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Items: 33


Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST).

Artaraz A, Crichton ML, Finch S, Abo-Leyah H, Goeminne P, Aliberti S, Fardon T, Chalmers JD.

Respir Res. 2020 Jan 13;21(1):18. doi: 10.1186/s12931-019-1272-y.


Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis.

Chalmers JD, Boersma W, Lonergan M, Jayaram L, Crichton ML, Karalus N, Taylor SL, Martin ML, Burr LD, Wong C, Altenburg J.

Lancet Respir Med. 2019 Oct;7(10):845-854. doi: 10.1016/S2213-2600(19)30191-2. Epub 2019 Aug 9.


The efficacy and safety of inhaled antibiotics for the treatment of bronchiectasis in adults: a systematic review and meta-analysis.

Laska IF, Crichton ML, Shoemark A, Chalmers JD.

Lancet Respir Med. 2019 Oct;7(10):855-869. doi: 10.1016/S2213-2600(19)30185-7. Epub 2019 Aug 9.


Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry.

Dhar R, Singh S, Talwar D, Mohan M, Tripathi SK, Swarnakar R, Trivedi S, Rajagopala S, D'Souza G, Padmanabhan A, Baburao A, Mahesh PA, Ghewade B, Nair G, Jindal A, Jayadevappa GDH, Sawhney H, Sarmah KR, Saha K, Anantharaj S, Khanna A, Gami S, Shah A, Shah A, Dutt N, Garg H, Vyas S, Venugopal K, Prasad R, Aleemuddin NM, Karmakar S, Singh V, Jindal SK, Sharma S, Prajapat D, Chandrashekaria S, McDonnell MJ, Mishra A, Rutherford R, Ramanathan RP, Goeminne PC, Vasudev P, Dimakou K, Crichton ML, Jayaraj BS, Kungwani R, Das A, Sawhney M, Polverino E, Torres A, Gulecha NS, Shteinberg M, De Soyza A, Mangala A, Shah P, Chauhan NK, Jajodia N, Singhal A, Batra S, Hasan A, Limaye S, Salvi S, Aliberti S, Chalmers JD.

Lancet Glob Health. 2019 Sep;7(9):e1269-e1279. doi: 10.1016/S2214-109X(19)30327-4. Erratum in: Lancet Glob Health. 2019 Dec;7(12):e1621.


Cellular metabolism and pore lifetime of human skin following microprojection array mediation.

Haridass IN, Wei JCJ, Mohammed YH, Crichton ML, Anderson CD, Henricson J, Sanchez WY, Meliga SC, Grice JE, Benson HAE, Kendall MAF, Roberts MS.

J Control Release. 2019 Jul 28;306:59-68. doi: 10.1016/j.jconrel.2019.05.024. Epub 2019 May 21.


Pulmonary rehabilitation after exacerbation of bronchiectasis: a pilot randomized controlled trial.

Chalmers JD, Crichton ML, Brady G, Finch S, Lonergan M, Fardon TC.

BMC Pulm Med. 2019 May 6;19(1):85. doi: 10.1186/s12890-019-0856-0.


A low inflammatory, Langerhans cell-targeted microprojection patch to deliver ovalbumin to the epidermis of mouse skin.

van der Burg NMD, Depelsenaire ACI, Crichton ML, Kuo P, Phipps S, Kendall MAF.

J Control Release. 2019 May 28;302:190-200. doi: 10.1016/j.jconrel.2019.03.027. Epub 2019 Mar 30.


Personalised anti-inflammatory therapy for bronchiectasis and cystic fibrosis: selecting patients for controlled trials of neutrophil elastase inhibition.

Keir HR, Fong CJ, Crichton ML, Barth P, Chevalier E, Brady G, Kennedy G, Zimmermann J, Bruijnzeel PLB, Dicker AJ, Chalmers JD.

ERJ Open Res. 2019 Mar 25;5(1). pii: 00252-2018. doi: 10.1183/23120541.00252-2018. eCollection 2019 Feb.


A systematic review of pharmacotherapeutic clinical trial end-points for bronchiectasis in adults.

Crichton ML, Aliberti S, Chalmers JD.

Eur Respir Rev. 2019 Mar 14;28(151). pii: 180108. doi: 10.1183/16000617.0108-2018. Print 2019 Mar 31.


Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays.

Wei JCJ, Haridass IN, Crichton ML, Mohammed YH, Meliga SC, Sanchez WY, Grice JE, Benson HAE, Roberts MS, Kendall MAF.

Sci Rep. 2018 Dec 10;8(1):17759. doi: 10.1038/s41598-018-36009-8.


Postmortem tissue distribution of morphine and its metabolites in a series of heroin-related deaths.

Maskell PD, Wilson NE, Seetohul LN, Crichton ML, Beer LJ, Drummond G, De Paoli G.

Drug Test Anal. 2019 Feb;11(2):292-304. doi: 10.1002/dta.2492. Epub 2018 Oct 18.


Allometric scaling of skin thickness, elasticity, viscoelasticity to mass for micro-medical device translation: from mice, rats, rabbits, pigs to humans.

Wei JCJ, Edwards GA, Martin DJ, Huang H, Crichton ML, Kendall MAF.

Sci Rep. 2017 Nov 21;7(1):15885. doi: 10.1038/s41598-017-15830-7.


Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD.

Dicker AJ, Crichton ML, Cassidy AJ, Brady G, Hapca A, Tavendale R, Einarsson GG, Furrie E, Elborn JS, Schembri S, Marshall SE, Palmer CNA, Chalmers JD.

Thorax. 2018 Jun;73(6):510-518. doi: 10.1136/thoraxjnl-2016-209931. Epub 2017 Nov 3.


Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease.

Dicker AJ, Crichton ML, Pumphrey EG, Cassidy AJ, Suarez-Cuartin G, Sibila O, Furrie E, Fong CJ, Ibrahim W, Brady G, Einarsson GG, Elborn JS, Schembri S, Marshall SE, Palmer CNA, Chalmers JD.

J Allergy Clin Immunol. 2018 Jan;141(1):117-127. doi: 10.1016/j.jaci.2017.04.022. Epub 2017 May 13.


The hyperelastic and failure behaviors of skin in relation to the dynamic application of microscopic penetrators in a murine model.

Meliga SC, Coffey JW, Crichton ML, Flaim C, Veidt M, Kendall MAF.

Acta Biomater. 2017 Jan 15;48:341-356. doi: 10.1016/j.actbio.2016.10.021. Epub 2016 Oct 13.


Corrigendum: The changing shape of vaccination: improving immune responses through geometrical variations of a microdevice for immunization.

Crichton ML, Muller DA, Depelsenaire AC, Pearson FE, Wei J, Coffey J, Zhang J, Fernando GJ, Kendall MA.

Sci Rep. 2016 Jul 4;6:28722. doi: 10.1038/srep28722. No abstract available.


The changing shape of vaccination: improving immune responses through geometrical variations of a microdevice for immunization.

Crichton ML, Muller DA, Depelsenaire ACI, Pearson FE, Wei J, Coffey J, Zhang J, Fernando GJP, Kendall MAF.

Sci Rep. 2016 Jun 2;6:27217. doi: 10.1038/srep27217. Erratum in: Sci Rep. 2016 Jul 04;6:28722.


Characterising the material properties at the interface between skin and a skin vaccination microprojection device.

Crichton ML, Archer-Jones C, Meliga S, Edwards G, Martin D, Huang H, Kendall MA.

Acta Biomater. 2016 May;36:186-94. doi: 10.1016/j.actbio.2016.02.039. Epub 2016 Mar 5.


Inactivated poliovirus type 2 vaccine delivered to rat skin via high density microprojection array elicits potent neutralising antibody responses.

Muller DA, Pearson FE, Fernando GJ, Agyei-Yeboah C, Owens NS, Corrie SR, Crichton ML, Wei JC, Weldon WC, Oberste MS, Young PR, Kendall MA.

Sci Rep. 2016 Feb 25;6:22094. doi: 10.1038/srep22094.


Formulations for microprojection/microneedle vaccine delivery: Structure, strength and release profiles.

Raphael AP, Crichton ML, Falconer RJ, Meliga S, Chen X, Fernando GJ, Huang H, Kendall MA.

J Control Release. 2016 Mar 10;225:40-52. doi: 10.1016/j.jconrel.2016.01.027. Epub 2016 Jan 19.


Analysis of phenazepam and 3-hydroxyphenazepam in post-mortem fluids and tissues.

Crichton ML, Shenton CF, Drummond G, Beer LJ, Seetohul LN, Maskell PD.

Drug Test Anal. 2015 Oct;7(10):926-36. doi: 10.1002/dta.1790. Epub 2015 Apr 5.


Microprojection arrays to immunise at mucosal surfaces.

McNeilly CL, Crichton ML, Primiero CA, Frazer IH, Roberts MS, Kendall MA.

J Control Release. 2014 Dec 28;196:252-60. doi: 10.1016/j.jconrel.2014.09.028. Epub 2014 Oct 5.


Dry-coated live viral vector vaccines delivered by nanopatch microprojections retain long-term thermostability and induce transgene-specific T cell responses in mice.

Pearson FE, McNeilly CL, Crichton ML, Primiero CA, Yukiko SR, Fernando GJ, Chen X, Gilbert SC, Hill AV, Kendall MA.

PLoS One. 2013 Jul 9;8(7):e67888. doi: 10.1371/journal.pone.0067888. Print 2013.


Elastic modulus and viscoelastic properties of full thickness skin characterised at micro scales.

Crichton ML, Chen X, Huang H, Kendall MA.

Biomaterials. 2013 Mar;34(8):2087-97. doi: 10.1016/j.biomaterials.2012.11.035. Epub 2012 Dec 20.


The viscoelastic, hyperelastic and scale dependent behaviour of freshly excised individual skin layers.

Crichton ML, Donose BC, Chen X, Raphael AP, Huang H, Kendall MA.

Biomaterials. 2011 Jul;32(20):4670-81. doi: 10.1016/j.biomaterials.2011.03.012. Epub 2011 Mar 31.


Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization.

Chen X, Fernando GJ, Crichton ML, Flaim C, Yukiko SR, Fairmaid EJ, Corbett HJ, Primiero CA, Ansaldo AB, Frazer IH, Brown LE, Kendall MA.

J Control Release. 2011 Jun 30;152(3):349-55. doi: 10.1016/j.jconrel.2011.02.026. Epub 2011 Mar 1.


Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays.

Chen X, Kask AS, Crichton ML, McNeilly C, Yukiko S, Dong L, Marshak JO, Jarrahian C, Fernando GJ, Chen D, Koelle DM, Kendall MA.

J Control Release. 2010 Dec 20;148(3):327-33. doi: 10.1016/j.jconrel.2010.09.001. Epub 2010 Sep 17.


Surface-modified microprojection arrays for intradermal biomarker capture, with low non-specific protein binding.

Corrie SR, Fernando GJ, Crichton ML, Brunck ME, Anderson CD, Kendall MA.

Lab Chip. 2010 Oct 21;10(20):2655-8. doi: 10.1039/c0lc00068j. Epub 2010 Aug 31.


Nanopatch-targeted skin vaccination against West Nile Virus and Chikungunya virus in mice.

Prow TW, Chen X, Prow NA, Fernando GJ, Tan CS, Raphael AP, Chang D, Ruutu MP, Jenkins DW, Pyke A, Crichton ML, Raphaelli K, Goh LY, Frazer IH, Roberts MS, Gardner J, Khromykh AA, Suhrbier A, Hall RA, Kendall MA.

Small. 2010 Aug 16;6(16):1776-84. doi: 10.1002/smll.201000331.


Targeted, needle-free vaccinations in skin using multilayered, densely-packed dissolving microprojection arrays.

Raphael AP, Prow TW, Crichton ML, Chen X, Fernando GJ, Kendall MA.

Small. 2010 Aug 16;6(16):1785-93. doi: 10.1002/smll.201000326.


Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model.

Fernando GJ, Chen X, Prow TW, Crichton ML, Fairmaid EJ, Roberts MS, Frazer IH, Brown LE, Kendall MA.

PLoS One. 2010 Apr 21;5(4):e10266. doi: 10.1371/journal.pone.0010266.


The effect of strain rate on the precision of penetration of short densely-packed microprojection array patches coated with vaccine.

Crichton ML, Ansaldo A, Chen X, Prow TW, Fernando GJ, Kendall MA.

Biomaterials. 2010 Jun;31(16):4562-72. doi: 10.1016/j.biomaterials.2010.02.022. Epub 2010 Mar 11.


Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin.

Chen X, Prow TW, Crichton ML, Jenkins DW, Roberts MS, Frazer IH, Fernando GJ, Kendall MA.

J Control Release. 2009 Nov 3;139(3):212-20. doi: 10.1016/j.jconrel.2009.06.029. Epub 2009 Jul 3.


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