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Items: 1 to 50 of 93

1.

Biological characterization of a heterodimer-selective retinoid X receptor modulator: potential benefits for the treatment of type 2 diabetes.

Leibowitz MD, Ardecky RJ, Boehm MF, Broderick CL, Carfagna MA, Crombie DL, D'Arrigo J, Etgen GJ, Faul MM, Grese TA, Havel H, Hein NI, Heyman RA, Jolley D, Klausing K, Liu S, Mais DE, Mapes CM, Marschke KB, Michellys PY, Montrose-Rafizadeh C, Ogilvie KM, Pascual B, Rungta D, Tyhonas JS, Urcan MS, Wardlow M, Yumibe N, Reifel-Miller A.

Endocrinology. 2006 Feb;147(2):1044-53. Epub 2005 Nov 3.

PMID:
16269450
2.

A role for guanylate cyclase C in acid-stimulated duodenal mucosal bicarbonate secretion.

Rao SP, Sellers Z, Crombie DL, Hogan DL, Mann EA, Childs D, Keely S, Sheil-Puopolo M, Giannella RA, Barrett KE, Isenberg JI, Pratha VS.

Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G95-G101. Epub 2003 Jul 24.

3.

Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes.

Michellys PY, Ardecky RJ, Chen JH, Crombie DL, Etgen GJ, Faul MM, Faulkner AL, Grese TA, Heyman RA, Karanewsky DS, Klausing K, Leibowitz MD, Liu S, Mais DA, Mapes CM, Marschke KB, Reifel-Miller A, Ogilvie KM, Rungta D, Thompson AW, Tyhonas JS, Boehm MF.

J Med Chem. 2003 Jun 19;46(13):2683-96.

PMID:
12801232
4.

Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the Zucker diabetic fatty rat.

Dana SL, Hoener PA, Bilakovics JM, Crombie DL, Ogilvie KM, Kauffman RF, Mukherjee R, Paterniti JR Jr.

Metabolism. 2001 Aug;50(8):963-71.

PMID:
11474486
5.

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.

Singh Ahuja H, Liu S, Crombie DL, Boehm M, Leibowitz MD, Heyman RA, Depre C, Nagy L, Tontonoz P, Davies PJ.

Mol Pharmacol. 2001 Apr;59(4):765-73.

PMID:
11259621
6.

Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity.

Davies PJ, Berry SA, Shipley GL, Eckel RH, Hennuyer N, Crombie DL, Ogilvie KM, Peinado-Onsurbe J, Fievet C, Leibowitz MD, Heyman RA, Auwerx J.

Mol Pharmacol. 2001 Feb;59(2):170-6.

PMID:
11160850
7.

Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats.

Liu YL, Sennitt MV, Hislop DC, Crombie DL, Heyman RA, Cawthorne MA.

Int J Obes Relat Metab Disord. 2000 Aug;24(8):997-1004.

PMID:
10951538
8.

Relation between high temperature and mortality.

Crombie DL, Fleming DM, Cross KW.

J Epidemiol Community Health. 1999 Sep;53(9):591. No abstract available.

9.

Discovery and preliminary SAR studies of a novel, nonsteroidal progesterone receptor antagonist pharmacophore.

Pooley CL, Edwards JP, Goldman ME, Wang MW, Marschke KB, Crombie DL, Jones TK.

J Med Chem. 1998 Aug 27;41(18):3461-6.

PMID:
9719599
10.

Screening for diabetes.

Pike LA, Crombie DL.

Br J Gen Pract. 1997 Nov;47(424):751-2. No abstract available.

11.

Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice.

Hogan DL, Crombie DL, Isenberg JI, Svendsen P, Schaffalitzky de Muckadell OB, Ainsworth MA.

Gastroenterology. 1997 Aug;113(2):533-41.

PMID:
9247473
12.

CFTR mediates cAMP- and Ca2+-activated duodenal epithelial HCO3- secretion.

Hogan DL, Crombie DL, Isenberg JI, Svendsen P, Schaffalitzky de Muckadell OB, Ainsworth MA.

Am J Physiol. 1997 Apr;272(4 Pt 1):G872-8.

PMID:
9142920
13.

Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.

Mukherjee R, Davies PJ, Crombie DL, Bischoff ED, Cesario RM, Jow L, Hamann LG, Boehm MF, Mondon CE, Nadzan AM, Paterniti JR Jr, Heyman RA.

Nature. 1997 Mar 27;386(6623):407-10.

PMID:
9121558
14.

Anti-idiotypic immunization against progesterone.

Wang MW, Crombie DL, Hayes JS, Taussig MJ, Heap RB.

Am J Reprod Immunol. 1995 Dec;34(6):386-8. No abstract available.

PMID:
8607945
15.

Progesterone and oestrogen receptors in the decidualized mouse uterus and effects of different types of anti-progesterone treatment.

Parandoosh Z, Crombie DL, Tetzke TA, Hayes JS, Heap RB, Wang MW.

J Reprod Fertil. 1995 Nov;105(2):215-20.

PMID:
8568763
16.

Anti-progesterone effects on maternal recognition and behaviour imprinted during first pregnancy in mice.

Crombie DL, Hayes JS, Heap RB, Wang MW.

J Endocrinol. 1995 Nov;147(2):331-7.

PMID:
7490563
17.

Concurrence of monthly variations of mortality related to underlying cause in Europe.

Crombie DL, Fleming DM, Cross KW, Lancashire RJ.

J Epidemiol Community Health. 1995 Aug;49(4):373-8.

18.

Trends in sudden infant death. Infant respiratory death rates mirror sudden infant deaths.

Crombie DL, Cross KW, Fleming DM.

BMJ. 1995 Jun 17;310(6994):1603. No abstract available.

19.

Aberrant maternal behaviour in mice treated with a progesterone receptor antagonist during pregnancy.

Wang MW, Crombie DL, Hayes JS, Heap RB.

J Endocrinol. 1995 May;145(2):371-7.

PMID:
7616171
20.

Anti-progesterone antibody administration and the impairment of postpartum maternal care in mice.

Wang MW, Crombie DL, Mais DE, Hayes JS, Heap RB.

J Endocrinol. 1995 May;145(2):363-9.

PMID:
7616170
21.

Creatine kinase activity as an indicator of unopposed estrogen action in the mouse uterus associated with anti-progesterone treatment.

Crombie DL, Mukherjee R, McDonnell DP, Hayes JS, Wang MW.

J Steroid Biochem Mol Biol. 1994 Jun;49(2-3):123-9.

PMID:
8031708
22.

Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.

Hagey LR, Crombie DL, Espinosa E, Carey MC, Igimi H, Hofmann AF.

J Lipid Res. 1993 Nov;34(11):1911-7.

24.

Gastric acid suppression is greater during intravenous ranitidine infusion versus bolus injections of famotidine.

Hogan DL, McQuaid KR, Koss MA, Crombie DL, Hunter S, Metz C, Euler AR, Isenberg JI.

Aliment Pharmacol Ther. 1993 Oct;7(5):537-41.

PMID:
8280822
25.

Negative feedback regulation of the ileal bile acid transport system in rodents.

Lillienau J, Crombie DL, Munoz J, Longmire-Cook SJ, Hagey LR, Hofmann AF.

Gastroenterology. 1993 Jan;104(1):38-46.

PMID:
8419260
26.

Acute effects of topical methyl tert-butyl ether or ethyl propionate on gallbladder histology in animals: a comparison of two solvents for contact dissolution of cholesterol gallstones.

Esch O, Spinosa JC, Hamilton RL, Crombie DL, Schteingart CD, Rondinone JF, D'Agostino HB, Lillienau J, Hofmann AF.

Hepatology. 1992 Oct;16(4):984-91.

PMID:
1398506
27.

The problem of diagnostic variability in general practice.

Crombie DL, Cross KW, Fleming DM.

J Epidemiol Community Health. 1992 Aug;46(4):447-54.

28.

Annual and seasonal variation in the incidence of common diseases.

Fleming DM, Norbury CA, Crombie DL.

Occas Pap R Coll Gen Pract. 1991 Oct;(53):1-24. No abstract available.

29.

Changes in practice morbidity between the 1970 and 1981 national morbidity surveys.

Fleming DM, Cross KW, Olmos LG, Crombie DL.

Br J Gen Pract. 1991 May;41(346):202-6.

30.
31.

Observations on the influenza epidemic of November/December 1989.

Fleming DM, Crombie DL, Norbury CA, Cross KW.

Br J Gen Pract. 1990 Dec;40(341):495-7.

32.

Birmingham diabetes survey.

Crombie DL.

J R Coll Gen Pract. 1989 Aug;39(325):350. No abstract available.

33.

Practice activity analysis.

Crombie DL, Fleming DM.

J R Coll Gen Pract Occas Pap. 1988 Dec;(41):1-47. No abstract available.

34.
35.

General practitioner referrals to hospital: the financial implications of variability.

Crombie DL, Fleming DM.

Health Trends. 1988 May;20(2):53-6.

PMID:
10312605
36.

Prognosis in adult asthma: a national study.

Markowe HL, Bulpitt CJ, Shipley MJ, Rose G, Crombie DL, Fleming DM.

Br Med J (Clin Res Ed). 1987 Oct 17;295(6604):949-52.

37.

Prevalence of asthma and hay fever in England and Wales.

Fleming DM, Crombie DL.

Br Med J (Clin Res Ed). 1987 Jan 31;294(6567):279-83.

38.

The third national study of morbidity statistics from general practice.

Crombie DL, Fleming DM.

J R Coll Gen Pract. 1986 Feb;36(283):51-2. No abstract available.

39.

Comparison of Second National Morbidity Study and General Household Survey 1970-71.

Crombie DL, Fleming DM.

Health Trends. 1986 Feb;18(1):15-8.

PMID:
10276131
40.

Malignant hypertension in general practice.

Bulpitt CJ, Bulpitt PF, Clark PB, Crombie DL, Lambert P, Dollery CT.

J R Coll Gen Pract. 1985 Oct;35(279):471-5.

41.
42.

Social class and health status. Inequality or difference. McConaghey memorial lecture.

Crombie DL.

J R Coll Gen Pract Occas Pap. 1984 Apr;(25):1-15. No abstract available.

43.

Mumps surveillance in England and Wales 1962-81.

Galbraith NS, Young SE, Pusey JJ, Crombie DL, Sparks JP.

Lancet. 1984 Jan 14;1(8368):91-4.

PMID:
6140434
44.

Quality of care in general practice.

Crombie DL, Fleming DM.

J R Coll Gen Pract. 1983 Nov;33(256):746-7. No abstract available.

45.

Immunization procedures in Europe.

Crombie DL.

Health Trends. 1983 Nov;15(4):86-90. No abstract available.

PMID:
10270088
46.

Whooping cough: what proportion of cases is notified in an epidemic.

Crombie DL.

Br Med J (Clin Res Ed). 1983 Sep 10;287(6394):760-1. No abstract available.

47.

Inter-practice variability in multipractice studies.

Crombie DL.

Scand J Prim Health Care. 1983;1(2):51-3. No abstract available.

PMID:
6545029
48.

Reported illness and change of residence.

Goodman M, Crombie DL.

J R Coll Gen Pract. 1982;32(243):609-13.

49.

Debendox in early pregnancy and fetal malformation.

Fleming DM, Knox JD, Crombie DL.

Br Med J (Clin Res Ed). 1981 Jul 11;283(6284):99-101.

50.

Monitoring of psychotropic drug prescribing in general practice.

Crombie DL.

Br Med J. 1979 Dec 1;2(6202):1436. No abstract available.

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