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Items: 1 to 50 of 203

1.

A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive.

Hovel-Miner G, Mugnier MR, Goldwater B, Cross GA, Papavasiliou FN.

PLoS Genet. 2016 May 5;12(5):e1005994. doi: 10.1371/journal.pgen.1005994. eCollection 2016 May.

2.

The in vivo dynamics of antigenic variation in Trypanosoma brucei.

Mugnier MR, Cross GA, Papavasiliou FN.

Science. 2015 Mar 27;347(6229):1470-3. doi: 10.1126/science.aaa4502.

3.

[Thyroid dysfunction in adults infected by human immunodeficiency virus].

Abelleira E, De Cross GA, Pitoia F.

Medicina (B Aires). 2014;74(4):315-20. Review. Spanish.

4.

Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427.

Cross GA, Kim HS, Wickstead B.

Mol Biochem Parasitol. 2014 Jun;195(1):59-73. doi: 10.1016/j.molbiopara.2014.06.004. Epub 2014 Jun 30.

5.

Strategies to construct null and conditional null Trypanosoma brucei mutants using Cre-recombinase and loxP.

Kim HS, Li Z, Boothroyd C, Cross GA.

Mol Biochem Parasitol. 2013 Sep;191(1):16-9. doi: 10.1016/j.molbiopara.2013.08.001. Epub 2013 Aug 13.

6.

MCM-BP is required for repression of life-cycle specific genes transcribed by RNA polymerase I in the mammalian infectious form of Trypanosoma brucei.

Kim HS, Park SH, Günzl A, Cross GA.

PLoS One. 2013;8(2):e57001. doi: 10.1371/journal.pone.0057001. Epub 2013 Feb 25.

7.

Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein.

Kolev NG, Ramey-Butler K, Cross GA, Ullu E, Tschudi C.

Science. 2012 Dec 7;338(6112):1352-3. doi: 10.1126/science.1229641.

8.

Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching.

Benmerzouga I, Concepción-Acevedo J, Kim HS, Vandoros AV, Cross GA, Klingbeil MM, Li B.

Mol Microbiol. 2013 Jan;87(1):196-210. doi: 10.1111/mmi.12093. Epub 2012 Dec 10.

9.

The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism.

Das A, Morales R, Banday M, Garcia S, Hao L, Cross GA, Estevez AM, Bellofatto V.

RNA. 2012 Nov;18(11):1968-83. doi: 10.1261/rna.033829.112. Epub 2012 Sep 10.

10.

Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei.

Hovel-Miner GA, Boothroyd CE, Mugnier M, Dreesen O, Cross GA, Papavasiliou FN.

PLoS Pathog. 2012;8(8):e1002900. doi: 10.1371/journal.ppat.1002900. Epub 2012 Aug 30.

11.

A unified phylogeny-based nomenclature for histone variants.

Talbert PB, Ahmad K, Almouzni G, Ausió J, Berger F, Bhalla PL, Bonner WM, Cande WZ, Chadwick BP, Chan SW, Cross GA, Cui L, Dimitrov SI, Doenecke D, Eirin-López JM, Gorovsky MA, Hake SB, Hamkalo BA, Holec S, Jacobsen SE, Kamieniarz K, Khochbin S, Ladurner AG, Landsman D, Latham JA, Loppin B, Malik HS, Marzluff WF, Pehrson JR, Postberg J, Schneider R, Singh MB, Smith MM, Thompson E, Torres-Padilla ME, Tremethick DJ, Turner BM, Waterborg JH, Wollmann H, Yelagandula R, Zhu B, Henikoff S.

Epigenetics Chromatin. 2012 Jun 21;5:7. doi: 10.1186/1756-8935-5-7.

12.

Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation.

Kim HS, Cross GA.

PLoS One. 2011;6(9):e25313. doi: 10.1371/journal.pone.0025313. Epub 2011 Sep 28.

13.

Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing.

Siegel TN, Gunasekera K, Cross GA, Ochsenreiter T.

Trends Parasitol. 2011 Oct;27(10):434-41. doi: 10.1016/j.pt.2011.05.006. Epub 2011 Jul 6. Review.

14.

The naming of genes.

Cross GA.

Trends Parasitol. 2011 Aug;27(8):329. doi: 10.1016/j.pt.2011.05.002. Epub 2011 Jun 12. No abstract available.

PMID:
21664186
15.

TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.

Kim HS, Cross GA.

PLoS Pathog. 2010 Jul 8;6(7):e1000992. doi: 10.1371/journal.ppat.1000992.

16.

Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites.

Siegel TN, Hekstra DR, Wang X, Dewell S, Cross GA.

Nucleic Acids Res. 2010 Aug;38(15):4946-57. doi: 10.1093/nar/gkq237. Epub 2010 Apr 12.

17.

Drug discovery: Fat-free proteins kill parasites.

Cross GA.

Nature. 2010 Apr 1;464(7289):689-90. doi: 10.1038/464689a. No abstract available.

PMID:
20360728
18.

Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei.

Wright JR, Siegel TN, Cross GA.

Mol Biochem Parasitol. 2010 Aug;172(2):141-4. doi: 10.1016/j.molbiopara.2010.03.013. Epub 2010 Mar 27.

19.

Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.

Cliffe LJ, Siegel TN, Marshall M, Cross GA, Sabatini R.

Nucleic Acids Res. 2010 Jul;38(12):3923-35. doi: 10.1093/nar/gkq146. Epub 2010 Mar 9.

20.

Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes.

Figueiredo LM, Cross GA.

Eukaryot Cell. 2010 Jan;9(1):148-54. doi: 10.1128/EC.00282-09. Epub 2009 Nov 13.

21.

Epigenetic regulation in African trypanosomes: a new kid on the block.

Figueiredo LM, Cross GA, Janzen CJ.

Nat Rev Microbiol. 2009 Jul;7(7):504-13. doi: 10.1038/nrmicro2149. Review.

PMID:
19528957
22.

A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei.

Boothroyd CE, Dreesen O, Leonova T, Ly KI, Figueiredo LM, Cross GA, Papavasiliou FN.

Nature. 2009 May 14;459(7244):278-81. doi: 10.1038/nature07982. Epub 2009 Apr 15.

23.

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei.

Siegel TN, Hekstra DR, Kemp LE, Figueiredo LM, Lowell JE, Fenyo D, Wang X, Dewell S, Cross GA.

Genes Dev. 2009 May 1;23(9):1063-76. doi: 10.1101/gad.1790409. Epub 2009 Apr 15.

24.

Fatal outcome of a young woman with papillary thyroid carcinoma and graves' disease: possible implication of "cross-signalling" mechanism.

Cross GA, Suarez H, Pitoia F, Moncet D, Vanegas M, Bruno OD, Niepomniszcze H.

Arq Bras Endocrinol Metabol. 2008 Oct;52(7):1194-200.

25.

Telomeric expression sites are highly conserved in Trypanosoma brucei.

Hertz-Fowler C, Figueiredo LM, Quail MA, Becker M, Jackson A, Bason N, Brooks K, Churcher C, Fahkro S, Goodhead I, Heath P, Kartvelishvili M, Mungall K, Harris D, Hauser H, Sanders M, Saunders D, Seeger K, Sharp S, Taylor JE, Walker D, White B, Young R, Cross GA, Rudenko G, Barry JD, Louis EJ, Berriman M.

PLoS One. 2008;3(10):e3527. doi: 10.1371/journal.pone.0003527. Epub 2008 Oct 27.

26.

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes.

Kawahara T, Siegel TN, Ingram AK, Alsford S, Cross GA, Horn D.

Mol Microbiol. 2008 Aug;69(4):1054-68. doi: 10.1111/j.1365-2958.2008.06346.x. Epub 2008 Jul 9.

27.

A histone methyltransferase modulates antigenic variation in African trypanosomes.

Figueiredo LM, Janzen CJ, Cross GA.

PLoS Biol. 2008 Jul 1;6(7):e161. doi: 10.1371/journal.pbio.0060161.

28.

Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging.

Siegel TN, Hekstra DR, Cross GA.

Mol Biochem Parasitol. 2008 Aug;160(2):171-4. doi: 10.1016/j.molbiopara.2008.04.004. Epub 2008 Apr 12.

29.

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation.

Mandava V, Janzen CJ, Cross GA.

Biochem Biophys Res Commun. 2008 Apr 18;368(4):846-51. doi: 10.1016/j.bbrc.2008.01.144. Epub 2008 Feb 7.

30.

Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei.

Siegel TN, Kawahara T, Degrasse JA, Janzen CJ, Horn D, Cross GA.

Mol Microbiol. 2008 Feb;67(4):762-71. doi: 10.1111/j.1365-2958.2007.06079.x. Epub 2007 Dec 30.

31.

CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei.

Scahill MD, Pastar I, Cross GA.

Mol Biochem Parasitol. 2008 Jan;157(1):73-82. Epub 2007 Oct 6.

32.

Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex.

Brandenburg J, Schimanski B, Nogoceke E, Nguyen TN, Padovan JC, Chait BT, Cross GA, Günzl A.

EMBO J. 2007 Nov 28;26(23):4856-66. Epub 2007 Nov 1.

33.

Telomere length in Trypanosoma brucei.

Dreesen O, Cross GA.

Exp Parasitol. 2008 Jan;118(1):103-10. Epub 2007 Aug 29.

34.

Histone modifications in Trypanosoma brucei.

Mandava V, Fernandez JP, Deng H, Janzen CJ, Hake SB, Cross GA.

Mol Biochem Parasitol. 2007 Nov;156(1):41-50. Epub 2007 Jul 17.

35.

An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA.

Rubio MA, Pastar I, Gaston KW, Ragone FL, Janzen CJ, Cross GA, Papavasiliou FN, Alfonzo JD.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7821-6. Epub 2007 May 1.

36.

Telomere structure and function in trypanosomes: a proposal.

Dreesen O, Li B, Cross GA.

Nat Rev Microbiol. 2007 Jan;5(1):70-5. Epub 2006 Dec 11. Review.

PMID:
17160000
37.
38.
39.
40.

Telomerase-independent stabilization of short telomeres in Trypanosoma brucei.

Dreesen O, Cross GA.

Mol Cell Biol. 2006 Jul;26(13):4911-9.

41.

Expression site silencing and life-cycle progression appear normal in Argonaute1-deficient Trypanosoma brucei.

Janzen CJ, van Deursen F, Shi H, Cross GAM, Matthews KR, Ullu E.

Mol Biochem Parasitol. 2006 Sep;149(1):102-107. doi: 10.1016/j.molbiopara.2006.04.005. Epub 2006 May 12. No abstract available.

42.

Unusual histone modifications in Trypanosoma brucei.

Janzen CJ, Fernandez JP, Deng H, Diaz R, Hake SB, Cross GA.

FEBS Lett. 2006 Apr 17;580(9):2306-10. Epub 2006 Mar 24.

43.

Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei.

Lowell JE, Kaiser F, Janzen CJ, Cross GA.

J Cell Sci. 2005 Dec 15;118(Pt 24):5721-30. Epub 2005 Nov 22.

44.

A computational investigation of kinetoplastid trans-splicing.

Gopal S, Awadalla S, Gaasterland T, Cross GA.

Genome Biol. 2005;6(11):R95. Epub 2005 Oct 17.

45.

Systematic study of sequence motifs for RNA trans splicing in Trypanosoma brucei.

Siegel TN, Tan KS, Cross GA.

Mol Cell Biol. 2005 Nov;25(21):9586-94.

46.

Telomere structure and shortening in telomerase-deficient Trypanosoma brucei.

Dreesen O, Li B, Cross GA.

Nucleic Acids Res. 2005 Aug 9;33(14):4536-43. Print 2005.

47.

Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression.

Das A, Zhang Q, Palenchar JB, Chatterjee B, Cross GA, Bellofatto V.

Mol Cell Biol. 2005 Aug;25(16):7314-22.

48.

Trypanosomes at the gates.

Cross GA.

Science. 2005 Jul 15;309(5733):355. No abstract available.

49.

Trypanosome telomeres are protected by a homologue of mammalian TRF2.

Li B, Espinal A, Cross GA.

Mol Cell Biol. 2005 Jun;25(12):5011-21.

50.

Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei.

Janzen CJ, Lander F, Dreesen O, Cross GA.

Nucleic Acids Res. 2004 Dec 15;32(22):6575-84. Print 2004.

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