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Items: 17


Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media.

Daniszewski M, Nguyen Q, Chy HS, Singh V, Crombie DE, Kulkarni T, Liang HH, Sivakumaran P, Lidgerwood GE, Hernández D, Conquest A, Rooney LA, Chevalier S, Andersen SB, Senabouth A, Vickers JC, Mackey DA, Craig JE, Laslett AL, Hewitt AW, Powell JE, Pébay A.

iScience. 2018 Sep 28;7:30-39. doi: 10.1016/j.isci.2018.08.016. Epub 2018 Aug 23.


Single cell RNA sequencing of stem cell-derived retinal ganglion cells.

Daniszewski M, Senabouth A, Nguyen QH, Crombie DE, Lukowski SW, Kulkarni T, Sluch VM, Jabbari JS, Chamling X, Zack DJ, Pébay A, Powell JE, Hewitt AW.

Sci Data. 2018 Feb 13;5:180013. doi: 10.1038/sdata.2018.13.


Automated Cell Culture Systems and Their Applications to Human Pluripotent Stem Cell Studies.

Daniszewski M, Crombie DE, Henderson R, Liang HH, Wong RCB, Hewitt AW, Pébay A.

SLAS Technol. 2018 Aug;23(4):315-325. doi: 10.1177/2472630317712220. Epub 2017 Jun 2. Review.


Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency.

Crombie DE, Curl CL, Raaijmakers AJ, Sivakumaran P, Kulkarni T, Wong RC, Minami I, Evans-Galea MV, Lim SY, Delbridge L, Corben LA, Dottori M, Nakatsuji N, Trounce IA, Hewitt AW, Delatycki MB, Pera MF, Pébay A.

Aging (Albany NY). 2017 May 30;9(5):1440-1452. doi: 10.18632/aging.101247.


Development of a Modular Automated System for Maintenance and Differentiation of Adherent Human Pluripotent Stem Cells.

Crombie DE, Daniszewski M, Liang HH, Kulkarni T, Li F, Lidgerwood GE, Conquest A, Hernández D, Hung SS, Gill KP, De Smit E, Kearns LS, Clarke L, Sluch VM, Chamling X, Zack DJ, Wong RCB, Hewitt AW, Pébay A.

SLAS Discov. 2017 Sep;22(8):1016-1025. doi: 10.1177/2472555217696797. Epub 2017 Mar 13.


Enriched retinal ganglion cells derived from human embryonic stem cells.

Gill KP, Hung SS, Sharov A, Lo CY, Needham K, Lidgerwood GE, Jackson S, Crombie DE, Nayagam BA, Cook AL, Hewitt AW, Pébay A, Wong RC.

Sci Rep. 2016 Aug 10;6:30552. doi: 10.1038/srep30552.


Using human pluripotent stem cells to study Friedreich ataxia cardiomyopathy.

Crombie DE, Pera MF, Delatycki MB, Pébay A.

Int J Cardiol. 2016 Jun 1;212:37-43. doi: 10.1016/j.ijcard.2016.03.040. Epub 2016 Mar 21. Review.


Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells.

Hernández D, Millard R, Sivakumaran P, Wong RC, Crombie DE, Hewitt AW, Liang H, Hung SS, Pébay A, Shepherd RK, Dusting GJ, Lim SY.

Stem Cells Int. 2016;2016:1718041. doi: 10.1155/2016/1718041. Epub 2015 Dec 14.


Defined Medium Conditions for the Induction and Expansion of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.

Lidgerwood GE, Lim SY, Crombie DE, Ali R, Gill KP, Hernández D, Kie J, Conquest A, Waugh HS, Wong RC, Liang HH, Hewitt AW, Davidson KC, Pébay A.

Stem Cell Rev Rep. 2016 Apr;12(2):179-88. doi: 10.1007/s12015-015-9636-2.


Characterization of the retinal pigment epithelium in Friedreich ataxia.

Crombie DE, Van Bergen N, Davidson KC, Anjomani Virmouni S, Mckelvie PA, Chrysostomou V, Conquest A, Corben LA, Pook MA, Kulkarni T, Trounce IA, Pera MF, Delatycki MB, Pébay A.

Biochem Biophys Rep. 2015 Sep 11;4:141-147. doi: 10.1016/j.bbrep.2015.09.003. eCollection 2015 Dec.


Enhancing Human Cardiomyocyte Differentiation from Induced Pluripotent Stem Cells with Trichostatin A.

Lim SY, Sivakumaran P, Crombie DE, Dusting GJ, Pébay A, Dilley RJ.

Methods Mol Biol. 2016;1357:415-21. doi: 10.1007/7651_2014_160.


Trichostatin A enhances differentiation of human induced pluripotent stem cells to cardiogenic cells for cardiac tissue engineering.

Lim SY, Sivakumaran P, Crombie DE, Dusting GJ, Pébay A, Dilley RJ.

Stem Cells Transl Med. 2013 Sep;2(9):715-25. doi: 10.5966/sctm.2012-0161. Epub 2013 Jul 24.


Rho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acid.

Frisca F, Crombie DE, Dottori M, Goldshmit Y, Pébay A.

J Lipid Res. 2013 May;54(5):1192-206. doi: 10.1194/jlr.M032284. Epub 2013 Mar 4.


Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro.

Crombie DE, Turer M, Zuasti BB, Wood B, McNaughton D, Nandakumar KS, Holmdahl R, Van Damme MP, Rowley MJ.

Arthritis Res Ther. 2005;7(5):R927-37. Epub 2005 Jun 6.


Arthritogenic anti-type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells.

Amirahmadi SF, Whittingham S, Crombie DE, Nandakumar KS, Holmdahl R, Mackay IR, van Damme MP, Rowley MJ.

Arthritis Rheum. 2005 Jun;52(6):1897-906.


Images of interest. Hepatobiliary and pancreatic: Liver histopathology: Fourier transform infrared microspectroscopic imaging for objective and quantifiable assessment of liver biopsies.

Crombie DE, Mackay IR, Wood BR, McNaughton D, Rowley MJ.

J Gastroenterol Hepatol. 2005 Mar;20(3):485. Review. No abstract available.


An arthritogenic monoclonal antibody to type II collagen, CII-C1, impairs cartilage formation by cultured chondrocytes.

Amirahmadi SF, Pho MH, Gray RE, Crombie DE, Whittingham SF, Zuasti BB, Van Damme MP, Rowley MJ.

Immunol Cell Biol. 2004 Aug;82(4):427-34.


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