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Items: 45

1.

A limit on the extent to which increased egg size can compensate for a poor postnatal environment revealed experimentally in the burying beetle, Nicrophorus vespilloides.

Schrader M, Crosby RM, Hesketh AR, Jarrett BJ, Kilner RM.

Ecol Evol. 2015 Dec 29;6(1):329-36. doi: 10.1002/ece3.1876. eCollection 2016 Jan.

2.

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers A, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver K, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB.

J Med Chem. 2014 Mar 13;57(5):1902-13. doi: 10.1021/jm400317w. Epub 2013 May 29.

PMID:
23672667
3.

Synthesis and antiviral activity of novel HCV NS3 protease inhibitors with P4 capping groups.

Li X, Liu Y, Zhang YK, Plattner JJ, Baker SJ, Bu W, Liu L, Zhou Y, Ding CZ, Zhang S, Kazmierski WM, Hamatake R, Duan M, Wright LL, Smith GK, Jarvest RL, Ji JJ, Cooper JP, Tallant MD, Crosby RM, Creech K, Wang A.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7351-6. doi: 10.1016/j.bmcl.2012.10.075. Epub 2012 Oct 22.

PMID:
23142614
4.

Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization.

Shotwell JB, Baskaran S, Chong P, Creech KL, Crosby RM, Dickson H, Fang J, Garrido D, Mathis A, Maung J, Parks DJ, Pouliot JJ, Price DJ, Rai R, Seal JW 3rd, Schmitz U, Tai VW, Thomson M, Xie M, Xiong ZZ, Peat AJ.

ACS Med Chem Lett. 2012 May 24;3(7):565-9. doi: 10.1021/ml300090x. eCollection 2012 Jul 12.

5.

Discovery of novel urea-based hepatitis C protease inhibitors with high potency against protease-inhibitor-resistant mutants.

Kazmierski WM, Hamatake R, Duan M, Wright LL, Smith GK, Jarvest RL, Ji JJ, Cooper JP, Tallant MD, Crosby RM, Creech K, Wang A, Li X, Zhang S, Zhang YK, Liu Y, Ding CZ, Zhou Y, Plattner JJ, Baker SJ, Bu W, Liu L.

J Med Chem. 2012 Apr 12;55(7):3021-6. doi: 10.1021/jm201278q. Epub 2012 Apr 3.

PMID:
22471376
6.

Rosiglitazone Induces Mitochondrial Biogenesis in Differentiated Murine 3T3-L1 and C3H/10T1/2 Adipocytes.

Rong JX, Klein JL, Qiu Y, Xie M, Johnson JH, Waters KM, Zhang V, Kashatus JA, Remlinger KS, Bing N, Crosby RM, Jackson TK, Witherspoon SM, Moore JT, Ryan TE, Neill SD, Strum JC.

PPAR Res. 2011;2011:179454. doi: 10.1155/2011/179454. Epub 2011 Oct 15.

7.

Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties.

Li X, Zhang S, Zhang YK, Liu Y, Ding CZ, Zhou Y, Plattner JJ, Baker SJ, Bu W, Liu L, Kazmierski WM, Duan M, Grimes RM, Wright LL, Smith GK, Jarvest RL, Ji JJ, Cooper JP, Tallant MD, Crosby RM, Creech K, Ni ZJ, Zou W, Wright J.

Bioorg Med Chem Lett. 2011 Apr 1;21(7):2048-54. doi: 10.1016/j.bmcl.2011.02.006. Epub 2011 Feb 23.

PMID:
21353550
8.

Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.

Ding CZ, Zhang YK, Li X, Liu Y, Zhang S, Zhou Y, Plattner JJ, Baker SJ, Liu L, Duan M, Jarvest RL, Ji J, Kazmierski WM, Tallant MD, Wright LL, Smith GK, Crosby RM, Wang AA, Ni ZJ, Zou W, Wright J.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7317-22. doi: 10.1016/j.bmcl.2010.10.071. Epub 2010 Oct 21.

PMID:
21067923
9.

Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease.

Li X, Zhang YK, Liu Y, Zhang S, Ding CZ, Zhou Y, Plattner JJ, Baker SJ, Liu L, Bu W, Kazmierski WM, Wright LL, Smith GK, Jarvest RL, Duan M, Ji JJ, Cooper JP, Tallant MD, Crosby RM, Creech K, Ni ZJ, Zou W, Wright J.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7493-7. doi: 10.1016/j.bmcl.2010.10.007. Epub 2010 Oct 30.

PMID:
21041080
10.

Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates.

Li X, Zhang YK, Liu Y, Ding CZ, Zhou Y, Li Q, Plattner JJ, Baker SJ, Zhang S, Kazmierski WM, Wright LL, Smith GK, Grimes RM, Crosby RM, Creech KL, Carballo LH, Slater MJ, Jarvest RL, Thommes P, Hubbard JA, Convery MA, Nassau PM, McDowell W, Skarzynski TJ, Qian X, Fan D, Liao L, Ni ZJ, Pennicott LE, Zou W, Wright J.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5695-700. doi: 10.1016/j.bmcl.2010.08.022. Epub 2010 Aug 10.

PMID:
20801653
11.

Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.

Harris PA, Boloor A, Cheung M, Kumar R, Crosby RM, Davis-Ward RG, Epperly AH, Hinkle KW, Hunter RN 3rd, Johnson JH, Knick VB, Laudeman CP, Luttrell DK, Mook RA, Nolte RT, Rudolph SK, Szewczyk JR, Truesdale AT, Veal JM, Wang L, Stafford JA.

J Med Chem. 2008 Aug 14;51(15):4632-40. doi: 10.1021/jm800566m. Epub 2008 Jul 12.

PMID:
18620382
12.

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity.

Kumar R, Knick VB, Rudolph SK, Johnson JH, Crosby RM, Crouthamel MC, Hopper TM, Miller CG, Harrington LE, Onori JA, Mullin RJ, Gilmer TM, Truesdale AT, Epperly AH, Boloor A, Stafford JA, Luttrell DK, Cheung M.

Mol Cancer Ther. 2007 Jul;6(7):2012-21.

13.

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

Conway JG, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16078-83. Epub 2005 Oct 25.

14.

Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors.

Harris PA, Cheung M, Hunter RN 3rd, Brown ML, Veal JM, Nolte RT, Wang L, Liu W, Crosby RM, Johnson JH, Epperly AH, Kumar R, Luttrell DK, Stafford JA.

J Med Chem. 2005 Mar 10;48(5):1610-9.

PMID:
15743202
15.

Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models.

Dev IK, Dornsife RE, Hopper TM, Onori JA, Miller CG, Harrington LE, Dold KM, Mullin RJ, Johnson JH, Crosby RM, Truesdale AT, Epperly AH, Hinkle KW, Cheung M, Stafford JA, Luttrell DK, Kumar R.

Br J Cancer. 2004 Oct 4;91(7):1391-8.

16.

A prodrug approach to the design of cRaf1 kinase inhibitors with improved cellular activity.

Wood E, Crosby RM, Dickerson S, Frye SV, Griffin R, Hunter R, Jung DK, McDonald OB, McNutt R, Mahony WB, Peel MR, Ray J, Lackey K.

Anticancer Drug Des. 2001 Feb;16(1):1-6.

PMID:
11762640
17.

The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer.

Rusnak DW, Affleck K, Cockerill SG, Stubberfield C, Harris R, Page M, Smith KJ, Guntrip SB, Carter MC, Shaw RJ, Jowett A, Stables J, Topley P, Wood ER, Brignola PS, Kadwell SH, Reep BR, Mullin RJ, Alligood KJ, Keith BR, Crosby RM, Murray DM, Knight WB, Gilmer TM, Lackey K.

Cancer Res. 2001 Oct 1;61(19):7196-203.

18.

Potent dipeptide inhibitors of the pp60c-src SH2 domain.

Pacofsky GJ, Lackey K, Alligood KJ, Berman J, Charifson PS, Crosby RM, Dorsey GF Jr, Feldman PL, Gilmer TM, Hummel CW, Jordan SR, Mohr C, Shewchuk LM, Sternbach DD, Rodriguez M.

J Med Chem. 1998 May 21;41(11):1894-908.

PMID:
9599239
19.

Involvement of pp60c-src with two major signaling pathways in human breast cancer.

Luttrell DK, Lee A, Lansing TJ, Crosby RM, Jung KD, Willard D, Luther M, Rodriguez M, Berman J, Gilmer TM.

Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):83-7.

20.

An examination of narcissistic personality traits as seen in a military population.

Bourgeois JA, Hall MJ, Crosby RM, Drexler KG.

Mil Med. 1993 Mar;158(3):170-4.

PMID:
8487970
21.
22.

Formaldehyde-induced and spontaneous alterations in human hprt DNA sequence and mRNA expression.

Liber HL, Benforado K, Crosby RM, Simpson D, Skopek TR.

Mutat Res. 1989 May;226(1):31-7.

PMID:
2716766
23.

Mutation spectra of N-ethyl-N'-nitro-N-nitrosoguanidine and 1-(2-hydroxyethyl)-1-nitrosourea in Escherichia coli.

Richardson KK, Crosby RM, Skopek TR.

Mol Gen Genet. 1988 Nov;214(3):460-6.

PMID:
3063948
24.

A method for specific cloning and sequencing of human hprt cDNA for mutation analysis.

Simpson D, Crosby RM, Skopek TR.

Biochem Biophys Res Commun. 1988 Feb 29;151(1):487-92.

PMID:
3348790
25.

The cloning, expression, and nucleotide sequence of a gene coding for an immunogenic Brucella abortus protein.

Mayfield JE, Bricker BJ, Godfrey H, Crosby RM, Knight DJ, Halling SM, Balinsky D, Tabatabai LB.

Gene. 1988;63(1):1-9.

PMID:
3133283
26.

Molecular analysis of formaldehyde-induced mutations in human lymphoblasts and E. coli.

Crosby RM, Richardson KK, Craft TR, Benforado KB, Liber HL, Skopek TR.

Environ Mol Mutagen. 1988;12(2):155-66.

PMID:
2900762
27.

DNA base changes induced following in vivo exposure of unadapted, adapted or ada- Escherichia coli to N-methyl-N'-nitro-N-nitrosoguanidine.

Richardson KK, Crosby RM, Richardson FC, Skopek TR.

Mol Gen Genet. 1987 Oct;209(3):526-32.

PMID:
3323828
28.

DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.

Richardson KK, Richardson FC, Crosby RM, Swenberg JA, Skopek TR.

Proc Natl Acad Sci U S A. 1987 Jan;84(2):344-8.

29.

Risk of diagnostic lumbar puncture in acute bacterial meningitis.

Heldrich FJ, Walker SH, Crosby RM.

Pediatr Emerg Care. 1986 Sep;2(3):180-2. No abstract available.

PMID:
3537983
30.

Bovine DNA contains a single major family of interspersed repetitive sequences.

Richardson KK, Crosby RM, Good PJ, Rosen NL, Mayfield JE.

Eur J Biochem. 1986 Jan 15;154(2):349-54.

31.

Catheterization of the cerebral aqueduct for obstructive hydrocephalus in infants.

Crosby RM, Henderson CM, Paul RL.

J Neurosurg. 1973 May;38(5):596-601. No abstract available.

PMID:
4711633
32.

Surgical treatment of hydrocephalus caused by Arnold-Chiari malformation in infants and young children.

Crosby RM, Paul RL, Kosnik EJ.

Am Surg. 1972 Jul;38(7):377-9. No abstract available.

PMID:
5033762
33.

Mycobacterium aquae infection in a hydrocephalic child (Mycobacterium aquae meningitis).

Gonzales EP, Crosby RM, Walker SH.

Pediatrics. 1971 Dec;48(6):974-7. No abstract available.

PMID:
5129457
34.

Treatment of hydrocephalus: direct attach on the obstruction.

Crosby RM, Paul RL.

Am Surg. 1969 Oct;35(10):701-4. No abstract available.

PMID:
5824342
35.

The significance of subdural air in pneumoencephalograms in infants.

BOUDREAU RP, CROSBY RM.

Am J Roentgenol Radium Ther Nucl Med. 1958 Sep;80(3):429-35. No abstract available.

PMID:
13571494
36.

Subdural collections of fluid in infants and children. III. The chronic membrane.

CROSBY RM.

Clin Neurosurg. 1957-1958;5:66-72; discussion 72-6. No abstract available.

PMID:
13597137
37.

Subdural collections of fluid in infants and children. I. Visualization of the capsule with thorium dioxide.

CROSBY RM, DENNIS JM.

Am J Roentgenol Radium Ther Nucl Med. 1956 Sep;76(3):507-11. No abstract available.

PMID:
13354840
38.

Subdural collections of fluid in infants and children. II. Study with radioactive sodium phosphate (P-32).

CROSBY RM, BAUER RE.

J Neurosurg. 1956 Mar;13(2):140-4. No abstract available.

PMID:
13307289
39.

Xanthochromia of the cerebrospinal fluid. II. Preliminary description of several new colored substances.

CROSBY RM, WEILAND GL.

AMA Arch Neurol Psychiatry. 1953 Jun;69(6):732-6. No abstract available.

PMID:
13050226
40.

Intradural lipoma of the spinal cord.

CROSBY RM, WAGNER JA, NICHOLS P Jr.

J Neurosurg. 1953 Jan;10(1):81-6. No abstract available.

PMID:
13023453
41.

Treatment of post-pneumoencephalographic headache with beta-pyridyl carbinol tartrate (roniacol tartrate).

CROSBY RM.

Am J Med Sci. 1953 Jan;225(1):61-6. No abstract available.

PMID:
13007697
42.

Head rest for experimental cranial surgery.

THOMPSON RK, SMITH GW, CROSBY RM.

J Neuropathol Exp Neurol. 1951 Jul;10(3):338-40. No abstract available.

PMID:
14861669
43.

Intrauterine meningitis as a cause of hydrocephalus.

CROSBY RM, MOSBERG WH Jr, SMITH GW.

J Pediatr. 1951 Jul;39(1):94-101. No abstract available.

PMID:
14851191
44.

Xanthochromia of the cerebrospinal fluid; an accurate method for quantitative determination.

CROSBY RM, ALVAREZ-de CHOUDENS JA, THOMPSON RK, WEILAND GL.

Bull Sch Med Univ Md. 1950 Apr;35(2):62-4. No abstract available.

PMID:
24537064
45.

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