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Slowed Temporal and Parietal Cerebrovascular Response in patients with Alzheimer's Disease.

Holmes KR, Tang-Wai D, Sam K, McKetton L, Poublanc J, Crawley AP, Sobczyk O, Cohn M, Duffin J, Tartaglia MC, Black SE, Fisher JA, Wasserman B, Mikulis DJ.

Can J Neurol Sci. 2020 Feb 13:1-28. doi: 10.1017/cjn.2020.30. [Epub ahead of print] No abstract available.


In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism.

Gobeil Odai K, O'Dwyer C, Steenbergen R, Shaw TA, Renner TM, Ghorbani P, Rezaaifar M, Han S, Langlois MA, Crawley AM, Russell RS, Pezacki JP, Tyrrell DL, Fullerton MD.

Viruses. 2020 Jan 16;12(1). pii: E108. doi: 10.3390/v12010108.


Explorer les choix de cannabinoïdes pour la douleur neuropathique chronique chez les adultes plus âgés: Embûches et faits saillants.

Kamrul R, Bunka D, Crawley A, Schuster B, LeBras M.

Can Fam Physician. 2019 Nov;65(11):e469-e474. French. No abstract available.

Free PMC Article

Navigating cannabinoid choices for chronic neuropathic pain in older adults: Potholes and highlights.

Kamrul R, Bunka D, Crawley A, Schuster B, LeBras M.

Can Fam Physician. 2019 Nov;65(11):807-811. No abstract available.


Direct-Acting Antiviral Treatment of HCV Infection Does Not Resolve the Dysfunction of Circulating CD8+ T-Cells in Advanced Liver Disease.

Vranjkovic A, Deonarine F, Kaka S, Angel JB, Cooper CL, Crawley AM.

Front Immunol. 2019 Aug 13;10:1926. doi: 10.3389/fimmu.2019.01926. eCollection 2019.


Evaluation of Safety and Effectiveness of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Switch Followed by Ledipasvir/Sofosbuvir HCV Therapy in HIV-HCV Coinfection.

Doyle MA, Lee T, Singer J, Crawley A, Klein M, Cooper C.

Open Forum Infect Dis. 2019 Jul 1;6(7). pii: ofz318. doi: 10.1093/ofid/ofz318.


An Advanced Pharmacy Practice Experience for Community Pharmacies Based on a Clinical Intervention Targeting Patients With Inflammatory Bowel Disease.

Blackburn DF, Fowler S, Crawley A, Gerwing S, Alcorn J, Mansell H, Evans C, Mansell K, Taylor J, Jorgenson D, Larocque D, Rotter T, Shevchuk Y.

J Pharm Pract. 2019 Jun 25:897190019857410. doi: 10.1177/0897190019857410. [Epub ahead of print]


Epihack Sri Lanka: development of a mobile surveillance tool for dengue fever.

Lwin MO, Sheldenkar A, Panchapakesan C, Ng JS, Lau J, Jayasundar K, Horathalge K, Rathnayake VS, Crawley AW, Wimalaratne P.

BMC Med Inform Decis Mak. 2019 Jun 13;19(1):111. doi: 10.1186/s12911-019-0829-5.


The efficiency of the brain connectome is associated with cerebrovascular reactivity in persons with white matter hyperintensities.

Reginold W, Sam K, Poublanc J, Fisher J, Crawley A, Mikulis DJ.

Hum Brain Mapp. 2019 Aug 15;40(12):3647-3656. doi: 10.1002/hbm.24622. Epub 2019 May 21.


Cerebrovascular Resistance in Healthy Aging and Mild Cognitive Impairment.

McKetton L, Cohn M, Tang-Wai DF, Sobczyk O, Duffin J, Holmes KR, Poublanc J, Sam K, Crawley AP, Venkatraghavan L, Fisher JA, Mikulis DJ.

Front Aging Neurosci. 2019 Apr 12;11:79. doi: 10.3389/fnagi.2019.00079. eCollection 2019.


Chronic Hepatitis C Virus Infection Impairs M1 Macrophage Differentiation and Contributes to CD8+ T-Cell Dysfunction.

Ahmed F, Ibrahim A, Cooper CL, Kumar A, Crawley AM.

Cells. 2019 Apr 25;8(4). pii: E374. doi: 10.3390/cells8040374.


CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems.

Crawley AB, Henriksen JR, Barrangou R.

CRISPR J. 2018 Apr;1:171-181. doi: 10.1089/crispr.2017.0022. Epub 2018 Apr 9.


Hepatitis C Direct Acting Antivirals and Ribavirin Modify Lipid but not Glucose Parameters.

Doyle MA, Galanakis C, Mulvihill E, Crawley A, Cooper CL.

Cells. 2019 Mar 15;8(3). pii: E252. doi: 10.3390/cells8030252.


3-Tesla MRI of deep brain stimulation patients: safety assessment of coils and pulse sequences.

Boutet A, Hancu I, Saha U, Crawley A, Xu DS, Ranjan M, Hlasny E, Chen R, Foltz W, Sammartino F, Coblentz A, Kucharczyk W, Lozano AM.

J Neurosurg. 2019 Feb 22:1-9. doi: 10.3171/2018.11.JNS181338. [Epub ahead of print]


Improved White Matter Cerebrovascular Reactivity after Revascularization in Patients with Steno-Occlusive Disease.

McKetton L, Venkatraghavan L, Rosen C, Mandell DM, Sam K, Sobczyk O, Poublanc J, Gray E, Crawley A, Duffin J, Fisher JA, Mikulis DJ.

AJNR Am J Neuroradiol. 2019 Jan;40(1):45-50. doi: 10.3174/ajnr.A5912. Epub 2018 Dec 20.


Correction: Monitoring for myelopathic progression with multiparametric quantitative MRI.

Martin AR, De Leener B, Cohen-Adad J, Kalsi-Ryan S, Cadotte DW, Wilson JR, Tetreault L, Nouri A, Crawley A, Mikulis DJ, Ginsberg H, Massicotte EM, Fehlings MG.

PLoS One. 2018 Sep 12;13(9):e0204082. doi: 10.1371/journal.pone.0204082. eCollection 2018.


Neuropathic pain and pain interference are linked to alpha-band slowing and reduced beta-band magnetoencephalography activity within the dynamic pain connectome in patients with multiple sclerosis.

Kim JA, Bosma RL, Hemington KS, Rogachov A, Osborne NR, Cheng JC, Oh J, Crawley AP, Dunkley BT, Davis KD.

Pain. 2019 Jan;160(1):187-197. doi: 10.1097/j.pain.0000000000001391.


Conserved Genome Organization and Core Transcriptome of the Lactobacillus acidophilus Complex.

Crawley AB, Barrangou R.

Front Microbiol. 2018 Aug 13;9:1834. doi: 10.3389/fmicb.2018.01834. eCollection 2018.


Comparison of crowd-sourced, electronic health records based, and traditional health-care based influenza-tracking systems at multiple spatial resolutions in the United States of America.

Baltrusaitis K, Brownstein JS, Scarpino SV, Bakota E, Crawley AW, Conidi G, Gunn J, Gray J, Zink A, Santillana M.

BMC Infect Dis. 2018 Aug 15;18(1):403. doi: 10.1186/s12879-018-3322-3.


Sevrage des opioïdes à l’aide de l’entretien motivationnel.

Crawley A, Murphy L, Regier L, McKee N.

Can Fam Physician. 2018 Aug;64(8):e341-e345. French. No abstract available.

Free PMC Article

Tapering opioids using motivational interviewing.

Crawley A, Murphy L, Regier L, McKee N.

Can Fam Physician. 2018 Aug;64(8):584-587. No abstract available.


Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems.

Faure G, Shmakov SA, Makarova KS, Wolf YI, Crawley AB, Barrangou R, Koonin EV.

RNA Biol. 2019 Apr;16(4):435-448. doi: 10.1080/15476286.2018.1493331. Epub 2018 Aug 14.


Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli.

Crawley AB, Henriksen ED, Stout E, Brandt K, Barrangou R.

Sci Rep. 2018 Aug 1;8(1):11544. doi: 10.1038/s41598-018-29746-3.


Impact of white matter hyperintensities on surrounding white matter tracts.

Reginold W, Sam K, Poublanc J, Fisher J, Crawley A, Mikulis DJ.

Neuroradiology. 2018 Sep;60(9):933-944. doi: 10.1007/s00234-018-2053-x. Epub 2018 Jul 20.


Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri.

Stout EA, Sanozky-Dawes R, Goh YJ, Crawley AB, Klaenhammer TR, Barrangou R.

Microbiology. 2018 Sep;164(9):1098-1111. doi: 10.1099/mic.0.000689. Epub 2018 Jul 19.


The aging brain and cerebrovascular reactivity.

McKetton L, Sobczyk O, Duffin J, Poublanc J, Sam K, Crawley AP, Venkatraghavan L, Fisher JA, Mikulis DJ.

Neuroimage. 2018 Nov 1;181:132-141. doi: 10.1016/j.neuroimage.2018.07.007. Epub 2018 Jul 5.


Cerebrovascular Resistance: The Basis of Cerebrovascular Reactivity.

Duffin J, Sobczyk O, McKetton L, Crawley A, Poublanc J, Venkatraghavan L, Sam K, Mutch WA, Mikulis D, Fisher JA.

Front Neurosci. 2018 Jun 19;12:409. doi: 10.3389/fnins.2018.00409. eCollection 2018.


Long-term changes in cerebrovascular reactivity following EC-IC bypass for intracranial steno-occlusive disease.

Rosen C, McKetton L, Russell J, Sam K, Poublanc J, Crawley A, Han JS, Sobczyk O, Duffin J, Mandell DM, Tymianski M, Fisher JA, Mikulis DJ, Venkatraghavan L.

J Clin Neurosci. 2018 Aug;54:77-82. doi: 10.1016/j.jocn.2018.06.009. Epub 2018 Jun 12.


Developments in Point-of-Care Diagnostic Technology for Cancer Detection.

Hayes B, Murphy C, Crawley A, O'Kennedy R.

Diagnostics (Basel). 2018 Jun 2;8(2). pii: E39. doi: 10.3390/diagnostics8020039. Review.


The Neural Correlates of Self-Regulatory Fatigability During Inhibitory Control of Eye Blinking.

Abi-Jaoude E, Segura B, Cho SS, Crawley A, Sandor P.

J Neuropsychiatry Clin Neurosci. 2018 Fall;30(4):325-333. doi: 10.1176/appi.neuropsych.17070140. Epub 2018 May 30.


Importance of Collateralization in Patients With Large Artery Intracranial Occlusive Disease: Long-Term Longitudinal Assessment of Cerebral Hemodynamic Function.

McKetton L, Venkatraghavan L, Poublanc J, Sobczyk O, Crawley AP, Rosen C, Silver FL, Duffin J, Fisher JA, Mikulis DJ.

Front Neurol. 2018 Apr 6;9:226. doi: 10.3389/fneur.2018.00226. eCollection 2018.


Is Rest Really Rest? Resting-State Functional Connectivity During Rest and Motor Task Paradigms.

Jurkiewicz MT, Crawley AP, Mikulis DJ.

Brain Connect. 2018 Jun;8(5):268-275. doi: 10.1089/brain.2017.0495.


Monitoring for myelopathic progression with multiparametric quantitative MRI.

Martin AR, De Leener B, Cohen-Adad J, Kalsi-Ryan S, Cadotte DW, Wilson JR, Tetreault L, Nouri A, Crawley A, Mikulis DJ, Ginsberg H, Massicotte EM, Fehlings MG.

PLoS One. 2018 Apr 17;13(4):e0195733. doi: 10.1371/journal.pone.0195733. eCollection 2018. Erratum in: PLoS One. 2018 Sep 12;13(9):e0204082.


Can microstructural MRI detect subclinical tissue injury in subjects with asymptomatic cervical spinal cord compression? A prospective cohort study.

Martin AR, De Leener B, Cohen-Adad J, Cadotte DW, Nouri A, Wilson JR, Tetreault L, Crawley AP, Mikulis DJ, Ginsberg H, Fehlings MG.

BMJ Open. 2018 Apr 13;8(4):e019809. doi: 10.1136/bmjopen-2017-019809.


Hepatitis C virus core protein reduces CD8+ T-cell proliferation, perforin production and degranulation but increases STAT5 activation.

Khan ST, Karges W, Cooper CL, Crawley AM.

Immunology. 2018 May;154(1):156-165. doi: 10.1111/imm.12882. Epub 2018 Jan 25.


Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques.

Steele AK, Carrasco-Medina L, Sodora DL, Crawley AM.

PLoS One. 2017 Dec 19;12(12):e0188427. doi: 10.1371/journal.pone.0188427. eCollection 2017.


Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum.

Hidalgo-Cantabrana C, Crawley AB, Sanchez B, Barrangou R.

Front Microbiol. 2017 Sep 26;8:1851. doi: 10.3389/fmicb.2017.01851. eCollection 2017.


Participatory Disease Surveillance: Engaging Communities Directly in Reporting, Monitoring, and Responding to Health Threats.

Smolinski MS, Crawley AW, Olsen JM, Jayaraman T, Libel M.

JMIR Public Health Surveill. 2017 Oct 11;3(4):e62. doi: 10.2196/publichealth.7540.


The role of vascular resistance in BOLD responses to progressive hypercapnia.

Duffin J, Sobczyk O, Crawley A, Poublanc J, Venkatraghavan L, Sam K, Mutch A, Mikulis D, Fisher J.

Hum Brain Mapp. 2017 Nov;38(11):5590-5602. doi: 10.1002/hbm.23751. Epub 2017 Aug 7.


Transfer learning on fused multiparametric MR images for classifying histopathological subtypes of rhabdomyosarcoma.

Banerjee I, Crawley A, Bhethanabotla M, Daldrup-Link HE, Rubin DL.

Comput Med Imaging Graph. 2018 Apr;65:167-175. doi: 10.1016/j.compmedimag.2017.05.002. Epub 2017 May 5.


A mechanistic cohort study evaluating cognitive impairment in women treated for breast cancer.

Vardy JL, Stouten-Kemperman MM, Pond G, Booth CM, Rourke SB, Dhillon HM, Dodd A, Crawley A, Tannock IF.

Brain Imaging Behav. 2019 Feb;13(1):15-26. doi: 10.1007/s11682-017-9728-5.


Brain Resting-State Functional Connectivity Is Preserved Under Sevoflurane Anesthesia in Patients with Pervasive Developmental Disorders: A Pilot Study.

Venkatraghavan L, Bharadwaj S, Wourms V, Tan A, Jurkiewicz MT, Mikulis DJ, Crawley AP.

Brain Connect. 2017 May;7(4):250-257. doi: 10.1089/brain.2016.0448.


Clinically Feasible Microstructural MRI to Quantify Cervical Spinal Cord Tissue Injury Using DTI, MT, and T2*-Weighted Imaging: Assessment of Normative Data and Reliability.

Martin AR, De Leener B, Cohen-Adad J, Cadotte DW, Kalsi-Ryan S, Lange SF, Tetreault L, Nouri A, Crawley A, Mikulis DJ, Ginsberg H, Fehlings MG.

AJNR Am J Neuroradiol. 2017 Jun;38(6):1257-1265. doi: 10.3174/ajnr.A5163. Epub 2017 Apr 20.


A Novel MRI Biomarker of Spinal Cord White Matter Injury: T2*-Weighted White Matter to Gray Matter Signal Intensity Ratio.

Martin AR, De Leener B, Cohen-Adad J, Cadotte DW, Kalsi-Ryan S, Lange SF, Tetreault L, Nouri A, Crawley A, Mikulis DJ, Ginsberg H, Fehlings MG.

AJNR Am J Neuroradiol. 2017 Jun;38(6):1266-1273. doi: 10.3174/ajnr.A5162. Epub 2017 Apr 20.


Biosensors for the monitoring of harmful algal blooms.

McPartlin DA, Loftus JH, Crawley AS, Silke J, Murphy CS, O'Kennedy RJ.

Curr Opin Biotechnol. 2017 Jun;45:164-169. doi: 10.1016/j.copbio.2017.02.018. Review.


Determinants of Participants' Follow-Up and Characterization of Representativeness in Flu Near You, A Participatory Disease Surveillance System.

Baltrusaitis K, Santillana M, Crawley AW, Chunara R, Smolinski M, Brownstein JS.

JMIR Public Health Surveill. 2017 Apr 7;3(2):e18. doi: 10.2196/publichealth.7304.


Finding Outbreaks Faster.

Smolinski MS, Crawley AW, Olsen JM.

Health Secur. 2017 Mar/Apr;15(2):215-220. doi: 10.1089/hs.2016.0069. Epub 2017 Apr 6.


Assessing cerebrovascular reactivity by the pattern of response to progressive hypercapnia.

Fisher JA, Sobczyk O, Crawley A, Poublanc J, Dufort P, Venkatraghavan L, Sam K, Mikulis D, Duffin J.

Hum Brain Mapp. 2017 Jul;38(7):3415-3427. doi: 10.1002/hbm.23598. Epub 2017 Apr 3.


Invalidation of fMRI experiments secondary to neurovascular uncoupling in patients with cerebrovascular disease.

Para AE, Sam K, Poublanc J, Fisher JA, Crawley AP, Mikulis DJ.

J Magn Reson Imaging. 2017 Nov;46(5):1448-1455. doi: 10.1002/jmri.25639. Epub 2017 Feb 2.


Strategies for overcoming challenges for decentralised diagnostics in resource-limited and catastrophe settings.

Sharma S, Crawley A, O'Kennedy R.

Expert Rev Mol Diagn. 2017 Feb;17(2):109-118. doi: 10.1080/14737159.2017.1273773. Epub 2017 Jan 2. Review.


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