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Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment.

Drakvik E, Altenburger R, Aoki Y, Backhaus T, Bahadori T, Barouki R, Brack W, Cronin MTD, Demeneix B, Hougaard Bennekou S, van Klaveren J, Kneuer C, Kolossa-Gehring M, Lebret E, Posthuma L, Reiber L, Rider C, Rüegg J, Testa G, van der Burg B, van der Voet H, Warhurst AM, van de Water B, Yamazaki K, Öberg M, Bergman Å.

Environ Int. 2019 Nov 5;134:105267. doi: 10.1016/j.envint.2019.105267. [Epub ahead of print]


Frankel 2 appliance versus the Modified Twin Block appliance for Phase 1 treatment of Class II division 1 malocclusion in children and adolescents: A randomized clinical trial.

Campbell C, Millett D, Kelly N, Cooke M, Cronin M.

Angle Orthod. 2019 Oct 15. doi: 10.2319/042419-290.1. [Epub ahead of print]


Measuring Local Electric Fields and Local Charge Densities at Electrode Surfaces Using Graphene-Enhanced Raman Spectroscopy (GERS)-Based Stark-Shifts.

Shi H, Zhao B, Ma J, Bronson MJ Jr, Cai Z, Chen J, Wang Y, Cronin M, Jensen L, Cronin SB.

ACS Appl Mater Interfaces. 2019 Oct 2;11(39):36252-36258. doi: 10.1021/acsami.9b11892. Epub 2019 Sep 23.


Finding synergies for the 3Rs - Repeated Dose Toxicity testing: Report from an EPAA Partners' Forum.

Laroche C, Annys E, Bender H, Botelho D, Botham P, Brendler-Schwaab S, Clayton R, Corvaro M, Dal Negro G, Delannois F, Dent M, Desaintes C, Desprez B, Dhalluin S, Hartmann A, Hoffmann-Doerr S, Hubesch B, Irizar A, Manou I, Müller BP, Nadzialek S, Prieto P, Rasenberg M, Roggeband R, Rowan TG, Schutte K, van de Water B, Westmoreland C, Whelan M, Wilschut A, Zvonimir Z, Cronin MTD.

Regul Toxicol Pharmacol. 2019 Nov;108:104470. doi: 10.1016/j.yrtph.2019.104470. Epub 2019 Aug 31.


Development and analysis of an adverse outcome pathway network for human neurotoxicity.

Spinu N, Bal-Price A, Cronin MTD, Enoch SJ, Madden JC, Worth AP.

Arch Toxicol. 2019 Oct;93(10):2759-2772. doi: 10.1007/s00204-019-02551-1. Epub 2019 Aug 23.


Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level.

Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA.

J Med Toxicol. 2019 Oct;15(4):295-298. doi: 10.1007/s13181-019-00727-w. Epub 2019 Aug 12.


Leveraging system sciences methods in clinical trial evaluation: An example concerning African American women diagnosed with breast cancer via the Patient Navigation in Medically Underserved Areas study.

Molina Y, Khanna A, Watson KS, Villines D, Bergeron N, Strayhorn S, Strahan D, Skwara A, Cronin M, Mohan P, Walton S, Wang T, Schneider JA, Calhoun EA.

Contemp Clin Trials Commun. 2019 Jul 19;15:100411. doi: 10.1016/j.conctc.2019.100411. eCollection 2019 Sep.


Unified Theory of Ultimate Hydrocarbon Recovery for Primary and Cyclic Injection Processes in Ultratight Reservoirs.

Cronin M, Emami-Meybodi H, Johns RT.

Sci Rep. 2019 Jul 24;9(1):10706. doi: 10.1038/s41598-019-47099-3.


Beyond Separate Emergence: A Systems View of Team Learning Climate.

Harvey JF, Leblanc PM, Cronin MA.

Front Psychol. 2019 Jul 3;10:1441. doi: 10.3389/fpsyg.2019.01441. eCollection 2019.


In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR.

Pawar G, Madden JC, Ebbrell D, Firman JW, Cronin MTD.

Front Pharmacol. 2019 Jun 11;10:561. doi: 10.3389/fphar.2019.00561. eCollection 2019. Review.


Quantitative magnetization transfer imaging of the human locus coeruleus.

Trujillo P, Petersen KJ, Cronin MJ, Lin YC, Kang H, Donahue MJ, Smith SA, Claassen DO.

Neuroimage. 2019 Oct 15;200:191-198. doi: 10.1016/j.neuroimage.2019.06.049. Epub 2019 Jun 21.


Unlocking the potential of in silico chemical safety assessment - A report on a cross-sector symposium on current opportunities and future challenges.

Cronin MTD, Madden JC, Yang C, Worth AP.

Comput Toxicol. 2019 May;10:38-43. doi: 10.1016/j.comtox.2018.12.006.


Genetic toxicology in silico protocol.

Hasselgren C, Ahlberg E, Akahori Y, Amberg A, Anger LT, Atienzar F, Auerbach S, Beilke L, Bellion P, Benigni R, Bercu J, Booth ED, Bower D, Brigo A, Cammerer Z, Cronin MTD, Crooks I, Cross KP, Custer L, Dobo K, Doktorova T, Faulkner D, Ford KA, Fortin MC, Frericks M, Gad-McDonald SE, Gellatly N, Gerets H, Gervais V, Glowienke S, Van Gompel J, Harvey JS, Hillegass J, Honma M, Hsieh JH, Hsu CW, Barton-Maclaren TS, Johnson C, Jolly R, Jones D, Kemper R, Kenyon MO, Kruhlak NL, Kulkarni SA, Kümmerer K, Leavitt P, Masten S, Miller S, Moudgal C, Muster W, Paulino A, Lo Piparo E, Powley M, Quigley DP, Reddy MV, Richarz AN, Schilter B, Snyder RD, Stavitskaya L, Stidl R, Szabo DT, Teasdale A, Tice RR, Trejo-Martin A, Vuorinen A, Wall BA, Watts P, White AT, Wichard J, Witt KL, Woolley A, Woolley D, Zwickl C, Myatt GJ.

Regul Toxicol Pharmacol. 2019 Oct;107:104403. doi: 10.1016/j.yrtph.2019.104403. Epub 2019 Jun 11.


Paediatric neck lumps: An approach for the primary physician

Smith A, Cronin M.

Aust J Gen Pract. 2019 May;48(5):289-293. doi: 10.31128/AJGP-09-18-4719.


Identification and description of the uncertainty, variability, bias and influence in quantitative structure-activity relationships (QSARs) for toxicity prediction.

Cronin MTD, Richarz AN, Schultz TW.

Regul Toxicol Pharmacol. 2019 Aug;106:90-104. doi: 10.1016/j.yrtph.2019.04.007. Epub 2019 Apr 24.


Conflict across representational gaps: Threats to and opportunities for improved communication.

Cronin MA, Weingart LR.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7642-7649. doi: 10.1073/pnas.1805866116. Epub 2019 Apr 15.


A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.

Desprez B, Birk B, Blaauboer B, Boobis A, Carmichael P, Cronin MTD, Curie R, Daston G, Hubesch B, Jennings P, Klaric M, Kroese D, Mahony C, Ouédraogo G, Piersma A, Richarz AN, Schwarz M, van Benthem J, van de Water B, Vinken M.

Toxicol In Vitro. 2019 Sep;59:44-50. doi: 10.1016/j.tiv.2019.04.005. Epub 2019 Apr 4.


Randomized Clinical Study Comparing Three Experimental Denture Adhesives and Fixodent® versus No Adhesive.

Axe A, Jain R, Varghese R, Mason S, DiLauro TS, Cronin M.

J Clin Dent. 2018 Dec;29(4):69-74.


Completion of the Updated Caprini Risk Assessment Model (2013 Version).

Cronin M, Dengler N, Krauss ES, Segal A, Wei N, Daly M, Mota F, Caprini JA.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619838052. doi: 10.1177/1076029619838052. Review.


Implementation and Validation of the 2013 Caprini Score for Risk Stratification of Arthroplasty Patients in the Prevention of Venous Thrombosis.

Krauss ES, Segal A, Cronin M, Dengler N, Lesser ML, Ahn S, Caprini JA.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619838066. doi: 10.1177/1076029619838066. Erratum in: Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619851962.


The effect of mobile personalised texting versus non-personalised texting on the caries risk of underprivileged adults: a randomised control trial.

Nishi M, Kelleher V, Cronin M, Allen F.

BMC Oral Health. 2019 Mar 12;19(1):44. doi: 10.1186/s12903-019-0729-1.


An RCT of atraumatic restorative treatment for older adults: 5 year results.

da Mata C, McKenna G, Anweigi L, Hayes M, Cronin M, Woods N, O'Mahony D, Allen PF.

J Dent. 2019 Apr;83:95-99. doi: 10.1016/j.jdent.2019.03.003. Epub 2019 Mar 9.


Response to 'Comment on 'Fascial layers influence the spread of injectate during ultrasound-guided infraclavicular brachial plexus block: a cadaver study' (Br J Anaesth 2019; 122: e54-5)'.

Brenner D, Mahon P, Iohom G, Cronin M, O'Flynn C, Shorten G.

Br J Anaesth. 2019 Mar;122(3):e56. doi: 10.1016/j.bja.2018.12.013. Epub 2019 Jan 23. No abstract available.


Self-Assembled Cationic β-Cyclodextrin Nanostructures for siRNA Delivery.

Singh RP, Hidalgo T, Cazade PA, Darcy R, Cronin MF, Dorin I, O'Driscoll CM, Thompson D.

Mol Pharm. 2019 Mar 4;16(3):1358-1366. doi: 10.1021/acs.molpharmaceut.8b01307. Epub 2019 Feb 19.


In vitro and in silico studies of the membrane permeability of natural flavonoids from Silybum marianum (L.) Gaertn. and their derivatives.

Diukendjieva A, Alov P, Tsakovska I, Pencheva T, Richarz A, Kren V, Cronin MTD, Pajeva I.

Phytomedicine. 2019 Feb;53:79-85. doi: 10.1016/j.phymed.2018.09.001. Epub 2018 Sep 5.


Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop.

Ellison CA, Blackburn KL, Carmichael PL, Clewell HJ 3rd, Cronin MTD, Desprez B, Escher SE, Ferguson SS, Grégoire S, Hewitt NJ, Hollnagel HM, Klaric M, Patel A, Salhi S, Schepky A, Schmitt BG, Wambaugh JF, Worth A.

Regul Toxicol Pharmacol. 2019 Apr;103:63-72. doi: 10.1016/j.yrtph.2019.01.016. Epub 2019 Jan 15. Review.


Chemoinformatic Consideration of Novel Psychoactive Substances: Compilation and Preliminary Analysis of a Categorised Dataset.

Firman JW, Belfield SJ, Chen G, Jackson M, Lam FH, Richmond C, Smith J, Steinmetz FP, Cronin MTD.

Mol Inform. 2019 Jan 17. doi: 10.1002/minf.201800142. [Epub ahead of print]


Spatial variation in a top marine predator's diet at two regionally distinct sites.

Gosch M, Cronin M, Rogan E, Hunt W, Luck C, Jessopp M.

PLoS One. 2019 Jan 2;14(1):e0209032. doi: 10.1371/journal.pone.0209032. eCollection 2019.


Optimizing drug discovery by Investigative Toxicology: Current and future trends.

Beilmann M, Boonen H, Czich A, Dear G, Hewitt P, Mow T, Newham P, Oinonen T, Pognan F, Roth A, Valentin JP, Van Goethem F, Weaver RJ, Birk B, Boyer S, Caloni F, Chen AE, Corvi R, Cronin MTD, Daneshian M, Ewart LC, Fitzgerald RE, Hamilton GA, Hartung T, Kangas JD, Kramer NI, Leist M, Marx U, Polak S, Rovida C, Testai E, Van der Water B, Vulto P, Steger-Hartmann T.

ALTEX. 2019;36(2):289-313. doi: 10.14573/altex.1808181. Epub 2018 Dec 20.


The Effect of BMI and Gender on Bleeding Events when Rivaroxaban Is Administered for Thromboprophylaxis Following Total Hip and Total Knee Arthroplasty.

Krauss ES, Cronin M, Dengler N, Simonson BG, Altner K, Daly M, Segal A.

Semin Thromb Hemost. 2019 Mar;45(2):180-186. doi: 10.1055/s-0038-1676319. Epub 2018 Dec 19.


Molecular fingerprint-derived similarity measures for toxicological read-across: Recommendations for optimal use.

Mellor CL, Marchese Robinson RL, Benigni R, Ebbrell D, Enoch SJ, Firman JW, Madden JC, Pawar G, Yang C, Cronin MTD.

Regul Toxicol Pharmacol. 2019 Feb;101:121-134. doi: 10.1016/j.yrtph.2018.11.002. Epub 2018 Nov 20.


A comparison of embalming fluids on the structures and properties of tissue in human cadavers.

Balta JY, Twomey M, Moloney F, Duggan O, Murphy KP, O'Connor OJ, Cronin M, Cryan JF, Maher MM, O'Mahony SM.

Anat Histol Embryol. 2019 Jan;48(1):64-73. doi: 10.1111/ahe.12412. Epub 2018 Nov 18.


Interpretation of QSAR Models: Mining Structural Patterns Taking into Account Molecular Context.

Matveieva M, Cronin MTD, Polishchuk P.

Mol Inform. 2019 Mar;38(3):e1800084. doi: 10.1002/minf.201800084. Epub 2018 Oct 22.


A critical review of adverse effects to the kidney: mechanisms, data sources, and in silico tools to assist prediction.

Pletz J, Enoch SJ, Jais DM, Mellor CL, Pawar G, Firman JW, Madden JC, Webb SD, Tagliati CA, Cronin MTD.

Expert Opin Drug Metab Toxicol. 2018 Dec;14(12):1225-1253. doi: 10.1080/17425255.2018.1539076. Epub 2018 Nov 25. Review.


Impact of oral rehabilitation on the quality of life of partially dentate elders in a randomised controlled clinical trial: 2 year follow-up.

McKenna G, Allen PF, Hayes M, DaMata C, Moore C, Cronin M.

PLoS One. 2018 Oct 11;13(10):e0203349. doi: 10.1371/journal.pone.0203349. eCollection 2018.


Involving young people in cyberbullying research: The implementation and evaluation of a rights-based approach.

Dennehy R, Cronin M, Arensman E.

Health Expect. 2019 Feb;22(1):54-64. doi: 10.1111/hex.12830. Epub 2018 Oct 10.


Fascial layers influence the spread of injectate during ultrasound-guided infraclavicular brachial plexus block: a cadaver study.

Brenner D, Mahon P, Iohom G, Cronin M, O'Flynn C, Shorten G.

Br J Anaesth. 2018 Oct;121(4):876-882. doi: 10.1016/j.bja.2018.04.043. Epub 2018 Jun 19.


Longitudinal data for magnetic susceptibility of normative human brain development and aging over the lifespan.

Zhang Y, Wei H, Cronin MJ, He N, Yan F, Liu C.

Data Brief. 2018 Jun 15;20:623-631. doi: 10.1016/j.dib.2018.06.005. eCollection 2018 Oct.


Program Director and Resident Perspectives on New Parent Leave in Dermatology Residency.

Gracey LE, Cronin M, Shinkai K, Mathes EF.

JAMA Dermatol. 2018 Oct 1;154(10):1222-1225. doi: 10.1001/jamadermatol.2018.2878. No abstract available.


PerLE: An "Open Source", ELearning Moodle-Based, Platform. A Study of University Undergraduates' Acceptance.

Servidio R, Cronin M.

Behav Sci (Basel). 2018 Jul 16;8(7). pii: E63. doi: 10.3390/bs8070063.


Impact of protease and amylase treatment on proteins and the product quality of a quinoa-based milk substitute.

Jeske S, Zannini E, Cronin MF, Arendt EK.

Food Funct. 2018 Jun 20;9(6):3500-3508. doi: 10.1039/c8fo00336j.


The Parallelogram Effect: The Association Between Central Band and Positive Ulnar Variance.

Orbay JL, Levaro-Pano F, Vernon LL, Cronin MH, Orbay JA, Tremols EJ.

J Hand Surg Am. 2018 Sep;43(9):827-832. doi: 10.1016/j.jhsa.2018.03.058. Epub 2018 May 24.


Widespread Skin Necrosis Secondary to Gemcitabine Therapy.

Zito PM, Gonzalez AM, Fox JD, Cronin M, Mackrides N, Kirsner RS, Nichols AJ.

J Drugs Dermatol. 2018 May 1;17(5):582-585.


In silico toxicology protocols.

Myatt GJ, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger LT, Aptula A, Auerbach S, Beilke L, Bellion P, Benigni R, Bercu J, Booth ED, Bower D, Brigo A, Burden N, Cammerer Z, Cronin MTD, Cross KP, Custer L, Dettwiler M, Dobo K, Ford KA, Fortin MC, Gad-McDonald SE, Gellatly N, Gervais V, Glover KP, Glowienke S, Van Gompel J, Gutsell S, Hardy B, Harvey JS, Hillegass J, Honma M, Hsieh JH, Hsu CW, Hughes K, Johnson C, Jolly R, Jones D, Kemper R, Kenyon MO, Kim MT, Kruhlak NL, Kulkarni SA, Kümmerer K, Leavitt P, Majer B, Masten S, Miller S, Moser J, Mumtaz M, Muster W, Neilson L, Oprea TI, Patlewicz G, Paulino A, Lo Piparo E, Powley M, Quigley DP, Reddy MV, Richarz AN, Ruiz P, Schilter B, Serafimova R, Simpson W, Stavitskaya L, Stidl R, Suarez-Rodriguez D, Szabo DT, Teasdale A, Trejo-Martin A, Valentin JP, Vuorinen A, Wall BA, Watts P, White AT, Wichard J, Witt KL, Woolley A, Woolley D, Zwickl C, Hasselgren C.

Regul Toxicol Pharmacol. 2018 Jul;96:1-17. doi: 10.1016/j.yrtph.2018.04.014. Epub 2018 Apr 17.


Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial.

Brady P, Iohom G, O'Halloran KD, McCreary C, Cronin M.

BDJ Open. 2017 Oct 13;3:17019. doi: 10.1038/bdjopen.2017.19. eCollection 2017.


Assessment and Reproducibility of Quantitative Structure-Activity Relationship Models by the Nonexpert.

Patel M, Chilton ML, Sartini A, Gibson L, Barber C, Covey-Crump L, Przybylak KR, Cronin MTD, Madden JC.

J Chem Inf Model. 2018 Mar 26;58(3):673-682. doi: 10.1021/acs.jcim.7b00523. Epub 2018 Feb 22.


Quantitative susceptibility mapping (QSM) as a means to monitor cerebral hematoma treatment.

Zhang Y, Wei H, Sun Y, Cronin MJ, He N, Xu J, Zhou Y, Liu C.

J Magn Reson Imaging. 2018 Oct;48(4):907-915. doi: 10.1002/jmri.25957. Epub 2018 Jan 30.


Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

Hemingway H, Asselbergs FW, Danesh J, Dobson R, Maniadakis N, Maggioni A, van Thiel GJM, Cronin M, Brobert G, Vardas P, Anker SD, Grobbee DE, Denaxas S; Innovative Medicines Initiative 2nd programme, Big Data for Better Outcomes, BigData@Heart Consortium of 20 academic and industry partners including ESC.

Eur Heart J. 2018 Apr 21;39(16):1481-1495. doi: 10.1093/eurheartj/ehx487.


Longitudinal atlas for normative human brain development and aging over the lifespan using quantitative susceptibility mapping.

Zhang Y, Wei H, Cronin MJ, He N, Yan F, Liu C.

Neuroimage. 2018 May 1;171:176-189. doi: 10.1016/j.neuroimage.2018.01.008. Epub 2018 Jan 8.

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