Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 248


Physical Therapy Informed by Acceptance and Commitment Therapy (PACT) Versus Usual Care Physical Therapy for Adults With Chronic Low Back Pain: A Randomized Controlled Trial.

Godfrey E, Wileman V, Galea Holmes M, McCracken LM, Norton S, Moss-Morris R, Noonan S, Barcellona M, Critchley D.

J Pain. 2019 Jun 5. pii: S1526-5900(19)30065-3. doi: 10.1016/j.jpain.2019.05.012. [Epub ahead of print]


Association between sympathoexcitatory changes and symptomatic improvement following cervical mobilisations in participants with neck pain. A double blind placebo controlled trial.

Lascurain-Aguirrebeña I, Newham DJ, Galindez-Ibarbengoetxea X, Casado-Zumeta X, Lertxundi A, Critchley DJ.

Musculoskelet Sci Pract. 2019 Jul;42:90-97. doi: 10.1016/j.msksp.2019.05.001. Epub 2019 May 2.


Immediate effects of cervical mobilisations on global perceived effect, movement associated pain and neck kinematics in patients with non-specific neck pain. A double blind placebo randomised controlled trial.

Lascurain-Aguirrebeña I, Newham DJ, Casado-Zumeta X, Lertxundi A, Critchley DJ.

Musculoskelet Sci Pract. 2018 Dec;38:83-90. doi: 10.1016/j.msksp.2018.10.003. Epub 2018 Oct 13.


Reliability of a Method to Measure Neck Surface Electromyography, Kinematics, and Pain Occurrence in Participants With Neck Pain.

Lascurain-Aguirrebeña I, Newham DJ, Irazusta J, Seco J, Critchley DJ.

J Manipulative Physiol Ther. 2018 Jun;41(5):413-424. doi: 10.1016/j.jmpt.2017.10.013.


Differences in neck surface electromyography, kinematics and pain occurrence during physiological neck movements between neck pain and asymptomatic participants. A cross-sectional study.

Lascurain-Aguirrebeña I, Newham DJ, Galarraga-Gallastegui B, Critchley DJ.

Clin Biomech (Bristol, Avon). 2018 Aug;57:1-9. doi: 10.1016/j.clinbiomech.2018.05.010. Epub 2018 May 22.


Comparison of standing postural control and gait parameters in people with and without chronic low back pain: a cross-sectional case-control study.

MacRae CS, Critchley D, Lewis JS, Shortland A.

BMJ Open Sport Exerc Med. 2018 Jan 23;4(1):e000286. doi: 10.1136/bmjsem-2017-000286. eCollection 2018.


Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.

Mathew S, Palamuttam RJ, Mernaugh G, Ramalingam H, Lu Z, Zhang MZ, Ishibe S, Critchley DR, Fässler R, Pozzi A, Sanders CR, Carroll TJ, Zent R.

Development. 2017 Nov 15;144(22):4148-4158. doi: 10.1242/dev.149914. Epub 2017 Oct 9.


Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.

Manso AM, Okada H, Sakamoto FM, Moreno E, Monkley SJ, Li R, Critchley DR, Ross RS.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6250-E6259. doi: 10.1073/pnas.1701416114. Epub 2017 Jul 11.


Do rocker-sole shoes influence postural stability in chronic low back pain? A randomised trial.

MacRae CS, Critchley D, Morrissey M, Shortland A, Lewis JS.

BMJ Open Sport Exerc Med. 2016 Oct 19;2(1):e000170. eCollection 2016.


Do isometric pull-down exercises increase the acromio-humeral distance?

Sealey P, Critchley D.

Physiotherapy. 2017 Jun;103(2):208-213. doi: 10.1016/ Epub 2016 May 6.


Physiotherapy informed by Acceptance and Commitment Therapy (PACT): protocol for a randomised controlled trial of PACT versus usual physiotherapy care for adults with chronic low back pain.

Godfrey E, Galea Holmes M, Wileman V, McCracken L, Norton S, Moss-Morris R, Pallet J, Sanders D, Barcellona M, Critchley D.

BMJ Open. 2016 Jun 7;6(6):e011548. doi: 10.1136/bmjopen-2016-011548.


LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex.

Zacharchenko T, Qian X, Goult BT, Jethwa D, Almeida TB, Ballestrem C, Critchley DR, Lowy DR, Barsukov IL.

Structure. 2016 Jul 6;24(7):1130-41. doi: 10.1016/j.str.2016.04.016. Epub 2016 Jun 2.


Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison.

Dubbelman AC, Nijenhuis CM, Jansen RS, Rosing H, Mizuo H, Kawaguchi S, Critchley D, Shumaker R, Schellens JH, Beijnen JH.

Invest New Drugs. 2016 Jun;34(3):300-18. doi: 10.1007/s10637-016-0342-y. Epub 2016 Mar 28.


Translation, cross-cultural adaptation and psychometric properties of the Back Beliefs Questionnaire in Modern Standard Arabic.

Maki D, Rajab E, Watson PJ, Critchley DJ.

Disabil Rehabil. 2017 Feb;39(3):272-280. doi: 10.3109/09638288.2016.1140832. Epub 2016 Mar 10.


Safety and pharmacokinetic profile of rufinamide in pediatric patients aged less than 4 years with Lennox-Gastaut syndrome: An interim analysis from a multicenter, randomized, active-controlled, open-label study.

Arzimanoglou A, Ferreira JA, Satlin A, Mendes S, Williams B, Critchley D, Schuck E, Hussein Z, Kumar D, Dhadda S, Bibbiani F.

Eur J Paediatr Neurol. 2016 May;20(3):393-402. doi: 10.1016/j.ejpn.2015.12.015. Epub 2016 Jan 11.


Mechanism of Action of Spinal Mobilizations: A Systematic Review.

Lascurain-Aguirrebeña I, Newham D, Critchley DJ.

Spine (Phila Pa 1976). 2016 Jan;41(2):159-72. doi: 10.1097/BRS.0000000000001151. Review.


Vinculin controls talin engagement with the actomyosin machinery.

Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C.

Nat Commun. 2015 Dec 4;6:10038. doi: 10.1038/ncomms10038.


Talin determines the nanoscale architecture of focal adhesions.

Liu J, Wang Y, Goh WI, Goh H, Baird MA, Ruehland S, Teo S, Bate N, Critchley DR, Davidson MW, Kanchanawong P.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4864-73. doi: 10.1073/pnas.1512025112. Epub 2015 Aug 17.


Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration.

Rainero E, Howe JD, Caswell PT, Jamieson NB, Anderson K, Critchley DR, Machesky L, Norman JC.

Cell Rep. 2015 Jan 20;10(3):398-413. doi: 10.1016/j.celrep.2014.12.037. Epub 2015 Jan 15.


Cross-cultural translation, adaptation, and psychometric testing of the Roland-Morris disability questionnaire into modern standard Arabic.

Maki D, Rajab E, Watson PJ, Critchley DJ.

Spine (Phila Pa 1976). 2014 Dec 1;39(25):E1537-44. doi: 10.1097/BRS.0000000000000632.


In response.

MacRae CS, Lewis JS, Critchley DJ.

Spine (Phila Pa 1976). 2014 Feb 15;39(4):346. doi: 10.1097/BRS.0000000000000152. No abstract available.


Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.

Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S.

J Clin Invest. 2014 Mar;124(3):1098-113. doi: 10.1172/JCI69778. Epub 2014 Feb 17. Erratum in: J Clin Invest. 2015 Feb;125(2):882.


Effectiveness of rocker sole shoes in the management of chronic low back pain: a randomized clinical trial.

MacRae CS, Lewis JS, Shortland AP, Morrissey MC, Critchley D.

Spine (Phila Pa 1976). 2013 Oct 15;38(22):1905-12. doi: 10.1097/BRS.0b013e3182a69956.


Talins and kindlins: partners in integrin-mediated adhesion.

Calderwood DA, Campbell ID, Critchley DR.

Nat Rev Mol Cell Biol. 2013 Aug;14(8):503-17. doi: 10.1038/nrm3624. Epub 2013 Jul 17. Review.


Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.

Goult BT, Xu XP, Gingras AR, Swift M, Patel B, Bate N, Kopp PM, Barsukov IL, Critchley DR, Volkmann N, Hanein D.

J Struct Biol. 2013 Oct;184(1):21-32. doi: 10.1016/j.jsb.2013.05.014. Epub 2013 May 30.


RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.

Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GC, Ballestrem C, Critchley DR, Barsukov IL.

J Biol Chem. 2013 Mar 22;288(12):8238-49. doi: 10.1074/jbc.M112.438119. Epub 2013 Feb 6.


Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.

Manso AM, Li R, Monkley SJ, Cruz NM, Ong S, Lao DH, Koshman YE, Gu Y, Peterson KL, Chen J, Abel ED, Samarel AM, Critchley DR, Ross RS.

J Biol Chem. 2013 Feb 8;288(6):4252-64. doi: 10.1074/jbc.M112.427484. Epub 2012 Dec 24.


Talin1 and Rap1 are critical for osteoclast function.

Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley SJ, Critchley DR, Petrich BG, Morozov A, Ginsberg MH, Teitelbaum SL.

Mol Cell Biol. 2013 Feb;33(4):830-44. doi: 10.1128/MCB.00790-12. Epub 2012 Dec 10.


Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile.

Debrand E, Conti FJ, Bate N, Spence L, Mazzeo D, Pritchard CA, Monkley SJ, Critchley DR.

Biochem Biophys Res Commun. 2012 Sep 21;426(2):190-5. doi: 10.1016/j.bbrc.2012.08.061. Epub 2012 Aug 17.


Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.

Bate N, Gingras AR, Bachir A, Horwitz R, Ye F, Patel B, Goult BT, Critchley DR.

PLoS One. 2012;7(4):e34461. doi: 10.1371/journal.pone.0034461. Epub 2012 Apr 4.


Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.

Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K.

Blood. 2012 May 3;119(18):4275-82. doi: 10.1182/blood-2011-08-373118. Epub 2012 Mar 19.


Subcellular localization of talin is regulated by inter-domain interactions.

Banno A, Goult BT, Lee H, Bate N, Critchley DR, Ginsberg MH.

J Biol Chem. 2012 Apr 20;287(17):13799-812. doi: 10.1074/jbc.M112.341214. Epub 2012 Feb 18.


New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.

Praekelt U, Kopp PM, Rehm K, Linder S, Bate N, Patel B, Debrand E, Manso AM, Ross RS, Conti F, Zhang MZ, Harris RC, Zent R, Critchley DR, Monkley SJ.

Eur J Cell Biol. 2012 Mar;91(3):180-91. doi: 10.1016/j.ejcb.2011.12.003. Epub 2012 Feb 3.


A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.

Bouaouina M, Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, Critchley DR, Calderwood DA.

J Biol Chem. 2012 Mar 2;287(10):6979-90. doi: 10.1074/jbc.M111.330845. Epub 2012 Jan 10.


Contact-dependent T cell activation and T cell stopping require talin1.

Wernimont SA, Wiemer AJ, Bennin DA, Monkley SJ, Ludwig T, Critchley DR, Huttenlocher A.

J Immunol. 2011 Dec 15;187(12):6256-67. doi: 10.4049/jimmunol.1102028. Epub 2011 Nov 9.


Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake.

Truttmann MC, Misselwitz B, Huser S, Hardt WD, Critchley DR, Dehio C.

J Cell Sci. 2011 Nov 1;124(Pt 21):3591-602. doi: 10.1242/jcs.084459. Epub 2011 Nov 1.


Investigation of the metabolism of rufinamide and its interaction with valproate.

Williams ET, Carlson JE, Lai WG, Wong YN, Yoshimura T, Critchley DJ, Narurkar M.

Drug Metab Lett. 2011 Dec;5(4):280-9.


For sick-listed people with chronic low back pain, an integrated care programme costs society less and returns participants to work faster than usual management.

Critchley DJ.

Evid Based Med. 2011 Aug;16(4):105-6. doi: 10.1136/ebm1206. Epub 2011 Jun 20. No abstract available.


Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.

Liu J, He X, Qi Y, Tian X, Monkley SJ, Critchley DR, Corbett SA, Lowry SF, Graham AM, Li S.

Mol Cell Biol. 2011 Aug;31(16):3366-77. doi: 10.1128/MCB.01403-10. Epub 2011 Jun 13.


Tetraspanin CD9 in cell migration.

Powner D, Kopp PM, Monkley SJ, Critchley DR, Berditchevski F.

Biochem Soc Trans. 2011 Apr;39(2):563-7. doi: 10.1042/BST0390563. Review.


Bioavailability of three rufinamide oral suspensions compared with the marketed 400-mg tablet formulation: results from a randomized-sequence, open-label, four-period, four-sequence crossover study in healthy subjects.

Critchley DJ, Aluri J, Boyd P, Whayman M, Narurkar M, Delargy H, Bibbiani F.

Clin Ther. 2011 Jan;33(1):146-57. doi: 10.1016/j.clinthera.2011.01.016.


Structural diversity in integrin/talin interactions.

Anthis NJ, Wegener KL, Critchley DR, Campbell ID.

Structure. 2010 Dec 8;18(12):1654-66. doi: 10.1016/j.str.2010.09.018.


Endothelial cell talin1 is essential for embryonic angiogenesis.

Monkley SJ, Kostourou V, Spence L, Petrich B, Coleman S, Ginsberg MH, Pritchard CA, Critchley DR.

Dev Biol. 2011 Jan 15;349(2):494-502. doi: 10.1016/j.ydbio.2010.11.010. Epub 2010 Nov 26.


Effect of pilates mat exercises and conventional exercise programmes on transversus abdominis and obliquus internus abdominis activity: pilot randomised trial.

Critchley DJ, Pierson Z, Battersby G.

Man Ther. 2011 Apr;16(2):183-9. doi: 10.1016/j.math.2010.10.007. Epub 2010 Nov 12.


Talin-dependent integrin activation is required for fibrin clot retraction by platelets.

Haling JR, Monkley SJ, Critchley DR, Petrich BG.

Blood. 2011 Feb 3;117(5):1719-22. doi: 10.1182/blood-2010-09-305433. Epub 2010 Oct 22.


The Structure of the talin head reveals a novel extended conformation of the FERM domain.

Elliott PR, Goult BT, Kopp PM, Bate N, Grossmann JG, Roberts GC, Critchley DR, Barsukov IL.

Structure. 2010 Oct 13;18(10):1289-99. doi: 10.1016/j.str.2010.07.011.


Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen.

Manevich-Mendelson E, Grabovsky V, Feigelson SW, Cinamon G, Gore Y, Goverse G, Monkley SJ, Margalit R, Melamed D, Mebius RE, Critchley DR, Shachar I, Alon R.

Blood. 2010 Dec 23;116(26):5907-18. doi: 10.1182/blood-2010-06-293506. Epub 2010 Oct 5.


Rap1 controls activation of the α(M)β(2) integrin in a talin-dependent manner.

Lim J, Dupuy AG, Critchley DR, Caron E.

J Cell Biochem. 2010 Nov 1;111(4):999-1009. doi: 10.1002/jcb.22788.


Central region of talin has a unique fold that binds vinculin and actin.

Gingras AR, Bate N, Goult BT, Patel B, Kopp PM, Emsley J, Barsukov IL, Roberts GC, Critchley DR.

J Biol Chem. 2010 Sep 17;285(38):29577-87. doi: 10.1074/jbc.M109.095455. Epub 2010 Jul 7.


Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.

Kopp PM, Bate N, Hansen TM, Brindle NP, Praekelt U, Debrand E, Coleman S, Mazzeo D, Goult BT, Gingras AR, Pritchard CA, Critchley DR, Monkley SJ.

Eur J Cell Biol. 2010 Sep;89(9):661-73. doi: 10.1016/j.ejcb.2010.05.003.

Supplemental Content

Loading ...
Support Center