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Items: 1 to 50 of 96

1.

Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn's Disease.

Turpin W, Espin-Garcia O, Bedrani L, Madsen K, Meddings JB, Raygoza Garay JA, Silverberg MS, Smith MI, Griffiths AM, Moayyedi P, Marshall JK, Mack D, Seidman EG, Ropeleski M, Feagan BG, Jacobson K, Turner D, Walters T, Paterson AD; CCC GEM Project Research Consortium , Xu W, Croitoru K.

Inflamm Bowel Dis. 2019 Jun 28. pii: izz116. doi: 10.1093/ibd/izz116. [Epub ahead of print]

PMID:
31251335
2.

Mucosa-Associated Microbiota in Ileoanal Pouches May Contribute to Clinical Symptoms, Particularly Stool Frequency, Independent of Endoscopic Disease Activity.

Turpin W, Kelly O, Borowski K, Boland K, Tyler A, Cohen Z, Croitoru K, Silverberg MS.

Clin Transl Gastroenterol. 2019 May 22;10(5):1-7. doi: 10.14309/ctg.0000000000000038.

PMID:
31117112
3.

Challenges in IBD Research: Environmental Triggers.

Ho SM, Lewis JD, Mayer EA, Plevy SE, Chuang E, Rappaport SM, Croitoru K, Korzenik JR, Krischer J, Hyams JS, Judson R, Kellis M, Jerrett M, Miller GW, Grant ML, Shtraizent N, Honig G, Hurtado-Lorenzo A, Wu GD.

Inflamm Bowel Dis. 2019 May 16;25(Supplement_2):S13-S23. doi: 10.1093/ibd/izz076.

PMID:
31095702
4.

Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models.

Robertson SJ, Lemire P, Maughan H, Goethel A, Turpin W, Bedrani L, Guttman DS, Croitoru K, Girardin SE, Philpott DJ.

Cell Rep. 2019 May 7;27(6):1910-1919.e2. doi: 10.1016/j.celrep.2019.04.023.

5.

A rare presentation of hypovolemic shock secondary to Whipple's disease.

Tandon P, Huang V, Jaffer N, Kirsch R, Croitoru K.

Eur J Gastroenterol Hepatol. 2019 May;31(5):642-645. doi: 10.1097/MEG.0000000000001363.

PMID:
30694911
6.

A finite mixture model for X-chromosome association with an emphasis on microbiome data analysis.

Espin-Garcia O, Croitoru K, Xu W.

Genet Epidemiol. 2019 Jun;43(4):427-439. doi: 10.1002/gepi.22190. Epub 2019 Jan 18.

PMID:
30657195
7.

Nod2 influences microbial resilience and susceptibility to colitis following antibiotic exposure.

Goethel A, Turpin W, Rouquier S, Zanello G, Robertson SJ, Streutker CJ, Philpott DJ, Croitoru K.

Mucosal Immunol. 2019 May;12(3):720-732. doi: 10.1038/s41385-018-0128-y. Epub 2019 Jan 16.

PMID:
30651577
8.

Generational Patterns of Asthma Incidence among Immigrants to Canada over Two Decades. A Population-based Cohort Study.

Radhakrishnan D, Guttmann A, To T, Reisman JJ, Knight BD, Mojaverian N, Manuel DG, Gommerman JL, Croitoru K, Benchimol EI.

Ann Am Thorac Soc. 2019 Feb;16(2):248-257. doi: 10.1513/AnnalsATS.201803-187OC.

PMID:
30395726
9.

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.

Wang J, Kurilshikov A, Radjabzadeh D, Turpin W, Croitoru K, Bonder MJ, Jackson MA, Medina-Gomez C, Frost F, Homuth G, Rühlemann M, Hughes D, Kim HN; MiBioGen Consortium Initiative, Spector TD, Bell JT, Steves CJ, Timpson N, Franke A, Wijmenga C, Meyer K, Kacprowski T, Franke L, Paterson AD, Raes J, Kraaij R, Zhernakova A.

Microbiome. 2018 Jun 8;6(1):101. doi: 10.1186/s40168-018-0479-3.

10.

The interplay between microbes and the immune response in inflammatory bowel disease.

Goethel A, Croitoru K, Philpott DJ.

J Physiol. 2018 Sep;596(17):3869-3882. doi: 10.1113/JP275396. Epub 2018 Jul 17.

PMID:
29806140
11.

Stricturing and Fistulizing Crohn's Disease Is Associated with Anti-tumor Necrosis Factor-Induced Psoriasis in Patients with Inflammatory Bowel Disease.

Weizman AV, Sharma R, Afzal NM, Xu W, Walsh S, Stempak JM, Nguyen GC, Croitoru K, Steinhart AH, Silverberg MS.

Dig Dis Sci. 2018 Sep;63(9):2430-2438. doi: 10.1007/s10620-018-5096-2. Epub 2018 May 8.

PMID:
29736839
12.

Assessment and management of diarrhea following VEGF receptor TKI treatment in patients with ovarian cancer.

Liu J, Nicum S, Reichardt P, Croitoru K, Illek B, Schmidinger M, Rogers C, Whalen C, Jayson GC.

Gynecol Oncol. 2018 Jul;150(1):173-179. doi: 10.1016/j.ygyno.2018.03.058. Epub 2018 Apr 5. Review.

PMID:
29627080
13.

FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects.

Turpin W, Bedrani L, Espin-Garcia O, Xu W, Silverberg MS, Smith MI, Guttman DS, Griffiths A, Moayyedi P, Panaccione R, Huynh H, Steinhart H, Aumais G, Shestopaloff K, Dieleman LA, Turner D, Paterson AD, Croitoru K.

Gut Microbes. 2018 Jul 4;9(4):357-368. doi: 10.1080/19490976.2018.1445956. Epub 2018 Apr 27.

14.

Development of the Harvey-Bradshaw Index-pro (HBI-PRO) Score to Assess Endoscopic Disease Activity in Crohn's Disease.

Zittan E, Kabakchiev B, Kelly OB, Milgrom R, Nguyen GC, Croitoru K, Steinhart AH, Silverberg MS.

J Crohns Colitis. 2017 May 1;11(5):543-548. doi: 10.1093/ecco-jcc/jjw200.

PMID:
28453763
15.

Public versus Private Drug Insurance and Outcomes of Patients Requiring Biologic Therapies for Inflammatory Bowel Disease.

Rumman A, Candia R, Sam JJ, Croitoru K, Silverberg MS, Steinhart AH, Nguyen GC.

Can J Gastroenterol Hepatol. 2017;2017:7365937. doi: 10.1155/2017/7365937. Epub 2017 Jan 23.

16.

Association of host genome with intestinal microbial composition in a large healthy cohort.

Turpin W, Espin-Garcia O, Xu W, Silverberg MS, Kevans D, Smith MI, Guttman DS, Griffiths A, Panaccione R, Otley A, Xu L, Shestopaloff K, Moreno-Hagelsieb G; GEM Project Research Consortium, Paterson AD, Croitoru K.

Nat Genet. 2016 Nov;48(11):1413-1417. doi: 10.1038/ng.3693. Epub 2016 Oct 3.

PMID:
27694960
17.

Preoperative Anti-tumor Necrosis Factor Therapy in Patients with Ulcerative Colitis Is Not Associated with an Increased Risk of Infectious and Noninfectious Complications After Ileal Pouch-anal Anastomosis.

Zittan E, Milgrom R, Ma GW, Wong-Chong N, OʼConnor B, McLeod RS, MacRae HM, Greenberg GR, Nguyen GC, Croitoru K, Steinhart AH, Cohen Z, Silverberg MS.

Inflamm Bowel Dis. 2016 Oct;22(10):2442-7. doi: 10.1097/MIB.0000000000000919.

PMID:
27607335
18.

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G, Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH.

Nat Commun. 2016 Aug 9;7:12342. doi: 10.1038/ncomms12342. Erratum in: Nat Commun. 2016 Sep 13;7:12869.

19.

The Cytosolic Microbial Receptor Nod2 Regulates Small Intestinal Crypt Damage and Epithelial Regeneration following T Cell-Induced Enteropathy.

Zanello G, Goethel A, Rouquier S, Prescott D, Robertson SJ, Maisonneuve C, Streutker C, Philpott DJ, Croitoru K.

J Immunol. 2016 Jul 1;197(1):345-55. doi: 10.4049/jimmunol.1600185. Epub 2016 May 20.

20.

Use of Complementary and Alternative Medicine for Inflammatory Bowel Disease Is Associated with Worse Adherence to Conventional Therapy: The COMPLIANT Study.

Nguyen GC, Croitoru K, Silverberg MS, Steinhart AH, Weizman AV.

Inflamm Bowel Dis. 2016 Jun;22(6):1412-7. doi: 10.1097/MIB.0000000000000773.

PMID:
27120570
21.

Low Fecal Calprotectin Correlates with Histological Remission and Mucosal Healing in Ulcerative Colitis and Colonic Crohn's Disease.

Zittan E, Kelly OB, Kirsch R, Milgrom R, Burns J, Nguyen GC, Croitoru K, Van Assche G, Silverberg MS, Steinhart AH.

Inflamm Bowel Dis. 2016 Mar;22(3):623-30. doi: 10.1097/MIB.0000000000000652.

PMID:
26829408
22.

Higher Adalimumab Drug Levels are Associated with Mucosal Healing in Patients with Crohn's Disease.

Zittan E, Kabakchiev B, Milgrom R, Nguyen GC, Croitoru K, Steinhart AH, Silverberg MS.

J Crohns Colitis. 2016 May;10(5):510-5. doi: 10.1093/ecco-jcc/jjw014. Epub 2016 Jan 18.

23.

IBD Genetic Risk Profile in Healthy First-Degree Relatives of Crohn's Disease Patients.

Kevans D, Silverberg MS, Borowski K, Griffiths A, Xu W, Onay V, Paterson AD, Knight J, Croitoru K; GEM Project.

J Crohns Colitis. 2016 Feb;10(2):209-15. doi: 10.1093/ecco-jcc/jjv197. Epub 2015 Oct 28.

24.

Predictors of Outcome in Ulcerative Colitis.

Waterman M, Knight J, Dinani A, Xu W, Stempak JM, Croitoru K, Nguyen GC, Cohen Z, McLeod RS, Greenberg GR, Steinhart AH, Silverberg MS.

Inflamm Bowel Dis. 2015 Sep;21(9):2097-105. doi: 10.1097/MIB.0000000000000466.

PMID:
26177304
25.

Extent of Early Clinical Response to Infliximab Predicts Long-term Treatment Success in Active Ulcerative Colitis.

Murthy SK, Greenberg GR, Croitoru K, Nguyen GC, Silverberg MS, Steinhart AH.

Inflamm Bowel Dis. 2015 Sep;21(9):2090-6. doi: 10.1097/MIB.0000000000000474.

PMID:
26099066
26.

Vaccination in inflammatory bowel disease patients: attitudes, knowledge, and uptake.

Malhi G, Rumman A, Thanabalan R, Croitoru K, Silverberg MS, Hillary Steinhart A, Nguyen GC.

J Crohns Colitis. 2015 Jun;9(6):439-44. doi: 10.1093/ecco-jcc/jjv064. Epub 2015 Apr 23.

PMID:
25908717
27.

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents.

Luck H, Tsai S, Chung J, Clemente-Casares X, Ghazarian M, Revelo XS, Lei H, Luk CT, Shi SY, Surendra A, Copeland JK, Ahn J, Prescott D, Rasmussen BA, Chng MH, Engleman EG, Girardin SE, Lam TK, Croitoru K, Dunn S, Philpott DJ, Guttman DS, Woo M, Winer S, Winer DA.

Cell Metab. 2015 Apr 7;21(4):527-42. doi: 10.1016/j.cmet.2015.03.001.

28.

Asthma, type 1 and type 2 diabetes mellitus, and inflammatory bowel disease amongst South Asian immigrants to Canada and their children: a population-based cohort study.

Benchimol EI, Manuel DG, To T, Mack DR, Nguyen GC, Gommerman JL, Croitoru K, Mojaverian N, Wang X, Quach P, Guttmann A.

PLoS One. 2015 Apr 7;10(4):e0123599. doi: 10.1371/journal.pone.0123599. eCollection 2015.

29.

Determinants of intestinal permeability in healthy first-degree relatives of individuals with Crohn's disease.

Kevans D, Turpin W, Madsen K, Meddings J, Shestopaloff K, Xu W, Moreno-Hagelsieb G, Griffiths A, Silverberg MS, Paterson A, Croitoru K; GEM Project.

Inflamm Bowel Dis. 2015 Apr;21(4):879-87. doi: 10.1097/MIB.0000000000000323. Erratum in: Inflamm Bowel Dis. 2015 Jul.21(7):1673.

PMID:
25734694
30.

Management of diarrhea induced by epidermal growth factor receptor tyrosine kinase inhibitors.

Hirsh V, Blais N, Burkes R, Verma S, Croitoru K.

Curr Oncol. 2014 Dec;21(6):329-36. doi: 10.3747/co.21.2241.

31.

Genetics and innate and adaptive immunity in IBD.

Zanello G, Kevans D, Goethel A, Silverberg M, Tyler A, Croitoru K.

Nestle Nutr Inst Workshop Ser. 2014;79:41-55. doi: 10.1159/000360676. Epub 2014 Sep 5. Review.

PMID:
25227294
32.

Microbiome analysis - from technical advances to biological relevance.

Smith MI, Turpin W, Tyler AD, Silverberg MS, Croitoru K.

F1000Prime Rep. 2014 Jul 8;6:51. doi: 10.12703/P6-51. eCollection 2014. Review.

33.

NOD proteins: regulators of inflammation in health and disease.

Philpott DJ, Sorbara MT, Robertson SJ, Croitoru K, Girardin SE.

Nat Rev Immunol. 2014 Jan;14(1):9-23. doi: 10.1038/nri3565. Epub 2013 Dec 13. Review. Erratum in: Nat Rev Immunol. 2014 Feb;14(2):131.

PMID:
24336102
34.

Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.

Zanello G, Goethel A, Forster K, Geddes K, Philpott DJ, Croitoru K.

PLoS One. 2013 Dec 6;8(12):e82623. doi: 10.1371/journal.pone.0082623. eCollection 2013.

35.

An oral CD3-specific antibody suppresses T-cell-induced colitis and alters cytokine responses to T-cell activation in mice.

Forster K, Goethel A, Chan CW, Zanello G, Streutker C, Croitoru K.

Gastroenterology. 2012 Nov;143(5):1298-1307. doi: 10.1053/j.gastro.2012.07.019. Epub 2012 Jul 20.

PMID:
22819863
36.

Preoperative biological therapy and short-term outcomes of abdominal surgery in patients with inflammatory bowel disease.

Waterman M, Xu W, Dinani A, Steinhart AH, Croitoru K, Nguyen GC, McLeod RS, Greenberg GR, Cohen Z, Silverberg MS.

Gut. 2013 Mar;62(3):387-94. doi: 10.1136/gutjnl-2011-301495. Epub 2012 May 22.

PMID:
22619367
37.

Prevalence and predictors of MRSA, ESBL, and VRE colonization in the ambulatory IBD population.

Leung W, Malhi G, Willey BM, McGeer AJ, Borgundvaag B, Thanabalan R, Gnanasuntharam P, Le B, Weizman AV, Croitoru K, Silverberg MS, Steinhart AH, Nguyen GC.

J Crohns Colitis. 2012 Aug;6(7):743-9. doi: 10.1016/j.crohns.2011.12.005. Epub 2012 Jan 9.

PMID:
22398097
38.

Bacterial biogeography of the human digestive tract.

Stearns JC, Lynch MD, Senadheera DB, Tenenbaum HC, Goldberg MB, Cvitkovitch DG, Croitoru K, Moreno-Hagelsieb G, Neufeld JD.

Sci Rep. 2011;1:170. doi: 10.1038/srep00170. Epub 2011 Nov 25.

39.

Characterisation of complementary and alternative medicine use and its impact on medication adherence in inflammatory bowel disease.

Weizman AV, Ahn E, Thanabalan R, Leung W, Croitoru K, Silverberg MS, Steinhart AH, Nguyen GC.

Aliment Pharmacol Ther. 2012 Feb;35(3):342-9. doi: 10.1111/j.1365-2036.2011.04956.x. Epub 2011 Dec 18.

40.

Research Topics in Gastrointestinal Disease: a report on the 10th meeting and an announcement of the 11th meeting.

Jones NL, Croitoru K, Vanner S, Soni R, Hope L.

Can J Gastroenterol. 2011 Aug;25(8):449-50. No abstract available.

41.

Canadian Association of Gastroenterology Clinical Practice Guidelines: The use of tumour necrosis factor-alpha antagonist therapy in Crohn's disease.

Sadowski DC, Bernstein CN, Bitton A, Croitoru K, Fedorak RN, Griffiths A; CAG Crohn's Consensus Group.

Can J Gastroenterol. 2009 Mar;23(3):185-202. Review.

42.

Regulatory T cells modulate staphylococcal enterotoxin B-induced effector T-cell activation and acceleration of colitis.

Heriazon A, Zhou P, Borojevic R, Foerster K, Streutker CJ, Ng T, Croitoru K.

Infect Immun. 2009 Feb;77(2):707-13. doi: 10.1128/IAI.00822-08. Epub 2008 Dec 8.

43.

The role of luminal factors in the recovery of gastric function and behavioral changes after chronic Helicobacter pylori infection.

Verdu EF, Bercik P, Huang XX, Lu J, Al-Mutawaly N, Sakai H, Tompkins TA, Croitoru K, Tsuchida E, Perdue M, Collins SM.

Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G664-70. doi: 10.1152/ajpgi.90316.2008. Epub 2008 Jul 24.

44.

Review and clinical perspectives for the use of infliximab in ulcerative colitis.

Panaccione R, Fedorak RN, Aumais G, Bernard EJ, Bernstein CN, Bitton A, Croitoru K, Dieleman LA, Enns R, Feagan BG, Franchimont D, Greenberg GR, Griffiths AM, Marshall JK, Pare P, Patel S, Penner R, Render C, Seidman E, Steinhart AH.

Can J Gastroenterol. 2008 Mar;22(3):261-72. Review.

45.

Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2.

Wu L, Feng BS, He SH, Zheng PY, Croitoru K, Yang PC.

Immunol Cell Biol. 2007 Oct;85(7):538-45. Epub 2007 Jun 12.

PMID:
17563761
46.

Induction versus noninduction antiviral therapy for chronic hepatitis C virus in patients with congenital coagulation disorders: a Canadian multicentre trial.

Chatterjee A, Swain MG, Lee SS, Bain VG, Peltekian K, Croitoru K, Adams PC, Kaita K, Teitel J, Heathcote EJ.

Can J Gastroenterol. 2007 Feb;21(2):91-5.

47.

13C urea breath test for (Helicobacter pylori): determination of the optimal cut-off point in a Canadian community population.

Mauro M, Radovic V, Zhou P, Wolfe M, Kamath M, Bercik P, Croitoru K, Armstrong D.

Can J Gastroenterol. 2006 Dec;20(12):770-4.

48.

IL-10 protects mouse intestinal epithelial cells from Fas-induced apoptosis via modulating Fas expression and altering caspase-8 and FLIP expression.

Bharhani MS, Borojevic R, Basak S, Ho E, Zhou P, Croitoru K.

Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G820-9.

49.

Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.

Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stämpfli MR, Jordana M.

J Immunol. 2006 Feb 15;176(4):2568-80.

50.

T-cell-induced mucosal damage in the intestine.

Croitoru K, Zhou P.

Curr Opin Gastroenterol. 2004 Nov;20(6):581-6.

PMID:
15703686

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