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Best matches for Csanády L[au]:

Molecular Structure of the Human CFTR Ion Channel. Liu F et al. Cell. (2017)

A new target for G protein signaling. Csanády L et al. Elife. (2017)

Asymmetry of movements in CFTR's two ATP sites during pore opening serves their distinct functions. Sorum B et al. Elife. (2017)

Search results

Items: 41

1.

Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.

Zhang Z, Tóth B, Szollosi A, Chen J, Csanády L.

Elife. 2018 May 10;7. pii: e36409. doi: 10.7554/eLife.36409.

2.

Ion channels as targets to treat cystic fibrosis lung disease.

Martin SL, Saint-Criq V, Hwang TC, Csanády L.

J Cyst Fibros. 2018 Mar;17(2S):S22-S27. doi: 10.1016/j.jcf.2017.10.006. Epub 2017 Nov 6. Review.

PMID:
29102290
3.

Asymmetry of movements in CFTR's two ATP sites during pore opening serves their distinct functions.

Sorum B, Töröcsik B, Csanády L.

Elife. 2017 Sep 25;6. pii: e29013. doi: 10.7554/eLife.29013.

4.

A new target for G protein signaling.

Csanády L.

Elife. 2017 Sep 11;6. pii: e31106. doi: 10.7554/eLife.31106.

5.

Molecular Structure of the Human CFTR Ion Channel.

Liu F, Zhang Z, Csanády L, Gadsby DC, Chen J.

Cell. 2017 Mar 23;169(1):85-95.e8. doi: 10.1016/j.cell.2017.02.024.

6.

CFTR gating: Invisible transitions made visible.

Csanády L.

J Gen Physiol. 2017 Apr 3;149(4):413-416. doi: 10.1085/jgp.201711777. Epub 2017 Mar 6. No abstract available.

7.

The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity.

Iordanov I, Mihályi C, Tóth B, Csanády L.

Elife. 2016 Jul 6;5. pii: e17600. doi: 10.7554/eLife.17600.

8.

Obligate coupling of CFTR pore opening to tight nucleotide-binding domain dimerization.

Mihályi C, Töröcsik B, Csanády L.

Elife. 2016 Jun 21;5. pii: e18164. doi: 10.7554/eLife.18164.

9.

A single active catalytic site is sufficient to promote transport in P-glycoprotein.

Bársony O, Szalóki G, Türk D, Tarapcsák S, Gutay-Tóth Z, Bacsó Z, Holb IJ, Székvölgyi L, Szabó G, Csanády L, Szakács G, Goda K.

Sci Rep. 2016 Apr 27;6:24810. doi: 10.1038/srep24810.

10.

Timing of CFTR pore opening and structure of its transition state.

Sorum B, Czégé D, Csanády L.

Cell. 2015 Oct 22;163(3):724-33. doi: 10.1016/j.cell.2015.09.052. Epub 2015 Oct 22.

11.

Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate.

Tóth B, Iordanov I, Csanády L.

J Gen Physiol. 2015 May;145(5):419-30. doi: 10.1085/jgp.201511377.

12.

Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating.

Tóth B, Iordanov I, Csanády L.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16949-54. doi: 10.1073/pnas.1412449111. Epub 2014 Nov 10.

13.

Structure-activity analysis of a CFTR channel potentiator: Distinct molecular parts underlie dual gating effects.

Csanády L, Töröcsik B.

J Gen Physiol. 2014 Oct;144(4):321-36. doi: 10.1085/jgp.201411246.

14.

Catalyst-like modulation of transition states for CFTR channel opening and closing: new stimulation strategy exploits nonequilibrium gating.

Csanády L, Töröcsik B.

J Gen Physiol. 2014 Feb;143(2):269-87. doi: 10.1085/jgp.201311089. Epub 2014 Jan 13.

15.

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR.

Csanády L, Mihályi C, Szollosi A, Töröcsik B, Vergani P.

J Gen Physiol. 2013 Jul;142(1):61-73. doi: 10.1085/jgp.201210954. Epub 2013 Jun 10.

16.

Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.

Tóth B, Csanády L.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13440-5. doi: 10.1073/pnas.1204702109. Epub 2012 Jul 30.

17.

Electrophysiological, biochemical, and bioinformatic methods for studying CFTR channel gating and its regulation.

Csanády L, Vergani P, Gulyás-Kovács A, Gadsby DC.

Methods Mol Biol. 2011;741:443-69. doi: 10.1007/978-1-61779-117-8_28.

PMID:
21594801
18.

Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating.

Szollosi A, Muallem DR, Csanády L, Vergani P.

J Gen Physiol. 2011 Jun;137(6):549-62. doi: 10.1085/jgp.201110608. Epub 2011 May 16.

19.

Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2.

Szollosi A, Vergani P, Csanády L.

J Gen Physiol. 2010 Oct;136(4):407-23. doi: 10.1085/jgp.201010434.

20.

Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane.

Homolya L, Orbán TI, Csanády L, Sarkadi B.

Biochim Biophys Acta. 2011 Jan;1808(1):154-63. doi: 10.1016/j.bbamem.2010.07.031. Epub 2010 Aug 4.

21.

Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.

Tóth B, Csanády L.

J Biol Chem. 2010 Sep 24;285(39):30091-102. doi: 10.1074/jbc.M109.066464. Epub 2010 Jul 22.

22.

Permeating proton found guilty in compromising TRPM2 channel activity.

Csanády L.

J Physiol. 2010 May 15;588(Pt 10):1661-2. doi: 10.1113/jphysiol.2010.190223. No abstract available.

23.

Degenerate ABC composite site is stably glued together by trapped ATP.

Csanády L.

J Gen Physiol. 2010 May;135(5):395-8. doi: 10.1085/jgp.201010443. No abstract available.

24.

Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations.

Csanády L, Vergani P, Gadsby DC.

Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1241-6. doi: 10.1073/pnas.0911061107. Epub 2009 Dec 4.

25.
26.

A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT.

Chinopoulos C, Vajda S, Csanády L, Mándi M, Mathe K, Adam-Vizi V.

Biophys J. 2009 Mar 18;96(6):2490-504. doi: 10.1016/j.bpj.2008.12.3915.

27.

Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate.

Csanády L, Törocsik B.

J Gen Physiol. 2009 Feb;133(2):189-203. doi: 10.1085/jgp.200810109.

28.

The twain shall meet: channels, transporters and things between. Meeting on Membrane Transport in Flux: the Ambiguous Interface Between Channels and Pumps.

Csanády L, Mindell JA.

EMBO Rep. 2008 Oct;9(10):960-5. doi: 10.1038/embor.2008.172. Epub 2008 Sep 5. Review. No abstract available.

29.

Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition.

Chan KW, Wheeler A, Csanády L.

J Gen Physiol. 2008 Jan;131(1):43-58. Epub 2007 Dec 17.

30.

Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle.

Csanády L, Nairn AC, Gadsby DC.

J Gen Physiol. 2006 Nov;128(5):523-33. Epub 2006 Oct 16.

31.
32.

The ABC protein turned chloride channel whose failure causes cystic fibrosis.

Gadsby DC, Vergani P, Csanády L.

Nature. 2006 Mar 23;440(7083):477-83. Review.

33.
34.

Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

Csanády L, Seto-Young D, Chan KW, Cenciarelli C, Angel BB, Qin J, McLachlin DT, Krutchinsky AN, Chait BT, Nairn AC, Gadsby DC.

J Gen Physiol. 2005 Feb;125(2):171-86. Epub 2005 Jan 18.

35.

Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain.

Csanády L, Chan KW, Nairn AC, Gadsby DC.

J Gen Physiol. 2005 Jan;125(1):43-55. Epub 2004 Dec 13.

38.

Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains.

Csanády L, Chan KW, Seto-Young D, Kopsco DC, Nairn AC, Gadsby DC.

J Gen Physiol. 2000 Sep;116(3):477-500.

39.
41.

CFTR channel gating: incremental progress in irreversible steps.

Csanády L, Gadsby DC.

J Gen Physiol. 1999 Jul;114(1):49-53. Review. No abstract available.

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