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Items: 7

1.

G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases.

Murga C, Arcones AC, Cruces-Sande M, Briones AM, Salaices M, Mayor F Jr.

Front Pharmacol. 2019 Feb 19;10:112. doi: 10.3389/fphar.2019.00112. eCollection 2019. Review.

2.

Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans.

Cruces-Sande M, Vila-Bedmar R, Arcones AC, González-Rodríguez Á, Rada P, Gutiérrez-de-Juan V, Vargas-Castrillón J, Iruzubieta P, Sánchez-González C, Formentini L, Crespo J, García-Monzón C, Martínez-Chantar ML, Valverde ÁM, Mayor F Jr, Murga C.

Biochim Biophys Acta Mol Basis Dis. 2018 Dec;1864(12):3655-3667. doi: 10.1016/j.bbadis.2018.09.027. Epub 2018 Sep 24.

PMID:
30261289
3.

G protein-coupled receptor kinase 2 (GRK2) as an integrative signalling node in the regulation of cardiovascular function and metabolic homeostasis.

Mayor F Jr, Cruces-Sande M, Arcones AC, Vila-Bedmar R, Briones AM, Salaices M, Murga C.

Cell Signal. 2018 Jan;41:25-32. doi: 10.1016/j.cellsig.2017.04.002. Epub 2017 Apr 4. Review.

PMID:
28389415
4.

Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.

Lucas E, Vila-Bedmar R, Arcones AC, Cruces-Sande M, Cachofeiro V, Mayor F Jr, Murga C.

Cardiovasc Diabetol. 2016 Nov 10;15(1):155.

5.

Molecular physiopathology of obesity-related diseases: multi-organ integration by GRK2.

Lucas E, Cruces-Sande M, Briones AM, Salaices M, Mayor F Jr, Murga C, Vila-Bedmar R.

Arch Physiol Biochem. 2015;121(5):163-77. doi: 10.3109/13813455.2015.1107589. Epub 2015 Dec 7. Review.

6.

Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2.

Vila-Bedmar R, Cruces-Sande M, Lucas E, Willemen HL, Heijnen CJ, Kavelaars A, Mayor F Jr, Murga C.

Sci Signal. 2015 Jul 21;8(386):ra73. doi: 10.1126/scisignal.aaa4374.

7.

Skeletal muscle myogenesis is regulated by G protein-coupled receptor kinase 2.

Garcia-Guerra L, Vila-Bedmar R, Carrasco-Rando M, Cruces-Sande M, Martín M, Ruiz-Gómez A, Ruiz-Gómez M, Lorenzo M, Fernández-Veledo S, Mayor F Jr, Murga C, Nieto-Vázquez I.

J Mol Cell Biol. 2014 Aug;6(4):299-311. doi: 10.1093/jmcb/mju025. Epub 2014 Jun 13.

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