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Items: 46

1.

Are Conventional Type 1 Dendritic Cells Critical for Protective Antitumor Immunity and How?

Cancel JC, Crozat K, Dalod M, Mattiuz R.

Front Immunol. 2019 Feb 12;10:9. doi: 10.3389/fimmu.2019.00009. eCollection 2019. Review.

2.

Novel Cre-Expressing Mouse Strains Permitting to Selectively Track and Edit Type 1 Conventional Dendritic Cells Facilitate Disentangling Their Complexity in vivo.

Mattiuz R, Wohn C, Ghilas S, Ambrosini M, Alexandre YO, Sanchez C, Fries A, Vu Manh TP, Malissen B, Dalod M, Crozat K.

Front Immunol. 2018 Dec 4;9:2805. doi: 10.3389/fimmu.2018.02805. eCollection 2018.

3.

Profiling MHC II immunopeptidome of blood-stage malaria reveals that cDC1 control the functionality of parasite-specific CD4 T cells.

Draheim M, Wlodarczyk MF, Crozat K, Saliou JM, Alayi TD, Tomavo S, Hassan A, Salvioni A, Demarta-Gatsi C, Sidney J, Sette A, Dalod M, Berry A, Silvie O, Blanchard N.

EMBO Mol Med. 2017 Nov;9(11):1605-1621. doi: 10.15252/emmm.201708123.

4.

An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue.

Tabeta K, Du X, Arimatsu K, Yokoji M, Takahashi N, Amizuka N, Hasegawa T, Crozat K, Maekawa T, Miyauchi S, Matsuda Y, Ida T, Kaku M, Hoebe K, Ohno K, Yoshie H, Yamazaki K, Moresco EMY, Beutler B.

Sci Rep. 2017 Sep 15;7(1):11717. doi: 10.1038/s41598-017-10343-9.

5.

Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery.

Ardouin L, Luche H, Chelbi R, Carpentier S, Shawket A, Montanana Sanchis F, Santa Maria C, Grenot P, Alexandre Y, Grégoire C, Fries A, Vu Manh TP, Tamoutounour S, Crozat K, Tomasello E, Jorquera A, Fossum E, Bogen B, Azukizawa H, Bajenoff M, Henri S, Dalod M, Malissen B.

Immunity. 2016 Aug 16;45(2):305-18. doi: 10.1016/j.immuni.2016.07.019.

6.

XCR1+ dendritic cells promote memory CD8+ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses.

Alexandre YO, Ghilas S, Sanchez C, Le Bon A, Crozat K, Dalod M.

J Exp Med. 2016 Jan 11;213(1):75-92. doi: 10.1084/jem.20142350. Epub 2015 Dec 22.

7.

Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus.

Cocita C, Guiton R, Bessou G, Chasson L, Boyron M, Crozat K, Dalod M.

PLoS Pathog. 2015 May 8;11(5):e1004897. doi: 10.1371/journal.ppat.1004897. eCollection 2015 May.

8.

Plasmacytoid, conventional, and monocyte-derived dendritic cells undergo a profound and convergent genetic reprogramming during their maturation.

Manh TP, Alexandre Y, Baranek T, Crozat K, Dalod M.

Eur J Immunol. 2013 Jul;43(7):1706-15. doi: 10.1002/eji.201243106.

9.

ENU-induced phenovariance in mice: inferences from 587 mutations.

Arnold CN, Barnes MJ, Berger M, Blasius AL, Brandl K, Croker B, Crozat K, Du X, Eidenschenk C, Georgel P, Hoebe K, Huang H, Jiang Z, Krebs P, La Vine D, Li X, Lyon S, Moresco EM, Murray AR, Popkin DL, Rutschmann S, Siggs OM, Smart NG, Sun L, Tabeta K, Webster V, Tomisato W, Won S, Xia Y, Xiao N, Beutler B.

BMC Res Notes. 2012 Oct 24;5:577. doi: 10.1186/1756-0500-5-577.

10.

Differential responses of immune cells to type I interferon contribute to host resistance to viral infection.

Baranek T, Manh TP, Alexandre Y, Maqbool MA, Cabeza JZ, Tomasello E, Crozat K, Bessou G, Zucchini N, Robbins SH, Vivier E, Kalinke U, Ferrier P, Dalod M.

Cell Host Microbe. 2012 Oct 18;12(4):571-84. doi: 10.1016/j.chom.2012.09.002.

11.

Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice.

Rutschmann S, Crozat K, Li X, Du X, Hanselman JC, Shigeoka AA, Brandl K, Popkin DL, McKay DB, Xia Y, Moresco EM, Beutler B.

G3 (Bethesda). 2012 Apr;2(4):499-504. doi: 10.1534/g3.112.002196. Epub 2012 Apr 1.

12.

Inflammatory monocytes and neutrophils are licensed to kill during memory responses in vivo.

Narni-Mancinelli E, Soudja SM, Crozat K, Dalod M, Gounon P, Geissmann F, Lauvau G.

PLoS Pathog. 2011 Dec;7(12):e1002457. doi: 10.1371/journal.ppat.1002457. Epub 2011 Dec 29.

13.

Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type.

Crozat K, Tamoutounour S, Vu Manh TP, Fossum E, Luche H, Ardouin L, Guilliams M, Azukizawa H, Bogen B, Malissen B, Henri S, Dalod M.

J Immunol. 2011 Nov 1;187(9):4411-5. doi: 10.4049/jimmunol.1101717. Epub 2011 Sep 23.

14.

Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice.

Krebs P, Crozat K, Popkin D, Oldstone MB, Beutler B.

Blood. 2011 Jun 16;117(24):6582-8. doi: 10.1182/blood-2011-01-329607. Epub 2011 May 6.

15.

[Human BDCA3 dendritic cells: a promising target for the design of innovative vaccines].

Crozat K, Dalod M.

Med Sci (Paris). 2011 Jan;27(1):25-8. doi: 10.1051/medsci/201127125. French. No abstract available.

16.

Impact of β2 integrin deficiency on mouse natural killer cell development and function.

Crozat K, Eidenschenk C, Jaeger BN, Krebs P, Guia S, Beutler B, Vivier E, Ugolini S.

Blood. 2011 Mar 10;117(10):2874-82. doi: 10.1182/blood-2010-10-315457. Epub 2011 Jan 14.

17.

Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species.

Contreras V, Urien C, Guiton R, Alexandre Y, Vu Manh TP, Andrieu T, Crozat K, Jouneau L, Bertho N, Epardaud M, Hope J, Savina A, Amigorena S, Bonneau M, Dalod M, Schwartz-Cornil I.

J Immunol. 2010 Sep 15;185(6):3313-25. doi: 10.4049/jimmunol.1000824. Epub 2010 Aug 11.

18.

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells.

Crozat K, Guiton R, Contreras V, Feuillet V, Dutertre CA, Ventre E, Vu Manh TP, Baranek T, Storset AK, Marvel J, Boudinot P, Hosmalin A, Schwartz-Cornil I, Dalod M.

J Exp Med. 2010 Jun 7;207(6):1283-92. doi: 10.1084/jem.20100223. Epub 2010 May 17.

19.

Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells.

Eidenschenk C, Crozat K, Krebs P, Arens R, Popkin D, Arnold CN, Blasius AL, Benedict CA, Moresco EM, Xia Y, Beutler B.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9759-64. doi: 10.1073/pnas.1005186107. Epub 2010 May 10.

20.

Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets.

Crozat K, Guiton R, Guilliams M, Henri S, Baranek T, Schwartz-Cornil I, Malissen B, Dalod M.

Immunol Rev. 2010 Mar;234(1):177-98. doi: 10.1111/j.0105-2896.2009.00868.x. Review.

PMID:
20193019
21.

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.

Berger M, Krebs P, Crozat K, Li X, Croker BA, Siggs OM, Popkin D, Du X, Lawson BR, Theofilopoulos AN, Xia Y, Khovananth K, Moresco EM, Satoh T, Takeuchi O, Akira S, Beutler B.

Nat Immunol. 2010 Apr;11(4):335-43. doi: 10.1038/ni.1847. Epub 2010 Feb 28.

22.

Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells.

Guilliams M, Crozat K, Henri S, Tamoutounour S, Grenot P, Devilard E, de Bovis B, Alexopoulou L, Dalod M, Malissen B.

Blood. 2010 Mar 11;115(10):1958-68. doi: 10.1182/blood-2009-09-245274. Epub 2010 Jan 12.

23.

Identification of Mouse Cytomegalovirus Resistance Loci by ENU Mutagenesis.

Crozat K, Georgel P.

Viruses. 2009 Dec;1(3):460-83. doi: 10.3390/v1030460. Epub 2009 Oct 20.

24.

Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.

Barnes MJ, Krebs P, Harris N, Eidenschenk C, Gonzalez-Quintial R, Arnold CN, Crozat K, Sovath S, Moresco EM, Theofilopoulos AN, Beutler B, Hoebe K.

PLoS Biol. 2009 Mar 3;7(3):e51. doi: 10.1371/journal.pbio.1000051.

25.

Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function.

Blasius AL, Brandl K, Crozat K, Xia Y, Khovananth K, Krebs P, Smart NG, Zampolli A, Ruggeri ZM, Beutler BA.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2706-11. doi: 10.1073/pnas.0813208106. Epub 2009 Feb 6.

26.

Crosstalk between components of the innate immune system: promoting anti-microbial defenses and avoiding immunopathologies.

Crozat K, Vivier E, Dalod M.

Immunol Rev. 2009 Jan;227(1):129-49. doi: 10.1111/j.1600-065X.2008.00736.x. Review.

PMID:
19120481
27.

Natural killer cells in immunodefense against infective agents.

Zucchini N, Crozat K, Baranek T, Robbins SH, Altfeld M, Dalod M.

Expert Rev Anti Infect Ther. 2008 Dec;6(6):867-85. doi: 10.1586/14787210.6.6.867. Review.

28.

The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules.

Brzezinska AA, Johnson JL, Munafo DB, Crozat K, Beutler B, Kiosses WB, Ellis BA, Catz SD.

Traffic. 2008 Dec;9(12):2151-64. doi: 10.1111/j.1600-0854.2008.00838.x. Epub 2008 Oct 30.

29.

TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages.

Schabbauer G, Luyendyk J, Crozat K, Jiang Z, Mackman N, Bahram S, Georgel P.

Mol Immunol. 2008 May;45(10):2790-6. doi: 10.1016/j.molimm.2008.02.001. Epub 2008 Mar 12.

30.

ATP-sensitive potassium channels mediate survival during infection in mammals and insects.

Croker B, Crozat K, Berger M, Xia Y, Sovath S, Schaffer L, Eleftherianos I, Imler JL, Beutler B.

Nat Genet. 2007 Dec;39(12):1453-60. Epub 2007 Nov 18.

PMID:
18026101
31.

Genetic analysis of resistance to viral infection.

Beutler B, Eidenschenk C, Crozat K, Imler JL, Takeuchi O, Hoffmann JA, Akira S.

Nat Rev Immunol. 2007 Oct;7(10):753-66. Review.

PMID:
17893693
32.

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis.

Crozat K, Hoebe K, Ugolini S, Hong NA, Janssen E, Rutschmann S, Mudd S, Sovath S, Vivier E, Beutler B.

J Exp Med. 2007 Apr 16;204(4):853-63. Epub 2007 Apr 9. Erratum in: J Exp Med. 2008 Mar 17;205(3):737.

33.

Genetic analysis of innate immunity.

Hoebe K, Jiang Z, Tabeta K, Du X, Georgel P, Crozat K, Beutler B.

Adv Immunol. 2006;91:175-226. Review.

PMID:
16938541
34.

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.

Jiang Z, Georgel P, Li C, Choe J, Crozat K, Rutschmann S, Du X, Bigby T, Mudd S, Sovath S, Wilson IA, Olson A, Beutler B.

Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10961-6. Epub 2006 Jul 10.

35.

Analysis of the MCMV resistome by ENU mutagenesis.

Crozat K, Georgel P, Rutschmann S, Mann N, Du X, Hoebe K, Beutler B.

Mamm Genome. 2006 May;17(5):398-406.

PMID:
16688530
36.

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large.

Beutler B, Jiang Z, Georgel P, Crozat K, Croker B, Rutschmann S, Du X, Hoebe K.

Annu Rev Immunol. 2006;24:353-89. Review.

PMID:
16551253
37.

Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV).

Beutler B, Georgel P, Rutschmann S, Jiang Z, Croker B, Crozat K.

Brief Funct Genomic Proteomic. 2005 Nov;4(3):203-13. Review.

PMID:
16420746
38.

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B.

Nat Immunol. 2006 Feb;7(2):156-64. Epub 2006 Jan 15.

PMID:
16415873
39.

An essential role for Rxr alpha in the development of Th2 responses.

Du X, Tabeta K, Mann N, Crozat K, Mudd S, Beutler B.

Eur J Immunol. 2005 Dec;35(12):3414-23.

40.

A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria.

Georgel P, Crozat K, Lauth X, Makrantonaki E, Seltmann H, Sovath S, Hoebe K, Du X, Rutschmann S, Jiang Z, Bigby T, Nizet V, Zouboulis CC, Beutler B.

Infect Immun. 2005 Aug;73(8):4512-21.

41.

CD36 is a sensor of diacylglycerides.

Hoebe K, Georgel P, Rutschmann S, Du X, Mudd S, Crozat K, Sovath S, Shamel L, Hartung T, Zähringer U, Beutler B.

Nature. 2005 Feb 3;433(7025):523-7.

PMID:
15690042
42.

Genetic dissection of innate immunity to infection: the mouse cytomegalovirus model.

Beutler B, Crozat K, Koziol JA, Georgel P.

Curr Opin Immunol. 2005 Feb;17(1):36-43. Review.

PMID:
15653308
43.

TLR7: A new sensor of viral infection.

Crozat K, Beutler B.

Proc Natl Acad Sci U S A. 2004 May 4;101(18):6835-6. Epub 2004 Apr 27. No abstract available.

44.

Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice.

Du X, Tabeta K, Hoebe K, Liu H, Mann N, Mudd S, Crozat K, Sovath S, Gong X, Beutler B.

Genetics. 2004 Jan;166(1):331-40.

45.

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.

Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, Crozat K, Mudd S, Shamel L, Sovath S, Goode J, Alexopoulou L, Flavell RA, Beutler B.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3516-21. Epub 2004 Mar 1.

46.

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.

Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B.

Nature. 2003 Aug 14;424(6950):743-8. Epub 2003 Jul 20.

PMID:
12872135

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