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Items: 28

1.

Caspase-11-Mediated Cell Death Contributes to the Pathogenesis of Imiquimod-Induced Psoriasis.

Kenealy S, Manils J, Raverdeau M, Munoz-Wolf N, Barber G, Liddicoat A, Lavelle EC, Creagh EM.

J Invest Dermatol. 2019 Jun 5. pii: S0022-202X(19)31624-0. doi: 10.1016/j.jid.2019.05.010. [Epub ahead of print] No abstract available.

2.

Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis.

Flood B, Manils J, Nulty C, Flis E, Kenealy S, Barber G, Fay J, Mills KHG, Kay EW, Creagh EM.

Oncogene. 2019 Apr;38(14):2658-2674. doi: 10.1038/s41388-018-0613-5. Epub 2018 Dec 11.

3.

Emerging methods in colorectal cancer screening.

Ryan EJ, Creagh EM.

Br J Surg. 2018 Jan;105(2):e16-e18. doi: 10.1002/bjs.10650. No abstract available.

PMID:
29341154
4.

RAB39a binds caspase-1 and is required for caspase-1-dependent interleukin-1β secretion.

Becker CE, Creagh EM, O'Neill LA.

J Biol Chem. 2016 Nov 18;291(47):24800. No abstract available.

5.

Suppression of human alloreactive T cells by linear tetrapyrroles; relevance for transplantation.

Basdeo SA, Campbell NK, Sullivan LM, Flood B, Creagh EM, Mantle TJ, Fletcher JM, Dunne A.

Transl Res. 2016 Dec;178:81-94.e2. doi: 10.1016/j.trsl.2016.07.011. Epub 2016 Jul 21.

PMID:
27497182
6.

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential.

Flood B, Oficjalska K, Laukens D, Fay J, O'Grady A, Caiazza F, Heetun Z, Mills KH, Sheahan K, Ryan EJ, Doherty GA, Kay E, Creagh EM.

Clin Exp Immunol. 2015 Jul;181(1):39-50. doi: 10.1111/cei.12617. Epub 2015 May 6.

7.

Protective role for caspase-11 during acute experimental murine colitis.

Oficjalska K, Raverdeau M, Aviello G, Wade SC, Hickey A, Sheehan KM, Corr SC, Kay EW, O'Neill LA, Mills KH, Creagh EM.

J Immunol. 2015 Feb 1;194(3):1252-60. doi: 10.4049/jimmunol.1400501. Epub 2014 Dec 29.

8.

Caspase crosstalk: integration of apoptotic and innate immune signalling pathways.

Creagh EM.

Trends Immunol. 2014 Dec;35(12):631-640. doi: 10.1016/j.it.2014.10.004. Epub 2014 Nov 10. Review.

PMID:
25457353
9.

Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.

Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, Lambe EM, Creagh EM, Golenbock DT, Tschopp J, Kornfeld H, Fitzgerald KA, Lavelle EC.

J Biol Chem. 2011 Mar 18;286(11):9587-97. doi: 10.1074/jbc.M110.202911. Epub 2011 Jan 12.

10.

The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.

Lavelle EC, Murphy C, O'Neill LA, Creagh EM.

Mucosal Immunol. 2010 Jan;3(1):17-28. doi: 10.1038/mi.2009.124. Epub 2009 Nov 4. Review.

11.

Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion.

Becker CE, Creagh EM, O'Neill LA.

J Biol Chem. 2009 Dec 11;284(50):34531-7. doi: 10.1074/jbc.M109.046102. Epub 2009 Oct 15. Erratum in: J Biol Chem. 2016 Nov 18;291(47):24800.

12.

Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival.

Creagh EM, Brumatti G, Sheridan C, Duriez PJ, Taylor RC, Cullen SP, Adrain C, Martin SJ.

PLoS One. 2009;4(3):e5055. doi: 10.1371/journal.pone.0005055. Epub 2009 Mar 30. Erratum in: PLoS ONE. 2009;4(3). doi: 10.1371/annotation/dbafbfb3-0c37-4e20-931a-8f041ff5d721.

13.

TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity.

Creagh EM, O'Neill LA.

Trends Immunol. 2006 Aug;27(8):352-7. Epub 2006 Jun 27.

PMID:
16807108
14.

Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man.

Adrain C, Creagh EM, Cullen SP, Martin SJ.

J Biol Chem. 2004 Aug 27;279(35):36923-30. Epub 2004 Jun 21.

15.

Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation.

Murphy BM, Creagh EM, Martin SJ.

J Biol Chem. 2004 Aug 27;279(35):36916-22. Epub 2004 Jun 21.

16.

Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes.

Hill MM, Adrain C, Duriez PJ, Creagh EM, Martin SJ.

EMBO J. 2004 May 19;23(10):2134-45. Epub 2004 Apr 22.

17.

Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins.

Creagh EM, Murphy BM, Duriez PJ, Duckett CS, Martin SJ.

J Biol Chem. 2004 Jun 25;279(26):26906-14. Epub 2004 Apr 12.

18.

Caspase-activation pathways in apoptosis and immunity.

Creagh EM, Conroy H, Martin SJ.

Immunol Rev. 2003 Jun;193:10-21. Review.

PMID:
12752666
19.

Cell stress-associated caspase activation: intrinsically complex?

Creagh EM, Martin SJ.

Sci STKE. 2003 Mar 25;2003(175):pe11. Review.

PMID:
12657730
20.

Defying death: showing Bcl-2 the way home.

Adrain C, Creagh EM, Martin SJ.

Nat Cell Biol. 2003 Jan;5(1):9-11. No abstract available.

PMID:
12511882
21.
22.

Caspases: cellular demolition experts.

Creagh EM, Martin SJ.

Biochem Soc Trans. 2001 Nov;29(Pt 6):696-702. Review.

PMID:
11709057
23.

CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways.

Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh EM, MacFarlane M, Martin SJ.

J Biol Chem. 2001 Nov 23;276(47):44069-77. Epub 2001 Sep 10.

24.

Heat shock proteins--modulators of apoptosis in tumour cells.

Creagh EM, Sheehan D, Cotter TG.

Leukemia. 2000 Jul;14(7):1161-73. Review.

PMID:
10914538
25.

Heat shock protein 70 inhibits caspase-dependent and -independent apoptosis in Jurkat T cells.

Creagh EM, Carmody RJ, Cotter TG.

Exp Cell Res. 2000 May 25;257(1):58-66.

PMID:
10854054
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28.

Effects of hypocapnia and hypocapnic alkalosis on cardiovascular function.

Zwillich CW, Pierson DJ, Creagh EM, Weil JV.

J Appl Physiol. 1976 Mar;40(3):333-7.

PMID:
931846

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