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Items: 1 to 50 of 73

1.

Differentiating between Testicular Toxicity and Sexual Immaturity in Ortho-phthalaldehyde Inhalation Toxicity Studies in Rats and Mice.

Catlin NR, Willson CJ, Creasy DM, Rao DB, Kissling GE, McIntyre BS, Wyde M.

Toxicol Pathol. 2018 Oct;46(7):753-763. doi: 10.1177/0192623318801790. Epub 2018 Sep 27.

2.

High Background Incidence of Spontaneous Subcapsular Adrenal Gland Hyperplasia of Tg.rasH2 Mice Used in 26-week Carcinogenicity Studies.

Boyle MH, Paranjpe MG, Creasy DM.

Toxicol Pathol. 2018 Jun;46(4):444-448. doi: 10.1177/0192623318770965. Epub 2018 Apr 25.

PMID:
29695215
3.

Testicular Fibrous Hypoplasia in Cynomolgus Monkeys ( Macaca fascicularis): An Incidental, Congenital Lesion.

Pereira Bacares ME, Vemireddi V, Creasy D.

Toxicol Pathol. 2017 Jun;45(4):536-543. doi: 10.1177/0192623317709539. Epub 2017 Jun 2.

PMID:
28573934
4.

Recommendations from the INHAND Apoptosis/Necrosis Working Group.

Elmore SA, Dixon D, Hailey JR, Harada T, Herbert RA, Maronpot RR, Nolte T, Rehg JE, Rittinghausen S, Rosol TJ, Satoh H, Vidal JD, Willard-Mack CL, Creasy DM.

Toxicol Pathol. 2016 Feb;44(2):173-88. doi: 10.1177/0192623315625859. Epub 2016 Feb 14.

5.

Scientific and Regulatory Policy Committee (SRPC) Points to Consider: Histopathology Evaluation of the Pubertal Development and Thyroid Function Assay (OPPTS 890.1450, OPPTS 890.1500) in Rats to Screen for Endocrine Disruptors.

Keane KA, Parker GA, Regan KS, Picut C, Dixon D, Creasy D, Giri D, Hukkanen RR.

Toxicol Pathol. 2015 Dec;43(8):1047-63. doi: 10.1177/0192623315579943. Epub 2015 May 6.

6.

Testicular and epididymal toxicity: Pathogenesis and potential mechanisms of toxicity.

Creasy DM, Chapin RE.

Spermatogenesis. 2015 Jan 13;4(2):e1005511. eCollection 2014 May-Aug. No abstract available.

7.

Effects of male sexual maturity of reproductive endpoints relevant to DART studies in Wistar Hannover rats.

Takakura I, Creasy DM, Yokoi R, Terashima Y, Onozato T, Maruyama Y, Chino T, Tahara T, Tamura T, Kuroda J, Kusama H.

J Toxicol Sci. 2014 Apr;39(2):269-79.

8.

Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment.

Everds NE, Snyder PW, Bailey KL, Bolon B, Creasy DM, Foley GL, Rosol TJ, Sellers T.

Toxicol Pathol. 2013;41(4):560-614. doi: 10.1177/0192623312466452. Epub 2013 Mar 7. Review.

PMID:
23475558
9.

Computational proteomics pitfalls and challenges: HavanaBioinfo 2012 workshop report.

Perez-Riverol Y, Hermjakob H, Kohlbacher O, Martens L, Creasy D, Cox J, Leprevost F, Shan BP, Pérez-Nueno VI, Blazejczyk M, Punta M, Vierlinger K, Valiente PA, Leon K, Chinea G, Guirola O, Bringas R, Cabrera G, Guillen G, Padron G, Gonzalez LJ, Besada V.

J Proteomics. 2013 Jul 11;87:134-8. doi: 10.1016/j.jprot.2013.01.019. Epub 2013 Jan 29.

PMID:
23376229
10.

John Cottrell, David Creasy & Darryl Pappin. Interview by H. Craig Mak.

Cottrell J, Creasy D, Pappin D.

Nat Biotechnol. 2012 Oct;30(10):963. doi: 10.1038/nbt.2393. No abstract available.

PMID:
23051816
11.

A cross-platform toolkit for mass spectrometry and proteomics.

Chambers MC, Maclean B, Burke R, Amodei D, Ruderman DL, Neumann S, Gatto L, Fischer B, Pratt B, Egertson J, Hoff K, Kessner D, Tasman N, Shulman N, Frewen B, Baker TA, Brusniak MY, Paulse C, Creasy D, Flashner L, Kani K, Moulding C, Seymour SL, Nuwaysir LM, Lefebvre B, Kuhlmann F, Roark J, Rainer P, Detlev S, Hemenway T, Huhmer A, Langridge J, Connolly B, Chadick T, Holly K, Eckels J, Deutsch EW, Moritz RL, Katz JE, Agus DB, MacCoss M, Tabb DL, Mallick P.

Nat Biotechnol. 2012 Oct;30(10):918-20. doi: 10.1038/nbt.2377. No abstract available.

12.

Testosterone deficiency accompanied by testicular and epididymal abnormalities in TMF(-/-) mice.

Elkis Y, Bel S, Lerer-Goldstein T, Nyska A, Creasy DM, Shpungin S, Nir U.

Mol Cell Endocrinol. 2013 Jan 5;365(1):52-63. doi: 10.1016/j.mce.2012.09.003. Epub 2012 Sep 20.

PMID:
23000399
13.

Proliferative and nonproliferative lesions of the rat and mouse male reproductive system.

Creasy D, Bube A, de Rijk E, Kandori H, Kuwahara M, Masson R, Nolte T, Reams R, Regan K, Rehm S, Rogerson P, Whitney K.

Toxicol Pathol. 2012 Aug;40(6 Suppl):40S-121S. doi: 10.1177/0192623312454337. Review.

PMID:
22949412
14.

A dose response study to assess effects after dietary administration of diisononyl phthalate (DINP) in gestation and lactation on male rat sexual development.

Clewell RA, Thomas A, Willson G, Creasy DM, Andersen ME.

Reprod Toxicol. 2013 Jan;35:70-80. doi: 10.1016/j.reprotox.2012.07.008. Epub 2012 Aug 18.

PMID:
22944045
15.

Disposition of diiosononyl phthalate and its effects on sexual development of the male fetus following repeated dosing in pregnant rats.

Clewell RA, Sochaski M, Edwards K, Creasy DM, Willson G, Andersen ME.

Reprod Toxicol. 2013 Jan;35:56-69. doi: 10.1016/j.reprotox.2012.07.001. Epub 2012 Jul 17.

PMID:
22813627
16.

Society of toxicologic pathology position paper: review series: assessment of circulating hormones in nonclinical toxicity studies: general concepts and considerations.

Stanislaus D, Andersson H, Chapin R, Creasy D, Ferguson D, Gilbert M, Rosol TJ, Boyce RW, Wood CE.

Toxicol Pathol. 2012 Aug;40(6):943-50. doi: 10.1177/0192623312444622. Epub 2012 May 8. Review.

PMID:
22569585
17.

Assessment of circulating hormones in regulatory toxicity studies II. Male reproductive hormones.

Chapin RE, Creasy DM.

Toxicol Pathol. 2012 Oct;40(7):1063-78. Epub 2012 May 2.

PMID:
22552397
18.

Efferent duct toxicity with secondary testicular changes in rats following administration of a novel leukotriene A₄ hydrolase inhibitor.

La DK, Creasy DM, Hess RA, Baxter E, Pereira ME, Johnson CA, Vinken P, Snook SS.

Toxicol Pathol. 2012 Jul;40(5):705-14. doi: 10.1177/0192623312441412. Epub 2012 May 2.

PMID:
22552396
19.

The mzIdentML data standard for mass spectrometry-based proteomics results.

Jones AR, Eisenacher M, Mayer G, Kohlbacher O, Siepen J, Hubbard SJ, Selley JN, Searle BC, Shofstahl J, Seymour SL, Julian R, Binz PA, Deutsch EW, Hermjakob H, Reisinger F, Griss J, Vizcaíno JA, Chambers M, Pizarro A, Creasy D.

Mol Cell Proteomics. 2012 Jul;11(7):M111.014381. doi: 10.1074/mcp.M111.014381. Epub 2012 Feb 27.

20.

Response to: the problem with peptide presumption and low Mascot scoring.

Cottrell JS, Creasy DM.

J Proteome Res. 2011 Nov 4;10(11):5272-3. doi: 10.1021/pr200726c. Epub 2011 Sep 29.

PMID:
21942731
21.

Commentary on incidence and nature of testicular toxicity findings in pharmaceutical development survey: a pathologist's perspective.

Creasy DM.

Birth Defects Res B Dev Reprod Toxicol. 2011 Dec;92(6):508-10. doi: 10.1002/bdrb.20323. Epub 2011 Aug 4. No abstract available.

PMID:
21818841
22.

Evaluation of the rabbit nasal cavity in inhalation studies and a comparison with other common laboratory species and man.

Pereira ME, Macri NP, Creasy DM.

Toxicol Pathol. 2011 Aug;39(5):893-900. doi: 10.1177/0192623311409594. Epub 2011 May 31.

PMID:
21628717
23.

Hierarchical clustering of shotgun proteomics data.

Koskinen VR, Emery PA, Creasy DM, Cottrell JS.

Mol Cell Proteomics. 2011 Jun;10(6):M110.003822. doi: 10.1074/mcp.M110.003822. Epub 2011 Mar 29.

24.

Annual spring meeting of the Proteomics Standards Initiative.

Orchard S, Deutsch EW, Binz PA, Jones AR, Creasy D, Montechi-Palazzi L, Corthals G, Hermjakob H.

Proteomics. 2009 Oct;9(19):4429-32. doi: 10.1002/pmic.200900407.

PMID:
19670378
25.

A lifetime cancer bioassay of quinacrine administered into the uterine horns of female rats.

Cancel AM, Dillberger JE, Kelly CM, Bolte HF, Creasy DM, Sokal DC.

Regul Toxicol Pharmacol. 2010 Mar;56(2):156-65. doi: 10.1016/j.yrtph.2009.07.008. Epub 2009 Jul 23.

PMID:
19631709
26.

Annual spring meeting of the Proteomics Standards Initiative 23-25 April 2008, Toledo, Spain.

Orchard S, Albar JP, Deutsch EW, Binz PA, Jones AR, Creasy D, Hermjakob H.

Proteomics. 2008 Oct;8(20):4168-72. doi: 10.1002/pmic.200800555.

PMID:
18814335
27.

The PSI-MOD community standard for representation of protein modification data.

Montecchi-Palazzi L, Beavis R, Binz PA, Chalkley RJ, Cottrell J, Creasy D, Shofstahl J, Seymour SL, Garavelli JS.

Nat Biotechnol. 2008 Aug;26(8):864-6. doi: 10.1038/nbt0808-864. No abstract available.

PMID:
18688235
28.

Guidelines for reporting the use of mass spectrometry informatics in proteomics.

Binz PA, Barkovich R, Beavis RC, Creasy D, Horn DM, Julian RK Jr, Seymour SL, Taylor CF, Vandenbrouck Y.

Nat Biotechnol. 2008 Aug;26(8):862. doi: 10.1038/nbt0808-862. No abstract available.

PMID:
18688233
29.

Five years of progress in the Standardization of Proteomics Data 4th Annual Spring Workshop of the HUPO-Proteomics Standards Initiative April 23-25, 2007 Ecole Nationale Supérieure (ENS), Lyon, France.

Orchard S, Montechi-Palazzi L, Deutsch EW, Binz PA, Jones AR, Paton N, Pizarro A, Creasy DM, Wojcik J, Hermjakob H.

Proteomics. 2007 Oct;7(19):3436-40.

PMID:
17907277
30.

STP position paper: ovarian follicular counting in the assessment of rodent reproductive toxicity.

Regan KS, Cline JM, Creasy D, Davis B, Foley GL, Lanning L, Latendresse JR, Makris S, Morton D, Rehm S, Stebbins K; STP Ovary Evaluation Working Group.

Toxicol Pathol. 2005;33(3):409-12. No abstract available.

PMID:
15805082
31.

Unimod: Protein modifications for mass spectrometry.

Creasy DM, Cottrell JS.

Proteomics. 2004 Jun;4(6):1534-6.

PMID:
15174123
32.
33.

Error tolerant searching of uninterpreted tandem mass spectrometry data.

Creasy DM, Cottrell JS.

Proteomics. 2002 Oct;2(10):1426-34.

PMID:
12422359
34.

Histopathology of the male reproductive system II: interpretation.

Creasy DM.

Curr Protoc Toxicol. 2002 Nov;Chapter 16:Unit16.4. doi: 10.1002/0471140856.tx1604s13.

PMID:
20963756
35.

Fixation of testes and eyes using a modified Davidson's fluid: comparison with Bouin's fluid and conventional Davidson's fluid.

Latendresse JR, Warbrittion AR, Jonassen H, Creasy DM.

Toxicol Pathol. 2002 Jul-Aug;30(4):524-33.

PMID:
12187944
36.

Recommended approaches for the evaluation of testicular and epididymal toxicity.

Lanning LL, Creasy DM, Chapin RE, Mann PC, Barlow NJ, Regan KS, Goodman DG.

Toxicol Pathol. 2002 Jul-Aug;30(4):507-20. No abstract available.

PMID:
12187942
37.

Oral (drinking water) two-generation reproductive toxicity study of dibromoacetic acid (DBA) in rats.

Christian MS, York RG, Hoberman AM, Frazee J, Fisher LC, Brown WR, Creasy DM.

Int J Toxicol. 2002 Jul-Aug;21(4):237-76.

PMID:
12171628
38.

Histopathology of the male reproductive system I: techniques.

Creasy DM.

Curr Protoc Toxicol. 2002 Aug;Chapter 16:Unit16.3. doi: 10.1002/0471140856.tx1603s12.

PMID:
20963755
39.

Matching peptide mass spectra to EST and genomic DNA databases.

Choudhary JS, Blackstock WP, Creasy DM, Cottrell JS.

Trends Biotechnol. 2001 Oct;19(10 Suppl):S17-22. Review.

PMID:
11780965
40.

Interrogating the human genome using uninterpreted mass spectrometry data.

Choudhary JS, Blackstock WP, Creasy DM, Cottrell JS.

Proteomics. 2001 May;1(5):651-67. Erratum in: Proteomics 2001 Jun;1(6):796.

PMID:
11678035
41.

Pathogenesis of male reproductive toxicity.

Creasy DM.

Toxicol Pathol. 2001 Jan-Feb;29(1):64-76. Review.

PMID:
11215686
42.

Two-generation reproduction toxicity studies of di-(C(7)-C(9) alkyl) phthalate and di-(C(9)-C(11) alkyl) phthalate in the rat.

Willoughby CR, Fulcher SM, Creasy DM, Heath JA, Priston RA, Moore NP.

Reprod Toxicol. 2000 Sep-Oct;14(5):427-50.

PMID:
11020654
43.

Probability-based protein identification by searching sequence databases using mass spectrometry data.

Perkins DN, Pappin DJ, Creasy DM, Cottrell JS.

Electrophoresis. 1999 Dec;20(18):3551-67.

PMID:
10612281
44.

Subacute and chronic toxicity studies of triethylenetetramine dihydrochloride (TJA-250) by oral administration to F-344 rats.

Yanagisawa T, Maemura S, Sasaki H, Endo T, Okada M, East PW, Virgo DM, Creasy DM.

J Toxicol Sci. 1998 Oct;23 Suppl 4:619-42.

PMID:
9836186
45.
46.

A 90-day feeding study of lupin (Lupinus angustifolius) flour spiked with lupin alkaloids in the rat.

Butler WH, Ford GP, Creasy DM.

Food Chem Toxicol. 1996 Jun;34(6):531-6.

PMID:
8690312
47.

Comparison of urinary creatine with other biomarkers for the detection of 2-methoxyethanol-induced testicular damage.

Draper RP, Creasy DM, Timbrell JA.

Biomarkers. 1996;1(3):190-5. doi: 10.3109/13547509609079356.

PMID:
23902324
48.

Monitoring spermatogenesis.

Creasy DM.

Hum Exp Toxicol. 1995 Jan;14(1):70-1. No abstract available.

PMID:
7748620
49.

The detection of subchronic testicular damage using urinary creatine: studies with 2-methoxyethanol.

Butterworth M, Creasy D, Timbrell JA.

Arch Toxicol. 1995;69(3):209-11.

PMID:
7717879
50.

A 28-day feeding study with ethyl acetoacetate in rats.

Cook WM, Purchase R, Ford GP, Creasy DM, Brantom PG, Gangolli SD.

Food Chem Toxicol. 1992 Jul;30(7):567-73.

PMID:
1521830

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