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Items: 45

1.

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors.

Kalathottukaren MT, Creagh AL, Abbina S, Lu G, Karbarz MJ, Pandey A, Conley PB, Kizhakkedathu JN, Haynes C.

Blood Adv. 2018 Aug 28;2(16):2104-2114. doi: 10.1182/bloodadvances.2016003616.

2.

A Polymer Therapeutic Having Universal Heparin Reversal Activity: Molecular Design and Functional Mechanism.

Kalathottukaren MT, Abbina S, Yu K, Shenoi RA, Creagh AL, Haynes C, Kizhakkedathu JN.

Biomacromolecules. 2017 Oct 9;18(10):3343-3358. doi: 10.1021/acs.biomac.7b00994. Epub 2017 Sep 19.

PMID:
28880550
3.

Interactions of U24 from Roseolovirus with WW domains: canonical vs noncanonical.

Sang Y, Zhang R, Creagh AL, Haynes CA, Straus SK.

Biochem Cell Biol. 2017 Jun;95(3):350-358. doi: 10.1139/bcb-2016-0250. Epub 2017 Mar 17.

PMID:
28314105
4.

U24 from Roseolovirus interacts strongly with Nedd4 WW Domains.

Sang Y, Zhang R, Scott WR, Creagh AL, Haynes CA, Straus SK.

Sci Rep. 2017 Jan 4;7:39776. doi: 10.1038/srep39776.

5.

Iron Binding and Iron Removal Efficiency of Desferrioxamine Based Polymeric Iron Chelators: Influence of Molecular Size and Chelator Density.

Hamilton JL, Ul-Haq MI, Creagh AL, Haynes CA, Kizhakkedathu JN.

Macromol Biosci. 2017 Mar;17(3). doi: 10.1002/mabi.201600244. Epub 2016 Sep 28.

PMID:
27683190
6.

Molecular Dissection of Xyloglucan Recognition in a Prominent Human Gut Symbiont.

Tauzin AS, Kwiatkowski KJ, Orlovsky NI, Smith CJ, Creagh AL, Haynes CA, Wawrzak Z, Brumer H, Koropatkin NM.

MBio. 2016 Apr 26;7(2):e02134-15. doi: 10.1128/mBio.02134-15.

7.

Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry.

Yu K, Creagh AL, Haynes CA, Kizhakkedathu JN.

Methods Mol Biol. 2016;1367:183-93. doi: 10.1007/978-1-4939-3130-9_15.

PMID:
26537474
8.

In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders.

Cawthray JF, Weekes DM, Sivak O, Creagh AL, Ibrahim F, Iafrate M, Haynes CA, Wasan KM, Orvig C.

Chem Sci. 2015 Nov 1;6(11):6439-6447. doi: 10.1039/c5sc01767j. Epub 2015 Aug 3.

9.

Ion exchange in hydroxyapatite with lanthanides.

Cawthray JF, Creagh AL, Haynes CA, Orvig C.

Inorg Chem. 2015 Feb 16;54(4):1440-5. doi: 10.1021/ic502425e. Epub 2015 Jan 16.

PMID:
25594577
10.

Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.

Shenoi RA, Kalathottukaren MT, Travers RJ, Lai BF, Creagh AL, Lange D, Yu K, Weinhart M, Chew BH, Du C, Brooks DE, Carter CJ, Morrissey JH, Haynes CA, Kizhakkedathu JN.

Sci Transl Med. 2014 Oct 29;6(260):260ra150. doi: 10.1126/scitranslmed.3009427. Epub 2014 Oct 29.

11.

Probing the interaction between U24 and the SH3 domain of Fyn tyrosine kinase.

Sang Y, Tait AR, Scott WR, Creagh AL, Kumar P, Haynes CA, Straus SK.

Biochemistry. 2014 Sep 30;53(38):6092-102. doi: 10.1021/bi500945x. Epub 2014 Sep 16.

PMID:
25225878
12.

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes.

Larsbrink J, Rogers TE, Hemsworth GR, McKee LS, Tauzin AS, Spadiut O, Klinter S, Pudlo NA, Urs K, Koropatkin NM, Creagh AL, Haynes CA, Kelly AG, Cederholm SN, Davies GJ, Martens EC, Brumer H.

Nature. 2014 Feb 27;506(7489):498-502. doi: 10.1038/nature12907. Epub 2014 Jan 19.

13.

A new mixed-mode model for interpreting and predicting protein elution during isoelectric chromatofocusing.

Choy DY, Creagh AL, von Lieres E, Haynes C.

Biotechnol Bioeng. 2014 May;111(5):925-36. doi: 10.1002/bit.25166. Epub 2014 Jan 17.

PMID:
24293057
14.

Improved isoelectric focusing chromatography on strong anion exchange media via a new model that custom designs mobile phases using simple buffers.

Choy DY, Creagh AL, Haynes C.

Biotechnol Bioeng. 2014 Mar;111(3):552-64. doi: 10.1002/bit.25122. Epub 2013 Oct 25.

PMID:
24166014
15.

Lectin interactions on surface-grafted glycostructures: influence of the spatial distribution of carbohydrates on the binding kinetics and rupture forces.

Yu K, Creagh AL, Haynes CA, Kizhakkedathu JN.

Anal Chem. 2013 Aug 20;85(16):7786-93. doi: 10.1021/ac401306b. Epub 2013 Aug 9.

PMID:
23931124
16.

The Mannoprotein Cig1 supports iron acquisition from heme and virulence in the pathogenic fungus Cryptococcus neoformans.

Cadieux B, Lian T, Hu G, Wang J, Biondo C, Teti G, Liu V, Murphy ME, Creagh AL, Kronstad JW.

J Infect Dis. 2013 Apr 15;207(8):1339-47. doi: 10.1093/infdis/jit029. Epub 2013 Jan 15.

17.

High molecular weight polyglycerol-based multivalent mannose conjugates.

Kizhakkedathu JN, Creagh AL, Shenoi RA, Rossi NA, Brooks DE, Chan T, Lam J, Dandepally SR, Haynes CA.

Biomacromolecules. 2010 Oct 11;11(10):2567-75. doi: 10.1021/bm1004788.

PMID:
20804173
18.

The induction of thrombus generation on nanostructured neutral polymer brush surfaces.

Lai BF, Creagh AL, Janzen J, Haynes CA, Brooks DE, Kizhakkedathu JN.

Biomaterials. 2010 Sep;31(26):6710-8.

PMID:
20641167
19.

The induction of thrombus generation on nanostructured neutral polymer brush surfaces.

Lai BF, Creagh AL, Janzen J, Haynes CA, Brooks DE, Kizhakkedathu JN.

Biomaterials. 2010 Sep;31(26):6710-6718. Epub 2010 Jun 20.

PMID:
20638975
20.

Topical delivery of interferon alpha by biphasic vesicles: evidence for a novel nanopathway across the stratum corneum.

Foldvari M, Badea I, Wettig S, Baboolal D, Kumar P, Creagh AL, Haynes CA.

Mol Pharm. 2010 Jun 7;7(3):751-62. doi: 10.1021/mp900283x.

PMID:
20349952
21.

Direct measurement of the kinetics of CBM9 fusion-tag bioprocessing using luminescence resonance energy transfer.

Kavoosi M, Creagh AL, Turner RF, Kilburn DG, Haynes CA.

Biotechnol Prog. 2009 May-Jun;25(3):874-81. doi: 10.1002/btpr.88.

PMID:
19496182
22.

Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin.

Bordbar AK, Creagh AL, Mohammadi F, Haynes CA, Orvig C.

J Inorg Biochem. 2009 Apr;103(4):643-7. doi: 10.1016/j.jinorgbio.2008.10.009. Epub 2008 Oct 17.

PMID:
19056126
23.

Structural characterization of the type-III pilot-secretin complex from Shigella flexneri.

Okon M, Moraes TF, Lario PI, Creagh AL, Haynes CA, Strynadka NC, McIntosh LP.

Structure. 2008 Oct 8;16(10):1544-54. doi: 10.1016/j.str.2008.08.006.

24.

The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR.

Wilke MS, Heller M, Creagh AL, Haynes CA, McIntosh LP, Poole K, Strynadka NC.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14832-7. doi: 10.1073/pnas.0805489105. Epub 2008 Sep 23.

25.

Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus.

Thomson CA, Bryson S, McLean GR, Creagh AL, Pai EF, Schrader JW.

EMBO J. 2008 Oct 8;27(19):2592-602. doi: 10.1038/emboj.2008.179. Epub 2008 Sep 4.

26.

Strategy for selecting and characterizing linker peptides for CBM9-tagged fusion proteins expressed in Escherichia coli.

Kavoosi M, Creagh AL, Kilburn DG, Haynes CA.

Biotechnol Bioeng. 2007 Oct 15;98(3):599-610.

PMID:
17394253
27.

Calorimetric studies of melanotransferrin (p97) and its interaction with iron.

Creagh AL, Tiong JW, Tian MM, Haynes CA, Jefferies WA.

J Biol Chem. 2005 Apr 22;280(16):15735-41. Epub 2005 Feb 9.

28.

Inexpensive and generic affinity purification of recombinant proteins using a family 2a CBM fusion tag.

Rodriguez B, Kavoosi M, Koska J, Creagh AL, Kilburn DG, Haynes CA.

Biotechnol Prog. 2004 Sep-Oct;20(5):1479-89.

PMID:
15458333
29.

Specificity of the synergistic anion for iron binding by ferric binding protein from Neisseria gonorrhoeae.

Bekker EG, Creagh AL, Sanaie N, Yumoto F, Lau GH, Tanokura M, Haynes CA, Murphy ME.

Biochemistry. 2004 Jul 20;43(28):9195-203.

PMID:
15248777
30.

Inexpensive one-step purification of polypeptides expressed in Escherichia coli as fusions with the family 9 carbohydrate-binding module of xylanase 10A from T. maritima.

Kavoosi M, Meijer J, Kwan E, Creagh AL, Kilburn DG, Haynes CA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jul 25;807(1):87-94.

PMID:
15177165
31.

Binding specificity and thermodynamics of a family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A.

Boraston AB, Creagh AL, Alam MM, Kormos JM, Tomme P, Haynes CA, Warren RA, Kilburn DG.

Biochemistry. 2001 May 29;40(21):6240-7.

PMID:
11371185
32.

Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex.

Luo Y, Frey EA, Pfuetzner RA, Creagh AL, Knoechel DG, Haynes CA, Finlay BB, Strynadka NC.

Nature. 2000 Jun 29;405(6790):1073-7.

PMID:
10890451
33.

Structure and binding specificity of the second N-terminal cellulose-binding domain from Cellulomonas fimi endoglucanase C.

Brun E, Johnson PE, Creagh AL, Tomme P, Webster P, Haynes CA, McIntosh LP.

Biochemistry. 2000 Mar 14;39(10):2445-58.

PMID:
10704194
34.

Characterization and affinity applications of cellulose-binding domains.

Tomme P, Boraston A, McLean B, Kormos J, Creagh AL, Sturch K, Gilkes NR, Haynes CA, Warren RA, Kilburn DG.

J Chromatogr B Biomed Sci Appl. 1998 Sep 11;715(1):283-96.

PMID:
9792516
35.

Calcium binding by the N-terminal cellulose-binding domain from Cellulomonas fimi beta-1,4-glucanase CenC.

Johnson PE, Creagh AL, Brun E, Joe K, Tomme P, Haynes CA, McIntosh LP.

Biochemistry. 1998 Sep 15;37(37):12772-81.

PMID:
9737854
36.

Stability and oligosaccharide binding of the N1 cellulose-binding domain of Cellulomonas fimi endoglucanase CenC.

Creagh AL, Koska J, Johnson PE, Tomme P, Joshi MD, McIntosh LP, Kilburn DG, Haynes CA.

Biochemistry. 1998 Mar 10;37(10):3529-37.

PMID:
9521674
37.

Thermostability and irreversible activity loss of exoglucanase/xylanase Cex from Cellulomonas fimi.

Nikolova PV, Creagh AL, Duff SJ, Haynes CA.

Biochemistry. 1997 Feb 11;36(6):1381-8.

PMID:
9063886
38.
39.

Binding of the cellulose-binding domain of exoglucanase Cex from Cellulomonas fimi to insoluble microcrystalline cellulose is entropically driven.

Creagh AL, Ong E, Jervis E, Kilburn DG, Haynes CA.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12229-34.

40.

The role of a conserved tyrosine residue in high-potential iron sulfur proteins.

Iwagami SG, Creagh AL, Haynes CA, Borsari M, Felli IC, Piccioli M, Eltis LD.

Protein Sci. 1995 Dec;4(12):2562-72.

41.

Separation of amino-acid enantiomers using Micellar-enhanced ultrafiltration.

Creagh AL, Hasenack BB, Van der Padt A, Sudhölter EJ, Van't Riet K.

Biotechnol Bioeng. 1995 Jan 5;45(1):95. No abstract available.

PMID:
18623057
42.

Separation of amino-acid enantiomers using micellar-enhanced ultrafiltration.

Creagh AL, Hasenack BB, Van der Padt A, Sudhölter EJ, Van't Riet K.

Biotechnol Bioeng. 1994 Sep 5;44(6):690-8.

PMID:
18618829
43.

Structural and catalytic properties of enzymes in reverse micelles.

Creagh AL, Prausnitz JM, Blanch HW.

Enzyme Microb Technol. 1993 May;15(5):383-92.

PMID:
7684231
44.

The effect of aqueous surfactant solutions on alcohol dehydrogenase (LADH).

Creagh AL, Prausnitz JM, Blanch HW.

Biotechnol Bioeng. 1993 Jan 5;41(1):156-61.

PMID:
18601257
45.

Mechanisms of protein solubilization in reverse micelles.

Matzke SF, Creagh AL, Haynes CA, Prausnitz JM, Blanch HW.

Biotechnol Bioeng. 1992 Jun 5;40(1):91-102.

PMID:
18601049

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