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Items: 1 to 50 of 52

1.

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates.

Milani M, Annoni A, Moalli F, Liu T, Cesana D, Calabria A, Bartolaccini S, Biffi M, Russo F, Visigalli I, Raimondi A, Patarroyo-White S, Drager D, Cristofori P, Ayuso E, Montini E, Peters R, Iannacone M, Cantore A, Naldini L.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7325. doi: 10.1126/scitranslmed.aav7325.

PMID:
31118293
2.

Ex Vivo Gene Therapy: Graft-versus-host Disease (GVHD) in NSG™ (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ) Mice Transplanted with CD34+ Human Hematopoietic Stem Cells.

Chandra S, Cristofori P, Fonck C, O'Neill CA.

Toxicol Pathol. 2019 Jul;47(5):656-660. doi: 10.1177/0192623319844484. Epub 2019 May 7.

PMID:
31064282
3.

Multiple Integrated Non-clinical Studies Predict the Safety of Lentivirus-Mediated Gene Therapy for β-Thalassemia.

Lidonnici MR, Paleari Y, Tiboni F, Mandelli G, Rossi C, Vezzoli M, Aprile A, Lederer CW, Ambrosi A, Chanut F, Sanvito F, Calabria A, Poletti V, Mavilio F, Montini E, Naldini L, Cristofori P, Ferrari G.

Mol Ther Methods Clin Dev. 2018 Sep 13;11:9-28. doi: 10.1016/j.omtm.2018.09.001. eCollection 2018 Dec 14.

4.

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells.

Norelli M, Camisa B, Barbiera G, Falcone L, Purevdorj A, Genua M, Sanvito F, Ponzoni M, Doglioni C, Cristofori P, Traversari C, Bordignon C, Ciceri F, Ostuni R, Bonini C, Casucci M, Bondanza A.

Nat Med. 2018 Jun;24(6):739-748. doi: 10.1038/s41591-018-0036-4. Epub 2018 May 28.

PMID:
29808007
5.

A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 2 of 2).

Hailey JR, Maleeff BE, Thomas HC, Pearse G, Klapwijk JC, Cristofori PG, Berridge B, Kimbrough CL, Parker GA, Morton D, Elmore S, Hardisty JF, Dybdal NO, Rehagen DA, Fikes JD, Lamb M, Biddle K, Buetow BS, Carreira V, Nyska A, Tripathi NK, Workman HC, Bienvenu JG, Brees I, Turk JR, Adler RR.

Toxicol Pathol. 2017 Dec;45(8):1055-1066. doi: 10.1177/0192623317743948.

PMID:
29233079
6.

A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2).

Hailey JR, Maleeff BE, Thomas HC, Pearse G, Klapwijk JC, Cristofori PG, Berridge B, Kimbrough CL, Parker GA, Morton D, Elmore S, Hardisty JF, Dybdal NO, Rehagen DA, Fikes JD, Lamb M, Biddle K, Buetow BS, Carreira V, Nyska A, Tripathi NK, Workman HC, Bienvenu JG, Brees I, Turk JR, Adler RR.

Toxicol Pathol. 2017 Dec;45(8):1043-1054. doi: 10.1177/0192623317743938. Epub 2017 Nov 26.

PMID:
29173114
7.

Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice.

Carriglio N, Klapwijk J, Hernandez RJ, Vezzoli M, Chanut F, Lowe R, Draghici E, Nord M, Albertini P, Cristofori P, Richards J, Staton H, Appleby J, Aiuti A, Sauer AV.

Hum Gene Ther Clin Dev. 2017 Mar;28(1):17-27. doi: 10.1089/humc.2016.191. Erratum in: Hum Gene Ther Clin Dev. 2017 Jun;28(2):116.

PMID:
28319446
8.

Preclinical Testing of the Safety and Tolerability of Lentiviral Vector-Mediated Above-Normal Alpha-L-Iduronidase Expression in Murine and Human Hematopoietic Cells Using Toxicology and Biodistribution Good Laboratory Practice Studies.

Visigalli I, Delai S, Ferro F, Cecere F, Vezzoli M, Sanvito F, Chanut F, Benedicenti F, Spinozzi G, Wynn R, Calabria A, Naldini L, Montini E, Cristofori P, Biffi A.

Hum Gene Ther. 2016 Oct;27(10):813-829. doi: 10.1089/hum.2016.068.

PMID:
27431943
9.

Three common pathways of nephrotoxicity induced by halogenated alkenes.

Cristofori P, Sauer AV, Trevisan A.

Cell Biol Toxicol. 2015 Feb;31(1):1-13. doi: 10.1007/s10565-015-9293-x. Epub 2015 Feb 11. Review.

PMID:
25665826
10.

Molecular biomarkers of phospholipidosis in rat blood and heart after amiodarone treatment.

Bocchini N, Giantin M, Crivellente F, Ferraresso S, Faustinelli I, Dacasto M, Cristofori P.

J Appl Toxicol. 2015 Jan;35(1):90-103.

PMID:
25580480
11.

Cocaine-associated increase of atrial natriuretic peptides: an early predictor of cardiac complications in cocaine users?

Casartelli A, Dacome L, Tessari M, Pascali J, Bortolotti F, Trevisan MT, Bosco O, Cristofori P, Tagliaro F.

Heart Asia. 2014 Jul 8;6(1):100-7. doi: 10.1136/heartasia-2013-010482. eCollection 2014.

12.

Spontaneous cardiomyopathy in young Sprague-Dawley rats: evaluation of biological and environmental variability.

Chanut F, Kimbrough C, Hailey R, Berridge B, Hughes-Earle A, Davies R, Roland K, Stokes A, Casartelli A, York M, Jordan H, Crivellente F, Cristofori P, Thomas H, Klapwijk J, Adler R.

Toxicol Pathol. 2013;41(8):1126-36. doi: 10.1177/0192623313478692. Epub 2013 Mar 7.

PMID:
23475560
13.

Expression of the aryl hydrocarbon receptor pathway and cyclooxygenase-2 in dog tumors.

Giantin M, Vascellari M, Lopparelli RM, Ariani P, Vercelli A, Morello EM, Cristofori P, Granato A, Buracco P, Mutinelli F, Dacasto M.

Res Vet Sci. 2013 Feb;94(1):90-9. doi: 10.1016/j.rvsc.2012.07.035. Epub 2012 Aug 24.

14.

Sex-related differences in renal toxicodynamics in rodents.

Trevisan A, Chiara F, Mongillo M, Quintieri L, Cristofori P.

Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1173-88. doi: 10.1517/17425255.2012.698262. Epub 2012 Jul 7. Review.

PMID:
22769852
15.

Atrial natriuretic peptides in Han Wistar, Sprague-Dawley and spontaneously hypertensive rats.

Crivellente F, Bocchini N, Bonato M, Vandin L, Faustinelli I, Cristofori P.

J Appl Toxicol. 2012 Jul;32(7):521-6. doi: 10.1002/jat.1759. Epub 2011 Nov 14.

PMID:
22083722
16.

A robust experimental protocol for pharmacological fMRI in rats and mice.

Ferrari L, Turrini G, Crestan V, Bertani S, Cristofori P, Bifone A, Gozzi A.

J Neurosci Methods. 2012 Feb 15;204(1):9-18. doi: 10.1016/j.jneumeth.2011.10.020. Epub 2011 Oct 28.

PMID:
22068031
17.

Hyaline droplet accumulation in kidney of rats treated with hexachloro-1:3-butadiene: influence of age, dose and time-course.

Cristofori P, Defazio R, Chiusolo A, Mongillo M, Bartolucci GB, Chiara F, Trevisan A.

J Appl Toxicol. 2013 Mar;33(3):183-9. doi: 10.1002/jat.1732. Epub 2011 Sep 13.

PMID:
21913211
18.

NT-proBNP as a biomarker for the assessment of a potential cardiovascular drug-induced liability in beagle dogs.

Crivellente F, Tontodonati M, Fasdelli N, Casartelli A, Dorigatti R, Faustinelli I, Cristofori P.

Cell Biol Toxicol. 2011 Dec;27(6):425-38. doi: 10.1007/s10565-011-9197-3. Epub 2011 Aug 8.

PMID:
21823034
19.

Neuroimaging evidence of altered fronto-cortical and striatal function after prolonged cocaine self-administration in the rat.

Gozzi A, Tessari M, Dacome L, Agosta F, Lepore S, Lanzoni A, Cristofori P, Pich EM, Corsi M, Bifone A.

Neuropsychopharmacology. 2011 Nov;36(12):2431-40. doi: 10.1038/npp.2011.129. Epub 2011 Jul 20.

20.

A novel and integrated approach for the identification and characterization of drug-induced cardiac toxicity in the dog.

Casartelli A, Lanzoni A, Comelli R, Crivellente F, Defazio R, Dorigatti R, Fasdelli N, Faustinelli I, Pagliarusco S, Tontodonati M, Cristofori P.

Toxicol Pathol. 2011 Feb;39(2):361-71. doi: 10.1177/0192623310390704. Epub 2010 Dec 14.

PMID:
21422262
21.

Localization of Helicobacter spp. in the fundic mucosa of laboratory Beagle dogs: an ultrastructural study.

Lanzoni A, Faustinelli I, Cristofori P, Luini M, Simpson KW, Scanziani E, Recordati C.

Vet Res. 2011 Mar 2;42:42. doi: 10.1186/1297-9716-42-42.

22.

Gold(III)-dithiocarbamato anticancer agents: activity, toxicology and histopathological studies in rodents.

Marzano C, Ronconi L, Chiara F, Giron MC, Faustinelli I, Cristofori P, Trevisan A, Fregona D.

Int J Cancer. 2011 Jul 15;129(2):487-96. doi: 10.1002/ijc.25684. Epub 2010 Nov 12.

23.

Industry survey of approaches to examination and terminology of spontaneous changes in the heart of young rats.

Keenan CM, Hughes-Earle AR, Maleeff BE, Thomas HC, Adler RR, Cristofori PG, Klapwijk JC.

Toxicol Pathol. 2010 Oct;38(6):995-8. doi: 10.1177/0192623310378868. Epub 2010 Aug 17. No abstract available.

PMID:
20716787
24.

Kidney injury molecule-1 expression in rat proximal tubule after treatment with segment-specific nephrotoxicants: a tool for early screening of potential kidney toxicity.

Chiusolo A, Defazio R, Zanetti E, Mongillo M, Mori N, Cristofori P, Trevisan A.

Toxicol Pathol. 2010 Apr;38(3):338-45. doi: 10.1177/0192623310362244. Epub 2010 Mar 19.

PMID:
20305092
25.

Evaluation of aging influence on renal toxicity caused by segment-specific nephrotoxicants of the proximal tubule in rat.

Zanetti E, Chiusolo A, Defazio R, Casartelli A, Cappelletti E, Bocchini N, Chiara F, Cristofori P, Trevisan A.

J Appl Toxicol. 2010 Mar;30(2):142-50. doi: 10.1002/jat.1480.

PMID:
19742859
26.

Capillary electrophoresis for the detection of bilirubin in rat serum.

Crivellente F, Bocchini N, Vandin L, Cristofori P.

Vet Clin Pathol. 2009 Sep;38(3):326-31. doi: 10.1111/j.1939-165X.2009.00121.x. Epub 2009 Apr 16.

PMID:
19392758
27.

Flow cytometry, with double staining with Nile red and anti-CD3 antibody, to detect phospholipidosis in peripheral blood lymphocytes of rats treated with amiodarone.

Perico ME, Crivellente F, Faustinelli I, Suozzi A, Cristofori P.

Cell Biol Toxicol. 2009 Dec;25(6):587-98. doi: 10.1007/s10565-008-9114-6. Epub 2008 Dec 23.

PMID:
19105033
28.

Regucalcin down-regulation in rat kidney tissue after treatment with nephrotoxicants.

Chiusolo A, Defazio R, Casartelli A, Bocchini N, Mongillo M, Zanetti E, Cristofori P, Trevisan A.

Toxicol Lett. 2008 Nov 10;182(1-3):84-90. doi: 10.1016/j.toxlet.2008.08.014. Epub 2008 Sep 2.

PMID:
18805471
29.

Analysis of mouse, rat, dog, marmoset, and human serum proteins by capillary electrophoresis: comparison with agarose gel electrophoresis.

Crivellente F, Bonato M, Cristofori P.

Vet Clin Pathol. 2008 Mar;37(1):73-8. doi: 10.1111/j.1939-165X.2008.00008.x.

PMID:
18366548
30.

Early onset of spontaneous renal preneoplastic and neoplastic lesions in young conventional rats in toxicity studies.

Lanzoni A, Piaia A, Everitt J, Faustinelli I, Defazio R, Cavaliere L, Cristofori P.

Toxicol Pathol. 2007 Jun;35(4):589-93.

PMID:
17654399
31.

Renal proximal tubule segment-specific nephrotoxicity: an overview on biomarkers and histopathology.

Cristofori P, Zanetti E, Fregona D, Piaia A, Trevisan A.

Toxicol Pathol. 2007 Feb;35(2):270-5.

PMID:
17366321
32.

(1)H MRI of pneumococcal pneumonia in a murine model.

Marzola P, Lanzoni A, Nicolato E, Di Modugno V, Cristofori P, Osculati F, Sbarbati A.

J Magn Reson Imaging. 2005 Jul;22(1):170-4.

PMID:
15971184
33.

Segmentary effects on the renal proximal tubule due to hexachloro-1,3-butadiene in rats: biomarkers related to gender.

Trevisan A, Cristofori P, Beggio M, Venturini MB, Di Marco L, Zanetti E.

J Appl Toxicol. 2005 Jan-Feb;25(1):13-9.

PMID:
15669050
34.

Involvement of the nitric oxide system in the anti-atherosclerotic potential of lacidipine in the ApoE-deficient mouse: a morphological, functional, and electrochemical study.

Cristofori PG, Crivellente FA, Faustinelli I, Lanzoni AR, Lazzarini C, Vecchiato E, Andreoli M, Turton JA, Zancanaro C, Crespi FM.

Toxicol Pathol. 2004 Jul-Aug;32(4):493-9.

PMID:
15223775
35.

Reduced progression of atherosclerosis in apolipoprotein E-deficient mice treated with lacidipine is associated with a decreased susceptibility of low-density lipoprotein to oxidation.

Cristofori P, Crivellente F, Campagnola M, Pasini AF, Garbin U, Rigoni A, Tosetti M, Turton J, Faustinelli I, Cominacini L.

Int J Exp Pathol. 2004 Apr;85(2):105-14.

36.

A cell-based approach for the early assessment of the phospholipidogenic potential in pharmaceutical research and drug development.

Casartelli A, Bonato M, Cristofori P, Crivellente F, Dal Negro G, Masotto I, Mutinelli C, Valko K, Bonfante V.

Cell Biol Toxicol. 2003 Jun;19(3):161-76.

PMID:
12945744
37.

[Integrated project for the translational research on pancreatic ductal carcinoma].

Marcucci S, Bonora A, Falconi M, Sorio C, Orlandini S, Beghelli S, Cristofori P, Dal Negro G, Marchiori PN, Bassi C, Scarpa A, Pederzoli P.

Chir Ital. 2002 Nov-Dec;54(6):845-54. Italian.

PMID:
12613334
38.

Chronic nicotine treatment changes the axonal distribution of 68 kDa neurofilaments in the rat ventral tegmental area.

Sbarbati A, Bunnemann B, Cristofori P, Terron A, Chiamulera C, Merigo F, Benati D, Bernardi P, Osculati F.

Eur J Neurosci. 2002 Sep;16(5):877-82.

PMID:
12372024
39.

Synthesis of a palladium(II)-dithiocarbamate complex: biological assay and nephrotoxicity in rats.

Trevisan A, Marzano C, Cristofori P, Borella Venturini M, Giovagnini L, Fregona D.

Arch Toxicol. 2002 Jun;76(5-6):262-8. Epub 2002 Apr 11.

PMID:
12107643
40.

Successful xenografting of cryopreserved primary pancreatic cancers.

Sorio C, Bonora A, Orlandini S, Moore PS, Capelli P, Cristofori P, Dal Negro G, Marchiori P, Gaviraghi G, Falconi M, Pederzoli P, Zamboni G, Scarpa A.

Virchows Arch. 2001 Feb;438(2):154-8.

PMID:
11253117
41.

The calcium-channel blocker lacidipine reduces the development of atherosclerotic lesions in the apoE-deficient mouse.

Cristofori P, Lanzoni A, Quartaroli M, Pastorino AM, Zancanaro C, Cominacini L, Gaviraghi G, Turton J.

J Hypertens. 2000 Oct;18(10):1429-36.

PMID:
11057430
42.

Anti-atherosclerotic activity of the calcium antagonist lacidipine in cholesterol-fed hamsters.

Cristofori P, Lanzoni A, Gaviraghi G, Turton J, Sbarbati A.

Biomed Pharmacother. 2000 Mar;54(2):93-9.

PMID:
10759293
43.

Comparison between MRI, microbiology and histology in evaluation of antibiotics in a murine model of thigh infection.

Marzola P, Nicolato E, Di Modugno E, Cristofori P, Lanzoni A, Ladel CH, Sbarbati A.

MAGMA. 1999 Oct;9(1-2):21-8.

PMID:
10555170
44.
45.

Glutamine transaminase K intranephron localization in rats determined by urinary excretion after treatment with segment-specific nephrotoxicants.

Trevisan A, Cristofori P, Fanelli G, Bicciato F, Stocco E.

Arch Toxicol. 1998 Jul-Aug;72(8):531-5.

PMID:
9765069
46.

Protective action of lacidipine in cardiac hypertrophy of the spontaneously hypertensive stroke-prone rat: an ultrastructural study.

Cristofori P, Sbarbati A, Accordini C, Terron A, Micheli D.

J Submicrosc Cytol Pathol. 1994 Jul;26(3):331-40.

PMID:
8087797
47.

Lacidipine: experimental evidence of vasculoprotective properties.

Cristofori P, Micheli D, Terron A, Gaviraghi G.

J Cardiovasc Pharmacol. 1994;23 Suppl 5:S90-3.

PMID:
7609515
48.

Qualitative and quantitative analysis of the progressive cerebral damage after middle cerebral artery occlusion in mice.

Chiamulera C, Terron A, Reggiani A, Cristofori P.

Brain Res. 1993 Mar 26;606(2):251-8.

PMID:
7683958
49.

Copper supplementation in the rat: preliminary observations on the clinical, hematological and histopathological profile.

Cristofori P, Terron A, Marella M, Moretti U, Pasqualicchio M, Velo GP, Milanino R.

Agents Actions. 1992;Spec No:C118-20.

PMID:
1442330
50.

Vascular protection of lacidipine in salt-loaded Dahl-S rats at nonsustained antihypertensive doses.

Cristofori P, Terron A, Micheli D, Bertolini G, Gaviraghi G, Carpi C.

J Cardiovasc Pharmacol. 1991;17 Suppl 4:S75-85; discussion S85-6.

PMID:
1726012

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