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Items: 1 to 50 of 61

1.

Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome.

Voorhies AA, Mark Ott C, Mehta S, Pierson DL, Crucian BE, Feiveson A, Oubre CM, Torralba M, Moncera K, Zhang Y, Zurek E, Lorenzi HA.

Sci Rep. 2019 Jul 9;9(1):9911. doi: 10.1038/s41598-019-46303-8.

2.

Simian Varicella Virus DNA in Saliva and Buccal Cells After Experimental Acute Infection in Rhesus Macaques.

Traina-Dorge V, Mehta S, Rooney B, Crucian B, Doyle-Meyers L, Das A, Coleman C, Nagel M, Mahalingam R.

Front Microbiol. 2019 May 9;10:1009. doi: 10.3389/fmicb.2019.01009. eCollection 2019.

3.

Effects of microgravity and other space stressors in immunosuppression and viral reactivation with potential nervous system involvement.

Mann V, Sundaresan A, Mehta SK, Crucian B, Doursout MF, Devakottai S.

Neurol India. 2019 May-Jun;67(Supplement):S198-S203. doi: 10.4103/0028-3886.259125. Review.

4.

Immune function testing in sepsis patients receiving sodium selenite.

Guo A, Srinath J, Feuerecker M, Crucian B, Briegel J, Boulesteix AL, Kaufmann I, Choukèr A.

J Crit Care. 2019 Aug;52:208-212. doi: 10.1016/j.jcrc.2019.05.001. Epub 2019 May 4.

PMID:
31102938
5.

Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation Exposure.

Moreno-Villanueva M, Zhang Y, Feiveson A, Mistretta B, Pan Y, Chatterjee S, Wu W, Clanton R, Nelman-Gonzalez M, Krieger S, Gunaratne P, Crucian B, Wu H.

Int J Mol Sci. 2019 May 10;20(9). pii: E2316. doi: 10.3390/ijms20092316.

6.

Sex differences in stress and immune responses during confinement in Antarctica.

Strewe C, Moser D, Buchheim JI, Gunga HC, Stahn A, Crucian BE, Fiedel B, Bauer H, Gössmann-Lang P, Thieme D, Kohlberg E, Choukèr A, Feuerecker M.

Biol Sex Differ. 2019 Apr 16;10(1):20. doi: 10.1186/s13293-019-0231-0.

7.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
8.

Neurophysiological, neuropsychological, and cognitive effects of 30 days of isolation.

Weber J, Javelle F, Klein T, Foitschik T, Crucian B, Schneider S, Abeln V.

Exp Brain Res. 2019 Jun;237(6):1563-1573. doi: 10.1007/s00221-019-05531-0. Epub 2019 Mar 29.

PMID:
30927043
9.

Herpes Virus Reactivation in Astronauts During Spaceflight and Its Application on Earth.

Rooney BV, Crucian BE, Pierson DL, Laudenslager ML, Mehta SK.

Front Microbiol. 2019 Feb 7;10:16. doi: 10.3389/fmicb.2019.00016. eCollection 2019. Review.

10.

B cell homeostasis is maintained during long-duration spaceflight.

Spielmann G, Agha N, Kunz H, Simpson RJ, Crucian B, Mehta S, Laughlin M, Campbell J.

J Appl Physiol (1985). 2019 Feb 1;126(2):469-476. doi: 10.1152/japplphysiol.00789.2018. Epub 2018 Nov 29.

PMID:
30496712
11.

Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells.

Moreno-Villanueva M, Feiveson AH, Krieger S, Kay Brinda A, von Scheven G, Bürkle A, Crucian B, Wu H.

Int J Mol Sci. 2018 Nov 21;19(11). pii: E3689. doi: 10.3390/ijms19113689.

12.

NK cell function is impaired during long-duration spaceflight.

Bigley AB, Agha NH, Baker FL, Spielmann G, Kunz HE, Mylabathula PL, Rooney BV, Laughlin MS, Mehta SK, Pierson DL, Crucian BE, Simpson RJ.

J Appl Physiol (1985). 2019 Apr 1;126(4):842-853. doi: 10.1152/japplphysiol.00761.2018. Epub 2018 Nov 1.

PMID:
30382809
13.

Reactivation of Latent Epstein-Barr Virus: A Comparison after Exposure to Gamma, Proton, Carbon, and Iron Radiation.

Mehta SK, Bloom DC, Plante I, Stowe R, Feiveson AH, Renner A, Dhummakupt A, Markan D, Zhang Y, Wu H, Scoles B, Cohen JI, Crucian B, Pierson DL.

Int J Mol Sci. 2018 Sep 28;19(10). pii: E2961. doi: 10.3390/ijms19102961.

14.

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.

Crucian BE, Choukèr A, Simpson RJ, Mehta S, Marshall G, Smith SM, Zwart SR, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Lorenzi H, Buchheim JI, Makedonas G, Ginsburg GS, Ott CM, Pierson DL, Krieger SS, Baecker N, Sams C.

Front Immunol. 2018 Jun 28;9:1437. doi: 10.3389/fimmu.2018.01437. eCollection 2018. Review.

15.

Immune sensitization during 1 year in the Antarctic high-altitude Concordia Environment.

Feuerecker M, Crucian BE, Quintens R, Buchheim JI, Salam AP, Rybka A, Moreels M, Strewe C, Stowe R, Mehta S, Schelling G, Thiel M, Baatout S, Sams C, Choukèr A.

Allergy. 2019 Jan;74(1):64-77. doi: 10.1111/all.13545. Epub 2018 Nov 20.

PMID:
29978486
16.

Early immune anergy towards recall antigens and mitogens in patients at onset of septic shock.

Feuerecker M, Sudhoff L, Crucian B, Pagel JI, Sams C, Strewe C, Guo A, Schelling G, Briegel J, Kaufmann I, Choukèr A.

Sci Rep. 2018 Jan 29;8(1):1754. doi: 10.1038/s41598-018-19976-w.

17.

Increased core body temperature in astronauts during long-duration space missions.

Stahn AC, Werner A, Opatz O, Maggioni MA, Steinach M, von Ahlefeld VW, Moore A, Crucian BE, Smith SM, Zwart SR, Schlabs T, Mendt S, Trippel T, Koralewski E, Koch J, Choukèr A, Reitz G, Shang P, Röcker L, Kirsch KA, Gunga HC.

Sci Rep. 2017 Nov 23;7(1):16180. doi: 10.1038/s41598-017-15560-w.

18.

Alterations in hematologic indices during long-duration spaceflight.

Kunz H, Quiriarte H, Simpson RJ, Ploutz-Snyder R, McMonigal K, Sams C, Crucian B.

BMC Hematol. 2017 Sep 8;17:12. doi: 10.1186/s12878-017-0083-y. eCollection 2017.

19.

Towards human exploration of space: The THESEUS review series on immunology research priorities.

Frippiat JP, Crucian BE, de Quervain DJ, Grimm D, Montano N, Praun S, Roozendaal B, Schelling G, Thiel M, Ullrich O, Choukèr A.

NPJ Microgravity. 2016 Dec 1;2:16040. doi: 10.1038/npjmgrav.2016.40. eCollection 2016. Review.

20.

Evaluation of techniques for performing cellular isolation and preservation during microgravity conditions.

Rizzardi LF, Kunz H, Rubins K, Chouker A, Quiriarte H, Sams C, Crucian BE, Feinberg AP.

NPJ Microgravity. 2016 Jul 14;2:16025. doi: 10.1038/npjmgrav.2016.25. eCollection 2016.

21.

Latent virus reactivation in astronauts on the international space station.

Mehta SK, Laudenslager ML, Stowe RP, Crucian BE, Feiveson AH, Sams CF, Pierson DL.

NPJ Microgravity. 2017 Apr 12;3:11. doi: 10.1038/s41526-017-0015-y. eCollection 2017.

22.

Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns.

Barrila J, Yang J, Crabbé A, Sarker SF, Liu Y, Ott CM, Nelman-Gonzalez MA, Clemett SJ, Nydam SD, Forsyth RJ, Davis RR, Crucian BE, Quiriarte H, Roland KL, Brenneman K, Sams C, Loscher C, Nickerson CA.

NPJ Microgravity. 2017 Feb 28;3:10. doi: 10.1038/s41526-017-0011-2. eCollection 2017.

23.

Localization of VZV in saliva of zoster patients.

Mehta SK, Nelman-Gonzalez M, Tyring SK, Tong Y, Beitman A, Crucian BE, Renner AN, Pierson DL.

J Med Virol. 2017 Sep;89(9):1686-1689. doi: 10.1002/jmv.24807. Epub 2017 May 2.

PMID:
28295404
24.

Incidence of clinical symptoms during long-duration orbital spaceflight.

Crucian B, Babiak-Vazquez A, Johnston S, Pierson DL, Ott CM, Sams C.

Int J Gen Med. 2016 Nov 3;9:383-391. eCollection 2016.

25.

Decreases in thymopoiesis of astronauts returning from space flight.

Benjamin CL, Stowe RP, St John L, Sams CF, Mehta SK, Crucian BE, Pierson DL, Komanduri KV.

JCI Insight. 2016 Aug 4;1(12):e88787. doi: 10.1172/jci.insight.88787.

26.

A case of persistent skin rash and rhinitis with immune system dysregulation onboard the International Space Station.

Crucian B, Johnston S, Mehta S, Stowe R, Uchakin P, Quiriarte H, Pierson D, Laudenslager ML, Sams C.

J Allergy Clin Immunol Pract. 2016 Jul-Aug;4(4):759-762.e8. doi: 10.1016/j.jaip.2015.12.021. Epub 2016 Mar 29. No abstract available.

PMID:
27036643
27.

Alterations in adaptive immunity persist during long-duration spaceflight.

Crucian B, Stowe RP, Mehta S, Quiriarte H, Pierson D, Sams C.

NPJ Microgravity. 2015 Sep 3;1:15013. doi: 10.1038/npjmgrav.2015.13. eCollection 2015.

28.

Hyperbaric hyperoxia alters innate immune functional properties during NASA Extreme Environment Mission Operation (NEEMO).

Strewe C, Crucian BE, Sams CF, Feuerecker B, Stowe RP, Choukèr A, Feuerecker M.

Brain Behav Immun. 2015 Nov;50:52-57. doi: 10.1016/j.bbi.2015.06.017. Epub 2015 Jun 25.

PMID:
26116982
29.

Post-Spaceflight (STS-135) Mouse Splenocytes Demonstrate Altered Activation Properties and Surface Molecule Expression.

Hwang SA, Crucian B, Sams C, Actor JK.

PLoS One. 2015 May 13;10(5):e0124380. doi: 10.1371/journal.pone.0124380. eCollection 2015.

30.

Effects of sex and gender on adaptation to space: immune system.

Kennedy AR, Crucian B, Huff JL, Klein SL, Morens D, Murasko D, Nickerson CA, Sonnenfeld G.

J Womens Health (Larchmt). 2014 Nov;23(11):956-8. doi: 10.1089/jwh.2014.4913. Review.

31.

Early adaption to the antarctic environment at dome C: consequences on stress-sensitive innate immune functions.

Feuerecker M, Crucian B, Salam AP, Rybka A, Kaufmann I, Moreels M, Quintens R, Schelling G, Thiel M, Baatout S, Sams C, Choukèr A.

High Alt Med Biol. 2014 Sep;15(3):341-8. doi: 10.1089/ham.2013.1128. Epub 2014 Aug 6.

PMID:
25099674
32.

Multiple latent viruses reactivate in astronauts during Space Shuttle missions.

Mehta SK, Laudenslager ML, Stowe RP, Crucian BE, Sams CF, Pierson DL.

Brain Behav Immun. 2014 Oct;41:210-7. doi: 10.1016/j.bbi.2014.05.014. Epub 2014 Jun 2.

PMID:
24886968
33.

Plasma cytokine concentrations indicate that in vivo hormonal regulation of immunity is altered during long-duration spaceflight.

Crucian BE, Zwart SR, Mehta S, Uchakin P, Quiriarte HD, Pierson D, Sams CF, Smith SM.

J Interferon Cytokine Res. 2014 Oct;34(10):778-86. doi: 10.1089/jir.2013.0129. Epub 2014 Apr 4.

34.

Terrestrial stress analogs for spaceflight associated immune system dysregulation.

Crucian B, Simpson RJ, Mehta S, Stowe R, Chouker A, Hwang SA, Actor JK, Salam AP, Pierson D, Sams C.

Brain Behav Immun. 2014 Jul;39:23-32. doi: 10.1016/j.bbi.2014.01.011. Epub 2014 Jan 24. Review.

PMID:
24462949
35.

Increased dietary iron and radiation in rats promote oxidative stress, induce localized and systemic immune system responses, and alter colon mucosal environment.

Morgan JL, Ritchie LE, Crucian BE, Theriot C, Wu H, Sams C, Smith SM, Turner ND, Zwart SR.

FASEB J. 2014 Mar;28(3):1486-98. doi: 10.1096/fj.13-239418. Epub 2013 Dec 13.

PMID:
24334706
36.

Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells.

Bigley AB, Rezvani K, Chew C, Sekine T, Pistillo M, Crucian B, Bollard CM, Simpson RJ.

Brain Behav Immun. 2014 Jul;39:160-71. doi: 10.1016/j.bbi.2013.10.030. Epub 2013 Nov 5.

PMID:
24200514
37.

Reactivation of latent viruses is associated with increased plasma cytokines in astronauts.

Mehta SK, Crucian BE, Stowe RP, Simpson RJ, Ott CM, Sams CF, Pierson DL.

Cytokine. 2013 Jan;61(1):205-9. doi: 10.1016/j.cyto.2012.09.019. Epub 2012 Oct 26.

PMID:
23107825
38.

Immune system dysregulation occurs during short duration spaceflight on board the space shuttle.

Crucian B, Stowe R, Mehta S, Uchakin P, Quiriarte H, Pierson D, Sams C.

J Clin Immunol. 2013 Feb;33(2):456-65. doi: 10.1007/s10875-012-9824-7. Epub 2012 Oct 26.

PMID:
23100144
39.

Characterization of Epstein-Barr virus reactivation in a modeled spaceflight system.

Brinley AA, Theriot CA, Nelman-Gonzalez M, Crucian B, Stowe RP, Barrett AD, Pierson DL.

J Cell Biochem. 2013 Mar;114(3):616-24. doi: 10.1002/jcb.24403.

PMID:
22991253
40.

A Case Report: PCR-Assisted Diagnosis of Varicella in an Adult.

Mehta SK, Gilden D, Crucian BE, Sams CF, Cohrs RJ, Pierson DL.

Open J Med Microbiol. 2012 Sep;2(3). doi: 10.4236/ojmm.2012.23019.

41.

Monocyte phenotype and cytokine production profiles are dysregulated by short-duration spaceflight.

Crucian B, Stowe R, Quiriarte H, Pierson D, Sams C.

Aviat Space Environ Med. 2011 Sep;82(9):857-62.

PMID:
21888268
42.

Immune system dysregulation during spaceflight: clinical risk for exploration-class missions.

Crucian B, Sams C.

J Leukoc Biol. 2009 Nov;86(5):1017-8. doi: 10.1189/jlb.0709500. No abstract available.

PMID:
19875627
43.

Immune status, latent viral reactivation, and stress during long-duration head-down bed rest.

Crucian BE, Stowe RP, Mehta SK, Yetman DL, Leal MJ, Quiriarte HD, Pierson DL, Sams CF.

Aviat Space Environ Med. 2009 May;80(5 Suppl):A37-44.

PMID:
19476168
44.

Immune system dysregulation following short- vs long-duration spaceflight.

Crucian BE, Stowe RP, Pierson DL, Sams CF.

Aviat Space Environ Med. 2008 Sep;79(9):835-43.

PMID:
18785351
45.

Monitoring immune system function and reactivation of latent viruses in the Artificial Gravity Pilot Study.

Mehta SK, Crucian B, Pierson DL, Sams C, Stowe RP.

J Gravit Physiol. 2007 Jul;14(1):P21-5.

PMID:
18372687
46.

Immune system changes during simulated planetary exploration on Devon Island, high arctic.

Crucian B, Lee P, Stowe R, Jones J, Effenhauser R, Widen R, Sams C.

BMC Immunol. 2007 May 23;8:7.

47.

Rapid flow cytometry method for quantitation of LFA-1-adhesive T cells.

Crucian B, Nelman-Gonzalez M, Sams C.

Clin Vaccine Immunol. 2006 Mar;13(3):403-8.

48.
49.

Laboratory outreach: student assessment of flow cytometer fluidics in zero gravity.

Crucian B, Norman J, Brentz J, Pietrzyk R, Sams C.

Lab Med. 2000 Oct;31(10):569-73.

PMID:
12442765

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