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Items: 11


Loss of MST/Hippo Signaling in a Genetically Engineered Mouse Model of Fusion-Positive Rhabdomyosarcoma Accelerates Tumorigenesis.

Oristian KM, Crose LES, Kuprasertkul N, Bentley RC, Lin YT, Williams N, Kirsch DG, Linardic CM.

Cancer Res. 2018 Oct 1;78(19):5513-5520. doi: 10.1158/0008-5472.CAN-17-3912. Epub 2018 Aug 9.


The Transcriptional Coactivator TAZ Is a Potent Mediator of Alveolar Rhabdomyosarcoma Tumorigenesis.

Deel MD, Slemmons KK, Hinson AR, Genadry KC, Burgess BA, Crose LES, Kuprasertkul N, Oristian KM, Bentley RC, Linardic CM.

Clin Cancer Res. 2018 Jun 1;24(11):2616-2630. doi: 10.1158/1078-0432.CCR-17-1207. Epub 2018 Mar 7.


A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma.

Slemmons KK, Crose LES, Riedel S, Sushnitha M, Belyea B, Linardic CM.

Mol Cancer Res. 2017 Dec;15(12):1777-1791. doi: 10.1158/1541-7786.MCR-17-0004. Epub 2017 Sep 18.


Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma.

Slemmons KK, Crose LE, Rudzinski E, Bentley RC, Linardic CM.

PLoS One. 2015 Oct 23;10(10):e0140781. doi: 10.1371/journal.pone.0140781. eCollection 2015.


A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas.

Deel MD, Li JJ, Crose LE, Linardic CM.

Front Oncol. 2015 Sep 2;5:190. doi: 10.3389/fonc.2015.00190. eCollection 2015. Review.


Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma.

Kephart JJ, Tiller RG, Crose LE, Slemmons KK, Chen PH, Hinson AR, Bentley RC, Chi JT, Linardic CM.

Clin Cancer Res. 2015 Nov 1;21(21):4868-80. doi: 10.1158/1078-0432.CCR-14-1797. Epub 2015 Jun 12.


Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.

Crose LE, Galindo KA, Kephart JG, Chen C, Fitamant J, Bardeesy N, Bentley RC, Galindo RL, Chi JT, Linardic CM.

J Clin Invest. 2014 Jan;124(1):285-96. doi: 10.1172/JCI67087. Epub 2013 Dec 16.


Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.

Hinson AR, Jones R, Crose LE, Belyea BC, Barr FG, Linardic CM.

Front Oncol. 2013 Jul 17;3:183. doi: 10.3389/fonc.2013.00183. eCollection 2013.


FGFR4 blockade exerts distinct antitumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma.

Crose LE, Etheridge KT, Chen C, Belyea B, Talbot LJ, Bentley RC, Linardic CM.

Clin Cancer Res. 2012 Jul 15;18(14):3780-90. doi: 10.1158/1078-0432.CCR-10-3063. Epub 2012 May 30.


Receptor tyrosine kinases as therapeutic targets in rhabdomyosarcoma.

Crose LE, Linardic CM.

Sarcoma. 2011;2011:756982. doi: 10.1155/2011/756982. Epub 2011 Jan 2.


Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells.

Crose LE, Hilder TL, Sciaky N, Johnson GL.

J Biol Chem. 2009 May 15;284(20):13301-5. doi: 10.1074/jbc.C900009200. Epub 2009 Mar 24.

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