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Intraperitoneal cannabidiol attenuates neonatal germinal matrix hemorrhage-induced neuroinflamation and perilesional apoptosis.

Abrantes De Lacerda Almeida T, Santos MV, Da Silva Lopes L, Goel G, Leonardo De Freitas R, De Medeiros P, Crippa JA, Machado HR.

Neurol Res. 2019 Aug 5:1-11. doi: 10.1080/01616412.2019.1651487. [Epub ahead of print]


Biological bases for a possible effect of cannabidiol in Parkinson's disease.

Ferreira-Junior NC, Campos AC, Guimarães FS, Del-Bel E, Zimmermann PMDR, Brum Junior L, Hallak JE, Crippa JA, Zuardi AW.

Braz J Psychiatry. 2019 Jul 15. pii: S1516-44462019005012104. doi: 10.1590/1516-4446-2019-0460. [Epub ahead of print]


Compliance to Adjuvant Chemotherapy of Patients Who Underwent Surgery for Rectal Cancer: Report from a Multi-institutional Research Network.

Mari GM, Maggioni D, Crippa J, Costanzi ATM, Scotti MA, Giardini V, Garancini M, Cocozza E, Borroni G, Benzoni I, Martinotti M, Totaro L, Origi M, Mazzola M, Ferrari G, Achilli P, Ziccarelli A, Martino A, Petri R, Botta F, Bagnardi V, Pugliese G, Forgione A, Pugliese R; AIMS Academy Clinical Research Network.

World J Surg. 2019 Jun 25. doi: 10.1007/s00268-019-05060-5. [Epub ahead of print]


Personality Inventory for DSM-5 (PID-5): cross-cultural adaptation and content validity in the Brazilian context.

Barchi-Ferreira AM, Loureiro SR, Torres AR, da Silva TDA, Moreno AL, DeSousa DA, Chagas MHN, Dos Santos RG, Machado-de-Souza JP, Chagas NMS, Hallak JEC, Crippa JAS, Osório FL.

Trends Psychiatry Psychother. 2019 May 30. pii: S2237-60892019005004105. doi: 10.1590/2237-6089-2018-0098. [Epub ahead of print]


Hybrid minimally invasive/open approach versus total minimally invasive approach for rectal cancer resection: short- and long-term results.

Deidda S, Crippa J, Duchalais E, Kelley SR, Mathis KL, Dozois EJ, Larson DW.

Int J Colorectal Dis. 2019 Jul;34(7):1251-1258. doi: 10.1007/s00384-019-03311-4. Epub 2019 May 28.


Symptomatic Uncomplicated Diverticular Disease and Incidence of Unexpected Abscess during Sigmoidectomy: A Multicenter Prospective Observational Study.

Mari GM, Crippa J, Borroni G, Cocozza E, Roscio F, Scandroglio I, Origi M, Ferrari G, Forgione A, Riggio V, Pugliese R, Costanzi ATM, Maggioni D; on behalf of the AIMS Academy Clinical Research Network.

Dig Surg. 2019 May 22:1-6. doi: 10.1159/000500084. [Epub ahead of print]


Role of the endocannabinoid and endovanilloid systems in an animal model of schizophrenia-related emotional processing/cognitive deficit.

Almeida V, Levin R, Peres FF, Suiama MA, Vendramini AM, Santos CM, Silva ND, Zuardi AW, Hallak JEC, Crippa JA, Abílio VC.

Neuropharmacology. 2019 Sep 1;155:44-53. doi: 10.1016/j.neuropharm.2019.05.015. Epub 2019 May 16.


Low Ligation of Inferior Mesenteric Artery in Laparoscopic Anterior Resection for Rectal Cancer Reduces Genitourinary Dysfunction: Results From a Randomized Controlled Trial (HIGHLOW Trial).

Mari GM, Crippa J, Cocozza E, Berselli M, Livraghi L, Carzaniga P, Valenti F, Roscio F, Ferrari G, Mazzola M, Magistro C, Origi M, Forgione A, Zuliani W, Scandroglio I, Pugliese R, Costanzi ATM, Maggioni D.

Ann Surg. 2019 Jun;269(6):1018-1024. doi: 10.1097/SLA.0000000000002947.


Serotonergic hallucinogens and recognition of facial emotion expressions: a systematic review of the literature.

Rocha JM, Osório FL, Crippa JAS, Bouso JC, Rossi GN, Hallak JEC, Dos Santos RG.

Ther Adv Psychopharmacol. 2019 Apr 26;9:2045125319845774. doi: 10.1177/2045125319845774. eCollection 2019. Review.


Endoscopic Treatment of Anastomotic Bleeding in Laparoscopic Colorectal Surgery.

Mari G, Costanzi A, Crippa J, Berardi V, Santurro L, Gerosa M, Maggioni D.

Chirurgia (Bucur). 2019 Mar-Apr;114(2):295-299. doi: 10.21614/chirurgia.114.2.295.


The prevalence and clinical correlates of cannabis use and cannabis use disorder among patients with bipolar disorder: A systematic review with meta-analysis and meta-regression.

Pinto JV, Medeiros LS, Santana da Rosa G, Santana de Oliveira CE, Crippa JAS, Passos IC, Kauer-Sant'Anna M.

Neurosci Biobehav Rev. 2019 Jun;101:78-84. doi: 10.1016/j.neubiorev.2019.04.004. Epub 2019 Apr 8.


Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors.

Jesus CHA, Redivo DDB, Gasparin AT, Sotomaior BB, de Carvalho MC, Genaro K, Zuardi AW, Hallak JEC, Crippa JA, Zanoveli JM, da Cunha JM.

Brain Res. 2019 Jul 15;1715:156-164. doi: 10.1016/j.brainres.2019.03.014. Epub 2019 Mar 18.


Feasibility and safety of robotic resection of complicated diverticular disease.

Grass F, Crippa J, Mathis KL, Kelley SR, Larson DW.

Surg Endosc. 2019 Mar 13. doi: 10.1007/s00464-019-06727-9. [Epub ahead of print]


Impact of enhanced recovery on oncological outcomes following minimally invasive surgery for rectal cancer.

Quiram BJ, Crippa J, Grass F, Lovely JK, Behm KT, Colibaseanu DT, Merchea A, Kelley SR, Harmsen WS, Larson DW.

Br J Surg. 2019 Jun;106(7):922-929. doi: 10.1002/bjs.11131. Epub 2019 Mar 12.


DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor.

Silva RL, Silveira GT, Wanderlei CW, Cecilio NT, Maganin AGM, Franchin M, Marques LMM, Lopes NP, Crippa JA, Guimarães FS, Alves-Filho JCF, Cunha FQ, Cunha TM.

Toxicol Appl Pharmacol. 2019 Apr 1;368:63-71. doi: 10.1016/j.taap.2019.02.011. Epub 2019 Feb 20.


Is cannabidiol the ideal drug to treat non-motor Parkinson's disease symptoms?

Crippa JAS, Hallak JEC, Zuardi AW, Guimarães FS, Tumas V, Dos Santos RG.

Eur Arch Psychiatry Clin Neurosci. 2019 Feb;269(1):121-133. doi: 10.1007/s00406-019-00982-6. Epub 2019 Jan 31. Review.


Early Acute Kidney Injury Within an Established Enhanced Recovery Pathway: Uncommon and Transitory.

Grass F, Lovely JK, Crippa J, Mathis KL, Hübner M, Larson DW.

World J Surg. 2019 May;43(5):1207-1215. doi: 10.1007/s00268-019-04923-1.


Comparison of recovery and outcome after left and right colectomy.

Grass F, Lovely JK, Crippa J, Ansell J, Hübner M, Mathis KL, Larson DW.

Colorectal Dis. 2019 Apr;21(4):481-486. doi: 10.1111/codi.14543. Epub 2019 Jan 18.


Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma.

Vuolo F, Abreu SC, Michels M, Xisto DG, Blanco NG, Hallak JE, Zuardi AW, Crippa JA, Reis C, Bahl M, Pizzichinni E, Maurici R, Pizzichinni MMM, Rocco PRM, Dal-Pizzol F.

Eur J Pharmacol. 2019 Jan 15;843:251-259. doi: 10.1016/j.ejphar.2018.11.029. Epub 2018 Nov 24.


Epigenetic variation at the SLC6A4 gene promoter in mother-child pairs with major depressive disorder.

Mendonça MS, Mangiavacchi PM, De Sousa PF, Crippa JAS, Mendes AV, Loureiro SR, Martín-Santos R, Quirino CR, Kanashiro MM, Rios AFL.

J Affect Disord. 2019 Feb 15;245:716-723. doi: 10.1016/j.jad.2018.10.369. Epub 2018 Nov 6.


Ordering a Normal Diet at the End of Surgery-Justified or Overhasty?

Grass F, Hübner M, Lovely JK, Crippa J, Mathis KL, Larson DW.

Nutrients. 2018 Nov 14;10(11). pii: E1758. doi: 10.3390/nu10111758.


Possible Interactions Between 5-HT2A Receptors and the Endocannabinoid System in Humans: Preliminary Evidence of Interactive Effects of Ayahuasca and Endocannabinoids in a Healthy Human Subject.

Dos Santos RG, Crippa JA, Osório FL, Rocha JM, Rossi GN, Marchioni C, Queiroz MEC, Silveira GO, Yonamine M, Hallak JEC.

J Clin Psychopharmacol. 2018 Dec;38(6):644-646. doi: 10.1097/JCP.0000000000000973. No abstract available.


Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test.

Linares IM, Zuardi AW, Pereira LC, Queiroz RH, Mechoulam R, Guimarães FS, Crippa JA.

Braz J Psychiatry. 2019 Jan-Feb;41(1):9-14. doi: 10.1590/1516-4446-2017-0015. Epub 2018 Oct 11.


Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.

Crippa JA, Guimarães FS, Campos AC, Zuardi AW.

Front Immunol. 2018 Sep 21;9:2009. doi: 10.3389/fimmu.2018.02009. eCollection 2018. Review.


Cannabidiol Administered During Peri-Adolescence Prevents Behavioral Abnormalities in an Animal Model of Schizophrenia.

Peres FF, Diana MC, Levin R, Suiama MA, Almeida V, Vendramini AM, Santos CM, Zuardi AW, Hallak JEC, Crippa JA, Abílio VC.

Front Pharmacol. 2018 Aug 21;9:901. doi: 10.3389/fphar.2018.00901. eCollection 2018.


Surgical Stress Response and Enhanced Recovery after Laparoscopic Surgery - A systematic review.

Crippa J, Mari GM, Miranda A, Costanzi AT, Maggioni D.

Chirurgia (Bucur). 2018 Jul-Aug;113(4):455-463. doi: 10.21614/chirurgia.113.4.455.


Cross-cultural adaptation and psychometric assessment of a Brazilian-Portuguese version of the Resident Questionnaire.

Pereira-Lima K, Silva-Rodrigues APC, Marucci FAF, Osório FL, Crippa JA, Loureiro SR.

PLoS One. 2018 Sep 4;13(9):e0203531. doi: 10.1371/journal.pone.0203531. eCollection 2018.


Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.

da Silva VK, de Freitas BS, Garcia RCL, Monteiro RT, Hallak JE, Zuardi AW, Crippa JAS, Schröder N.

Transl Psychiatry. 2018 Sep 3;8(1):176. doi: 10.1038/s41398-018-0232-5.


Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System.

Schonhofen P, Bristot IJ, Crippa JA, Hallak JEC, Zuardi AW, Parsons RB, Klamt F.

CNS Drugs. 2018 Aug;32(8):697-712. doi: 10.1007/s40263-018-0550-4.


Low Ligation of Inferior Mesenteric Artery in Laparoscopic Anterior Resection for Rectal Cancer Reduces Genitourinary Dysfunction: Results From a Randomized Controlled Trial (HIGHLOW Trial).

Mari GM, Crippa J, Cocozza E, Berselli M, Livraghi L, Carzaniga P, Valenti F, Roscio F, Ferrari G, Mazzola M, Magistro C, Origi M, Forgione A, Zuliani W, Scandroglio I, Pugliese R, Costanzi ATM, Maggioni D.

Ann Surg. 2018 Jul 10. doi: 10.1097/SLA.0000000000002947. [Epub ahead of print]


Clinical issues in cannabis use.

Bonomo Y, Souza JDS, Jackson A, Crippa JAS, Solowij N.

Br J Clin Pharmacol. 2018 Nov;84(11):2495-2498. doi: 10.1111/bcp.13703. Epub 2018 Aug 17. Review.


Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos.

Valim Brigante TA, Abe FR, Zuardi AW, Hallak JEC, Crippa JAS, de Oliveira DP.

Chem Biol Interact. 2018 Aug 1;291:81-86. doi: 10.1016/j.cbi.2018.06.008. Epub 2018 Jun 11.


Sub-chronic treatment with cannabidiol but not with URB597 induced a mild antidepressant-like effect in diabetic rats.

de Morais H, Chaves YC, Waltrick APF, Jesus CHA, Genaro K, Crippa JA, da Cunha JM, Zanoveli JM.

Neurosci Lett. 2018 Aug 24;682:62-68. doi: 10.1016/j.neulet.2018.06.006. Epub 2018 Jun 6.


Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders?

Peres FF, Lima AC, Hallak JEC, Crippa JA, Silva RH, Abílio VC.

Front Pharmacol. 2018 May 11;9:482. doi: 10.3389/fphar.2018.00482. eCollection 2018. Review.


No Acute Effects of Cannabidiol on the Sleep-Wake Cycle of Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.

Linares IMP, Guimaraes FS, Eckeli A, Crippa ACS, Zuardi AW, Souza JDS, Hallak JE, Crippa JAS.

Front Pharmacol. 2018 Apr 5;9:315. doi: 10.3389/fphar.2018.00315. eCollection 2018.


Sodium nitroprusside is effective in preventing and/or reversing the development of schizophrenia-related behaviors in an animal model: The SHR strain.

Diana MC, Peres FF, Justi V, Bressan RA, Lacerda ALT, Crippa JA, Hallak JEC, Abilio VC.

CNS Neurosci Ther. 2018 Jul;24(7):624-632. doi: 10.1111/cns.12852. Epub 2018 Apr 14.


Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model.

Callejas GH, Figueira RL, Gonçalves FLL, Volpe FAP, Zuardi AW, Crippa JA, Hallak JE, Sbragia L.

Braz J Med Biol Res. 2018 Mar 15;51(5):e7132. doi: 10.1590/1414-431X20177132.


Author Correction: Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey.

Lawn W, Hallak JE, Crippa JA, Dos Santos R, Porffy L, Barratt MJ, Ferris JA, Winstock AR, Morgan CJA.

Sci Rep. 2018 Mar 1;8(1):4059. doi: 10.1038/s41598-018-21666-6.


The Influence of DAT1, COMT, and BDNF Genetic Polymorphisms on Total and Subregional Hippocampal Volumes in Early Onset Heavy Cannabis Users.

Batalla A, Lorenzetti V, Chye Y, Yücel M, Soriano-Mas C, Bhattacharyya S, Torrens M, Crippa JAS, Martín-Santos R.

Cannabis Cannabinoid Res. 2018 Feb 1;3(1):1-10. doi: 10.1089/can.2017.0021. eCollection 2018.


Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: Reversal by cannabidiol.

da Silva VK, de Freitas BS, Dornelles VC, Kist LW, Bogo MR, Silva MC, Streck EL, Hallak JE, Zuardi AW, Crippa JAS, Schröder N.

Brain Res Bull. 2018 May;139:1-8. doi: 10.1016/j.brainresbull.2018.01.014. Epub 2018 Jan 31.


Intracorporeal Anastomosis Reduces Surgical Stress Response in Laparoscopic Right Hemicolectomy: A Prospective Randomized Trial.

Mari GM, Crippa J, Costanzi ATM, Pellegrino R, Siracusa C, Berardi V, Maggioni D.

Surg Laparosc Endosc Percutan Tech. 2018 Apr;28(2):77-81. doi: 10.1097/SLE.0000000000000506.


Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey.

Lawn W, Hallak JE, Crippa JA, Dos Santos R, Porffy L, Barratt MJ, Ferris JA, Winstock AR, Morgan CJA.

Sci Rep. 2017 Nov 9;7(1):15201. doi: 10.1038/s41598-017-14700-6. Erratum in: Sci Rep. 2018 Mar 1;8(1):4059.


A Conversion of Oral Cannabidiol to Delta9-Tetrahydrocannabinol Seems Not to Occur in Humans.

Nahler G, Grotenhermen F, Zuardi AW, Crippa JAS.

Cannabis Cannabinoid Res. 2017 May 1;2(1):81-86. doi: 10.1089/can.2017.0009. eCollection 2017.


Cannabidiol Is a Potential Therapeutic for the Affective-Motivational Dimension of Incision Pain in Rats.

Genaro K, Fabris D, Arantes ALF, Zuardi AW, Crippa JAS, Prado WA.

Front Pharmacol. 2017 Jun 21;8:391. doi: 10.3389/fphar.2017.00391. eCollection 2017.


Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life.

Zuardi AW, Rodrigues NP, Silva AL, Bernardo SA, Hallak JEC, Guimarães FS, Crippa JAS.

Front Pharmacol. 2017 May 11;8:259. doi: 10.3389/fphar.2017.00259. eCollection 2017.


Assessing the Psychedelic "After-Glow" in Ayahuasca Users: Post-Acute Neurometabolic and Functional Connectivity Changes Are Associated with Enhanced Mindfulness Capacities.

Sampedro F, de la Fuente Revenga M, Valle M, Roberto N, Domínguez-Clavé E, Elices M, Luna LE, Crippa JAS, Hallak JEC, de Araujo DB, Friedlander P, Barker SA, Álvarez E, Soler J, Pascual JC, Feilding A, Riba J.

Int J Neuropsychopharmacol. 2017 Sep 1;20(9):698-711. doi: 10.1093/ijnp/pyx036.


Laparoscopic Surgery in Patients on Peritoneal Dialysis: A Review of the Literature.

Mari G, Scanziani R, Auricchio S, Crippa J, Maggioni D.

Surg Innov. 2017 Aug;24(4):397-401. doi: 10.1177/1553350617708723. Epub 2017 May 13. Review.


Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy.

Do Val-da Silva RA, Peixoto-Santos JE, Kandratavicius L, De Ross JB, Esteves I, De Martinis BS, Alves MN, Scandiuzzi RC, Hallak JE, Zuardi AW, Crippa JA, Leite JP.

Front Pharmacol. 2017 Mar 17;8:131. doi: 10.3389/fphar.2017.00131. eCollection 2017.


Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits.

Rossignoli MT, Lopes-Aguiar C, Ruggiero RN, Do Val da Silva RA, Bueno-Junior LS, Kandratavicius L, Peixoto-Santos JE, Crippa JA, Cecilio Hallak JE, Zuardi AW, Szawka RE, Anselmo-Franci J, Leite JP, Romcy-Pereira RN.

Neuroscience. 2017 May 14;350:85-93. doi: 10.1016/j.neuroscience.2017.03.019. Epub 2017 Mar 24.


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