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Rare Germline Mutations in Complement Regulatory Genes Make the Antiphospholipid Syndrome Catastrophic.

Chaturvedi S, Braunstein EM, Yuan X, Chen H, Alluri RK, Streiff MB, Petri M, Crowther M, McCrae KR, Brodsky RA.

Blood. 2019 Nov 13;134(Supplement_1):4. doi: 10.1182/blood-2019-129115.


Taxonomic status of the Australian dingo: the case for Canis dingo Meyer, 1793.

Smith BP, Cairns KM, Adams JW, Newsome TM, Fillios M, Déaux EC, Parr WCH, Letnic M, VAN Eeden LM, Appleby RG, Bradshaw CJA, Savolainen P, Ritchie EG, Nimmo DG, Archer-Lean C, Greenville AC, Dickman CR, Watson L, Moseby KE, Doherty TS, Wallach AD, Morrant DS, Crowther MS.

Zootaxa. 2019 Mar 4;4564(1):zootaxa.4564.1.6. doi: 10.11646/zootaxa.4564.1.6.


Extended vs. standard-duration thromboprophylaxis in acutely ill medical patients: A systematic review and meta-analysis.

Chiasakul T, Evans CR, Spyropoulos AC, Raskob G, Crowther M, Cuker A.

Thromb Res. 2019 Dec;184:58-61. doi: 10.1016/j.thromres.2019.10.027. Epub 2019 Oct 31. No abstract available.


Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine-A Multicenter Trial.

Harenberg J, Beyer-Westendorf J, Crowther M, Douxfils J, Elalamy I, Verhamme P, Bauersachs R, Hetjens S, Weiss C.

Thromb Haemost. 2019 Nov 8. doi: 10.1055/s-0039-1700545. [Epub ahead of print]


Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial.

Male C, Lensing AWA, Palumbo JS, Kumar R, Nurmeev I, Hege K, Bonnet D, Connor P, Hooimeijer HL, Torres M, Chan AKC, Kenet G, Holzhauer S, Santamaría A, Amedro P, Chalmers E, Simioni P, Bhat RV, Yee DL, Lvova O, Beyer-Westendorf J, Biss TT, Martinelli I, Saracco P, Peters M, Kállay K, Gauger CA, Massicotte MP, Young G, Pap AF, Majumder M, Smith WT, Heubach JF, Berkowitz SD, Thelen K, Kubitza D, Crowther M, Prins MH, Monagle P; EINSTEIN-Jr Phase 3 Investigators.

Lancet Haematol. 2019 Nov 4. pii: S2352-3026(19)30219-4. doi: 10.1016/S2352-3026(19)30219-4. [Epub ahead of print]


Frequency of arterial thromboembolism in populations with malignancies: A systematic review.

Yu J, Li A, Laureano M, Crowther M.

Thromb Res. 2019 Dec;184:16-23. doi: 10.1016/j.thromres.2019.10.004. Epub 2019 Oct 21. Review.


Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial.

Callum J, Farkouh ME, Scales DC, Heddle NM, Crowther M, Rao V, Hucke HP, Carroll J, Grewal D, Brar S, Bussières J, Grocott H, Harle C, Pavenski K, Rochon A, Saha T, Shepherd L, Syed S, Tran D, Wong D, Zeller M, Karkouti K; FIBRES Research Group.

JAMA. 2019 Oct 21:1-11. doi: 10.1001/jama.2019.17312. [Epub ahead of print]


Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta-Analysis.

Chiasakul T, De Jesus E, Tong J, Chen Y, Crowther M, Garcia D, Chai-Adisaksopha C, Messé SR, Cuker A.

J Am Heart Assoc. 2019 Oct;8(19):e012877. doi: 10.1161/JAHA.119.012877. Epub 2019 Sep 24.


Blood transfusion rates following shoulder arthroplasty in a high volume UK centre and analysis of risk factors associated with transfusion.

Dacombe PJ, Kendall JV, McCann P, Packham IN, Sarangi PP, Whitehouse MR, Crowther MA.

Shoulder Elbow. 2019 Jul;11(2 Suppl):67-72. doi: 10.1177/1758573218774317. Epub 2018 May 14.


The risk of major bleeding in patients with suspected heparin-induced thrombocytopenia.

Pishko AM, Lefler DS, Gimotty P, Paydary K, Fardin S, Arepally GM, Crowther M, Rice L, Vega R, Cines DB, Guevara JP, Cuker A.

J Thromb Haemost. 2019 Nov;17(11):1956-1965. doi: 10.1111/jth.14587. Epub 2019 Aug 12.


North America anticoagulation forum guidance on reversal of direct oral anticoagulants.

Shi WG, Crowther M.

Eur J Intern Med. 2019 Sep;67:30-32. doi: 10.1016/j.ejim.2019.07.009. Epub 2019 Jul 22. No abstract available.


Impact of model misspecification in shared frailty survival models.

Gasparini A, Clements MS, Abrams KR, Crowther MJ.

Stat Med. 2019 Oct 15;38(23):4477-4502. doi: 10.1002/sim.8309. Epub 2019 Jul 21.


Antiphospholipid Syndrome During Septic Shock: Hyper- or Hypocoagulability?: A Case Report.

Rezoagli E, Barzaghi N, Crowther M, Dentali F, Pomero F.

A A Pract. 2019 Oct 15;13(8):306-309. doi: 10.1213/XAA.0000000000001061.


Case Report: Two Cases of Strongyloidiasis Presenting with Thrombotic Events.

Waters M, Krajden S, Kim C, Elsobky R, Lychacz B, Cheung M, Crowther M, Keystone J.

Am J Trop Med Hyg. 2019 Aug;101(2):418-421. doi: 10.4269/ajtmh.19-0347.


Perceptions of the impact of non-standard work schedules on health in Australian graduates: an exploratory study.

Crowther ME, Reynolds AC, Ferguson SA, Adams R.

Ind Health. 2019 Jun 8. doi: 10.2486/indhealth.2019-0036. [Epub ahead of print]


Needing a drink: Rainfall and temperature drive the use of free water by a threatened arboreal folivore.

Mella VSA, McArthur C, Krockenberger MB, Frend R, Crowther MS.

PLoS One. 2019 May 29;14(5):e0216964. doi: 10.1371/journal.pone.0216964. eCollection 2019.


Towards regulatory endorsement of drug development tools to promote the application of model-informed drug development in Duchenne muscular dystrophy.

Conrado DJ, Larkindale J, Berg A, Hill M, Burton J, Abrams KR, Abresch RT, Bronson A, Chapman D, Crowther M, Duong T, Gordish-Dressman H, Harnisch L, Henricson E, Kim S, McDonald CM, Schmidt S, Vong C, Wang X, Wong BL, Yong F, Romero K; Duchenne Muscular Dystrophy Regulatory Science Consortium (D-RSC).

J Pharmacokinet Pharmacodyn. 2019 Oct;46(5):441-455. doi: 10.1007/s10928-019-09642-7. Epub 2019 May 24.


Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.

Vincent JL, Francois B, Zabolotskikh I, Daga MK, Lascarrou JB, Kirov MY, Pettilä V, Wittebole X, Meziani F, Mercier E, Lobo SM, Barie PS, Crowther M, Esmon CT, Fareed J, Gando S, Gorelick KJ, Levi M, Mira JP, Opal SM, Parrillo J, Russell JA, Saito H, Tsuruta K, Sakai T, Fineberg D; SCARLET Trial Group.

JAMA. 2019 May 28;321(20):1993-2002. doi: 10.1001/jama.2019.5358.


Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum.

Cuker A, Burnett A, Triller D, Crowther M, Ansell J, Van Cott EM, Wirth D, Kaatz S.

Am J Hematol. 2019 Jun;94(6):697-709. doi: 10.1002/ajh.25475. Epub 2019 Apr 16. Review.


Exploring regional variations in the cross-cultural, international implementation of the Patient Reported Outcomes Burdens and Experience (PROBE) study.

Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A.

Haemophilia. 2019 May;25(3):365-372. doi: 10.1111/hae.13703. Epub 2019 Mar 12.


Extended venous thromboembolism prophylaxis after abdominopelvic cancer surgery: a retrospective review.

Laureano M, Ebraheem M, Crowther M.

Curr Oncol. 2019 Feb;26(1):e106-e110. doi: 10.3747/co.26.4339. Epub 2019 Feb 1.


Genetic differences in Chlamydia pecorum between neighbouring sub-populations of koalas (Phascolarctos cinereus).

Fernandez CM, Schmertmann LJ, Higgins DP, Casteriano A, Irinyi L, Mella VSA, Crowther MS, Meyer W, Krockenberger MB.

Vet Microbiol. 2019 Apr;231:264-270. doi: 10.1016/j.vetmic.2019.02.020. Epub 2019 Feb 12.


Resumption of anticoagulant therapy after anticoagulant-related gastrointestinal bleeding: A systematic review and meta-analysis.

Little D, Chai-Adisaksopha C, Hillis C, Witt DM, Monreal M, Crowther MA, Siegal DM.

Thromb Res. 2019 Mar;175:102-109. doi: 10.1016/j.thromres.2019.01.020. Epub 2019 Jan 30.


Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors.

Connolly SJ, Crowther M, Eikelboom JW, Gibson CM, Curnutte JT, Lawrence JH, Yue P, Bronson MD, Lu G, Conley PB, Verhamme P, Schmidt J, Middeldorp S, Cohen AT, Beyer-Westendorf J, Albaladejo P, Lopez-Sendon J, Demchuk AM, Pallin DJ, Concha M, Goodman S, Leeds J, Souza S, Siegal DM, Zotova E, Meeks B, Ahmad S, Nakamya J, Milling TJ Jr; ANNEXA-4 Investigators.

N Engl J Med. 2019 Apr 4;380(14):1326-1335. doi: 10.1056/NEJMoa1814051. Epub 2019 Feb 7.


Measuring and Analyzing Length of Stay in Critical Care Trials.

Harhay MO, Ratcliffe SJ, Small DS, Suttner LH, Crowther MJ, Halpern SD.

Med Care. 2019 Sep;57(9):e53-e59. doi: 10.1097/MLR.0000000000001059.


Using simulation studies to evaluate statistical methods.

Morris TP, White IR, Crowther MJ.

Stat Med. 2019 May 20;38(11):2074-2102. doi: 10.1002/sim.8086. Epub 2019 Jan 16.


Prevalence of cryptococcal antigenemia and nasal colonization in a free-ranging koala population.

Schmertmann LJ, Kan A, Mella VSA, Fernandez CM, Crowther MS, Madani G, Malik R, Meyer W, Krockenberger MB.

Med Mycol. 2019 Oct 1;57(7):848-857. doi: 10.1093/mmy/myy144.


Systematic Review of Community Paramedicine and EMS Mobile Integrated Health Care Interventions in the United States.

Gregg A, Tutek J, Leatherwood MD, Crawford W, Friend R, Crowther M, McKinney R.

Popul Health Manag. 2019 Jun;22(3):213-222. doi: 10.1089/pop.2018.0114. Epub 2019 Jan 3.


Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study.

Lensing AWA, Male C, Young G, Kubitza D, Kenet G, Patricia Massicotte M, Chan A, Molinari AC, Nowak-Goettl U, Pap ÁF, Adalbo I, Smith WT, Mason A, Thelen K, Berkowitz SD, Crowther M, Schmidt S, Price V, Prins MH, Monagle P.

Thromb J. 2018 Dec 21;16:34. doi: 10.1186/s12959-018-0188-y. eCollection 2018.


Donor Lung Sequence Number and Survival after Lung Transplantation in the United States.

Harhay MO, Porcher R, Thabut G, Crowther MJ, DiSanto T, Rubin S, Penfil Z, Bing Z, Christie JD, Diamond JM, Cantu E.

Ann Am Thorac Soc. 2019 Mar;16(3):313-320. doi: 10.1513/AnnalsATS.201802-100OC.


Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains.

Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A.

Haemophilia. 2019 Jan;25(1):75-83. doi: 10.1111/hae.13649. Epub 2018 Dec 6.


Changes in Body Mass Index and Rates of Death and Transplant in Hemodialysis Patients: A Latent Class Joint Modeling Approach.

Brilleman SL, Moreno-Betancur M, Polkinghorne KR, McDonald SP, Crowther MJ, Thomson J, Wolfe R.

Epidemiology. 2019 Jan;30(1):38-47. doi: 10.1097/EDE.0000000000000931.


American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy.

Witt DM, Nieuwlaat R, Clark NP, Ansell J, Holbrook A, Skov J, Shehab N, Mock J, Myers T, Dentali F, Crowther MA, Agarwal A, Bhatt M, Khatib R, Riva JJ, Zhang Y, Guyatt G.

Blood Adv. 2018 Nov 27;2(22):3257-3291. doi: 10.1182/bloodadvances.2018024893.


Treatment algorithm in cancer-associated thrombosis: Canadian expert consensus.

Carrier M, Blais N, Crowther M, Kavan P, Le Gal G, Moodley O, Shivakumar S, Tagalakis V, Wu C, Lee AYY.

Curr Oncol. 2018 Oct;25(5):329-337. doi: 10.3747/co.25.4266. Epub 2018 Oct 31.


Prospective comparison of the HEP score and 4Ts score for the diagnosis of heparin-induced thrombocytopenia.

Pishko AM, Fardin S, Lefler DS, Paydary K, Vega R, Arepally GM, Crowther M, Rice L, Cines DB, Cuker A.

Blood Adv. 2018 Nov 27;2(22):3155-3162. doi: 10.1182/bloodadvances.2018023077.


Erratum to: Prothrombin Complex Concentrate for Major Bleeding on Factor Xa Inhibitors: A Prospective Cohort Study.

Schulman S, Gross PL, Ritchie B, Nahirniak S, Lin Y, Lieberman L, Carrier M, Crowther MA, Ghosh I, Lazo-Langner A, Zondag M; Study Investigators.

Thromb Haemost. 2018 Dec;118(12):2188. doi: 10.1055/s-0038-1675417. Epub 2018 Nov 12.


Joint longitudinal and time-to-event models for multilevel hierarchical data.

Brilleman SL, Crowther MJ, Moreno-Betancur M, Buros Novik J, Dunyak J, Al-Huniti N, Fox R, Hammerbacher J, Wolfe R.

Stat Methods Med Res. 2019 Dec;28(12):3502-3515. doi: 10.1177/0962280218808821. Epub 2018 Oct 31.


Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies.

Shih AW, Liu A, Elsharawi R, Crowther MA, Cook RJ, Heddle NM.

Transfusion. 2018 Dec;58(12):2841-2860. doi: 10.1111/trf.14952. Epub 2018 Oct 21.


How can we reverse bleeding in patients on direct oral anticoagulants?

Crowther M, Cuker A.

Kardiol Pol. 2019;77(1):3-11. doi: 10.5603/KP.a2018.0197. Epub 2018 Oct 19. Review.


Pre-operative hypertension and intra-operative hypotension: a reply.

Crowther M, Roodt F, Biccard BM.

Anaesthesia. 2018 Nov;73(11):1438-1439. doi: 10.1111/anae.14432. No abstract available.


Andexanet alfa for the treatment of hemorrhage.

Cervi A, Crowther M.

Expert Rev Hematol. 2018 Nov;11(11):847-855. doi: 10.1080/17474086.2018.1532287. Epub 2018 Oct 17. Review.


Higher-risk APS: do we dare to DOAC?

Laureano M, Crowther MA.

Blood. 2018 Sep 27;132(13):1357-1358. doi: 10.1182/blood-2018-08-867036. No abstract available.


Carnivore conservation needs evidence-based livestock protection.

van Eeden LM, Eklund A, Miller JRB, López-Bao JV, Chapron G, Cejtin MR, Crowther MS, Dickman CR, Frank J, Krofel M, Macdonald DW, McManus J, Meyer TK, Middleton AD, Newsome TM, Ripple WJ, Ritchie EG, Schmitz OJ, Stoner KJ, Tourani M, Treves A.

PLoS Biol. 2018 Sep 18;16(9):e2005577. doi: 10.1371/journal.pbio.2005577. eCollection 2018 Sep.


Weight-adjusted tinzaparin for the prevention of venous thromboembolism after bariatric surgery.

Tseng EK, Kolesar E, Handa P, Douketis JD, Anvari M, Tiboni M, Crowther MA, Siegal DM.

J Thromb Haemost. 2018 Oct;16(10):2008-2015. doi: 10.1111/jth.14263. Epub 2018 Aug 31.


Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire.

Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther M, Iorio A.

BMJ Open. 2018 Aug 8;8(8):e021900. doi: 10.1136/bmjopen-2018-021900.


Inferior Vena Cava Filter Placement With Catheter-Directed Lysis: How Did We Get to This Point?

Crowther M, Cervi A.

JACC Cardiovasc Interv. 2018 Jul 23;11(14):1398-1400. doi: 10.1016/j.jcin.2018.06.013. No abstract available.


A multicentre, cross-sectional study investigating the prevalence of hypertensive disease in patients presenting for elective surgery in the Western Cape Province, South Africa.

Van der Spuy K, Crowther M, Nejthardt M, Roodt F, Davids J, Roos J, Cloete E, Pretorius T, Davies G, Van der Walt J, Van der Westhuizen C, Flint M, Swanevelder J, Biccard B.

S Afr Med J. 2018 Jun 26;108(7):590-595. doi: 10.7196/SAMJ.2018.v108i7.13022.


Comparison of argatroban and fondaparinux for the management of patients with isolated heparin-induced thrombocytopenia.

Al-Eidan FAS, Alrawkan S, Alshammary H, Crowther MA.

Ann Hematol. 2018 Nov;97(11):2055-2059. doi: 10.1007/s00277-018-3422-6. Epub 2018 Jul 12.


McMaster RARE-Bestpractices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome.

Legault K, Schunemann H, Hillis C, Yeung C, Akl EA, Carrier M, Cervera R, Crowther M, Dentali F, Erkan D, Espinosa G, Khamashta M, Meerpohl JJ, Moffat K, O'Brien S, Pengo V, Rand JH, Rodriguez Pinto I, Thom L, Iorio A.

J Thromb Haemost. 2018 Jun 7. doi: 10.1111/jth.14192. [Epub ahead of print]


Direct comparative effectiveness and safety between non-vitamin K antagonist oral anticoagulants for stroke prevention in nonvalvular atrial fibrillation: a systematic review and meta-analysis of observational studies.

Li G, Lip GYH, Holbrook A, Chang Y, Larsen TB, Sun X, Tang J, Mbuagbaw L, Witt DM, Crowther M, Thabane L, Levine MAH.

Eur J Epidemiol. 2019 Feb;34(2):173-190. doi: 10.1007/s10654-018-0415-7. Epub 2018 Jun 8.


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