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Items: 18


Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage.

Hingorani DV, Lippert CN, Crisp JL, Savariar EN, Hasselmann JPC, Kuo C, Nguyen QT, Tsien RY, Whitney MA, Ellies LG.

PLoS One. 2018 Sep 24;13(9):e0198464. doi: 10.1371/journal.pone.0198464. eCollection 2018.


Nerve-targeted probes for fluorescence-guided intraoperative imaging.

Hingorani DV, Whitney MA, Friedman B, Kwon JK, Crisp JL, Xiong Q, Gross L, Kane CJ, Tsien RY, Nguyen QT.

Theranostics. 2018 Jul 30;8(15):4226-4237. doi: 10.7150/thno.23084. eCollection 2018.


Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization.

Glasgow HL, Whitney MA, Gross LA, Friedman B, Adams SR, Crisp JL, Hussain T, Frei AP, Novy K, Wollscheid B, Nguyen QT, Tsien RY.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12774-12779. doi: 10.1073/pnas.1611642113. Epub 2016 Oct 20.


Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize.

Adams SR, Yang HC, Savariar EN, Aguilera J, Crisp JL, Jones KA, Whitney MA, Lippman SM, Cohen EE, Tsien RY, Advani SJ.

Nat Commun. 2016 Oct 4;7:13019. doi: 10.1038/ncomms13019.


A far-red fluorescent protein evolved from a cyanobacterial phycobiliprotein.

Rodriguez EA, Tran GN, Gross LA, Crisp JL, Shu X, Lin JY, Tsien RY.

Nat Methods. 2016 Sep;13(9):763-9. doi: 10.1038/nmeth.3935. Epub 2016 Aug 1.


New Dioxaborolane Chemistry Enables [(18)F]-Positron-Emitting, Fluorescent [(18)F]-Multimodality Biomolecule Generation from the Solid Phase.

Rodriguez EA, Wang Y, Crisp JL, Vera DR, Tsien RY, Ting R.

Bioconjug Chem. 2016 May 18;27(5):1390-1399. doi: 10.1021/acs.bioconjchem.6b00164. Epub 2016 Apr 27.


Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery.

Buckel L, Savariar EN, Crisp JL, Jones KA, Hicks AM, Scanderbeg DJ, Nguyen QT, Sicklick JK, Lowy AM, Tsien RY, Advani SJ.

Cancer Res. 2015 Apr 1;75(7):1376-1387. doi: 10.1158/0008-5472.CAN-14-1931. Epub 2015 Feb 13.


Dual targeting of integrin αvβ3 and matrix metalloproteinase-2 for optical imaging of tumors and chemotherapeutic delivery.

Crisp JL, Savariar EN, Glasgow HL, Ellies LG, Whitney MA, Tsien RY.

Mol Cancer Ther. 2014 Jun;13(6):1514-25. doi: 10.1158/1535-7163.MCT-13-1067. Epub 2014 Apr 15.


Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation.

Whitney M, Savariar EN, Friedman B, Levin RA, Crisp JL, Glasgow HL, Lefkowitz R, Adams SR, Steinbach P, Nashi N, Nguyen QT, Tsien RY.

Angew Chem Int Ed Engl. 2013 Jan 2;52(1):325-30. doi: 10.1002/anie.201205721. Epub 2012 Oct 18.


In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity.

Olson ES, Whitney MA, Friedman B, Aguilera TA, Crisp JL, Baik FM, Jiang T, Baird SM, Tsimikas S, Tsien RY, Nguyen QT.

Integr Biol (Camb). 2012 Jun;4(6):595-605. doi: 10.1039/c2ib00161f. Epub 2012 Apr 26.


Spiers Memorial Lecture. Breeding and building molecular spies.

Shu X, Lev-Ram V, Olson ES, Aguilera TA, Jiang T, Whitney M, Crisp JL, Steinbach P, Deerinck T, Ellisman MH, Ellies LG, Nguyen QT, Tsien RY.

Faraday Discuss. 2011;149:9; discussion 63-77.


Antisolvent crystallization of pharmaceutical excipients from aqueous solutions and the use of preferred orientation in phase identification by powder X-ray diffraction.

Crisp JL, Dann SE, Blatchford CG.

Eur J Pharm Sci. 2011 Apr 18;42(5):568-77. doi: 10.1016/j.ejps.2011.02.010. Epub 2011 Mar 5.


Improved facial nerve identification with novel fluorescently labeled probe.

Wu AP, Whitney MA, Crisp JL, Friedman B, Tsien RY, Nguyen QT.

Laryngoscope. 2011 Apr;121(4):805-10. doi: 10.1002/lary.21411. Epub 2011 Feb 16.


Fluorescent peptides highlight peripheral nerves during surgery in mice.

Whitney MA, Crisp JL, Nguyen LT, Friedman B, Gross LA, Steinbach P, Tsien RY, Nguyen QT.

Nat Biotechnol. 2011 Apr;29(4):352-6. doi: 10.1038/nbt.1764. Epub 2011 Feb 6.


Fast 18F labeling of a near-infrared fluorophore enables positron emission tomography and optical imaging of sentinel lymph nodes.

Ting R, Aguilera TA, Crisp JL, Hall DJ, Eckelman WC, Vera DR, Tsien RY.

Bioconjug Chem. 2010 Oct 20;21(10):1811-9. doi: 10.1021/bc1001328.


The in-situ solid-state NMR spectroscopy investigation of alcoholic lactose suspensions.

Crisp JL, Dann SE, Edgar M, Blatchford CG.

Solid State Nucl Magn Reson. 2010 May-Jun;37(3-4):75-81. doi: 10.1016/j.ssnmr.2010.05.001. Epub 2010 May 25.


Parallel in vivo and in vitro selection using phage display identifies protease-dependent tumor-targeting peptides.

Whitney M, Crisp JL, Olson ES, Aguilera TA, Gross LA, Ellies LG, Tsien RY.

J Biol Chem. 2010 Jul 16;285(29):22532-41. doi: 10.1074/jbc.M110.138297. Epub 2010 May 11.


The effect of particle size on the dehydration/rehydration behaviour of lactose.

Crisp JL, Dann SE, Edgar M, Blatchford CG.

Int J Pharm. 2010 May 31;391(1-2):38-47. doi: 10.1016/j.ijpharm.2010.02.012. Epub 2010 Feb 13.


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