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Items: 14


Estrogen Receptor Beta-Mediated Modulation of Lung Cancer Cell Proliferation by 27-Hydroxycholesterol.

Hiramitsu S, Ishikawa T, Lee WR, Khan T, Crumbley C, Khwaja N, Zamanian F, Asghari A, Sen M, Zhang Y, Hawse JR, Minna JD, Umetani M.

Front Endocrinol (Lausanne). 2018 Aug 23;9:470. doi: 10.3389/fendo.2018.00470. eCollection 2018.


Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.

Gong X, Yi J, Carmon KS, Crumbley CA, Xiong W, Thomas A, Fan X, Guo S, An Z, Chang JT, Liu QJ.

Oncogene. 2015 Sep 3;34(36):4692-701. doi: 10.1038/onc.2014.417. Epub 2014 Dec 22.


Nuclear receptors and their selective pharmacologic modulators.

Burris TP, Solt LA, Wang Y, Crumbley C, Banerjee S, Griffett K, Lundasen T, Hughes T, Kojetin DJ.

Pharmacol Rev. 2013 Mar 1;65(2):710-78. doi: 10.1124/pr.112.006833. Print 2013 Apr. Review.


The sustainability solutions agenda.

Sarewitz D, Clapp R, Crumbley C, Kriebel D, Tickner J.

New Solut. 2012;22(2):139-51. doi: 10.2190/NS.22.2.c.


Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor α (RORα).

Crumbley C, Wang Y, Banerjee S, Burris TP.

PLoS One. 2012;7(4):e33804. doi: 10.1371/journal.pone.0033804. Epub 2012 Apr 2.


Direct regulation of CLOCK expression by REV-ERB.

Crumbley C, Burris TP.

PLoS One. 2011 Mar 29;6(3):e17290. doi: 10.1371/journal.pone.0017290.


Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene.

Crumbley C, Wang Y, Kojetin DJ, Burris TP.

J Biol Chem. 2010 Nov 12;285(46):35386-92. doi: 10.1074/jbc.M110.129288. Epub 2010 Sep 3.


Regulation of adipogenesis by natural and synthetic REV-ERB ligands.

Kumar N, Solt LA, Wang Y, Rogers PM, Bhattacharyya G, Kamenecka TM, Stayrook KR, Crumbley C, Floyd ZE, Gimble JM, Griffin PR, Burris TP.

Endocrinology. 2010 Jul;151(7):3015-25. doi: 10.1210/en.2009-0800. Epub 2010 Apr 28.


A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol).

Wang Y, Kumar N, Crumbley C, Griffin PR, Burris TP.

Biochim Biophys Acta. 2010 Aug;1801(8):917-23. doi: 10.1016/j.bbalip.2010.02.012. Epub 2010 Mar 6.


Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands.

Wang Y, Kumar N, Solt LA, Richardson TI, Helvering LM, Crumbley C, Garcia-Ordonez RD, Stayrook KR, Zhang X, Novick S, Chalmers MJ, Griffin PR, Burris TP.

J Biol Chem. 2010 Feb 12;285(7):5013-25. doi: 10.1074/jbc.M109.080614. Epub 2009 Dec 4.


The N-terminal nuclear localization sequences of liver X receptors alpha and beta bind to importin alpha and are essential for both nuclear import and transactivating functions.

Miller A, Crumbley C, Prüfer K.

Int J Biochem Cell Biol. 2009 Apr;41(4):834-43. doi: 10.1016/j.biocel.2008.08.016. Epub 2008 Aug 19.


The Louisville Charter: The NGO blueprint for new chemicals policy.

Geiser K, Rossi M, Crumbley C.

New Solut. 2007;17(3):167-71. No abstract available.


The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation.

Dass NB, John AK, Bassil AK, Crumbley CW, Shehee WR, Maurio FP, Moore GB, Taylor CM, Sanger GJ.

Neurogastroenterol Motil. 2007 Jan;19(1):66-74.


5-Hydroxytryptamine (5HT) receptors in the heart valves of cynomolgus monkeys and Sprague-Dawley rats.

Elangbam CS, Lightfoot RM, Yoon LW, Creech DR, Geske RS, Crumbley CW, Gates LD, Wall HG.

J Histochem Cytochem. 2005 May;53(5):671-7.


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