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Items: 48

1.

Perspective on the Development of a Large-Scale Clinical Data Repository for Pediatric Hearing Research.

Pennington JW, Ruth B, Miller JM, Peterson J, Xu B, Masino AJ, Krantz I, Manganella J, Gomes T, Stiles D, Kenna M, Hood LJ, Germiller J, Crenshaw EB 3rd.

Ear Hear. 2019 Aug 9. doi: 10.1097/AUD.0000000000000779. [Epub ahead of print]

PMID:
31408044
2.

Outcomes of evaluation and testing of 660 individuals with hearing loss in a pediatric genetics of hearing loss clinic.

Mehta D, Noon SE, Schwartz E, Wilkens A, Bedoukian EC, Scarano I, Crenshaw EB 3rd, Krantz ID.

Am J Med Genet A. 2016 Oct;170(10):2523-30. doi: 10.1002/ajmg.a.37855. Epub 2016 Aug 2.

PMID:
27480936
3.

Temporal bone radiology report classification using open source machine learning and natural langue processing libraries.

Masino AJ, Grundmeier RW, Pennington JW, Germiller JA, Crenshaw EB 3rd.

BMC Med Inform Decis Mak. 2016 Jun 6;16:65. doi: 10.1186/s12911-016-0306-3.

4.

Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse.

Raft S, Coate TM, Kelley MW, Crenshaw EB 3rd, Wu DK.

PLoS One. 2014 Oct 9;9(10):e109043. doi: 10.1371/journal.pone.0109043. eCollection 2014.

5.

Harvest: a web-based biomedical data discovery and reporting application development platform.

Italia MJ, Pennington JW, Ruth B, Wrazien S, Loutrel JG, Crenshaw EB 3rd, Miller J, White PS.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:82. eCollection 2013.

PMID:
24303304
6.

Harvest: an open platform for developing web-based biomedical data discovery and reporting applications.

Pennington JW, Ruth B, Italia MJ, Miller J, Wrazien S, Loutrel JG, Crenshaw EB, White PS.

J Am Med Inform Assoc. 2014 Mar-Apr;21(2):379-83. doi: 10.1136/amiajnl-2013-001825. Epub 2013 Oct 16.

7.

BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord.

Hazen VM, Andrews MG, Umans L, Crenshaw EB 3rd, Zwijsen A, Butler SJ.

Dev Biol. 2012 Jul 15;367(2):216-27. doi: 10.1016/j.ydbio.2012.05.014. Epub 2012 May 17. Erratum in: Dev Biol. 2012 Sep 15;369(2):386.

8.

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.

John A, Brylka H, Wiegreffe C, Simon R, Liu P, Jüttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S.

Development. 2012 May;139(10):1831-41. doi: 10.1242/dev.072850. Epub 2012 Apr 4.

9.

Otic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathway.

Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW.

Neuron. 2012 Jan 12;73(1):49-63. doi: 10.1016/j.neuron.2011.10.029.

10.

The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development.

Thein DC, Thalhammer JM, Hartwig AC, Crenshaw EB 3rd, Lefebvre V, Wegner M, Sock E.

J Neurochem. 2010 Oct;115(1):131-41. doi: 10.1111/j.1471-4159.2010.06910.x. Epub 2010 Aug 3.

11.

Wnt signaling is sufficient to perturb oligodendrocyte maturation.

Feigenson K, Reid M, See J, Crenshaw EB 3rd, Grinspan JB.

Mol Cell Neurosci. 2009 Nov;42(3):255-65. doi: 10.1016/j.mcn.2009.07.010. Epub 2009 Jul 18.

PMID:
19619658
12.

Otic mesenchyme expression of Cre recombinase directed by the inner ear enhancer of the Brn4/Pou3f4 gene.

Ahn KJ, Passero F Jr, Crenshaw EB 3rd.

Genesis. 2009 Mar;47(3):137-41. doi: 10.1002/dvg.20454.

PMID:
19217071
13.

Cooperative function of Tbx1 and Brn4 in the periotic mesenchyme is necessary for cochlea formation.

Braunstein EM, Crenshaw EB 3rd, Morrow BE, Adams JC.

J Assoc Res Otolaryngol. 2008 Mar;9(1):33-43. doi: 10.1007/s10162-008-0110-6. Epub 2008 Jan 30.

14.

BMP signaling mutant mice exhibit glial cell maturation defects.

See J, Mamontov P, Ahn K, Wine-Lee L, Crenshaw EB 3rd, Grinspan JB.

Mol Cell Neurosci. 2007 May;35(1):171-82. Epub 2007 Feb 23.

15.

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.

Zechner D, Müller T, Wende H, Walther I, Taketo MM, Crenshaw EB 3rd, Treier M, Birchmeier W, Birchmeier C.

Dev Biol. 2007 Mar 1;303(1):181-90. Epub 2006 Nov 6.

16.

Noncanonical Wnt signaling and neural polarity.

Montcouquiol M, Crenshaw EB 3rd, Kelley MW.

Annu Rev Neurosci. 2006;29:363-86. Review.

PMID:
16776590
17.
18.

Abnormal mesenchymal differentiation in the superior semicircular canal of brn4/pou3f4 knockout mice.

Sobol SE, Teng X, Crenshaw EB 3rd.

Arch Otolaryngol Head Neck Surg. 2005 Jan;131(1):41-5.

PMID:
15655183
19.

Mutation of the POU-domain gene Brn4/Pou3f4 affects middle-ear sound conduction in the mouse.

Samadi DS, Saunders JC, Crenshaw EB 3rd.

Hear Res. 2005 Jan;199(1-2):11-21.

PMID:
15574296
20.

Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord.

Wine-Lee L, Ahn KJ, Richardson RD, Mishina Y, Lyons KM, Crenshaw EB 3rd.

Development. 2004 Nov;131(21):5393-403. Epub 2004 Oct 6.

21.

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

Andl T, Ahn K, Kairo A, Chu EY, Wine-Lee L, Reddy ST, Croft NJ, Cebra-Thomas JA, Metzger D, Chambon P, Lyons KM, Mishina Y, Seykora JT, Crenshaw EB 3rd, Millar SE.

Development. 2004 May;131(10):2257-68. Epub 2004 Apr 21.

22.

The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity.

Heller RS, Stoffers DA, Liu A, Schedl A, Crenshaw EB 3rd, Madsen OD, Serup P.

Dev Biol. 2004 Apr 1;268(1):123-34.

23.

Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling [corrected].

Suzuki K, Bachiller D, Chen YP, Kamikawa M, Ogi H, Haraguchi R, Ogino Y, Minami Y, Mishina Y, Ahn K, Crenshaw EB 3rd, Yamada G.

Development. 2003 Dec;130(25):6209-20. Epub 2003 Nov 5. Erratum in: Development. 2003 Dec;130(26):6643.

24.

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.

Soshnikova N, Zechner D, Huelsken J, Mishina Y, Behringer RR, Taketo MM, Crenshaw EB 3rd, Birchmeier W.

Genes Dev. 2003 Aug 15;17(16):1963-8.

25.

beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system.

Zechner D, Fujita Y, Hülsken J, Müller T, Walther I, Taketo MM, Crenshaw EB 3rd, Birchmeier W, Birchmeier C.

Dev Biol. 2003 Jun 15;258(2):406-18.

26.

Bone morphogenetic protein 4 (BMP4): a regulator of capsule chondrogenesis in the developing mouse inner ear.

Liu W, Oh SH, Kang Yk Yk, Li G, Doan TM, Little M, Li L, Ahn K, Crenshaw EB 3rd, Frenz DA.

Dev Dyn. 2003 Mar;226(3):427-38.

27.

BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb.

Ahn K, Mishina Y, Hanks MC, Behringer RR, Crenshaw EB 3rd.

Development. 2001 Nov;128(22):4449-61.

28.

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).

Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB 3rd, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ.

Science. 2001 Jun 1;292(5522):1728-31.

29.

Regulatory regions from the Brn4 promoter direct LACZ expression to the developing forebrain and neural tube.

Heydemann A, Nguyen LC, Crenshaw EB 3rd.

Brain Res Dev Brain Res. 2001 May 31;128(1):83-90.

PMID:
11356266
30.

A transgenic insertional inner ear mutation on mouse chromosome 1.

Friedman RA, Adir Y, Crenshaw EB, Ryan AF, Rosenfeld MG.

Laryngoscope. 2000 Apr;110(4):489-96.

31.

The sex-linked fidget mutation abolishes Brn4/Pou3f4 gene expression in the embryonic inner ear.

Phippard D, Boyd Y, Reed V, Fisher G, Masson WK, Evans EP, Saunders JC, Crenshaw EB 3rd.

Hum Mol Genet. 2000 Jan 1;9(1):79-85.

PMID:
10587581
32.

Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear.

Phippard D, Lu L, Lee D, Saunders JC, Crenshaw EB 3rd.

J Neurosci. 1999 Jul 15;19(14):5980-9.

33.

Changes in the subcellular localization of the Brn4 gene product precede mesenchymal remodeling of the otic capsule.

Phippard D, Heydemann A, Lechner M, Lu L, Lee D, Kyin T, Crenshaw EB 3rd.

Hear Res. 1998 Jun;120(1-2):77-85.

PMID:
9667433
34.

Assignment of the gene for acetylcholinesterase to distal mouse chromosome 5.

Rachinsky TL, Crenshaw EB 3rd, Taylor P.

Genomics. 1992 Oct;14(2):511-4.

PMID:
1358806
35.

Wocko, a neurological mutant generated in a transgenic mouse pedigree.

Crenshaw EB 3rd, Ryan A, Dillon SR, Kalla K, Rosenfeld MG.

J Neurosci. 1991 Jun;11(6):1524-30.

36.

Gene expression in normal and abnormal inner ears.

Ryan AF, Crenshaw EB 3rd, Simmons DM.

Ann N Y Acad Sci. 1991;630:129-32. No abstract available.

PMID:
1683203
37.

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.

Li S, Crenshaw EB 3rd, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG.

Nature. 1990 Oct 11;347(6293):528-33.

PMID:
1977085
38.

A tissue-specific enhancer in the rat-calcitonin/CGRP gene is active in both neural and endocrine cell types.

Stolarsky-Fredman L, Leff SE, Klein ES, Crenshaw EB 3rd, Yeakley J, Rosenfeld MG.

Mol Endocrinol. 1990 Mar;4(3):497-504.

PMID:
2342482
39.
40.

Identification of rat growth hormone genomic sequences targeting pituitary expression in transgenic mice.

Lira SA, Crenshaw EB 3rd, Glass CK, Swanson LW, Rosenfeld MG.

Proc Natl Acad Sci U S A. 1988 Jul;85(13):4755-9.

41.

Neuronal expression of chimeric genes in transgenic mice.

Russo AF, Crenshaw EB 3rd, Lira SA, Simmons DM, Swanson LW, Rosenfeld MG.

Neuron. 1988 Jun;1(4):311-20.

PMID:
3078520
42.

Transgenic mice: applications to the study of the nervous system.

Rosenfeld MG, Crenshaw EB 3rd, Lira SA, Swanson L, Borrelli E, Heyman R, Evans RM.

Annu Rev Neurosci. 1988;11:353-72. Review. No abstract available.

PMID:
3284446
43.

Response and binding elements for ligand-dependent positive transcription factors integrate positive and negative regulation of gene expression.

Rosenfeld MG, Glass CK, Adler S, Crenshaw EB 3rd, He X, Lira SA, Elsholtz HP, Mangalam HJ, Holloway JM, Nelson C, et al.

Cold Spring Harb Symp Quant Biol. 1988;53 Pt 1:545-56. No abstract available.

PMID:
3254780
44.

Transcriptional and post-transcriptional strategies in neuroendocrine gene expression.

Rosenfeld M, Crenshaw EB 3rd, Emeson R, Leff S, Guise J, Lira S, Nelson C, Nelson C, Russo A.

Dev Biol (N Y 1985). 1988;5:317-34. Review. No abstract available.

PMID:
3077978
45.

Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene.

Crenshaw EB 3rd, Russo AF, Swanson LW, Rosenfeld MG.

Cell. 1987 May 8;49(3):389-98.

PMID:
3494523
46.

Developmental and hormonal regulation of neuroendocrine gene transcription.

Rosenfeld MG, Nelson C, Crenshaw EB 3rd, Elsholtz HP, Lira SA, Mangalam HJ, Franco R, Waterman M, Weinberger C, Hollenberg SM, et al.

Recent Prog Horm Res. 1987;43:499-534. Review. No abstract available.

PMID:
3306840
47.

Discrete cis-active genomic sequences dictate the pituitary cell type-specific expression of rat prolactin and growth hormone genes.

Nelson C, Crenshaw EB 3rd, Franco R, Lira SA, Albert VR, Evans RM, Rosenfeld MG.

Nature. 1986 Aug 7-13;322(6079):557-62.

PMID:
3736673
48.

Phagocytosis of gelatin-latex particles by a murine macrophage line is dependent on fibronectin and heparin.

van de Water L 3rd, Schroeder S, Crenshaw EB 3rd, Hynes RO.

J Cell Biol. 1981 Jul;90(1):32-9.

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