Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57


IL-1 receptor antagonist, anakinra, prevents myocardial dysfunction in a mouse model of Kawasaki disease vasculitis and myocarditis.

Gorelik M, Lee Y, Abe M, Andrews T, Davis L, Patterson J, Chen S, Crother TR, Aune GJ, Noval Rivas M, Arditi M.

Clin Exp Immunol. 2019 May 17. doi: 10.1111/cei.13314. [Epub ahead of print]


Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection.

Crother TR, Porritt RA, Dagvadorj J, Tumurkhuu G, Slepenkin AV, Peterson EM, Chen S, Shimada K, Arditi M.

Front Immunol. 2019 Apr 12;10:754. doi: 10.3389/fimmu.2019.00754. eCollection 2019.


Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis.

Matundan HH, Sin J, Rivas MN, Fishbein MC, Lehman TJ, Chen S, Gottlieb RA, Crother TR, Abe M, Arditi M.

JCI Insight. 2019 Feb 7;4(3). pii: 126279. doi: 10.1172/jci.insight.126279. [Epub ahead of print]


T-Cell-Intrinsic Receptor Interacting Protein 2 Regulates Pathogenic T Helper 17 Cell Differentiation.

Shimada K, Porritt RA, Markman JL, O'Rourke JG, Wakita D, Noval Rivas M, Ogawa C, Kozhaya L, Martins GA, Unutmaz D, Baloh RH, Crother TR, Chen S, Arditi M.

Immunity. 2018 Nov 20;49(5):873-885.e7. doi: 10.1016/j.immuni.2018.08.022. Epub 2018 Oct 23.


Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice.

Skalski JH, Limon JJ, Sharma P, Gargus MD, Nguyen C, Tang J, Coelho AL, Hogaboam CM, Crother TR, Underhill DM.

PLoS Pathog. 2018 Sep 20;14(9):e1007260. doi: 10.1371/journal.ppat.1007260. eCollection 2018 Sep.


Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells.

Cavassani KA, Meza RJ, Habiel DM, Chen JF, Montes A, Tripathi M, Martins GA, Crother TR, You S, Hogaboam CM, Bhowmick N, Posadas EM.

Cancer Med. 2018 Sep;7(9):4639-4649. doi: 10.1002/cam4.1695. Epub 2018 Aug 9.


Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.

Tumurkhuu G, Dagvadorj J, Porritt RA, Crother TR, Shimada K, Tarling EJ, Erbay E, Arditi M, Chen S.

Cell Metab. 2018 Sep 4;28(3):432-448.e4. doi: 10.1016/j.cmet.2018.05.027. Epub 2018 Jun 21.


Optimal tube length of orotracheal intubation for mice.

Nosaka N, Crother TR, Chen S, Arditi M, Shimada K.

Lab Anim. 2019 Feb;53(1):79-83. doi: 10.1177/0023677218765032. Epub 2018 Apr 13.


Chlamydia and Lipids Engage a Common Signaling Pathway That Promotes Atherogenesis.

Chen S, Shimada K, Crother TR, Erbay E, Shah PK, Arditi M.

J Am Coll Cardiol. 2018 Apr 10;71(14):1553-1570. doi: 10.1016/j.jacc.2018.01.072.


Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis.

Domiciano TP, Wakita D, Jones HD, Crother TR, Verri WA Jr, Arditi M, Shimada K.

Sci Rep. 2017 Feb 2;7:41539. doi: 10.1038/srep41539.


The microbiome in asthma.

Noval Rivas M, Crother TR, Arditi M.

Curr Opin Pediatr. 2016 Dec;28(6):764-771. Review.


CD8+ T Cells Contribute to the Development of Coronary Arteritis in the Lactobacillus casei Cell Wall Extract-Induced Murine Model of Kawasaki Disease.

Noval Rivas M, Lee Y, Wakita D, Chiba N, Dagvadorj J, Shimada K, Chen S, Fishbein MC, Lehman TJ, Crother TR, Arditi M.

Arthritis Rheumatol. 2017 Feb;69(2):410-421. doi: 10.1002/art.39939.


Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis.

Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S, Arditi M.

Circ Res. 2016 Sep 2;119(6):e76-90. doi: 10.1161/CIRCRESAHA.116.308362. Epub 2016 Jul 6.


Immunological Consequences of Intestinal Fungal Dysbiosis.

Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR, Arditi M, Underhill DM, Iliev ID.

Cell Host Microbe. 2016 Jun 8;19(6):865-73. doi: 10.1016/j.chom.2016.05.003. Epub 2016 May 26.


Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic Aneurysm.

Wakita D, Kurashima Y, Crother TR, Noval Rivas M, Lee Y, Chen S, Fury W, Bai Y, Wagner S, Li D, Lehman T, Fishbein MC, Hoffman HM, Shah PK, Shimada K, Arditi M.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):886-97. doi: 10.1161/ATVBAHA.115.307072. Epub 2016 Mar 3.


Chlamydia pneumoniae Infection and Inflammatory Diseases.

Porritt RA, Crother TR.

For Immunopathol Dis Therap. 2016;7(3-4):237-254. doi: 10.1615/ForumImmunDisTher.2017020161.


IL-1 Signaling Is Critically Required in Stromal Cells in Kawasaki Disease Vasculitis Mouse Model: Role of Both IL-1α and IL-1β.

Lee Y, Wakita D, Dagvadorj J, Shimada K, Chen S, Huang G, Lehman TJ, Fishbein MC, Hoffman HM, Crother TR, Arditi M.

Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2605-16. doi: 10.1161/ATVBAHA.115.306475. Epub 2015 Oct 29.


POPsicle for Fever! Cooling Down the Inflammasome.

Shimada K, Crother TR, Arditi M.

Immunity. 2015 Aug 18;43(2):213-5. doi: 10.1016/j.immuni.2015.08.004.


Correction: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.

Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K.

PLoS One. 2015 May 21;10(5):e0128735. doi: 10.1371/journal.pone.0128735. eCollection 2015. No abstract available.


Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.

Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K.

PLoS One. 2015 Apr 13;10(4):e0123460. doi: 10.1371/journal.pone.0123460. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128735.


Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release.

Dagvadorj J, Shimada K, Chen S, Jones HD, Tumurkhuu G, Zhang W, Wawrowsky KA, Crother TR, Arditi M.

Immunity. 2015 Apr 21;42(4):640-53. doi: 10.1016/j.immuni.2015.03.007. Epub 2015 Apr 7.


Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway.

Chiba N, Shimada K, Chen S, Jones HD, Alsabeh R, Slepenkin AV, Peterson E, Crother TR, Arditi M.

J Immunol. 2015 Apr 15;194(8):3840-51. doi: 10.4049/jimmunol.1402685. Epub 2015 Mar 9.


A single infection with Chlamydia pneumoniae is sufficient to exacerbate atherosclerosis in ApoE deficient mice.

Sorrentino R, Yilmaz A, Schubert K, Crother TR, Pinto A, Shimada K, Arditi M, Chen S.

Cell Immunol. 2015 Mar;294(1):25-32. doi: 10.1016/j.cellimm.2015.01.007. Epub 2015 Jan 30.


Alternatively spliced myeloid differentiation protein-2 inhibits TLR4-mediated lung inflammation.

Tumurkhuu G, Dagvadorj J, Jones HD, Chen S, Shimada K, Crother TR, Arditi M.

J Immunol. 2015 Feb 15;194(4):1686-94. doi: 10.4049/jimmunol.1402123. Epub 2015 Jan 9.


Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis.

Jupelli M, Shimada K, Chiba N, Slepenkin A, Alsabeh R, Jones HD, Peterson E, Chen S, Arditi M, Crother TR.

PLoS One. 2013 Oct 25;8(10):e77447. doi: 10.1371/journal.pone.0077447. eCollection 2013.


The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury.

Jones HD, Crother TR, Gonzalez-Villalobos RA, Jupelli M, Chen S, Dagvadorj J, Arditi M, Shimada K.

Am J Respir Cell Mol Biol. 2014 Feb;50(2):270-80. doi: 10.1165/rcmb.2013-0087OC.


Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice.

Rega A, Terlizzi M, Luciano A, Forte G, Crother TR, Arra C, Arditi M, Pinto A, Sorrentino R.

J Immunol. 2013 Mar 1;190(5):2391-402. doi: 10.4049/jimmunol.1202086. Epub 2013 Jan 25.


Plasmacytoid dendritic cells play a role for effective innate immune responses during Chlamydia pneumoniae infection in mice.

Crother TR, Ma J, Jupelli M, Chiba N, Chen S, Slepenkin A, Alsabeh R, Peterson E, Shimada K, Arditi M.

PLoS One. 2012;7(10):e48655. doi: 10.1371/journal.pone.0048655. Epub 2012 Oct 31.


Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome.

Shimada K, Crother TR, Arditi M.

Microbes Infect. 2012 Nov;14(14):1301-7. doi: 10.1016/j.micinf.2012.08.004. Epub 2012 Sep 5. Review.


Plasmacytoid dendritic cells and their therapeutic activity in cancer.

Pinto A, Rega A, Crother TR, Sorrentino R.

Oncoimmunology. 2012 Aug 1;1(5):726-734.


Marked acceleration of atherosclerosis after Lactobacillus casei-induced coronary arteritis in a mouse model of Kawasaki disease.

Chen S, Lee Y, Crother TR, Fishbein M, Zhang W, Yilmaz A, Shimada K, Schulte DJ, Lehman TJ, Shah PK, Arditi M.

Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):e60-71. doi: 10.1161/ATVBAHA.112.249417. Epub 2012 May 24.


Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease.

Lee Y, Schulte DJ, Shimada K, Chen S, Crother TR, Chiba N, Fishbein MC, Lehman TJ, Arditi M.

Circulation. 2012 Mar 27;125(12):1542-50. doi: 10.1161/CIRCULATIONAHA.111.072769. Epub 2012 Feb 23.


Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.

Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M.

Immunity. 2012 Mar 23;36(3):401-14. doi: 10.1016/j.immuni.2012.01.009. Epub 2012 Feb 16.


Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway.

Gray P, Dagvadorj J, Michelsen KS, Brikos C, Rentsendorj A, Town T, Crother TR, Arditi M.

J Immunol. 2011 Oct 15;187(8):4331-7. doi: 10.4049/jimmunol.1100890. Epub 2011 Sep 14.


Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection.

Shimada K, Crother TR, Karlin J, Chen S, Chiba N, Ramanujan VK, Vergnes L, Ojcius DM, Arditi M.

PLoS One. 2011;6(6):e21477. doi: 10.1371/journal.pone.0021477. Epub 2011 Jun 23.


Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells.

Crother TR, Schröder NW, Karlin J, Chen S, Shimada K, Slepenkin A, Alsabeh R, Peterson E, Arditi M.

PLoS One. 2011;6(6):e20784. doi: 10.1371/journal.pone.0020784. Epub 2011 Jun 10.


Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis.

Soliman A, Michelsen KS, Karahashi H, Lu J, Meng FJ, Qu X, Crother TR, Rabizadeh S, Chen S, Caplan MS, Arditi M, Jilling T.

PLoS One. 2010 Oct 15;5(10):e15044. doi: 10.1371/journal.pone.0015044.


IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice.

Chen S, Shimada K, Zhang W, Huang G, Crother TR, Arditi M.

J Immunol. 2010 Nov 1;185(9):5619-27. doi: 10.4049/jimmunol.1001879. Epub 2010 Oct 8.


Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.

Lowe EL, Crother TR, Rabizadeh S, Hu B, Wang H, Chen S, Shimada K, Wong MH, Michelsen KS, Arditi M.

PLoS One. 2010 Sep 27;5(9):e13027. doi: 10.1371/journal.pone.0013027.


Plasmacytoid dendritic cells alter the antitumor activity of CpG-oligodeoxynucleotides in a mouse model of lung carcinoma.

Sorrentino R, Morello S, Luciano A, Crother TR, Maiolino P, Bonavita E, Arra C, Adcock IM, Arditi M, Pinto A.

J Immunol. 2010 Oct 15;185(8):4641-50. doi: 10.4049/jimmunol.1000881. Epub 2010 Sep 20.


Emerging role of IL-17 in atherosclerosis.

Chen S, Crother TR, Arditi M.

J Innate Immun. 2010;2(4):325-33. doi: 10.1159/000314626. Epub 2010 May 7. Review.


Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.

Gray P, Michelsen KS, Sirois CM, Lowe E, Shimada K, Crother TR, Chen S, Brikos C, Bulut Y, Latz E, Underhill D, Arditi M.

J Immunol. 2010 Jun 1;184(11):6359-66. doi: 10.4049/jimmunol.0903543. Epub 2010 Apr 30.


Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses.

Sorrentino R, Gray P, Chen S, Shimada K, Crother TR, Arditi M.

Am J Respir Cell Mol Biol. 2010 Oct;43(4):422-31. doi: 10.1165/rcmb.2009-0224OC. Epub 2009 Nov 9.


Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking Kawasaki disease.

Schulte DJ, Yilmaz A, Shimada K, Fishbein MC, Lowe EL, Chen S, Wong M, Doherty TM, Lehman T, Crother TR, Sorrentino R, Arditi M.

J Immunol. 2009 Oct 15;183(8):5311-8. doi: 10.4049/jimmunol.0901395. Epub 2009 Sep 28.


Chlamydial heat shock protein 60 induces acute pulmonary inflammation in mice via the Toll-like receptor 4- and MyD88-dependent pathway.

Bulut Y, Shimada K, Wong MH, Chen S, Gray P, Alsabeh R, Doherty TM, Crother TR, Arditi M.

Infect Immun. 2009 Jul;77(7):2683-90. doi: 10.1128/IAI.00248-09. Epub 2009 Apr 27.


The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection.

Shimada K, Chen S, Dempsey PW, Sorrentino R, Alsabeh R, Slepenkin AV, Peterson E, Doherty TM, Underhill D, Crother TR, Arditi M.

PLoS Pathog. 2009 Apr;5(4):e1000379. doi: 10.1371/journal.ppat.1000379. Epub 2009 Apr 10. Erratum in: PLoS Pathog. 2009 Apr;5(4). doi: 10.1371/annotation/f3aa682e-3bc2-4a05-ac7f-05c6cfe1bbd7. PLoS Pathog. 2009 Apr;5(4). doi: 10.1371/annotation/0f4b8a96-1598-4c90-b816-8fbe7614310b.


Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation.

Chen S, Sorrentino R, Shimada K, Bulut Y, Doherty TM, Crother TR, Arditi M.

J Immunol. 2008 Nov 15;181(10):7186-93.


TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis.

Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M.

J Immunol. 2008 Nov 15;181(10):7176-85.


Innate immune responses during respiratory tract infection with a bacterial pathogen induce allergic airway sensitization.

Schröder NW, Crother TR, Naiki Y, Chen S, Wong MH, Yilmaz A, Slepenkin A, Schulte D, Alsabeh R, Doherty TM, Peterson E, Nel AE, Arditi M.

J Allergy Clin Immunol. 2008 Sep;122(3):595-602.e5. doi: 10.1016/j.jaci.2008.06.038.


Analysis of bacterial membrane proteins produced during mammalian infection using hydrophobic antigen tissue triton extraction (HATTREX).

Crother TR, Nally JE.

Curr Protoc Microbiol. 2008 May;Chapter 12:Unit 12.1. doi: 10.1002/9780471729259.mc1201s9.


Supplemental Content

Loading ...
Support Center