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Items: 1 to 50 of 64

1.

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting.

Liu AY, Kanan AD, Radon TP, Shah S, Weeks ME, Foster JM, Sosabowski JK, Dumartin L, Crnogorac-Jurcevic T.

Oncotarget. 2019 Jul 2;10(42):4276-4289. doi: 10.18632/oncotarget.26945. eCollection 2019 Jul 2.

2.

Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors.

Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C, Solomou A, Herincs M, Caimari F, Grossman AB, Crnogorac-Jurcevic T, Haworth O, Gaston-Massuet C, Korbonits M.

Oncogene. 2019 Jul;38(27):5381-5395. doi: 10.1038/s41388-019-0779-5. Epub 2019 Mar 12.

3.

Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling.

Alrawashdeh W, Jones R, Dumartin L, Radon TP, Cutillas PR, Feakins RM, Dmitrovic B, Demir IE, Ceyhan GO, Crnogorac-Jurcevic T.

Mol Oncol. 2019 May;13(5):1075-1091. doi: 10.1002/1878-0261.12463. Epub 2019 Mar 5.

4.

Pancreatic cancer and autoimmune diseases: An association sustained by computational and epidemiological case-control approaches.

Gomez-Rubio P, Piñero J, Molina-Montes E, Gutiérrez-Sacristán A, Marquez M, Rava M, Michalski CW, Farré A, Molero X, Löhr M, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberá VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Balsells J, Costello E, Yu J, Iglesias M, Ilzarbe L, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Poves I, Lawlor RT, Ye W, Hidalgo M, Scarpa A, Sharp L, Carrato A, Real FX, Furlong LI, Malats N; PanGenEU Study Investigators.

Int J Cancer. 2019 Apr 1;144(7):1540-1549. doi: 10.1002/ijc.31866. Epub 2018 Oct 26.

PMID:
30229903
5.

Demographic, clinical, and pathological features of early onset pancreatic cancer patients.

Ntala C, Debernardi S, Feakins RM, Crnogorac-Jurcevic T.

BMC Gastroenterol. 2018 Sep 12;18(1):139. doi: 10.1186/s12876-018-0866-z.

6.

Risk of pancreatic cancer associated with family history of cancer and other medical conditions by accounting for smoking among relatives.

Molina-Montes E, Gomez-Rubio P, Márquez M, Rava M, Löhr M, Michalski CW, Molero X, Farré A, Perea J, Greenhalf W, Ilzarbe L, O'Rorke M, Tardón A, Gress T, Barberà VM, Crnogorac-Jurcevic T, Domínguez-Muñoz E, Muñoz-Bellvís L, Balsells J, Costello E, Huang J, Iglesias M, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Poves I, Scarpa A, Ye W, Hidalgo M, Sharp L, Carrato A, Real FX, Malats N; PanGenEU Study Investigators.

Int J Epidemiol. 2018 Apr 1;47(2):473-483. doi: 10.1093/ije/dyx269.

PMID:
29329392
7.

Noninvasive Diagnosis of Pancreatic Cancer Through Detection of Volatile Organic Compounds in Urine.

Arasaradnam RP, Wicaksono A, O'Brien H, Kocher HM, Covington JA, Crnogorac-Jurcevic T.

Gastroenterology. 2018 Feb;154(3):485-487.e1. doi: 10.1053/j.gastro.2017.09.054. Epub 2017 Nov 10. No abstract available.

PMID:
29129714
8.

The Pancreatic Expression Database: 2018 update.

Marzec J, Dayem Ullah AZ, Pirrò S, Gadaleta E, Crnogorac-Jurcevic T, Lemoine NR, Kocher HM, Chelala C.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1107-D1110. doi: 10.1093/nar/gkx955.

9.

Splice variants as novel targets in pancreatic ductal adenocarcinoma.

Wang J, Dumartin L, Mafficini A, Ulug P, Sangaralingam A, Alamiry NA, Radon TP, Salvia R, Lawlor RT, Lemoine NR, Scarpa A, Chelala C, Crnogorac-Jurcevic T.

Sci Rep. 2017 Jun 7;7(1):2980. doi: 10.1038/s41598-017-03354-z.

10.

A systems approach identifies time-dependent associations of multimorbidities with pancreatic cancer risk.

Gomez-Rubio P, Rosato V, Márquez M, Bosetti C, Molina-Montes E, Rava M, Piñero J, Michalski CW, Farré A, Molero X, Löhr M, Ilzarbe L, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberá VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Gutiérrez-Sacristán A, Balsells J, Costello E, Guillén-Ponce C, Huang J, Iglesias M, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Peláez P, Poves I, Lawlor RT, Carrato A, Hidalgo M, Scarpa A, Sharp L, Furlong LI, Real FX, La Vecchia C, Malats N; PanGenEU Study Investigators.

Ann Oncol. 2017 Jul 1;28(7):1618-1624. doi: 10.1093/annonc/mdx167.

PMID:
28383714
11.

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.

Dumartin L, Alrawashdeh W, Trabulo SM, Radon TP, Steiger K, Feakins RM, di Magliano MP, Heeschen C, Esposito I, Lemoine NR, Crnogorac-Jurcevic T.

Oncogene. 2017 Jun 1;36(22):3094-3103. doi: 10.1038/onc.2016.459. Epub 2016 Dec 12.

12.

The life and works of S100P - from conception to cancer.

Prica F, Radon T, Cheng Y, Crnogorac-Jurcevic T.

Am J Cancer Res. 2016 Jan 15;6(2):562-76. eCollection 2016. Review.

13.

Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma.

Debernardi S, Massat NJ, Radon TP, Sangaralingam A, Banissi A, Ennis DP, Dowe T, Chelala C, Pereira SP, Kocher HM, Young BD, Bond-Smith G, Hutchins R, Crnogorac-Jurcevic T.

Am J Cancer Res. 2015 Oct 15;5(11):3455-66. eCollection 2015.

14.

Application of Proteomics in Cancer Biomarker Discovery: GeLC-MS/MS.

Cutillas PR, Crnogorac-Jurcevic T.

Methods Mol Biol. 2016;1381:201-9. doi: 10.1007/978-1-4939-3204-7_11.

PMID:
26667462
15.

Reduced risk of pancreatic cancer associated with asthma and nasal allergies.

Gomez-Rubio P, Zock JP, Rava M, Marquez M, Sharp L, Hidalgo M, Carrato A, Ilzarbe L, Michalski C, Molero X, Farré A, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberà V, Crnogorac-Jurcevic T, Domínguez-Muñoz E, Muñoz-Bellvís L, Alvarez-Urturi C, Balcells J, Barneo L, Costello E, Guillén-Ponce C, Kleeff J, Kong B, Lawlor R, Löhr M, Mora J, Murray L, O'Driscoll D, Peláez P, Poves I, Scarpa A, Real FX, Malats N; PanGenEU Study Investigators.

Gut. 2017 Feb;66(2):314-322. doi: 10.1136/gutjnl-2015-310442. Epub 2015 Dec 1. Review.

PMID:
26628509
16.

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma.

Radon TP, Massat NJ, Jones R, Alrawashdeh W, Dumartin L, Ennis D, Duffy SW, Kocher HM, Pereira SP, Guarner posthumous L, Murta-Nascimento C, Real FX, Malats N, Neoptolemos J, Costello E, Greenhalf W, Lemoine NR, Crnogorac-Jurcevic T.

Clin Cancer Res. 2015 Aug 1;21(15):3512-21. doi: 10.1158/1078-0432.CCR-14-2467.

17.

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma.

Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T, Marshall JF, Kocher HM, Crnogorac-Jurcevic T, Scarpa A, Lemoine NR, Chelala C.

Genome Med. 2014 Dec 3;6(12):105. doi: 10.1186/s13073-014-0105-3. eCollection 2014.

18.

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.

Wong PP, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford MR, Scudamore CL, Cereser B, Crnogorac-Jurcevic T, McDonald S, Elia G, Hagemann T, Kocher HM, Hodivala-Dilke KM.

Cancer Cell. 2015 Jan 12;27(1):123-37. doi: 10.1016/j.ccell.2014.10.015.

19.

The pancreatic expression database: recent extensions and updates.

Dayem Ullah AZ, Cutts RJ, Ghetia M, Gadaleta E, Hahn SA, Crnogorac-Jurcevic T, Lemoine NR, Chelala C.

Nucleic Acids Res. 2014 Jan;42(Database issue):D944-9. doi: 10.1093/nar/gkt959. Epub 2013 Oct 25.

20.

Molecular analysis of precursor lesions in familial pancreatic cancer.

Crnogorac-Jurcevic T, Chelala C, Barry S, Harada T, Bhakta V, Lattimore S, Jurcevic S, Bronner M, Lemoine NR, Brentnall TA.

PLoS One. 2013;8(1):e54830. doi: 10.1371/journal.pone.0054830. Epub 2013 Jan 23.

21.

Antibody combination therapy targeting CD25, CD70 and CD8 reduces islet inflammation and improves glycaemia in diabetic mice.

Alkhamis T, Barbic J, Crnogorac-Jurcevic T, Greenlaw RE, Peakman M, Jurcevic S.

Clin Exp Immunol. 2012 Nov;170(2):139-48. doi: 10.1111/j.1365-2249.2012.04651.x.

22.

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells.

Barry S, Chelala C, Lines K, Sunamura M, Wang A, Marelli-Berg FM, Brennan C, Lemoine NR, Crnogorac-Jurcevic T.

Clin Exp Metastasis. 2013 Mar;30(3):251-64. doi: 10.1007/s10585-012-9532-y. Epub 2012 Sep 25.

PMID:
23007696
23.

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

Lines KE, Chelala C, Dmitrovic B, Wijesuriya N, Kocher HM, Marshall JF, Crnogorac-Jurcevic T.

Am J Pathol. 2012 Apr;180(4):1485-94. doi: 10.1016/j.ajpath.2011.12.031. Epub 2012 Feb 11.

PMID:
22330678
24.

Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastases.

Naidoo K, Jones R, Dmitrovic B, Wijesuriya N, Kocher H, Hart IR, Crnogorac-Jurcevic T.

J Pathol. 2012 Apr;226(5):756-63. doi: 10.1002/path.3959. Epub 2012 Jan 17. Erratum in: J Pathol. 2012 Aug;227(4):e8.

PMID:
22081483
25.

AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D.

Dumartin L, Whiteman HJ, Weeks ME, Hariharan D, Dmitrovic B, Iacobuzio-Donahue CA, Brentnall TA, Bronner MP, Feakins RM, Timms JF, Brennan C, Lemoine NR, Crnogorac-Jurcevic T.

Cancer Res. 2011 Nov 15;71(22):7091-102. doi: 10.1158/0008-5472.CAN-11-1367. Epub 2011 Sep 26.

26.

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

Gadaleta E, Cutts RJ, Kelly GP, Crnogorac-Jurcevic T, Kocher HM, Lemoine NR, Chelala C.

Nucleic Acids Res. 2011 Oct;39(18):7900-7. doi: 10.1093/nar/gkr533. Epub 2011 Jun 30.

27.

The Pancreatic Expression database: 2011 update.

Cutts RJ, Gadaleta E, Hahn SA, Crnogorac-Jurcevic T, Lemoine NR, Chelala C.

Nucleic Acids Res. 2011 Jan;39(Database issue):D1023-8. doi: 10.1093/nar/gkq937. Epub 2010 Oct 18.

28.

PRSS3 promotes tumour growth and metastasis of human pancreatic cancer.

Jiang G, Cao F, Ren G, Gao D, Bhakta V, Zhang Y, Cao H, Dong Z, Zang W, Zhang S, Wong HH, Hiley C, Crnogorac-Jurcevic T, Lemoine NR, Wang Y.

Gut. 2010 Nov;59(11):1535-44. doi: 10.1136/gut.2009.200105.

PMID:
20947888
29.

Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth.

Tolhurst RS, Thomas RS, Kyle FJ, Patel H, Periyasamy M, Photiou A, Thiruchelvam PT, Lai CF, Al-Sabbagh M, Fisher RA, Barry S, Crnogorac-Jurcevic T, Martin LA, Dowsett M, Charles Coombes R, Kamalati T, Ali S, Buluwela L.

Breast Cancer Res Treat. 2011 Jul;128(2):357-68. doi: 10.1007/s10549-010-1122-6. Epub 2010 Aug 22.

PMID:
20730598
30.

Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-related antibodies.

Schröder C, Jacob A, Tonack S, Radon TP, Sill M, Zucknick M, Rüffer S, Costello E, Neoptolemos JP, Crnogorac-Jurcevic T, Bauer A, Fellenberg K, Hoheisel JD.

Mol Cell Proteomics. 2010 Jun;9(6):1271-80. doi: 10.1074/mcp.M900419-MCP200. Epub 2010 Feb 16.

31.

Application of proteomics in cancer gene profiling: two-dimensional difference in gel electrophoresis (2D-DIGE).

Hariharan D, Weeks ME, Crnogorac-Jurcevic T.

Methods Mol Biol. 2010;576:197-211. doi: 10.1007/978-1-59745-545-9_11.

PMID:
19882264
32.

A web-based platform for mining pancreatic expression datasets.

Chelala C, Lemoine NR, Hahn SA, Crnogorac-Jurcevic T.

Pancreatology. 2009;9(4):340-3. doi: 10.1159/000212082. Epub 2009 May 18.

PMID:
19451743
33.

Genome-wide analysis of pancreatic cancer using microarray-based techniques.

Harada T, Chelala C, Crnogorac-Jurcevic T, Lemoine NR.

Pancreatology. 2009;9(1-2):13-24. doi: 10.1159/000178871. Epub 2008 Dec 12. Review.

PMID:
19077451
34.

Analysis of the urine proteome in patients with pancreatic ductal adenocarcinoma.

Weeks ME, Hariharan D, Petronijevic L, Radon TP, Whiteman HJ, Kocher HM, Timms JF, Lemoine NR, Crnogorac-Jurcevic T.

Proteomics Clin Appl. 2008 Jul;2(7-8):1047-57. doi: 10.1002/prca.200780164. Epub 2008 Jul 10.

PMID:
21136905
35.

Pancreatic Expression database: a generic model for the organization, integration and mining of complex cancer datasets.

Chelala C, Hahn SA, Whiteman HJ, Barry S, Hariharan D, Radon TP, Lemoine NR, Crnogorac-Jurcevic T.

BMC Genomics. 2007 Nov 28;8:439.

36.

The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D.

Whiteman HJ, Weeks ME, Dowen SE, Barry S, Timms JF, Lemoine NR, Crnogorac-Jurcevic T.

Cancer Res. 2007 Sep 15;67(18):8633-42.

37.

The expression of S100A8 in pancreatic cancer-associated monocytes is associated with the Smad4 status of pancreatic cancer cells.

Sheikh AA, Vimalachandran D, Thompson CC, Jenkins RE, Nedjadi T, Shekouh A, Campbell F, Dodson A, Prime W, Crnogorac-Jurcevic T, Lemoine NR, Costello E.

Proteomics. 2007 Jun;7(11):1929-40.

PMID:
17469085
38.

Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism.

Pogue-Geile KL, Chen R, Bronner MP, Crnogorac-Jurcevic T, Moyes KW, Dowen S, Otey CA, Crispin DA, George RD, Whitcomb DC, Brentnall TA.

PLoS Med. 2006 Dec;3(12):e516.

39.

Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway.

Baril P, Gangeswaran R, Mahon PC, Caulee K, Kocher HM, Harada T, Zhu M, Kalthoff H, Crnogorac-Jurcevic T, Lemoine NR.

Oncogene. 2007 Mar 29;26(14):2082-94. Epub 2006 Oct 9.

PMID:
17043657
40.

Sperm-associated antigen 1 is expressed early in pancreatic tumorigenesis and promotes motility of cancer cells.

Neesse A, Gangeswaran R, Luettges J, Feakins R, Weeks ME, Lemoine NR, Crnogorac-Jurcevic T.

Oncogene. 2007 Mar 8;26(11):1533-45. Epub 2006 Sep 18.

PMID:
16983343
41.

Pancreatic cancer cells overexpress gelsolin family-capping proteins, which contribute to their cell motility.

Thompson CC, Ashcroft FJ, Patel S, Saraga G, Vimalachandran D, Prime W, Campbell F, Dodson A, Jenkins RE, Lemoine NR, Crnogorac-Jurcevic T, Yin HL, Costello E.

Gut. 2007 Jan;56(1):95-106. Epub 2006 Jul 17.

42.

Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets.

Capurso G, Lattimore S, Crnogorac-Jurcevic T, Panzuto F, Milione M, Bhakta V, Campanini N, Swift SM, Bordi C, Delle Fave G, Lemoine NR.

Endocr Relat Cancer. 2006 Jun;13(2):541-58.

PMID:
16728581
43.

Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma.

Crnogorac-Jurcevic T, Gangeswaran R, Bhakta V, Capurso G, Lattimore S, Akada M, Sunamura M, Prime W, Campbell F, Brentnall TA, Costello E, Neoptolemos J, Lemoine NR.

Gastroenterology. 2005 Nov;129(5):1454-63.

PMID:
16285947
44.

Peanut-like 1 (septin 5) gene expression in normal and neoplastic human endocrine pancreas.

Capurso G, Crnogorac-Jurcevic T, Milione M, Panzuto F, Campanini N, Dowen SE, Di Florio A, Sette C, Bordi C, Lemoine NR, Delle Fave G.

Neuroendocrinology. 2005;81(5):311-21. Epub 2005 Sep 21.

PMID:
16179808
45.

Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer.

Akada M, Crnogorac-Jurcevic T, Lattimore S, Mahon P, Lopes R, Sunamura M, Matsuno S, Lemoine NR.

Clin Cancer Res. 2005 Apr 15;11(8):3094-101.

46.

High nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patients.

Vimalachandran D, Greenhalf W, Thompson C, Lüttges J, Prime W, Campbell F, Dodson A, Watson R, Crnogorac-Jurcevic T, Lemoine N, Neoptolemos J, Costello E.

Cancer Res. 2005 Apr 15;65(8):3218-25.

47.

Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.

Missiaglia E, Donadelli M, Palmieri M, Crnogorac-Jurcevic T, Scarpa A, Lemoine NR.

Oncogene. 2005 Jan 6;24(1):199-211.

PMID:
15637593
48.

Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer.

Dowen SE, Crnogorac-Jurcevic T, Gangeswaran R, Hansen M, Eloranta JJ, Bhakta V, Brentnall TA, Lüttges J, Klöppel G, Lemoine NR.

Am J Pathol. 2005 Jan;166(1):81-92.

49.

Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis.

Missiaglia E, Blaveri E, Terris B, Wang YH, Costello E, Neoptolemos JP, Crnogorac-Jurcevic T, Lemoine NR.

Int J Cancer. 2004 Oct 20;112(1):100-12.

50.

Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma.

Shekouh AR, Thompson CC, Prime W, Campbell F, Hamlett J, Herrington CS, Lemoine NR, Crnogorac-Jurcevic T, Buechler MW, Friess H, Neoptolemos JP, Pennington SR, Costello E.

Proteomics. 2003 Oct;3(10):1988-2001.

PMID:
14625861

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