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Items: 42

1.

T-Cell-Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028.

Ott PA, Bang YJ, Piha-Paul SA, Razak ARA, Bennouna J, Soria JC, Rugo HS, Cohen RB, O'Neil BH, Mehnert JM, Lopez J, Doi T, van Brummelen EMJ, Cristescu R, Yang P, Emancipator K, Stein K, Ayers M, Joe AK, Lunceford JK.

J Clin Oncol. 2018 Dec 13:JCO2018782276. doi: 10.1200/JCO.2018.78.2276. [Epub ahead of print]

PMID:
30557521
2.

Molecular Profiling of Cohorts of Tumor Samples to Guide Clinical Development of Pembrolizumab as Monotherapy.

Ayers M, Nebozhyn M, Cristescu R, McClanahan TK, Perini R, Rubin E, Cheng JD, Kaufman DR, Loboda A.

Clin Cancer Res. 2018 Nov 15. doi: 10.1158/1078-0432.CCR-18-1316. [Epub ahead of print]

PMID:
30442684
3.

Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy.

Cristescu R, Mogg R, Ayers M, Albright A, Murphy E, Yearley J, Sher X, Liu XQ, Lu H, Nebozhyn M, Zhang C, Lunceford JK, Joe A, Cheng J, Webber AL, Ibrahim N, Plimack ER, Ott PA, Seiwert TY, Ribas A, McClanahan TK, Tomassini JE, Loboda A, Kaufman D.

Science. 2018 Oct 12;362(6411). pii: eaar3593. doi: 10.1126/science.aar3593.

4.

Clinical implication of tumor mutational burden in patients with HER2-positive refractory metastatic breast cancer.

Park SE, Park K, Lee E, Kim JY, Ahn JS, Im YH, Lee C, Jung H, Cho SY, Park WY, Cristescu R, Park YH.

Oncoimmunology. 2018 May 24;7(8):e1466768. doi: 10.1080/2162402X.2018.1466768. eCollection 2018.

PMID:
30221068
5.

Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer.

Kim ST, Cristescu R, Bass AJ, Kim KM, Odegaard JI, Kim K, Liu XQ, Sher X, Jung H, Lee M, Lee S, Park SH, Park JO, Park YS, Lim HY, Lee H, Choi M, Talasaz A, Kang PS, Cheng J, Loboda A, Lee J, Kang WK.

Nat Med. 2018 Sep;24(9):1449-1458. doi: 10.1038/s41591-018-0101-z. Epub 2018 Jul 16.

PMID:
30013197
6.

Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial.

Cho J, Kim HS, Ku BM, Choi YL, Cristescu R, Han J, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ.

J Clin Oncol. 2018 Jun 15:JCO2017773184. doi: 10.1200/JCO.2017.77.3184. [Epub ahead of print]

PMID:
29906252
7.

Fresh is best: Accurate SNP genotyping from koala scats.

Schultz AJ, Cristescu RH, Littleford-Colquhoun BL, Jaccoud D, Frère CH.

Ecol Evol. 2018 Feb 18;8(6):3139-3151. doi: 10.1002/ece3.3765. eCollection 2018 Mar.

8.

Development of mesenchymal subtype gene signature for clinical application in gastric cancer.

Lee J, Cristescu R, Kim KM, Kim K, Kim ST, Park SH, Kang WK.

Oncotarget. 2017 Aug 7;8(39):66305-66315. doi: 10.18632/oncotarget.19985. eCollection 2017 Sep 12.

9.

Using demographic characteristics of populations to detect spatial fragmentation following suspected ebola outbreaks in great apes.

Genton C, Cristescu R, Gatti S, Levréro F, Bigot E, Motsch P, Le Gouar P, Pierre JS, Ménard N.

Am J Phys Anthropol. 2017 Sep;164(1):3-10. doi: 10.1002/ajpa.23275. Epub 2017 Jun 29.

10.

Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity.

Guo Y, MacIsaac KD, Chen Y, Miller RJ, Jain R, Joyce-Shaikh B, Ferguson H, Wang IM, Cristescu R, Mudgett J, Engstrom L, Piers KJ, Baltus GA, Barr K, Zhang H, Mehmet H, Hegde LG, Hu X, Carter LL, Aicher TD, Glick G, Zaller D, Hawwari A, Correll CC, Jones DC, Cua DJ.

Cell Rep. 2016 Dec 20;17(12):3206-3218. doi: 10.1016/j.celrep.2016.11.073.

11.

Integrative analysis of diffusion-weighted MRI and genomic data to inform treatment of glioblastoma.

Jajamovich GH, Valiathan CR, Cristescu R, Somayajula S.

J Neurooncol. 2016 Sep;129(2):289-300. doi: 10.1007/s11060-016-2174-1. Epub 2016 Jul 8.

PMID:
27393347
12.

High Levels of Expression of P-glycoprotein/Multidrug Resistance Protein Result in Resistance to Vintafolide.

Guertin AD, O'Neil J, Stoeck A, Reddy JA, Cristescu R, Haines BB, Hinton MC, Dorton R, Bloomfield A, Nelson M, Vetzel M, Lejnine S, Nebozhyn M, Zhang T, Loboda A, Picard KL, Schmidt EV, Dussault I, Leamon CP.

Mol Cancer Ther. 2016 Aug;15(8):1998-2008. doi: 10.1158/1535-7163.MCT-15-0950. Epub 2016 Jun 2.

13.

An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies.

O'Neil J, Benita Y, Feldman I, Chenard M, Roberts B, Liu Y, Li J, Kral A, Lejnine S, Loboda A, Arthur W, Cristescu R, Haines BB, Winter C, Zhang T, Bloecher A, Shumway SD.

Mol Cancer Ther. 2016 Jun;15(6):1155-62. doi: 10.1158/1535-7163.MCT-15-0843. Epub 2016 Mar 16.

14.

Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination.

Fourati S, Cristescu R, Loboda A, Talla A, Filali A, Railkar R, Schaeffer AK, Favre D, Gagnon D, Peretz Y, Wang IM, Beals CR, Casimiro DR, Carayannopoulos LN, Sékaly RP.

Nat Commun. 2016 Jan 8;7:10369. doi: 10.1038/ncomms10369.

15.

[Endodontics in motion: new concepts, materials and techniques 1. Hydraulic Calcium Silicate Cements].

Moinzadeh AT, Jongsma L, de Groot-Kuin D, Cristescu R, Neirynck N, Camilleri J.

Ned Tijdschr Tandheelkd. 2015 Jul-Aug;122(7-8):405-14. doi: 10.5177/ntvt.2015.07/08.15146. Dutch.

PMID:
26210543
16.

Correction: Potential 'Ecological Traps' of Restored Landscapes: Koalas Phascolarctos cinereus Re-Occupy a Rehabilitated Mine Site.

Cristescu RH, Banks PB, Carrick FN, Frère C; PLOS ONE Staff.

PLoS One. 2015 Jun 9;10(6):e0130115. doi: 10.1371/journal.pone.0130115. eCollection 2015. No abstract available.

17.

Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.

Cristescu R, Lee J, Nebozhyn M, Kim KM, Ting JC, Wong SS, Liu J, Yue YG, Wang J, Yu K, Ye XS, Do IG, Liu S, Gong L, Fu J, Jin JG, Choi MG, Sohn TS, Lee JH, Bae JM, Kim ST, Park SH, Sohn I, Jung SH, Tan P, Chen R, Hardwick J, Kang WK, Ayers M, Hongyue D, Reinhard C, Loboda A, Kim S, Aggarwal A.

Nat Med. 2015 May;21(5):449-56. doi: 10.1038/nm.3850. Epub 2015 Apr 20.

PMID:
25894828
18.

Fabrication of magnetite-based core-shell coated nanoparticles with antibacterial properties.

Grumezescu AM, Cristescu R, Chifiriuc MC, Dorcioman G, Socol G, Mihailescu IN, Mihaiescu DE, Ficai A, Vasile OR, Enculescu M, Chrisey DB.

Biofabrication. 2015 Mar 23;7(1):015014. doi: 10.1088/1758-5090/7/1/015014.

PMID:
25797361
19.

Accuracy and efficiency of detection dogs: a powerful new tool for koala conservation and management.

Cristescu RH, Foley E, Markula A, Jackson G, Jones D, Frère C.

Sci Rep. 2015 Feb 10;5:8349. doi: 10.1038/srep08349.

20.

A sensitive A3B porphyrin nanomaterial for CO2 detection.

Fagadar-Cosma E, Vlascici D, Fagadar-Cosma G, Palade A, Lascu A, Creanga I, Birdeanu M, Cristescu R, Cernica I.

Molecules. 2014 Dec 17;19(12):21239-52. doi: 10.3390/molecules191221239.

21.

Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing.

Wong SS, Kim KM, Ting JC, Yu K, Fu J, Liu S, Cristescu R, Nebozhyn M, Gong L, Yue YG, Wang J, Ronghua C, Loboda A, Hardwick J, Liu X, Dai H, Jin JG, Ye XS, Kang SY, Do IG, Park JO, Sohn TS, Reinhard C, Lee J, Kim S, Aggarwal A.

Nat Commun. 2014 Nov 19;5:5477. doi: 10.1038/ncomms6477.

PMID:
25407104
22.

[Malyugin ring--an alternative in the treatment of a miotic pupil].

Muşat O, Mahdi L, Gheorghe A, Burcea M, Cernat C, Cristescu R, Toma O, Radu A.

Oftalmologia. 2014;58(2):40-2. Romanian.

PMID:
25300128
23.

How Ebola impacts social dynamics in gorillas: a multistate modelling approach.

Genton C, Pierre A, Cristescu R, Lévréro F, Gatti S, Pierre JS, Ménard N, Le Gouar P.

J Anim Ecol. 2015 Jan;84(1):166-76. doi: 10.1111/1365-2656.12268. Epub 2014 Jul 24.

PMID:
24995485
24.

Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique.

Holban AM, Grumezescu V, Grumezescu AM, Vasile BŞ, Truşcă R, Cristescu R, Socol G, Iordache F.

Beilstein J Nanotechnol. 2014 Jun 18;5:872-80. doi: 10.3762/bjnano.5.99. eCollection 2014.

25.

Potential 'ecological traps' of restored landscapes: koalas Phascolarctos cinereus re-occupy a rehabilitated mine site.

Cristescu RH, Banks PB, Carrick FN, Frère C.

PLoS One. 2013 Nov 25;8(11):e80469. doi: 10.1371/journal.pone.0080469. eCollection 2013. Erratum in: PLoS One. 2015;10(6):e0130115.

26.

Enamel pearls in permanent dentition: case report and micro-CT evaluation.

Versiani MA, Cristescu RC, Saquy PC, Pécora JD, de Sousa-Neto MD.

Dentomaxillofac Radiol. 2013;42(6):20120332. doi: 10.1259/dmfr.20120332. Epub 2013 Mar 21.

27.

[Ocular hypertension after surgery for retinal detachment].

Muşat O, Cristescu R, Coman C, Asandi R.

Oftalmologia. 2012;56(2):40-2. Romanian.

PMID:
23424762
28.

[Penetrating ocular trauma with intraocular foreign body--surgical resolution].

Musat O, Coman C, Ochinciuc U, Gutu T, Cristescu R, Asandi R.

Oftalmologia. 2012;56(2):30-3. Romanian. No abstract available.

PMID:
23424760
29.

[Retinal detachment with retinoschisis--case report].

Cristescu R, Muşat O, Toma O, Coma C, Gabej I, Burcea M.

Oftalmologia. 2013;57(4):17-21. Romanian.

PMID:
24844032
30.

[Clinical and functional considerations in some cases of postoperative endophthalmitis].

Muşat O, Toma O, Cristescu R, Coman C, Asandi R, Burcea M.

Oftalmologia. 2013;57(4):9-16. Romanian.

PMID:
24844031
31.

Functionalized magnetite silica thin films fabricated by MAPLE with antibiofilm properties.

Mihaiescu DE, Cristescu R, Dorcioman G, Popescu CE, Nita C, Socol G, Mihailescu IN, Grumezescu AM, Tamas D, Enculescu M, Negrea RF, Ghica C, Chifiriuc C, Bleotu C, Chrisey DB.

Biofabrication. 2013 Mar;5(1):015007. doi: 10.1088/1758-5082/5/1/015007. Epub 2012 Dec 20.

PMID:
23254399
32.

Scientific investigations into febrile reactions observed in the paediatric population following vaccination with a 2010 Southern Hemisphere Trivalent Influenza Vaccine.

Maraskovsky E, Rockman S, Dyson A, Koernig S, Becher D, Morelli AB, Barnden M, Camuglia S, Bodle J, Vandenberg K, Wang IM, Cristescu R, Loboda A, Citron M, Fontenot J, Hung D, Schoofs P, Pearse M.

Vaccine. 2012 Dec 7;30(51):7400-6. doi: 10.1016/j.vaccine.2012.09.083. Epub 2012 Oct 9.

PMID:
23063831
33.

Recovery potential of a western lowland gorilla population following a major Ebola outbreak: results from a ten year study.

Genton C, Cristescu R, Gatti S, Levréro F, Bigot E, Caillaud D, Pierre JS, Ménard N.

PLoS One. 2012;7(5):e37106. doi: 10.1371/journal.pone.0037106. Epub 2012 May 23.

34.

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.

Rasmussen AL, Wang IM, Shuhart MC, Proll SC, He Y, Cristescu R, Roberts C, Carter VS, Williams CM, Diamond DL, Bryan JT, Ulrich R, Korth MJ, Thomassen LV, Katze MG.

Virology. 2012 Aug 15;430(1):43-52. doi: 10.1016/j.virol.2012.04.011. Epub 2012 May 16.

35.

[Intraocular hypertension after retinal detachment surgery].

Muşat O, Cristescu R, Coman C, Asandi R.

Oftalmologia. 2012;56(4):71-3. Romanian.

PMID:
23755521
36.

[Contusive ocular trauma--case report].

Muşat O, Coman C, Cristescu R, Asandi R.

Oftalmologia. 2012;56(4):54-8. Romanian.

PMID:
23755518
37.

[Clinical and functional considerations in some cases of postoperative endophthalmitis].

Muşat O, Marinescu O, Cristescu R, Coman C, Asandi R.

Oftalmologia. 2012;56(4):45-53. Romanian.

PMID:
23755517
38.

Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates.

Wang IM, Bett AJ, Cristescu R, Loboda A, ter Meulen J.

Microb Biotechnol. 2012 Mar;5(2):177-87. doi: 10.1111/j.1751-7915.2011.00317.x. Epub 2011 Nov 22. Review.

39.

The use of cone-beam computed tomography and digital periapical radiographs to diagnose root perforations.

Shemesh H, Cristescu RC, Wesselink PR, Wu MK.

J Endod. 2011 Apr;37(4):513-6. doi: 10.1016/j.joen.2010.12.003. Epub 2011 Feb 25.

PMID:
21419300
40.

[Rhegmatogenous retinal detachment--clinical case].

Muşat O, Cristescu R, Ochinciuc U, Guţu T, Coman C, Asandi R.

Oftalmologia. 2011;55(4):70-4. Romanian.

PMID:
22642139
41.

Positive allosteric interaction of structurally diverse T-type calcium channel antagonists.

Uebele VN, Nuss CE, Fox SV, Garson SL, Cristescu R, Doran SM, Kraus RL, Santarelli VP, Li Y, Barrow JC, Yang ZQ, Schlegel KA, Rittle KE, Reger TS, Bednar RA, Lemaire W, Mullen FA, Ballard JE, Tang C, Dai G, McManus OB, Koblan KS, Renger JJ.

Cell Biochem Biophys. 2009;55(2):81-93. doi: 10.1007/s12013-009-9057-4. Epub 2009 Jul 7.

PMID:
19582593
42.

Gorilla susceptibility to Ebola virus: the cost of sociality.

Caillaud D, Levréro F, Cristescu R, Gatti S, Dewas M, Douadi M, Gautier-Hion A, Raymond M, Ménard N.

Curr Biol. 2006 Jul 11;16(13):R489-91. No abstract available.

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