan 2. No abstract available.

PMID:
28043997
16.

Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations.

Langley GR, Adcock IM, Busquet F, Crofton KM, Csernok E, Giese C, Heinonen T, Herrmann K, Hofmann-Apitius M, Landesmann B, Marshall LJ, McIvor E, Muotri AR, Noor F, Schutte K, Seidle T, van de Stolpe A, Van Esch H, Willett C, Woszczek G.

Drug Discov Today. 2017 Feb;22(2):327-339. doi: 10.1016/j.drudis.2016.10.011. Epub 2016 Oct 29. Review.

17.

Detection of antineutrophil cytoplasmic antibodies (ANCAs): a multicentre European Vasculitis Study Group (EUVAS) evaluation of the value of indirect immunofluorescence (IIF) versus antigen-specific immunoassays.

Damoiseaux J, Csernok E, Rasmussen N, Moosig F, van Paassen P, Baslund B, Vermeersch P, Blockmans D, Cohen Tervaert JW, Bossuyt X.

Ann Rheum Dis. 2017 Apr;76(4):647-653. doi: 10.1136/annrheumdis-2016-209507. Epub 2016 Aug 1.

PMID:
27481830
18.

Evaluation of automated multi-parametric indirect immunofluorescence assays to detect anti-neutrophil cytoplasmic antibodies (ANCA) in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).

Csernok E, Damoiseaux J, Rasmussen N, Hellmich B, van Paassen P, Vermeersch P, Blockmans D, Cohen Tervaert JW, Bossuyt X.

Autoimmun Rev. 2016 Jul;15(7):736-41. doi: 10.1016/j.autrev.2016.03.010. Epub 2016 Mar 9. Review.

PMID:
26970486
19.

Diagnostic Value of Procalcitonin in ANCA-Associated Vasculitis (AAV) to Differentiate Between Disease Activity, Infection and Drug Hypersensitivity.

Herrmann K, Schinke S, Csernok E, Moosig F, Holle JU.

Open Rheumatol J. 2015 Oct 9;9:71-6. doi: 10.2174/1874312901409010071. eCollection 2015.

20.

Correction: Simultaneous Automated Screening and Confirmatory Testing for Vasculitis-Specific ANCA.

Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D.

PLoS One. 2015 May 13;10(5):e0127933. doi: 10.1371/journal.pone.0127933. eCollection 2015. No abstract available.

21.

Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis: challenges and solutions 2014.

Schönermarck U, Csernok E, Gross WL.

Nephrol Dial Transplant. 2015 Apr;30 Suppl 1:i46-52. doi: 10.1093/ndt/gfu398. Epub 2014 Dec 23. Review.

PMID:
25540095
22.

Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.

Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D.

PLoS One. 2014 Sep 16;9(9):e107743. doi: 10.1371/journal.pone.0107743. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0120626. PLoS One. 2015;10(5):e0127933.

23.

Current and emerging techniques for ANCA detection in vasculitis.

Csernok E, Moosig F.

Nat Rev Rheumatol. 2014 Aug;10(8):494-501. doi: 10.1038/nrrheum.2014.78. Epub 2014 Jun 3. Review.

PMID:
24890776
24.

Co-occurrence of autoantibodies in healthy blood donors.

Prüßmann J, Prüßmann W, Recke A, Rentzsch K, Juhl D, Henschler R, Müller S, Lamprecht P, Schmidt E, Csernok E, Görg S, Stöcker W, Zillikens D, Ibrahim SM, Ludwig RJ.

Exp Dermatol. 2014 Jul;23(7):519-21. doi: 10.1111/exd.12445.

PMID:
24816528
25.

Deimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity.

Dwivedi N, Neeli I, Schall N, Wan H, Desiderio DM, Csernok E, Thompson PR, Dali H, Briand JP, Muller S, Radic M.

FASEB J. 2014 Jul;28(7):2840-51. doi: 10.1096/fj.13-247254. Epub 2014 Mar 26.

26.

Plasma cells within granulomatous inflammation display signs pointing to autoreactivity and destruction in granulomatosis with polyangiitis.

Mueller A, Brieske C, Schinke S, Csernok E, Gross WL, Hasselbacher K, Voswinkel J, Holl-Ulrich K.

Arthritis Res Ther. 2014 Feb 20;16(1):R55. doi: 10.1186/ar4490.

27.

Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener's).

Csernok E, Gross WL.

Expert Rev Clin Immunol. 2013 Jul;9(7):641-8. doi: 10.1586/1744666X.2013.811052. Review.

PMID:
23899234
28.

PR3-ANCA: a promising biomarker for ulcerative colitis with extensive disease.

Mahler M, Bogdanos DP, Pavlidis P, Fritzler MJ, Csernok E, Damoiseaux J, Bentow C, Shums Z, Forbes A, Norman GL.

Clin Chim Acta. 2013 Sep 23;424:267-73. doi: 10.1016/j.cca.2013.06.005. Epub 2013 Jun 24.

PMID:
23806819
29.

Toll-like receptor TLR2 and TLR9 ligation triggers neutrophil activation in granulomatosis with polyangiitis.

Holle JU, Windmöller M, Lange C, Gross WL, Herlyn K, Csernok E.

Rheumatology (Oxford). 2013 Jul;52(7):1183-9. doi: 10.1093/rheumatology/kes415. Epub 2013 Feb 12.

PMID:
23407387
30.

Getting rid of MPO-ANCA: a matter of disease subtype.

Bremer JP, Csernok E, Holle J, Gross WL, Moosig F.

Rheumatology (Oxford). 2013 Apr;52(4):752-4. doi: 10.1093/rheumatology/kes412. Epub 2013 Jan 23. No abstract available.

PMID:
23345506
31.

Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis.

Knütter I, Hiemann R, Brumma T, Büttner T, Großmann K, Cusini M, Pregnolato F, Borghi MO, Anderer U, Conrad K, Reinhold D, Roggenbuck D, Csernok E.

Arthritis Res Ther. 2012 Dec 14;14(6):R271. doi: 10.1186/ar4119.

32.

ANCA testing: the current stage and perspectives.

Csernok E.

Clin Exp Nephrol. 2013 Oct;17(5):615-618. doi: 10.1007/s10157-012-0735-y. Epub 2012 Nov 23. Review.

PMID:
23180043
33.

Progranulin antibodies in autoimmune diseases.

Thurner L, Preuss KD, Fadle N, Regitz E, Klemm P, Zaks M, Kemele M, Hasenfus A, Csernok E, Gross WL, Pasquali JL, Martin T, Bohle RM, Pfreundschuh M.

J Autoimmun. 2013 May;42:29-38. doi: 10.1016/j.jaut.2012.10.003. Epub 2012 Nov 11.

PMID:
23149338
34.

Comparative analysis of different commercial ELISA systems for the detection of anti-neutrophil cytoplasm antibodies in ANCA-associated vasculitides.

Holle JU, Herrmann K, Gross WL, Csernok E.

Clin Exp Rheumatol. 2012 Jan-Feb;30(1 Suppl 70):S66-9. Epub 2012 May 10.

PMID:
22512915
35.

Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.

Kesel N, Köhler D, Herich L, Laudien M, Holl-Ulrich K, Jüngel A, Neidhart M, Gay S, Gay RE, Csernok E, Lamprecht P, Gross WL, Schumacher U, Ullrich S.

Am J Pathol. 2012 May;180(5):2144-55. doi: 10.1016/j.ajpath.2012.01.021. Epub 2012 Mar 23.

PMID:
22449947
36.

Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps.

Dwivedi N, Upadhyay J, Neeli I, Khan S, Pattanaik D, Myers L, Kirou KA, Hellmich B, Knuckley B, Thompson PR, Crow MK, Mikuls TR, Csernok E, Radic M.

Arthritis Rheum. 2012 Apr;64(4):982-92. doi: 10.1002/art.33432. Epub 2011 Oct 27.

37.

Correlation of serum level of high mobility group box 1 with the burden of granulomatous inflammation in granulomatosis with polyangiitis (Wegener's).

Henes FO, Chen Y, Bley TA, Fabel M, Both M, Herrmann K, Csernok E, Gross WL, Moosig F.

Ann Rheum Dis. 2011 Nov;70(11):1926-9. doi: 10.1136/ard.2010.146456. Epub 2011 Jul 16.

PMID:
21765168
38.

Distinct proteinase 3-induced cytokine patterns in Wegener´s granulomatosis, Churg-Strauss syndrome, and healthy controls.

Fagin U, Csernok E, Müller A, Pitann S, Fazio J, Krause K, Bremer P, Wipfler-Freissmuth E, Moosig F, Gross WL, Lamprecht P.

Clin Exp Rheumatol. 2011 Jan-Feb;29(1 Suppl 64):S57-62. Epub 2011 May 11.

PMID:
21470489
39.

Use of highly sensitive C-reactive protein for followup of Wegener's granulomatosis.

Kälsch AI, Csernok E, Münch D, Birck R, Yard BA, Gross W, Kälsch T, Schmitt WH.

J Rheumatol. 2010 Nov;37(11):2319-25. doi: 10.3899/jrheum.100302. Epub 2010 Aug 17.

PMID:
20716656
40.

Serum HMGB1 levels are increased in active Wegener's granulomatosis and differentiate between active forms of ANCA-associated vasculitis.

Wibisono D, Csernok E, Lamprecht P, Holle JU, Gross WL, Moosig F.

Ann Rheum Dis. 2010 Oct;69(10):1888-9. doi: 10.1136/ard.2009.119172. Epub 2010 Jun 11. No abstract available.

PMID:
20542962
41.

Lower numbers of FoxP3 and CCR4 co-expressing cells in an elevated subpopulation of CD4+CD25high regulatory T cells from Wegener's granulomatosis.

Klapa S, Mueller A, Csernok E, Fagin U, Klenerman P, Holl-Ulrich K, Gross WL, Lamprecht P.

Clin Exp Rheumatol. 2010 Jan-Feb;28(1 Suppl 57):72-80.

PMID:
20412707
42.

The role of proteinase 3 (PR3) and the protease-activated receptor-2 (PAR-2) pathway in dendritic cell (DC) maturation of human-DC-like monocytes and murine DC.

Jiang B, Grage-Griebenow E, Csernok E, Butherus K, Ehlers S, Gross WL, Holle JU.

Clin Exp Rheumatol. 2010 Jan-Feb;28(1 Suppl 57):56-61.

PMID:
20412704
43.

Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.

Laudien M, Gadola SD, Podschun R, Hedderich J, Paulsen J, Reinhold-Keller E, Csernok E, Ambrosch P, Hellmich B, Moosig F, Gross WL, Sahly H, Lamprecht P.

Clin Exp Rheumatol. 2010 Jan-Feb;28(1 Suppl 57):51-5.

PMID:
20412703
44.

Membrane proteinase 3 (mPR3) expression on neutrophils is not increased in localized Wegener's granulomatosis (WG) and Churg-Strauss syndrome (CSS).

Holle JU, Wu QJ, Moosig F, Gross WL, Csernok E.

Clin Exp Rheumatol. 2010 Jan-Feb;28(1 Suppl 57):46-50.

PMID:
20412702
45.

Interferon-alpha for maintenance of remission in Churg-Strauss syndrome: a long-term observational study.

Metzler C, Csernok E, Gross WL, Hellmich B.

Clin Exp Rheumatol. 2010 Jan-Feb;28(1 Suppl 57):24-30.

PMID:
20412698
46.

Prospective long-term follow-up of patients with localised Wegener's granulomatosis: does it occur as persistent disease stage?

Holle JU, Gross WL, Holl-Ulrich K, Ambrosch P, Noelle B, Both M, Csernok E, Moosig F, Schinke S, Reinhold-Keller E.

Ann Rheum Dis. 2010 Nov;69(11):1934-9. doi: 10.1136/ard.2010.130203. Epub 2010 May 28.

PMID:
20511614
47.

Twenty-eight years with antineutrophil cytoplasmic antibodies (ANCA): how to test for ANCA - evidence-based immunology?

Csernok E, Holle JU.

Auto Immun Highlights. 2010 Jul 10;1(1):39-43. doi: 10.1007/s13317-010-0007-3. eCollection 2010 May. Review.

48.

Genetic predisposition (NLRP3 V198M mutation) for IL-1-mediated inflammation in a patient with Schnitzler syndrome.

Loock J, Lamprecht P, Timmann C, Mrowietz U, Csernok E, Gross WL.

J Allergy Clin Immunol. 2010 Feb;125(2):500-2. doi: 10.1016/j.jaci.2009.10.066. No abstract available.

PMID:
20159265
49.

Are anti-cyclic citrullinated peptide autoantibodies seromarkers for rheumatoid vasculitis in a cohort of patients with systemic vasculitis?

Laskari K, Ahmadi-Simab K, Lamken M, Csernok E, Gross WL, Hellmich B.

Ann Rheum Dis. 2010 Feb;69(2):469-71. doi: 10.1136/ard.2009.110411. No abstract available. Erratum in: Ann Rheum Dis. 2010 May;69(5):812. Laskaria, K [corrected to Laskari, K].

PMID:
20107034
50.

Clinical evaluation of hsPR3-ANCA ELISA for detection of antineutrophil cytoplasmatic antibodies directed against proteinase 3.

Holle JU, Csernok E, Fredenhagen G, Backes M, Bremer JP, Gross WL.

Ann Rheum Dis. 2010 Feb;69(2):468-9. doi: 10.1136/ard.2009.109868. No abstract available.

PMID:
20107033

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