Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41


The Combination of Curcumin and Salsalate is Superior to Either Agent Alone in Suppressing Pro-Cancerous Molecular Pathways and Colorectal Tumorigenesis in Obese Mice.

Wu X, Koh GY, Huang Y, Crott JW, Bronson RT, Mason JB.

Mol Nutr Food Res. 2019 Apr;63(8):e1801097. doi: 10.1002/mnfr.201801097. Epub 2019 Feb 4.


Interleukin-1 Signaling Mediates Obesity-Promoted Elevations in Inflammatory Cytokines, Wnt Activation, and Epithelial Proliferation in the Mouse Colon.

Pfalzer AC, Crott JW, Koh GY, Smith DE, Garcia PE, Mason JB.

J Interferon Cytokine Res. 2018 Oct;38(10):445-451. doi: 10.1089/jir.2017.0134.


Incremental Elevations in TNFα and IL6 in the Human Colon and Procancerous Changes in the Mucosal Transcriptome Accompany Adiposity.

Pfalzer AC, Leung K, Crott JW, Kim SJ, Tai AK, Parnell LD, Kamanu FK, Liu Z, Rogers G, Shea MK, Garcia PE, Mason JB.

Cancer Epidemiol Biomarkers Prev. 2018 Dec;27(12):1416-1423. doi: 10.1158/1055-9965.EPI-18-0121. Epub 2018 Oct 5.


Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice.

Koh GY, Kane A, Lee K, Xu Q, Wu X, Roper J, Mason JB, Crott JW.

Int J Cancer. 2018 Apr 26. doi: 10.1002/ijc.31559. [Epub ahead of print]


Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice.

Wu X, Pfalzer AC, Koh GY, Tang S, Crott JW, Thomas MJ, Meydani M, Mason JB.

J Agric Food Chem. 2017 Aug 23;65(33):7200-7209. doi: 10.1021/acs.jafc.7b02648. Epub 2017 Aug 11.


Effects of altered parental folate and one-carbon nutrient status on offspring growth and metabolism.

Crott JW.

Mol Aspects Med. 2017 Feb;53:28-35. doi: 10.1016/j.mam.2016.11.001. Epub 2016 Nov 16. Review. No abstract available.


Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and Wnt Pathway in the Intestine of Apc+/1638N Mice: Comparisons and Contrasts.

Liu W, Crott JW, Lyu L, Pfalzer AC, Li J, Choi SW, Yang Y, Mason JB, Liu Z.

J Cancer. 2016 Aug 12;7(13):1780-1790. eCollection 2016.


Interactions between the colonic transcriptome, metabolome, and microbiome in mouse models of obesity-induced intestinal cancer.

Pfalzer AC, Kamanu FK, Parnell LD, Tai AK, Liu Z, Mason JB, Crott JW.

Physiol Genomics. 2016 Aug 1;48(8):545-53. doi: 10.1152/physiolgenomics.00034.2016. Epub 2016 Jun 17.


Correction: Paternal B Vitamin Intake Is a Determinant of Growth, Hepatic Lipid Metabolism and Intestinal Tumor Volume in Female Apc1638N Mouse Offspring.

Sabet JA, Park LK, Iyer LK, Tai AK, Koh GY, Pfalzer AC, Parnell LD, Mason JB, Liu Z, Byun AJ, Crott JW.

PLoS One. 2016 Apr 28;11(4):e0154979. doi: 10.1371/journal.pone.0154979. eCollection 2016.


Paternal B Vitamin Intake Is a Determinant of Growth, Hepatic Lipid Metabolism and Intestinal Tumor Volume in Female Apc1638N Mouse Offspring.

Sabet JA, Park LK, Iyer LK, Tai AK, Koh GY, Pfalzer AC, Parnell LD, Mason JB, Liu Z, Byun AJ, Crott JW.

PLoS One. 2016 Mar 11;11(3):e0151579. doi: 10.1371/journal.pone.0151579. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0154979.


Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc1638N Mice.

Pfalzer AC, Nesbeth PD, Parnell LD, Iyer LK, Liu Z, Kane AV, Chen CY, Tai AK, Bowman TA, Obin MS, Mason JB, Greenberg AS, Choi SW, Selhub J, Paul L, Crott JW.

PLoS One. 2015 Aug 18;10(8):e0135758. doi: 10.1371/journal.pone.0135758. eCollection 2015.


Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.

Byun AJ, Hung KE, Fleet JC, Bronson RT, Mason JB, Garcia PE, Crott JW.

Cancer Lett. 2014 Jun 1;347(2):191-5. doi: 10.1016/j.canlet.2014.03.004. Epub 2014 Mar 14.


Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease.

Selhub J, Byun A, Liu Z, Mason JB, Bronson RT, Crott JW.

J Nutr Biochem. 2013 Dec;24(12):2138-43. doi: 10.1016/j.jnutbio.2013.08.005. Epub 2013 Oct 2.


Folate-genetics and colorectal neoplasia: what we know and need to know next.

Figueiredo JC, Levine AJ, Crott JW, Baurley J, Haile RW.

Mol Nutr Food Res. 2013 Apr;57(4):607-27. doi: 10.1002/mnfr.201200278. Epub 2013 Feb 8. Review.


Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults.

Moorthy D, Peter I, Scott TM, Parnell LD, Lai CQ, Crott JW, Ordovás JM, Selhub J, Griffith J, Rosenberg IH, Tucker KL, Troen AM.

J Nutr. 2012 Aug;142(8):1554-60. doi: 10.3945/jn.112.161828. Epub 2012 Jun 27.


Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer.

Liu Z, Brooks RS, Ciappio ED, Kim SJ, Crott JW, Bennett G, Greenberg AS, Mason JB.

J Nutr Biochem. 2012 Oct;23(10):1207-13. doi: 10.1016/j.jnutbio.2011.07.002. Epub 2011 Dec 29.


Maternal one-carbon nutrient intake and cancer risk in offspring.

Ciappio ED, Mason JB, Crott JW.

Nutr Rev. 2011 Oct;69(10):561-71. doi: 10.1111/j.1753-4887.2011.00424.x. Review.


Maternal B vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis in Apc1638N mouse offspring.

Ciappio ED, Liu Z, Brooks RS, Mason JB, Bronson RT, Crott JW.

Gut. 2011 Dec;60(12):1695-702. doi: 10.1136/gut.2011.240291. Epub 2011 Jun 9.


Combined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice.

Liu Z, Ciappio ED, Crott JW, Brooks RS, Nesvet J, Smith DE, Choi SW, Mason JB.

FASEB J. 2011 Sep;25(9):3136-45. doi: 10.1096/fj.11-184143. Epub 2011 Jun 6.


The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults.

Ye X, Lai CQ, Crott JW, Troen AM, Ordovas JM, Tucker KL.

Psychosom Med. 2011 Jun;73(5):385-92. doi: 10.1097/PSY.0b013e31821a1ab4. Epub 2011 May 19.


Interactions between genetic variants of folate metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican population.

Huang T, Tucker KL, Lee YC, Crott JW, Parnell LD, Shen J, Smith CE, Ordovas JM, Li D, Lai CQ.

Public Health Nutr. 2011 Oct;14(10):1805-12. doi: 10.1017/S1368980011000140. Epub 2011 Feb 22.


Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated fatty acids to modulate plasma homocysteine in puerto rican adults.

Huang T, Tucker KL, Lee YC, Crott JW, Parnell LD, Shen J, Smith CE, Ordovas JM, Li D, Lai CQ.

J Nutr. 2011 Apr 1;141(4):654-9. doi: 10.3945/jn.110.134353. Epub 2011 Jan 26.


Application and adaptation of the in vitro micronucleus assay for the assessment of nutritional requirements of cells for DNA damage prevention.

Bull CF, Beetstra-Hill S, Benassi-Evans BJ, Crott JW, Kimura M, Teo T, Wu J, Fenech MF.

Mutagenesis. 2011 Jan;26(1):193-7. doi: 10.1093/mutage/geq065. Review.


Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells.

Fenech M, Kirsch-Volders M, Natarajan AT, Surralles J, Crott JW, Parry J, Norppa H, Eastmond DA, Tucker JD, Thomas P.

Mutagenesis. 2011 Jan;26(1):125-32. doi: 10.1093/mutage/geq052. Review.


MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.

Lai CQ, Parnell LD, Troen AM, Shen J, Caouette H, Warodomwichit D, Lee YC, Crott JW, Qiu WQ, Rosenberg IH, Tucker KL, Ordovás JM.

Am J Clin Nutr. 2010 May;91(5):1377-86. doi: 10.3945/ajcn.2009.28923. Epub 2010 Mar 24.


Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population.

Chanson A, Parnell LD, Ciappio ED, Liu Z, Crott JW, Tucker KL, Mason JB.

Am J Clin Nutr. 2009 Jun;89(6):1927-36. doi: 10.3945/ajcn.2009.27429. Epub 2009 Apr 29.


Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.

DeVos L, Chanson A, Liu Z, Ciappio ED, Parnell LD, Mason JB, Tucker KL, Crott JW.

Am J Clin Nutr. 2008 Oct;88(4):1149-58.


Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2.

Liu Z, Choi SW, Crott JW, Smith DE, Mason JB.

Int J Cancer. 2008 Aug 1;123(3):519-25. doi: 10.1002/ijc.23599.


Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon.

Liu Z, Choi SW, Crott JW, Keyes MK, Jang H, Smith DE, Kim M, Laird PW, Bronson R, Mason JB.

J Nutr. 2007 Dec;137(12):2701-8.


Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.

van den Donk M, Pellis L, Crott JW, van Engeland M, Friederich P, Nagengast FM, van Bergeijk JD, de Boer SY, Mason JB, Kok FJ, Keijer J, Kampman E.

J Nutr. 2007 Sep;137(9):2114-20.


Older age and dietary folate are determinants of genomic and p16-specific DNA methylation in mouse colon.

Keyes MK, Jang H, Mason JB, Liu Z, Crott JW, Smith DE, Friso S, Choi SW.

J Nutr. 2007 Jul;137(7):1713-7.


Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5-8 of the gene.

Crott JW, Liu Z, Choi SW, Mason JB.

Mutat Res. 2007 Jan 10;626(1-2):171-9. Epub 2006 Nov 13.


A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers.

Gabriel HE, Liu Z, Crott JW, Choi SW, Song BC, Mason JB, Johnson EJ.

Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):993-9.


Chronic cigarette smoking is associated with diminished folate status, altered folate form distribution, and increased genetic damage in the buccal mucosa of healthy adults.

Gabriel HE, Crott JW, Ghandour H, Dallal GE, Choi SW, Keyes MK, Jang H, Liu Z, Nadeau M, Johnston A, Mager D, Mason JB.

Am J Clin Nutr. 2006 Apr;83(4):835-41. Erratum in: Am J Clin Nutr. 2006 Jul;84(1):263.


Accumulation of mitochondrial DNA deletions is age, tissue and folate-dependent in rats.

Crott JW, Choi SW, Branda RF, Mason JB.

Mutat Res. 2005 Feb 15;570(1):63-70.


Effects of dietary folate and aging on gene expression in the colonic mucosa of rats: implications for carcinogenesis.

Crott JW, Choi SW, Ordovas JM, Ditelberg JS, Mason JB.

Carcinogenesis. 2004 Jan;25(1):69-76. Epub 2003 Sep 11.


The effect of folic acid deficiency and MTHFR C677T polymorphism on chromosome damage in human lymphocytes in vitro.

Crott JW, Mashiyama ST, Ames BN, Fenech M.

Cancer Epidemiol Biomarkers Prev. 2001 Oct;10(10):1089-96.


Effect of vitamin C supplementation on chromosome damage, apoptosis and necrosis ex vivo.

Crott JW, Fenech M.

Carcinogenesis. 1999 Jun;20(6):1035-41.


Supplemental Content

Loading ...
Support Center