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Items: 1 to 50 of 138

1.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

2.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Review. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

3.

The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells.

Lorig-Roach N, Hamkins-Indik F, Johnson TA, Tenney K, Valeriote FA, Crews P.

Tetrahedron. 2018 Jan 11;74(2):217-223. doi: 10.1016/j.tet.2017.11.029. Epub 2017 Nov 14.

4.

Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A.

Tietjen I, Williams DE, Read S, Kuang XT, Mwimanzi P, Wilhelm E, Markle T, Kinloch NN, Naphen CN, Tenney K, Mesplède T, Wainberg MA, Crews P, Bell B, Andersen RJ, Brumme ZL, Brockman MA.

Antiviral Res. 2018 Apr;152:94-103. doi: 10.1016/j.antiviral.2018.02.017. Epub 2018 Feb 22.

PMID:
29476895
5.

Investigation of the Physical and Bioactive Properties of Bromo- and Iodo-Containing Sponge-Derived Compounds Possessing an Oxyphenylethanamine Core.

McCauley EP, Lam H, Lorig-Roach N, Luu J, Lloyd C, Tenney K, Pietraszkiewicz H, Diaz C, Valeriote FA, Auerbuch V, Crews P.

J Nat Prod. 2017 Dec 22;80(12):3255-3266. doi: 10.1021/acs.jnatprod.7b00694. Epub 2017 Nov 16.

PMID:
29144750
6.

Bioactive Secondary Metabolites from the Marine Sponge Genus Agelas.

Zhang H, Dong M, Chen J, Wang H, Tenney K, Crews P.

Mar Drugs. 2017 Nov 8;15(11). pii: E351. doi: 10.3390/md15110351. Review.

7.

Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids.

Fraley AE, Garcia-Borràs M, Tripathi A, Khare D, Mercado-Marin EV, Tran H, Dan Q, Webb GP, Watts KR, Crews P, Sarpong R, Williams RM, Smith JL, Houk KN, Sherman DH.

J Am Chem Soc. 2017 Aug 30;139(34):12060-12068. doi: 10.1021/jacs.7b06773. Epub 2017 Aug 21.

8.

Evaluating Nitrogen-Containing Biosynthetic Products Produced by Saltwater Culturing of Several California Littoral Zone Gram-Negative Bacteria.

Lorig-Roach N, Still PC, Coppage D, Compton JE, Crews MS, Navarro G, Tenney K, Crews P.

J Nat Prod. 2017 Aug 25;80(8):2304-2310. doi: 10.1021/acs.jnatprod.7b00302. Epub 2017 Aug 4.

9.

Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues.

Lin S, McCauley EP, Lorig-Roach N, Tenney K, Naphen CN, Yang AM, Johnson TA, Hernadez T, Rattan R, Valeriote FA, Crews P.

Mar Drugs. 2017 Mar 29;15(4). pii: E98. doi: 10.3390/md15040098.

10.

The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects.

White KN, Tenney K, Crews P.

J Nat Prod. 2017 Mar 24;80(3):740-755. doi: 10.1021/acs.jnatprod.6b00970. Epub 2017 Feb 10. Review.

11.

Secondary Metabolites from the Marine Sponge Genus Phyllospongia.

Zhang H, Dong M, Wang H, Crews P.

Mar Drugs. 2017 Jan 6;15(1). pii: E12. doi: 10.3390/md15010012. Review.

12.

Cytotoxic Phyllactone Analogs from the Marine Sponge Phyllospongia papyrecea.

Zhang H, Crews P, Tenney K, Valeriote FA.

Med Chem. 2017;13(3):295-300. doi: 10.2174/1573406412666161007150828.

13.

Identification of the First Marine-Derived Opioid Receptor "Balanced" Agonist with a Signaling Profile That Resembles the Endorphins.

Johnson TA, Milan-Lobo L, Che T, Ferwerda M, Lambu E, McIntosh NL, Li F, He L, Lorig-Roach N, Crews P, Whistler JL.

ACS Chem Neurosci. 2017 Mar 15;8(3):473-485. doi: 10.1021/acschemneuro.6b00167. Epub 2016 Nov 22.

14.

The Bioactive Secondary Metabolites from Talaromyces species.

Zhai MM, Li J, Jiang CX, Shi YP, Di DL, Crews P, Wu QX.

Nat Prod Bioprospect. 2016 Feb;6(1):1-24. doi: 10.1007/s13659-015-0081-3. Epub 2016 Jan 8.

15.

Talaromycolides A-C, Novel Phenyl-Substituted Phthalides Isolated from the Green Chinese Onion-Derived Fungus Talaromyces pinophilus AF-02.

Zhai MM, Niu HT, Li J, Xiao H, Shi YP, Di DL, Crews P, Wu QX.

J Agric Food Chem. 2015 Nov 4;63(43):9558-64. doi: 10.1021/acs.jafc.5b04296. Epub 2015 Oct 23.

PMID:
26466717
16.

A new 3-alkylpyridine alkaloid from the marine sponge Haliclona sp. and its cytotoxic activity.

Zhang H, Loveridge ST, Tenney K, Crews P.

Nat Prod Res. 2016 Jun;30(11):1262-5. doi: 10.1080/14786419.2015.1054826. Epub 2015 Jul 13.

17.

Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products.

Ahlbach CL, Lexa KW, Bockus AT, Chen V, Crews P, Jacobson MP, Lokey RS.

Future Med Chem. 2015;7(16):2121-30. doi: 10.4155/fmc.15.78. Epub 2015 Jun 12.

18.

Biosynthetic products from a nearshore-derived gram-negative bacterium enable reassessment of the kailuin depsipeptides.

Theodore CM, Lorig-Roach N, Still PC, Johnson TA, Drašković M, Schwochert JA, Naphen CN, Crews MS, Barker SA, Valeriote FA, Lokey RS, Crews P.

J Nat Prod. 2015 Mar 27;78(3):441-52. doi: 10.1021/np500840n. Epub 2015 Feb 20.

19.

Pyrone derivatives from the endophytic fungus Alternaria tenuissima SP-07 of Chinese herbal medicine Salvia przewalskii.

Wang XZ, Luo XH, Xiao J, Zhai MM, Yuan Y, Zhu Y, Crews P, Yuan CS, Wu QX.

Fitoterapia. 2014 Dec;99:184-90. doi: 10.1016/j.fitote.2014.09.017. Epub 2014 Oct 2.

PMID:
25284429
20.

In situ natural product discovery via an artificial marine sponge.

La Clair JJ, Loveridge ST, Tenney K, O'Neil-Johnson M, Chapman E, Crews P.

PLoS One. 2014 Jul 8;9(7):e100474. doi: 10.1371/journal.pone.0100474. eCollection 2014.

21.

Scrutinizing the scaffolds of marine biosynthetics from different source organisms: Gram-negative cultured bacterial products enter center stage.

Still PC, Johnson TA, Theodore CM, Loveridge ST, Crews P.

J Nat Prod. 2014 Mar 28;77(3):690-702. doi: 10.1021/np500041x. Epub 2014 Feb 26. Review.

22.

Study of marine natural products including resorcyclic acid lactones from Humicola fuscoatra that reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells.

Mejia EJ, Loveridge ST, Stepan G, Tsai A, Jones GS, Barnes T, White KN, Drašković M, Tenney K, Tsiang M, Geleziunas R, Cihlar T, Pagratis N, Tian Y, Yu H, Crews P.

J Nat Prod. 2014 Mar 28;77(3):618-24. doi: 10.1021/np400889x. Epub 2014 Feb 4.

23.

Thelepamide: an unprecedented ketide-amino acid from Thelepus crispus, a marine annelid worm.

Rodríguez J, Nieto RM, Blanco M, Valeriote FA, Jiménez C, Crews P.

Org Lett. 2014 Jan 17;16(2):464-7. doi: 10.1021/ol403350e. Epub 2013 Dec 20.

24.

Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.

Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO.

J Med Chem. 2013 May 23;56(10):3996-4016. doi: 10.1021/jm400227z. Epub 2013 May 1.

25.

Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases.

Rohena CC, Peng J, Johnson TA, Crews P, Mooberry SL.

Biochem Pharmacol. 2013 Apr 15;85(8):1104-14. doi: 10.1016/j.bcp.2013.01.030. Epub 2013 Feb 8.

26.

Structures and cytotoxic evaluation of new and known acyclic Ene-Ynes from an American Samoa Petrosia sp. Sponge.

Mejia EJ, Magranet LB, De Voogd NJ, Tendyke K, Qiu D, Shen YY, Zhou Z, Crews P.

J Nat Prod. 2013 Mar 22;76(3):425-32. doi: 10.1021/np3008446. Epub 2013 Jan 31.

27.

Discovery and development of anticancer agents from marine sponges: perspectives based on a chemistry-experimental therapeutics collaborative program.

Valeriote FA, Tenney K, Media J, Pietraszkiewicz H, Edelstein M, Johnson TA, Amagata T, Crews P.

J Exp Ther Oncol. 2012;10(2):119-34.

PMID:
23350352
28.

New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker.

Jiang HL, Luo XH, Wang XZ, Yang JL, Yao XJ, Crews P, Valeriote FA, Wu QX.

Fitoterapia. 2012 Oct;83(7):1275-80. doi: 10.1016/j.fitote.2012.06.005. Epub 2012 Jun 23.

PMID:
22735600
29.

Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries.

Johnson TA, Sohn J, Vaske YM, White KN, Cohen TL, Vervoort HC, Tenney K, Valeriote FA, Bjeldanes LF, Crews P.

Bioorg Med Chem. 2012 Jul 15;20(14):4348-55. doi: 10.1016/j.bmc.2012.05.043. Epub 2012 May 24.

30.

The biosynthetic products of Chinese insect medicine, Aspongopus chinensis.

Luo XH, Wang XZ, Jiang HL, Yang JL, Crews P, Valeriote FA, Wu QX.

Fitoterapia. 2012 Jun;83(4):754-8. doi: 10.1016/j.fitote.2012.03.002. Epub 2012 Mar 11.

31.

Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola.

Wu QX, Jin XJ, Draskovic M, Crews MS, Tenney K, Valeriote FA, Yao XJ, Crews P.

Phytochem Lett. 2012 Mar 1;5(1):114-117.

32.

Natural product libraries to accelerate the high-throughput discovery of therapeutic leads.

Johnson TA, Sohn J, Inman WD, Estee SA, Loveridge ST, Vervoort HC, Tenney K, Liu J, Ang KK, Ratnam J, Bray WM, Gassner NC, Shen YY, Lokey RS, McKerrow JH, Boundy-Mills K, Nukanto A, Kanti A, Julistiono H, Kardono LB, Bjeldanes LF, Crews P.

J Nat Prod. 2011 Dec 27;74(12):2545-55. doi: 10.1021/np200673b. Epub 2011 Nov 30.

33.

Harnessing the biosynthetic capacity of marine-derived organisms.

Carter GT, Crews P.

Bioorg Med Chem. 2011 Nov 15;19(22):6556. doi: 10.1016/j.bmc.2011.10.050. Epub 2011 Oct 20. No abstract available.

PMID:
22036608
34.

Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants.

Radjasa OK, Vaske YM, Navarro G, Vervoort HC, Tenney K, Linington RG, Crews P.

Bioorg Med Chem. 2011 Nov 15;19(22):6658-74. doi: 10.1016/j.bmc.2011.07.017. Epub 2011 Jul 26. Review.

35.

Utilizing DART mass spectrometry to pinpoint halogenated metabolites from a marine invertebrate-derived fungus.

Watts KR, Loveridge ST, Tenney K, Media J, Valeriote FA, Crews P.

J Org Chem. 2011 Aug 5;76(15):6201-8. doi: 10.1021/jo2009593. Epub 2011 Jun 29.

36.

Biostructural features of additional jasplakinolide (jaspamide) analogues.

Watts KR, Morinaka BI, Amagata T, Robinson SJ, Tenney K, Bray WM, Gassner NC, Lokey RS, Media J, Valeriote FA, Crews P.

J Nat Prod. 2011 Mar 25;74(3):341-51. doi: 10.1021/np100721g. Epub 2011 Jan 11.

37.
38.

Histone deacetylase inhibitors as a tool to up-regulate new fungal biosynthetic products: isolation of EGM-556, a cyclodepsipeptide, from Microascus sp.

Vervoort HC, Drašković M, Crews P.

Org Lett. 2011 Feb 4;13(3):410-3. doi: 10.1021/ol1027199. Epub 2010 Dec 21.

39.

Linking chemical and microbial diversity in marine sponges: possible role for poribacteria as producers of methyl-branched fatty acids.

Hochmuth T, Niederkrüger H, Gernert C, Siegl A, Taudien S, Platzer M, Crews P, Hentschel U, Piel J.

Chembiochem. 2010 Dec 10;11(18):2572-8. doi: 10.1002/cbic.201000510.

PMID:
21077090
40.

The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules.

Watts KR, Tenney K, Crews P.

Curr Opin Biotechnol. 2010 Dec;21(6):808-18. doi: 10.1016/j.copbio.2010.09.015. Epub 2010 Oct 16. Review.

41.

Azonazine, a novel dipeptide from a Hawaiian marine sediment-derived fungus, Aspergillus insulicola.

Wu QX, Crews MS, Draskovic M, Sohn J, Johnson TA, Tenney K, Valeriote FA, Yao XJ, Bjeldanes LF, Crews P.

Org Lett. 2010 Oct 15;12(20):4458-61. doi: 10.1021/ol101396n.

42.

The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.

Morgan JB, Mahdi F, Liu Y, Coothankandaswamy V, Jekabsons MB, Johnson TA, Sashidhara KV, Crews P, Nagle DG, Zhou YD.

Bioorg Med Chem. 2010 Aug 15;18(16):5988-94. doi: 10.1016/j.bmc.2010.06.072. Epub 2010 Jun 25.

43.

Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.

Watts KR, Ratnam J, Ang KH, Tenney K, Compton JE, McKerrow J, Crews P.

Bioorg Med Chem. 2010 Apr 1;18(7):2566-74. doi: 10.1016/j.bmc.2010.02.034. Epub 2010 Mar 1.

44.

New structures and bioactivity properties of jasplakinolide (jaspamide) analogues from marine sponges.

Robinson SJ, Morinaka BI, Amagata T, Tenney K, Bray WM, Gassner NC, Lokey RS, Crews P.

J Med Chem. 2010 Feb 25;53(4):1651-61. doi: 10.1021/jm9013554.

45.

Additional insights on the bastadins: isolation of analogues from the sponge Ianthella cf. reticulata and exploration of the oxime configurations.

Calcul L, Inman WD, Morris AA, Tenney K, Ratnam J, McKerrow JH, Valeriote FA, Crews P.

J Nat Prod. 2010 Mar 26;73(3):365-72. doi: 10.1021/np9005986.

46.

Development and validation of a rapid method for the detection of latrunculol A in plasma.

Shaw J, Valeriote FA, Media J, Johnson TA, Amagata T, Tenney K, Crews P.

Anal Bioanal Chem. 2010 Mar;396(5):1741-4. doi: 10.1007/s00216-009-3385-5. Epub 2009 Dec 31.

47.

Assessing pressurized liquid extraction for the high-throughput extraction of marine-sponge-derived natural products.

Johnson TA, Morgan MV, Aratow NA, Estee SA, Sashidhara KV, Loveridge ST, Segraves NL, Crews P.

J Nat Prod. 2010 Mar 26;73(3):359-64. doi: 10.1021/np900565a.

48.

A beta-carboline alkaloid from the Papua New Guinea marine sponge hyrtios reticulatus.

Inman WD, Bray WM, Gassner NC, Lokey RS, Tenney K, Shen YY, Tendyke K, Suh T, Crews P.

J Nat Prod. 2010 Feb 26;73(2):255-7. doi: 10.1021/np9005426.

49.

Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes.

Robinson SJ, Hoobler EK, Riener M, Loveridge ST, Tenney K, Valeriote FA, Holman TR, Crews P.

J Nat Prod. 2009 Oct;72(10):1857-63. doi: 10.1021/np900465e.

50.

Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting.

Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J.

Nat Chem Biol. 2009 Jul;5(7):494-501. doi: 10.1038/nchembio.176.

PMID:
19448639

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