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Items: 41

1.

Osteocytes respond to particles of clinically-relevant conventional and cross-linked polyethylene and metal alloys by up-regulation of resorptive and inflammatory pathways.

Ormsby RT, Solomon LB, Yang D, Crotti TN, Haynes DR, Findlay DM, Atkins GJ.

Acta Biomater. 2019 Mar 15;87:296-306. doi: 10.1016/j.actbio.2019.01.047. Epub 2019 Jan 25.

PMID:
30690207
2.

Osteoclast-Associated Receptor (OSCAR) Distribution in the Synovial Tissues of Patients with Active RA and TNF-α and RANKL Regulation of Expression by Osteoclasts In Vitro.

Dharmapatni AASSK, Algate K, Coleman R, Lorimer M, Cantley MD, Smith MD, Wechalekar MD, Crotti TN.

Inflammation. 2017 Oct;40(5):1566-1575. doi: 10.1007/s10753-017-0597-2.

PMID:
28555364
3.

The effects of tumour necrosis factor-α on bone cells involved in periodontal alveolar bone loss; osteoclasts, osteoblasts and osteocytes.

Algate K, Haynes DR, Bartold PM, Crotti TN, Cantley MD.

J Periodontal Res. 2016 Oct;51(5):549-66. doi: 10.1111/jre.12339. Epub 2015 Dec 15. Review.

PMID:
26667183
4.

Semaphorin-3a, neuropilin-1 and plexin-A1 in prosthetic-particle induced bone loss.

Saad S, Dharmapatni AASSK, Crotti TN, Cantley MD, Algate K, Findlay DM, Atkins GJ, Haynes DR.

Acta Biomater. 2016 Jan;30:311-318. doi: 10.1016/j.actbio.2015.11.025. Epub 2015 Nov 18.

PMID:
26602825
5.

The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice.

Dharmapatni AA, Cantley MD, Marino V, Perilli E, Crotti TN, Smith MD, Haynes DR.

Mediators Inflamm. 2015;2015:564042. doi: 10.1155/2015/564042. Epub 2015 Aug 4.

6.

Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss.

Crotti TN, Dharmapatni AA, Alias E, Haynes DR.

J Immunol Res. 2015;2015:281287. doi: 10.1155/2015/281287. Epub 2015 May 3. Review.

7.

Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue.

Cantley MD, Dharmapatni AA, Algate K, Crotti TN, Bartold PM, Haynes DR.

J Periodontal Res. 2016 Apr;51(2):143-51. doi: 10.1111/jre.12290. Epub 2015 Jun 2.

PMID:
26031835
8.

Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis.

Zawawi MS, Marino V, Perilli E, Cantley MD, Xu J, Purdue PE, Dharmapatni AA, Haynes DR, Crotti TN.

J Biomed Mater Res A. 2015 Nov;103(11):3572-9. doi: 10.1002/jbm.a.35484. Epub 2015 May 29.

PMID:
25903444
9.

Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis.

Zawawi MS, Perilli E, Stansborough RL, Marino V, Cantley MD, Xu J, Dharmapatni AA, Haynes DR, Gibson RJ, Crotti TN.

Calcif Tissue Int. 2015 Jun;96(6):565-74. doi: 10.1007/s00223-015-9982-8. Epub 2015 Mar 25.

PMID:
25804981
10.

Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate.

Purdue PE, Crotti TN, Shen Z, Swantek J, Li J, Hill J, Hanidu A, Dimock J, Nabozny G, Goldring SR, McHugh KP.

Sci Rep. 2014 Dec 23;4:7595. doi: 10.1038/srep07595.

11.

Quantifying not only bone loss, but also soft tissue swelling, in a murine inflammatory arthritis model using micro-computed tomography.

Perilli E, Cantley M, Marino V, Crotti TN, Smith MD, Haynes DR, Dharmapatni AA.

Scand J Immunol. 2015 Feb;81(2):142-50. doi: 10.1111/sji.12259.

12.

Dexamethasone increases αvβ3 integrin expression and affinity through a calcineurin/NFAT pathway.

Faralli JA, Gagen D, Filla MS, Crotti TN, Peters DM.

Biochim Biophys Acta. 2013 Dec;1833(12):3306-3313. doi: 10.1016/j.bbamcr.2013.09.020. Epub 2013 Oct 5.

13.

Bone remodelling in inflammatory arthritis.

Goldring SR, Purdue PE, Crotti TN, Shen Z, Flannery MR, Binder NB, Ross FP, McHugh KP.

Ann Rheum Dis. 2013 Apr;72 Suppl 2:ii52-5. doi: 10.1136/annrheumdis-2012-202199. Epub 2012 Dec 19. Review.

PMID:
23253928
14.

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints.

Crotti TN, Dharmapatni AA, Alias E, Zannettino AC, Smith MD, Haynes DR.

Arthritis Res Ther. 2012 Nov 12;14(6):R245. doi: 10.1186/ar4088.

15.

Regulation of ITAM adaptor molecules and their receptors by inhibition of calcineurin-NFAT signalling during late stage osteoclast differentiation.

Zawawi MS, Dharmapatni AA, Cantley MD, McHugh KP, Haynes DR, Crotti TN.

Biochem Biophys Res Commun. 2012 Oct 19;427(2):404-9. doi: 10.1016/j.bbrc.2012.09.077. Epub 2012 Sep 20.

PMID:
23000414
16.

Polyethylene particles stimulate expression of ITAM-related molecules in peri-implant tissues and when stimulating osteoclastogenesis in vitro.

Alias E, Dharmapatni AS, Holding AC, Atkins GJ, Findlay DM, Howie DW, Crotti TN, Haynes DR.

Acta Biomater. 2012 Aug;8(8):3104-12. doi: 10.1016/j.actbio.2012.04.037. Epub 2012 Apr 30.

PMID:
22554886
17.

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis.

Dharmapatni AA, Smith MD, Crotti TN, Holding CA, Vincent C, Weedon HM, Zannettino AC, Zheng TS, Findlay DM, Atkins GJ, Haynes DR.

Arthritis Res Ther. 2011 Mar 24;13(2):R51. doi: 10.1186/ar3294.

18.

Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.

Crotti TN, O'Sullivan RP, Shen Z, Flannery MR, Fajardo RJ, Ross FP, Goldring SR, McHugh KP.

J Cell Physiol. 2011 Dec;226(12):3413-21. doi: 10.1002/jcp.22699.

PMID:
21344395
19.

The role of cell-substrate interaction in regulating osteoclast activation: potential implications in targeting bone loss in rheumatoid arthritis.

McHugh KP, Shen Z, Crotti TN, Flannery MR, O'Sullivan RP, Purdue PE, Goldring SR.

Ann Rheum Dis. 2010 Jan;69 Suppl 1:i83-85. doi: 10.1136/ard.2009.120188. Review.

PMID:
19995752
20.

Snail regulates cell-matrix adhesion by regulation of the expression of integrins and basement membrane proteins.

Haraguchi M, Okubo T, Miyashita Y, Miyamoto Y, Hayashi M, Crotti TN, McHugh KP, Ozawa M.

J Biol Chem. 2008 Aug 29;283(35):23514-23. doi: 10.1074/jbc.M801125200. Epub 2008 Jun 30.

21.

PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.

Crotti TN, Sharma SM, Fleming JD, Flannery MR, Ostrowski MC, Goldring SR, McHugh KP.

J Cell Physiol. 2008 Jun;215(3):636-44. doi: 10.1002/jcp.21344.

PMID:
18288635
22.

Role of cell-matrix interactions in osteoclast differentiation.

McHugh KP, Shen Z, Crotti TN, Flannery MR, Fajardo R, Bierbaum BE, Goldring SR.

Adv Exp Med Biol. 2007;602:107-11.

PMID:
17966395
23.

A novel promoter regulates calcitonin receptor gene expression in human osteoclasts.

Shen Z, Crotti TN, Flannery MR, Matsuzaki K, Goldring SR, McHugh KP.

Biochim Biophys Acta. 2007 Nov-Dec;1769(11-12):659-67. Epub 2007 Sep 12.

PMID:
17949830
24.

Cloning and characterization of osteoclast precursors from the RAW264.7 cell line.

Cuetara BL, Crotti TN, O'Donoghue AJ, McHugh KP.

In Vitro Cell Dev Biol Anim. 2006 Jul-Aug;42(7):182-8.

25.

The role played by cell-substrate interactions in the pathogenesis of osteoclast-mediated peri-implant osteolysis.

Shen Z, Crotti TN, McHugh KP, Matsuzaki K, Gravallese EM, Bierbaum BE, Goldring SR.

Arthritis Res Ther. 2006;8(3):R70. Epub 2006 Apr 13.

26.

NFATc1 regulation of the human beta3 integrin promoter in osteoclast differentiation.

Crotti TN, Flannery M, Walsh NC, Fleming JD, Goldring SR, McHugh KP.

Gene. 2006 May 10;372:92-102. Epub 2006 Mar 2.

27.

NFATc1 directly induces the human beta3 integrin gene in osteoclast differentiation.

Crotti TN, Flannery M, Walsh NC, Fleming JD, Goldring SR, McHugh KP.

J Musculoskelet Neuronal Interact. 2005 Oct-Dec;5(4):335-7. No abstract available.

28.

Rheumatic diseases: the effects of inflammation on bone.

Walsh NC, Crotti TN, Goldring SR, Gravallese EM.

Immunol Rev. 2005 Dec;208:228-51. Review.

PMID:
16313352
29.

Regulation of osteoclast activity in peri-implant tissues.

Haynes DR, Crotti TN, Zreiqat H.

Biomaterials. 2004 Sep;25(20):4877-85. Review.

PMID:
15109848
30.

Regulation of bone lysis in inflammatory diseases.

Haynes DR, Crotti TN.

Inflammopharmacology. 2003;11(4):323-31.

PMID:
15035786
31.

Variability of RANKL and osteoprotegerin staining in synovial tissue from patients with active rheumatoid arthritis: quantification using color video image analysis.

Crotti TN, Ahern MJ, Lange K, Weedon H, Coleman M, Roberts-Thomson PJ, Haynes DR, Smith MD.

J Rheumatol. 2003 Nov;30(11):2319-24.

PMID:
14677171
32.

Factors regulating osteoclast formation in human tissues adjacent to peri-implant bone loss: expression of receptor activator NFkappaB, RANK ligand and osteoprotegerin.

Crotti TN, Smith MD, Findlay DM, Zreiqat H, Ahern MJ, Weedon H, Hatzinikolous G, Capone M, Holding C, Haynes DR.

Biomaterials. 2004 Feb;25(4):565-73.

PMID:
14607494
33.

Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls.

Haynes DR, Barg E, Crotti TN, Holding C, Weedon H, Atkins GJ, Zannetino A, Ahern MJ, Coleman M, Roberts-Thomson PJ, Kraan M, Tak PP, Smith MD.

Rheumatology (Oxford). 2003 Jan;42(1):123-34.

PMID:
12509625
35.

Prosthetic particles modify the expression of bone-related proteins by human osteoblastic cells in vitro.

Zreiqat H, Crotti TN, Howlett CR, Capone M, Markovic B, Haynes DR.

Biomaterials. 2003 Jan;24(2):337-46.

PMID:
12419636
36.

The osteoclastogenic molecules RANKL and RANK are associated with periprosthetic osteolysis.

Haynes DR, Crotti TN, Potter AE, Loric M, Atkins GJ, Howie DW, Findlay DM.

J Bone Joint Surg Br. 2001 Aug;83(6):902-11. Review.

PMID:
11521937
37.

Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint.

Haynes DR, Crotti TN, Loric M, Bain GI, Atkins GJ, Findlay DM.

Rheumatology (Oxford). 2001 Jun;40(6):623-30.

PMID:
11426018
38.

Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation.

Atkins GJ, Haynes DR, Geary SM, Loric M, Crotti TN, Findlay DM.

Bone. 2000 Jun;26(6):653-61.

PMID:
10831938
39.
40.

Bidirectional signaling between stromal and hemopoietic cells regulates interleukin-1 expression during human osteoclast formation.

Haynes DR, Atkins GJ, Loric M, Crotti TN, Geary SM, Findlay DM.

Bone. 1999 Sep;25(3):269-78.

PMID:
10495130
41.

Osteoarthrosis of the facet joints resulting from anular rim lesions in sheep lumbar discs.

Moore RJ, Crotti TN, Osti OL, Fraser RD, Vernon-Roberts B.

Spine (Phila Pa 1976). 1999 Mar 15;24(6):519-25.

PMID:
10101813

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