Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 142

1.

Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells.

Djehal A, Krayem M, Najem A, Hammoud H, Cresteil T, Nebigil CG, Wang D, Yu P, Bentouhami E, Ghanem GE, Désaubry L.

Eur J Med Chem. 2018 Jul 15;155:880-888. doi: 10.1016/j.ejmech.2018.06.052. Epub 2018 Jun 23.

PMID:
29960207
2.

First-in-Class Combination Therapy of a Copper(II) Metallo-Phosphorus Dendrimer with Cytotoxic Agents.

Mignani S, El Brahmi N, Cresteil T, Majoral JP.

Oncology. 2018;94(5):324-328. doi: 10.1159/000486680. Epub 2018 Mar 13.

PMID:
29533961
3.

Original Multivalent Gold(III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents.

Mignani SM, El Brahmi N, El Kazzouli S, Laurent R, Ladeira S, Caminade AM, Pedziwiatr-Werbicka E, Szewczyk EM, Bryszewska M, Bousmina MM, Cresteil T, Majoral JP.

Mol Pharm. 2017 Nov 6;14(11):4087-4097. doi: 10.1021/acs.molpharmaceut.7b00771. Epub 2017 Oct 9.

PMID:
28960997
4.

Anticancer copper(II) phosphorus dendrimers are potent proapoptotic Bax activators.

Mignani S, El Brahmi N, Eloy L, Poupon J, Nicolas V, Steinmetz A, El Kazzouli S, Bousmina MM, Blanchard-Desce M, Caminade AM, Majoral JP, Cresteil T.

Eur J Med Chem. 2017 May 26;132:142-156. doi: 10.1016/j.ejmech.2017.03.035. Epub 2017 Mar 21.

PMID:
28350998
5.

Benzylphenylpyrrolizinones with Anti-amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment.

Jourdan JP, Since M, El Kihel L, Lecoutey C, Corvaisier S, Legay R, Sopková-de Oliveira Santos J, Cresteil T, Malzert-Fréon A, Rochais C, Dallemagne P.

ChemMedChem. 2017 Jun 21;12(12):913-916. doi: 10.1002/cmdc.201700102. Epub 2017 Apr 12.

PMID:
28342294
6.

A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action.

Mignani S, El Brahmi N, El Kazzouli S, Eloy L, Courilleau D, Caron J, Bousmina MM, Caminade AM, Cresteil T, Majoral JP.

Eur J Med Chem. 2016 Oct 21;122:656-673. doi: 10.1016/j.ejmech.2016.05.063. Epub 2016 Jun 11.

PMID:
27448922
7.

Linking of Antitumor trans NHC-Pt(II) Complexes to G-Quadruplex DNA Ligand for Telomeric Targeting.

Betzer JF, Nuter F, Chtchigrovsky M, Hamon F, Kellermann G, Ali S, Calméjane MA, Roque S, Poupon J, Cresteil T, Teulade-Fichou MP, Marinetti A, Bombard S.

Bioconjug Chem. 2016 Jun 15;27(6):1456-70. doi: 10.1021/acs.bioconjchem.6b00079. Epub 2016 May 17.

PMID:
27115175
8.

Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment.

Jourdan JP, Since M, El Kihel L, Lecoutey C, Corvaisier S, Legay R, Sopkova-de Oliveira Santos J, Cresteil T, Malzert-Fréon A, Rochais C, Dallemagne P.

Eur J Med Chem. 2016 May 23;114:365-79. doi: 10.1016/j.ejmech.2016.03.023. Epub 2016 Mar 12.

PMID:
27046230
9.

Antidiabetic potential of two medicinal plants used in Gabonese folk medicine.

Agnaniet H, Mbot EJ, Keita O, Fehrentz JA, Ankli A, Gallud A, Garcia M, Gary-Bobo M, Lebibi J, Cresteil T, Menut C.

BMC Complement Altern Med. 2016 Feb 22;16:71. doi: 10.1186/s12906-016-1052-x.

10.

Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives.

Fontaine F, Héquet A, Voisin-Chiret AS, Bouillon A, Lesnard A, Cresteil T, Jolivalt C, Rault S.

Eur J Med Chem. 2015 May 5;95:185-98. doi: 10.1016/j.ejmech.2015.02.056. Epub 2015 Mar 2.

PMID:
25817769
11.

Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with ethacrynic acid motifs.

El Brahmi N, Mignani SM, Caron J, El Kazzouli S, Bousmina MM, Caminade AM, Cresteil T, Majoral JP.

Nanoscale. 2015 Mar 7;7(9):3915-22. doi: 10.1039/c4nr05983b.

PMID:
25503793
12.

Synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents.

Le Floch C, Le Gall E, Sengmany S, Renevret P, Léonel E, Martens T, Cresteil T.

Eur J Med Chem. 2015 Jan 7;89:654-70. doi: 10.1016/j.ejmech.2014.10.074. Epub 2014 Oct 28.

PMID:
25462273
13.

Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.

Lecoutey C, Hedou D, Freret T, Giannoni P, Gaven F, Since M, Bouet V, Ballandonne C, Corvaisier S, Malzert Fréon A, Mignani S, Cresteil T, Boulouard M, Claeysen S, Rochais C, Dallemagne P.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3825-30. doi: 10.1073/pnas.1410315111. Epub 2014 Aug 25.

14.

α-Glucosidase inhibitory activity of marine sponges collected in Mauritius waters.

Ramanjooloo A, Cresteil T, Lebrasse C, Beedessee G, Oogarah P, van Soest RW, Marie DE.

Nat Prod Res. 2015;29(4):383-7. doi: 10.1080/14786419.2014.945173. Epub 2014 Aug 13.

PMID:
25116959
15.

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach.

Elkaim J, Lamblin M, Laguerre M, Rosenbaum J, Lestienne P, Eloy L, Cresteil T, Felpin FX, Dessolin J.

Bioorg Med Chem Lett. 2014 Jun 1;24(11):2512-6. doi: 10.1016/j.bmcl.2014.04.003. Epub 2014 Apr 13.

PMID:
24767849
16.

Evaluation of hexane and ethyl acetate extracts of the sponge Jaspis diastra collected from Mauritius Waters on HeLa cells.

Beedessee G, Ramanjooloo A, Tiscornia I, Cresteil T, Raghothama S, Arya D, Rao S, Gowd KH, Bollati-Fogolin M, Marie DE.

J Pharm Pharmacol. 2014 Sep;66(9):1317-27. doi: 10.1111/jphp.12256. Epub 2014 Apr 24.

PMID:
24758528
17.

First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump.

Fontaine F, Hequet A, Voisin-Chiret AS, Bouillon A, Lesnard A, Cresteil T, Jolivalt C, Rault S.

J Med Chem. 2014 Mar 27;57(6):2536-48. doi: 10.1021/jm401808n. Epub 2014 Feb 19.

PMID:
24499135
18.

A concise formation of N-substituted 3,4-diarylpyrroles--synthesis and cytotoxic activity.

Egorov M, Delpech B, Aubert G, Cresteil T, Garcia-Alvarez MC, Collin P, Marazano C.

Org Biomol Chem. 2014 Mar 7;12(9):1518-24. doi: 10.1039/c3ob42309c.

PMID:
24448828
19.

Synthesis and evaluation of cytotoxic activities of new guanidines derived from carbazoles.

Caruso A, Sinicropi MS, Lancelot JC, El-Kashef H, Saturnino C, Aubert G, Ballandonne C, Lesnard A, Cresteil T, Dallemagne P, Rault S.

Bioorg Med Chem Lett. 2014 Jan 15;24(2):467-72. doi: 10.1016/j.bmcl.2013.12.047. Epub 2013 Dec 17.

PMID:
24374274
20.

Synthesis and evaluation of 3-deoxy and 3-deoxy-3-fluoro derivatives of gluco- and manno-configured tetrahydropyridoimidazole glycosidase inhibitors.

Ouairy C, Cresteil T, Delpech B, Crich D.

Carbohydr Res. 2013 Aug 9;377:35-43. doi: 10.1016/j.carres.2013.05.011. Epub 2013 May 21.

PMID:
23792222
21.

The cytosolic chaperonin CCT/TRiC and cancer cell proliferation.

Boudiaf-Benmammar C, Cresteil T, Melki R.

PLoS One. 2013 Apr 16;8(4):e60895. doi: 10.1371/journal.pone.0060895. Print 2013.

22.

Ethyl acetate extract of the Mauritian sponge Jaspis sp. induces cell arrest in human promyelocytic leukemia cells.

Beedessee G, Ramanjooloo A, Aubert G, Eloy L, Arya D, van Soest RW, Cresteil T, Marie DE.

Environ Toxicol Pharmacol. 2013 Jul;36(1):58-65. doi: 10.1016/j.etap.2013.03.002. Epub 2013 Mar 15.

PMID:
23598257
23.

Antitumor trans-N-heterocyclic carbene-amine-Pt(II) complexes: synthesis of dinuclear species and exploratory investigations of DNA binding and cytotoxicity mechanisms.

Chtchigrovsky M, Eloy L, Jullien H, Saker L, Ségal-Bendirdjian E, Poupon J, Bombard S, Cresteil T, Retailleau P, Marinetti A.

J Med Chem. 2013 Mar 14;56(5):2074-86. doi: 10.1021/jm301780s. Epub 2013 Feb 20.

PMID:
23421599
24.

Original multivalent copper(II)-conjugated phosphorus dendrimers and corresponding mononuclear copper(II) complexes with antitumoral activities.

El Brahmi N, El Kazzouli S, Mignani SM, Essassi el M, Aubert G, Laurent R, Caminade AM, Bousmina MM, Cresteil T, Majoral JP.

Mol Pharm. 2013 Apr 1;10(4):1459-64. doi: 10.1021/mp4000184. Epub 2013 Mar 7.

PMID:
23410260
25.

MR22388, a novel anti-cancer agent with a strong FLT-3 ITD kinase affinity.

Rochais C, Cresteil T, Perri V, Jouanne M, Lesnard A, Rault S, Dallemagne P.

Cancer Lett. 2013 Apr 30;331(1):92-8. doi: 10.1016/j.canlet.2012.12.017. Epub 2012 Dec 23.

PMID:
23268332
26.

N-O bond as a glycosidic-bond surrogate: synthetic studies toward polyhydroxylated N-alkoxypiperidines.

Malik G, Ferry A, Guinchard X, Cresteil T, Crich D.

Chemistry. 2013 Feb 4;19(6):2168-79. doi: 10.1002/chem.201202374. Epub 2012 Dec 19.

PMID:
23255330
27.

Flavaglines as potent anticancer and cytoprotective agents.

Ribeiro N, Thuaud F, Bernard Y, Gaiddon C, Cresteil T, Hild A, Hirsch EC, Michel PP, Nebigil CG, Désaubry L.

J Med Chem. 2012 Nov 26;55(22):10064-73. doi: 10.1021/jm301201z. Epub 2012 Oct 23.

PMID:
23072299
28.

New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888.

Mani L, Jullian V, Mourkazel B, Valentin A, Dubois J, Cresteil T, Folcher E, Hooper JN, Erpenbeck D, Aalbersberg W, Debitus C.

Chem Biodivers. 2012 Aug;9(8):1436-51. doi: 10.1002/cbdv.201100309.

PMID:
22899605
29.

Cytotoxic activities of hexane, ethyl acetate and butanol extracts of marine sponges from Mauritian Waters on human cancer cell lines.

Beedessee G, Ramanjooloo A, Aubert G, Eloy L, Surnam-Boodhun R, Soest RWMV, Cresteil T, Marie DEP.

Environ Toxicol Pharmacol. 2012 Sep;34(2):397-408. doi: 10.1016/j.etap.2012.05.013. Epub 2012 Jun 9.

PMID:
22743579
30.

Synthesis of novel 7-oxo and 7-hydroxy trifluoroallocolchicinoids with cytotoxic effect.

Chosson E, Santoro F, Rochais C, Santos JS, Legay R, Thoret S, Cresteil T, Sinicropi MS, Besson T, Dallemagne P.

Bioorg Med Chem. 2012 Apr 15;20(8):2614-23. doi: 10.1016/j.bmc.2012.02.043. Epub 2012 Mar 3.

PMID:
22429510
31.

Anticancer activity of silver-N-heterocyclic carbene complexes: caspase-independent induction of apoptosis via mitochondrial apoptosis-inducing factor (AIF).

Eloy L, Jarrousse AS, Teyssot ML, Gautier A, Morel L, Jolivalt C, Cresteil T, Roland S.

ChemMedChem. 2012 May;7(5):805-14. doi: 10.1002/cmdc.201200055. Epub 2012 Mar 1.

PMID:
22383263
32.

Pipestelides A-C: cyclodepsipeptides from the Pacific marine sponge Pipestela candelabra.

Sorres J, Martin MT, Petek S, Levaique H, Cresteil T, Ramos S, Thoison O, Debitus C, Al-Mourabit A.

J Nat Prod. 2012 Apr 27;75(4):759-63. doi: 10.1021/np200714m. Epub 2012 Feb 24.

PMID:
22364566
33.

Synthesis and biological investigation of the β-thiolactone and β-lactam analogs of tetrahydrolipstatin.

Aubry S, Aubert G, Cresteil T, Crich D.

Org Biomol Chem. 2012 Apr 7;10(13):2629-32. doi: 10.1039/c2ob06976h. Epub 2012 Feb 21.

PMID:
22354549
34.

Synthesis and biological evaluation of acridine derivatives as antimalarial agents.

Yu XM, Ramiandrasoa F, Guetzoyan L, Pradines B, Quintino E, Gadelle D, Forterre P, Cresteil T, Mahy JP, Pethe S.

ChemMedChem. 2012 Apr;7(4):587-605. doi: 10.1002/cmdc.201100554. Epub 2012 Feb 13.

PMID:
22331612
35.

Influence of the skeleton on the cytotoxicity of flavonoids.

Lewin G, Aubert G, Thoret S, Dubois J, Cresteil T.

Bioorg Med Chem. 2012 Feb 1;20(3):1231-9. doi: 10.1016/j.bmc.2011.12.038. Epub 2011 Dec 30.

PMID:
22257529
36.

In vitro inhibitory properties of ferrocene-substituted chalcones and aurones on bacterial and human cell cultures.

Tiwari KN, Monserrat JP, Hequet A, Ganem-Elbaz C, Cresteil T, Jaouen G, Vessières A, Hillard EA, Jolivalt C.

Dalton Trans. 2012 Jun 7;41(21):6451-7. doi: 10.1039/c2dt12180h. Epub 2012 Jan 12.

PMID:
22240736
37.

Synthesis and cytotoxic evaluation of novel paraconic acid analogs.

Le Floch C, Le Gall E, Léonel E, Martens T, Cresteil T.

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7054-8. doi: 10.1016/j.bmcl.2011.09.092. Epub 2011 Sep 29.

PMID:
22004720
38.

Exploring the potential of the β-thiolactones in bioorganic chemistry.

Aubry S, Sasaki K, Eloy L, Aubert G, Retailleau P, Cresteil T, Crich D.

Org Biomol Chem. 2011 Oct 21;9(20):7134-43. doi: 10.1039/c1ob05967j. Epub 2011 Sep 2.

PMID:
21892453
39.

Swinholide J, a potent cytotoxin from the marine sponge Theonella swinhoei.

De Marino S, Festa C, D'Auria MV, Cresteil T, Debitus C, Zampella A.

Mar Drugs. 2011;9(6):1133-41. doi: 10.3390/md9061133. Epub 2011 Jun 22.

40.

Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp.

Longeon A, Copp BR, Quévrain E, Roué M, Kientz B, Cresteil T, Petek S, Debitus C, Bourguet-Kondracki ML.

Mar Drugs. 2011;9(5):879-88. doi: 10.3390/md9050879. Epub 2011 May 24.

41.

Benzylidenemalononitrile compounds as activators of cell resistance to oxidative stress and modulators of multiple signaling pathways. A structure-activity relationship study.

Turpaev K, Ermolenko M, Cresteil T, Drapier JC.

Biochem Pharmacol. 2011 Sep 1;82(5):535-47. doi: 10.1016/j.bcp.2011.05.028. Epub 2011 Jun 2.

PMID:
21669191
42.

Design, synthesis and antiproliferative activities of biarylolefins based on polyhydroxylated and carbohydrate scaffolds.

Novoa A, Pellegrini-Moïse N, Bourg S, Thoret S, Dubois J, Aubert G, Cresteil T, Chapleur Y.

Eur J Med Chem. 2011 Sep;46(9):3570-80. doi: 10.1016/j.ejmech.2011.05.021. Epub 2011 May 13.

PMID:
21636180
43.

Investigation of a series of silver-N-heterocyclic carbenes as antibacterial agents: activity, synergistic effects, and cytotoxicity.

Roland S, Jolivalt C, Cresteil T, Eloy L, Bouhours P, Hequet A, Mansuy V, Vanucci C, Paris JM.

Chemistry. 2011 Feb 1;17(5):1442-6. doi: 10.1002/chem.201002812. Epub 2011 Jan 5. No abstract available.

PMID:
21268146
44.

Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.

Lewin G, Shridhar NB, Aubert G, Thoret S, Dubois J, Cresteil T.

Bioorg Med Chem. 2011 Jan 1;19(1):186-96. doi: 10.1016/j.bmc.2010.11.035. Epub 2010 Nov 20.

PMID:
21146994
45.

Novel flavaglines displaying improved cytotoxicity.

Thuaud F, Ribeiro N, Gaiddon C, Cresteil T, Désaubry L.

J Med Chem. 2011 Jan 13;54(1):411-5. doi: 10.1021/jm101318b. Epub 2010 Dec 13.

PMID:
21142180
46.

Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin.

Lewin G, Maciuk A, Thoret S, Aubert G, Dubois J, Cresteil T.

J Nat Prod. 2010 Apr 23;73(4):702-6. doi: 10.1021/np100065v.

PMID:
20356063
47.

Hydrogenative desulphurization of thienopyrrolizinones: an easy and selective access to (Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity.

Perri V, Rochais C, Sopkova-de Oliveira Santos J, Legay R, Cresteil T, Dallemagne P, Rault S.

Eur J Med Chem. 2010 Mar;45(3):1146-50. doi: 10.1016/j.ejmech.2009.12.021. Epub 2009 Dec 21.

PMID:
20053482
48.

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines.

Madonna S, Béclin C, Laras Y, Moret V, Marcowycz A, Lamoral-Theys D, Dubois J, Barthelemy-Requin M, Lenglet G, Depauw S, Cresteil T, Aubert G, Monnier V, Kiss R, David-Cordonnier MH, Kraus JL.

Eur J Med Chem. 2010 Feb;45(2):623-38. doi: 10.1016/j.ejmech.2009.11.006. Epub 2009 Nov 10.

PMID:
19931949
49.

Antimalarial acridines: synthesis, in vitro activity against P. falciparum and interaction with hematin.

Guetzoyan L, Yu XM, Ramiandrasoa F, Pethe S, Rogier C, Pradines B, Cresteil T, Perrée-Fauvet M, Mahy JP.

Bioorg Med Chem. 2009 Dec 1;17(23):8032-9. doi: 10.1016/j.bmc.2009.10.005. Epub 2009 Oct 9.

PMID:
19879150
50.

Synthesis, reactivity and biological evaluation of novel halogenated tripentones.

Perri V, Rochais C, Cresteil T, Dallemagne P, Rault S.

Bioorg Med Chem. 2009 Nov 15;17(22):7783-8. doi: 10.1016/j.bmc.2009.09.027. Epub 2009 Sep 19.

PMID:
19822434

Supplemental Content

Loading ...
Support Center