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Items: 1 to 50 of 107

1.

Elevated transcription of the gene QSOX1 encoding quiescin Q6 sulfhydryl oxidase 1 in breast cancer.

Soloviev M, Esteves MP, Amiri F, Crompton MR, Rider CC.

PLoS One. 2013;8(2):e57327. doi: 10.1371/journal.pone.0057327. Epub 2013 Feb 27.

2.

Breast tumor kinase (Brk/PTK6) plays a role in the differentiation of primary keratinocytes.

Tupper J, Crompton MR, Harvey AJ.

Arch Dermatol Res. 2011 May;303(4):293-7. doi: 10.1007/s00403-010-1118-4. Epub 2011 Jan 15.

3.

Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage.

Harvey AJ, Pennington CJ, Porter S, Burmi RS, Edwards DR, Court W, Eccles SA, Crompton MR.

Am J Pathol. 2009 Sep;175(3):1226-34. doi: 10.2353/ajpath.2009.080811. Epub 2009 Aug 6.

4.

RNAi-mediated knockdown of dystrophin expression in adult mice does not lead to overt muscular dystrophy pathology.

Ghahramani Seno MM, Graham IR, Athanasopoulos T, Trollet C, Pohlschmidt M, Crompton MR, Dickson G.

Hum Mol Genet. 2008 Sep 1;17(17):2622-32. doi: 10.1093/hmg/ddn162. Epub 2008 May 28.

PMID:
18511456
6.
7.

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

Kasprzycka M, Majewski M, Wang ZJ, Ptasznik A, Wysocka M, Zhang Q, Marzec M, Gimotty P, Crompton MR, Wasik MA.

Am J Pathol. 2006 May;168(5):1631-41.

8.

RNA interference targeting of Bcr-Abl increases chronic myeloid leukemia cell killing by 17-allylamino-17-demethoxygeldanamycin.

Withey JM, Harvey AJ, Crompton MR.

Leuk Res. 2006 May;30(5):553-60. Epub 2005 Nov 2.

PMID:
16260034
9.

Targeting primary human leukaemia cells with RNA interference: Bcr-Abl targeting inhibits myeloid progenitor self-renewal in chronic myeloid leukaemia cells.

Withey JM, Marley SB, Kaeda J, Harvey AJ, Crompton MR, Gordon MY.

Br J Haematol. 2005 May;129(3):377-80.

PMID:
15842662
10.

Comparison of neuroplastin and synaptic marker protein expression in acute and cultured organotypic hippocampal slices from rat.

Buckby LE, Mummery R, Crompton MR, Beesley PW, Empson RM.

Brain Res Dev Brain Res. 2004 May 19;150(1):1-7.

PMID:
15126032
11.

The Brk protein tyrosine kinase as a therapeutic target in cancer: opportunities and challenges.

Harvey AJ, Crompton MR.

Anticancer Drugs. 2004 Feb;15(2):107-11. Review.

PMID:
15075665
15.

A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK.

Mitchell PJ, Sara EA, Crompton MR.

Oncogene. 2000 Aug 31;19(37):4273-82.

16.

Cytotoxic response of ovarian cancer cell lines to IFN-gamma is associated with sustained induction of IRF-1 and p21 mRNA.

Burke F, Smith PD, Crompton MR, Upton C, Balkwill FR.

Br J Cancer. 1999 Jun;80(8):1236-44.

17.

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions.

Smith PD, Crossland S, Parker G, Osin P, Brooks L, Waller J, Philp E, Crompton MR, Gusterson BA, Allday MJ, Crook T.

Oncogene. 1999 Apr 15;18(15):2451-9.

18.

Functional consequences of cyclin D1 overexpression in human mammary luminal epithelial cells.

Kamalati T, Davies D, Titley J, Crompton MR.

Clin Exp Metastasis. 1998 Jul;16(5):415-26.

PMID:
10091937
19.

p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours.

Crook T, Brooks LA, Crossland S, Osin P, Barker KT, Waller J, Philp E, Smith PD, Yulug I, Peto J, Parker G, Allday MJ, Crompton MR, Gusterson BA.

Oncogene. 1998 Oct 1;17(13):1681-9.

21.

Expression of v-src in mammary epithelial cells induces transcription via STAT3.

Smith PD, Crompton MR.

Biochem J. 1998 Apr 15;331 ( Pt 2):381-5.

22.

[3H] imipramine binding in brain samples from depressed suicides and controls: 5-HT uptake sites compared with sites defined by desmethylimipramine.

Lawrence KM, Kanagasundaram M, Lowther S, Katona CL, Crompton MR, Horton RW.

J Affect Disord. 1998 Jan;47(1-3):105-12.

PMID:
9476750
23.

Dopamine uptake sites, labelled with [3H]GBR12935, in brain samples from depressed suicides and controls.

Bowden C, Cheetham SC, Lowther S, Katona CL, Crompton MR, Horton RW.

Eur Neuropsychopharmacol. 1997 Nov;7(4):247-52.

PMID:
9443655
24.

Nuclear location and cell cycle regulation of the BRCA2 protein.

Bertwistle D, Swift S, Marston NJ, Jackson LE, Crossland S, Crompton MR, Marshall CJ, Ashworth A.

Cancer Res. 1997 Dec 15;57(24):5485-8.

25.

Corticotropin-releasing factor binding sites in cortex of depressed suicides.

Hucks D, Lowther S, Crompton MR, Katona CL, Horton RW.

Psychopharmacology (Berl). 1997 Nov;134(2):174-8.

PMID:
9399381
26.

Reduced dopamine turnover in the basal ganglia of depressed suicides.

Bowden C, Cheetham SC, Lowther S, Katona CL, Crompton MR, Horton RW.

Brain Res. 1997 Sep 19;769(1):135-40.

PMID:
9374281
27.

Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk.

Mitchell PJ, Barker KT, Shipley J, Crompton MR.

Oncogene. 1997 Sep 18;15(12):1497-502. Erratum in: Oncogene 1998 Jul 9;17(1):129.

28.

p53 mutations in BRCA1-associated familial breast cancer.

Crook T, Crossland S, Crompton MR, Osin P, Gusterson BA.

Lancet. 1997 Aug 30;350(9078):638-9. No abstract available.

PMID:
9288052
29.

BRK tyrosine kinase expression in a high proportion of human breast carcinomas.

Barker KT, Jackson LE, Crompton MR.

Oncogene. 1997 Aug 14;15(7):799-805.

30.

5-HT1D and 5-HT1E/1F binding sites in depressed suicides: increased 5-HT1D binding in globus pallidus but not cortex.

Lowther S, Katona CL, Crompton MR, Horton RW.

Mol Psychiatry. 1997 Jul;2(4):314-21.

31.

Brain [3H]cAMP binding sites are unaltered in depressed suicides, but decreased by antidepressants.

Lowther S, Katona CL, Crompton MR, Horton RW.

Brain Res. 1997 May 30;758(1-2):223-8.

PMID:
9203552
32.

Brain alpha-adrenoceptors in depressed suicides.

De Paermentier F, Mauger JM, Lowther S, Crompton MR, Katona CL, Horton RW.

Brain Res. 1997 May 16;757(1):60-8.

PMID:
9200499
33.

Brain 5-hydroxytryptamine uptake sites labeled with [3H]paroxetine in antidepressant drug-treated depressed suicide victims and controls.

Lawrence KM, De Paermentier F, Lowther S, Crompton MR, Katona CL, Horton RW.

J Psychiatry Neurosci. 1997 May;22(3):185-91.

34.

Dopamine D1 and D2 receptor binding sites in brain samples from depressed suicides and controls.

Bowden C, Theodorou AE, Cheetham SC, Lowther S, Katona CL, Crompton MR, Horton RW.

Brain Res. 1997 Mar 28;752(1-2):227-33.

PMID:
9106461
35.

5-HT1A receptor binding sites in post-mortem brain samples from depressed suicides and controls.

Lowther S, De Paermentier F, Cheetham SC, Crompton MR, Katona CL, Horton RW.

J Affect Disord. 1997 Feb;42(2-3):199-207.

PMID:
9105961
36.

Beta-adrenoceptors in human pineal glands are unaltered in depressed suicides.

De Paermentier F, Lowther S, Crompton MR, Katona CL, Horton RW.

J Psychopharmacol. 1997;11(4):295-9.

PMID:
9443516
37.

ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins.

Smith PD, Barker KT, Wang J, Lu YJ, Shipley J, Crompton MR.

Biochem Biophys Res Commun. 1996 Dec 13;229(2):402-11.

PMID:
8954911
38.

GTP gamma S and forskolin-stimulated adenylyl cyclase activity in post-mortem brain from depressed suicides and controls.

Lowther S, Crompton MR, Katona CL, Horton RW.

Mol Psychiatry. 1996 Dec;1(6):470-7.

PMID:
9154249
39.

Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor.

Kamalati T, Jolin HE, Mitchell PJ, Barker KT, Jackson LE, Dean CJ, Page MJ, Gusterson BA, Crompton MR.

J Biol Chem. 1996 Nov 29;271(48):30956-63.

40.

Molecular cloning and characterization of PTP pi, a novel receptor-like protein-tyrosine phosphatase.

Crossland S, Smith PD, Crompton MR.

Biochem J. 1996 Oct 1;319 ( Pt 1):249-54.

41.

Expression of the receptor protein tyrosine kinase myk-1/htk in normal and malignant mammary epithelium.

Berclaz G, Andres AC, Albrecht D, Dreher E, Ziemiecki A, Gusterson BA, Crompton MR.

Biochem Biophys Res Commun. 1996 Sep 24;226(3):869-75.

PMID:
8831703
42.

Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains.

Smith AL, Mitchell PJ, Shipley J, Gusterson BA, Rogers MV, Crompton MR.

Biochem Biophys Res Commun. 1995 Apr 26;209(3):959-65.

PMID:
7733990
43.

Expression patterns of the novel receptor-like tyrosine kinase, DDR, in human breast tumours.

Barker KT, Martindale JE, Mitchell PJ, Kamalati T, Page MJ, Phippard DJ, Dale TC, Gusterson BA, Crompton MR.

Oncogene. 1995 Feb 2;10(3):569-75.

PMID:
7845682
44.

Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours.

Mitchell PJ, Barker KT, Martindale JE, Kamalati T, Lowe PN, Page MJ, Gusterson BA, Crompton MR.

Oncogene. 1994 Aug;9(8):2383-90.

PMID:
8036022
45.

Brain 5-HT2 receptors in suicide victims: violence of death, depression and effects of antidepressant treatment.

Lowther S, De Paermentier F, Crompton MR, Katona CL, Horton RW.

Brain Res. 1994 Apr 11;642(1-2):281-9.

PMID:
8032889
46.

NMDA glutamatergic receptors, labelled with [3H]MK-801, in brain samples from drug-free depressed suicides.

Holemans S, De Paermentier F, Horton RW, Crompton MR, Katona CL, Maloteaux JM.

Brain Res. 1993 Jul 9;616(1-2):138-43.

PMID:
8358605
47.

Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells.

Crompton MR, Bartlett TJ, MacGregor AD, Manfioletti G, Buratti E, Giancotti V, Goodwin GH.

Nucleic Acids Res. 1992 Nov 11;20(21):5661-7.

48.

The distribution of 5-HT1D and 5-HT1E binding sites in human brain.

Lowther S, De Paermentier F, Crompton MR, Horton RW.

Eur J Pharmacol. 1992 Nov 3;222(1):137-42.

PMID:
1468490
49.

Rapid characterisation of differentially expressed members of multigene families.

Crompton MR, Bartlett TJ, Goodwin GH.

Nucleic Acids Res. 1992 Aug 11;20(15):4107-8. No abstract available.

50.

Molecular cloning of the chicken SCL cDNA.

Goodwin G, MacGregor A, Zhu J, Crompton MR.

Nucleic Acids Res. 1992 Jan 25;20(2):368. No abstract available.

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