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Items: 31

1.

The synthesis and kinetic evaluation of aryl α-aminophosphonates as novel inhibitors of T. cruzi trans-sialidase.

Chen Z, Marcé P, Resende R, Alzari PM, Frasch AC, van den Elsen JMH, Crennell SJ, Watts AG.

Eur J Med Chem. 2018 Oct 5;158:25-33. doi: 10.1016/j.ejmech.2018.08.089. Epub 2018 Aug 31.

PMID:
30199703
2.

Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate.

Zaitsev V, Johnsen U, Reher M, Ortjohann M, Taylor GL, Danson MJ, Schönheit P, Crennell SJ.

Biochemistry. 2018 Jul 3;57(26):3797-3806. doi: 10.1021/acs.biochem.8b00535. Epub 2018 Jun 13.

PMID:
29812914
3.

Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.

Posner MG, Upadhyay A, Ishima R, Kalli AC, Harris G, Kremerskothen J, Sansom MSP, Crennell SJ, Bagby S.

J Biol Chem. 2018 Jun 15;293(24):9335-9344. doi: 10.1074/jbc.RA118.002279. Epub 2018 May 3.

4.

Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase.

Buddrus L, Andrews ESV, Leak DJ, Danson MJ, Arcus VL, Crennell SJ.

Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):179-186. doi: 10.1107/S2053230X18002819. Epub 2018 Feb 26.

5.

Structural insights of RmXyn10A - A prebiotic-producing GH10 xylanase with a non-conserved aglycone binding region.

Aronsson A, Güler F, Petoukhov MV, Crennell SJ, Svergun DI, Linares-Pastén JA, Nordberg Karlsson E.

Biochim Biophys Acta Proteins Proteom. 2018 Feb;1866(2):292-306. doi: 10.1016/j.bbapap.2017.11.006. Epub 2017 Nov 14.

6.

Structure of an acetylating aldehyde dehydrogenase from the thermophilic ethanologen Geobacillus thermoglucosidasius.

Extance J, Danson MJ, Crennell SJ.

Protein Sci. 2016 Nov;25(11):2045-2053. doi: 10.1002/pro.3027. Epub 2016 Sep 20.

7.

Crystal structure of pyruvate decarboxylase from Zymobacter palmae.

Buddrus L, Andrews ES, Leak DJ, Danson MJ, Arcus VL, Crennell SJ.

Acta Crystallogr F Struct Biol Commun. 2016 Sep;72(Pt 9):700-6. doi: 10.1107/S2053230X16012012. Epub 2016 Aug 26.

8.

Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.

Marrott NL, Marshall JJ, Svergun DI, Crennell SJ, Hough DW, van den Elsen JM, Danson MJ.

Biochem J. 2014 Nov 1;463(3):405-12. doi: 10.1042/BJ20140359.

PMID:
25088564
9.

Structures of mesophilic and extremophilic citrate synthases reveal rigidity and flexibility for function.

Wells SA, Crennell SJ, Danson MJ.

Proteins. 2014 Oct;82(10):2657-70. doi: 10.1002/prot.24630. Epub 2014 Jun 28.

PMID:
24948467
10.

A novel β-xylosidase structure from Geobacillus thermoglucosidasius: the first crystal structure of a glycoside hydrolase family GH52 enzyme reveals unpredicted similarity to other glycoside hydrolase folds.

Espina G, Eley K, Pompidor G, Schneider TR, Crennell SJ, Danson MJ.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1366-74. doi: 10.1107/S1399004714002788. Epub 2014 Apr 30.

PMID:
24816105
11.

Structure of a bifunctional alcohol dehydrogenase involved in bioethanol generation in Geobacillus thermoglucosidasius.

Extance J, Crennell SJ, Eley K, Cripps R, Hough DW, Danson MJ.

Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):2104-15. doi: 10.1107/S0907444913020349. Epub 2013 Sep 20.

PMID:
24100328
12.

Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation.

Posner MG, Upadhyay A, Crennell SJ, Watson AJ, Dorus S, Danson MJ, Bagby S.

Biochem J. 2013 Jan 15;449(2):415-25. doi: 10.1042/BJ20121150.

PMID:
23116157
13.

The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly.

Marrott NL, Marshall JJ, Svergun DI, Crennell SJ, Hough DW, Danson MJ, van den Elsen JM.

FEBS J. 2012 Mar;279(5):713-23. doi: 10.1111/j.1742-4658.2011.08461.x. Epub 2012 Jan 19.

14.

Contribution of inter-subunit interactions to the thermostability of Pyrococcus furiosus citrate synthase.

Moore V, Kanu A, Byron O, Campbell G, Danson MJ, Hough DW, Crennell SJ.

Extremophiles. 2011 May;15(3):327-36. doi: 10.1007/s00792-011-0363-6. Epub 2011 Mar 20.

PMID:
21424517
15.

A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d.

Clark EA, Crennell S, Upadhyay A, Zozulya AV, Mackay JD, Svergun DI, Bagby S, van den Elsen JM.

Mol Immunol. 2011 Jan;48(4):452-62. doi: 10.1016/j.molimm.2010.09.017. Epub 2010 Nov 4.

16.

Structurally informed site-directed mutagenesis of a stereochemically promiscuous aldolase to afford stereochemically complementary biocatalysts.

Royer SF, Haslett L, Crennell SJ, Hough DW, Danson MJ, Bull SD.

J Am Chem Soc. 2010 Aug 25;132(33):11753-8. doi: 10.1021/ja104412a.

PMID:
20684556
17.

Germline humanization of a non-human primate antibody that neutralizes the anthrax toxin, by in vitro and in silico engineering.

Pelat T, Bedouelle H, Rees AR, Crennell SJ, Lefranc MP, Thullier P.

J Mol Biol. 2008 Dec 31;384(5):1400-7. doi: 10.1016/j.jmb.2008.10.033. Epub 2008 Oct 19.

PMID:
18976662
18.

Identification of amino acids essential for catalytic activity of pneumococcal neuraminidase A.

Yesilkaya H, Soma-Haddrick S, Crennell SJ, Andrew PW.

Res Microbiol. 2006 Jul-Aug;157(6):569-74. Epub 2006 Feb 13.

PMID:
16844348
19.
20.

Citrate synthase from Thermus aquaticus: a thermostable bacterial enzyme with a five-membered inter-subunit ionic network.

Nordberg Karlsson E, Crennell SJ, Higgins C, Nawaz S, Yeoh L, Hough DW, Danson MJ.

Extremophiles. 2003 Feb;7(1):9-16. Epub 2002 Sep 7.

PMID:
12579375
21.

Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxovirus-cell membrane fusion.

Takimoto T, Taylor GL, Connaris HC, Crennell SJ, Portner A.

J Virol. 2002 Dec;76(24):13028-33.

22.

The structure of Rhodothermus marinus Cel12A, a highly thermostable family 12 endoglucanase, at 1.8 A resolution.

Crennell SJ, Hreggvidsson GO, Nordberg Karlsson E.

J Mol Biol. 2002 Jul 19;320(4):883-97.

PMID:
12095262
23.
24.

Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase.

Crennell S, Takimoto T, Portner A, Taylor G.

Nat Struct Biol. 2000 Nov;7(11):1068-74.

PMID:
11062565
25.

The predicted structure of photopexin from Photorhabdus shows the first haemopexin-like motif in prokaryotes.

Crennell SJ, Tickler PM, Bowen DJ, ffrench-Constant RH.

FEMS Microbiol Lett. 2000 Oct 1;191(1):139-44.

26.

Crystallization of Newcastle disease virus hemagglutinin-neuraminidase glycoprotein.

Takimoto T, Taylor GL, Crennell SJ, Scroggs RA, Portner A.

Virology. 2000 Apr 25;270(1):208-14.

27.

The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution.

Crennell SJ, Garman EF, Philippon C, Vasella A, Laver WG, Vimr ER, Taylor GL.

J Mol Biol. 1996 Jun 7;259(2):264-80.

PMID:
8656428
28.
29.

Crystal structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain.

Crennell S, Garman E, Laver G, Vimr E, Taylor G.

Structure. 1994 Jun 15;2(6):535-44.

PMID:
7922030
30.

The crystal structure of glucose dehydrogenase from Thermoplasma acidophilum.

John J, Crennell SJ, Hough DW, Danson MJ, Taylor GL.

Structure. 1994 May 15;2(5):385-93. Erratum in: Structure 1994 Aug 15;2(8):784.

PMID:
8081754
31.

Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza virus neuraminidase.

Crennell SJ, Garman EF, Laver WG, Vimr ER, Taylor GL.

Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):9852-6.

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