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Items: 32


The exercise cytokine interleukin-15 rescues slow wound healing in aged mice.

Wong W, Crane ED, Kuo Y, Kim A, Crane JD.

J Biol Chem. 2019 Dec 27;294(52):20024-20038. doi: 10.1074/jbc.RA119.010740. Epub 2019 Nov 20.


Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule.

Yabut JM, Crane JD, Green AE, Keating DJ, Khan WI, Steinberg GR.

Endocr Rev. 2019 Aug 1;40(4):1092-1107. doi: 10.1210/er.2018-00283. Review.


Optimizing the methodology for measuring supraclavicular skin temperature using infrared thermography; implications for measuring brown adipose tissue activity in humans.

Haq T, Crane JD, Kanji S, Gunn E, Tarnopolsky MA, Gerstein HC, Steinberg GR, Morrison KM.

Sci Rep. 2017 Sep 20;7(1):11934. doi: 10.1038/s41598-017-11537-x.


FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis.

Mottillo EP, Desjardins EM, Fritzen AM, Zou VZ, Crane JD, Yabut JM, Kiens B, Erion DM, Lanba A, Granneman JG, Talukdar S, Steinberg GR.

Mol Metab. 2017 Apr 5;6(6):471-481. doi: 10.1016/j.molmet.2017.04.001. eCollection 2017 Jun.


Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1.

Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR.

Diabetes. 2016 Nov;65(11):3352-3361. Epub 2016 Aug 23.


ELBW survivors in early adulthood have higher hepatic, pancreatic and subcutaneous fat.

Crane JD, Yellin SA, Ong FJ, Singh NP, Konyer N, Noseworthy MD, Schmidt LA, Saigal S, Morrison KM.

Sci Rep. 2016 Aug 17;6:31560. doi: 10.1038/srep31560.


Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function.

Mottillo EP, Desjardins EM, Crane JD, Smith BK, Green AE, Ducommun S, Henriksen TI, Rebalka IA, Razi A, Sakamoto K, Scheele C, Kemp BE, Hawke TJ, Ortega J, Granneman JG, Steinberg GR.

Cell Metab. 2016 Jul 12;24(1):118-29. doi: 10.1016/j.cmet.2016.06.006.


AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging.

Bujak AL, Crane JD, Lally JS, Ford RJ, Kang SJ, Rebalka IA, Green AE, Kemp BE, Hawke TJ, Schertzer JD, Steinberg GR.

Cell Metab. 2015 Jun 2;21(6):883-90. doi: 10.1016/j.cmet.2015.05.016.


Skeletal muscle AMPK is essential for the maintenance of FNDC5 expression.

Lally JS, Ford RJ, Johar J, Crane JD, Kemp BE, Steinberg GR.

Physiol Rep. 2015 May;3(5). pii: e12343. doi: 10.14814/phy2.12343.


Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging.

Crane JD, MacNeil LG, Lally JS, Ford RJ, Bujak AL, Brar IK, Kemp BE, Raha S, Steinberg GR, Tarnopolsky MA.

Aging Cell. 2015 Aug;14(4):625-34. doi: 10.1111/acel.12341. Epub 2015 Apr 22.


Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity.

Ford RJ, Fullerton MD, Pinkosky SL, Day EA, Scott JW, Oakhill JS, Bujak AL, Smith BK, Crane JD, Blümer RM, Marcinko K, Kemp BE, Gerstein HC, Steinberg GR.

Biochem J. 2015 May 15;468(1):125-32. doi: 10.1042/BJ20150125.


Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men.

Ogborn DI, McKay BR, Crane JD, Safdar A, Akhtar M, Parise G, Tarnopolsky MA.

Am J Physiol Regul Integr Comp Physiol. 2015 Apr 15;308(8):R734-41. doi: 10.1152/ajpregu.00005.2014. Epub 2015 Feb 18.


Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis.

Crane JD, Palanivel R, Mottillo EP, Bujak AL, Wang H, Ford RJ, Collins A, Blümer RM, Fullerton MD, Yabut JM, Kim JJ, Ghia JE, Hamza SM, Morrison KM, Schertzer JD, Dyck JR, Khan WI, Steinberg GR.

Nat Med. 2015 Feb;21(2):166-72. doi: 10.1038/nm.3766. Epub 2014 Dec 8.


Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice.

Kolesar JE, Safdar A, Abadi A, MacNeil LG, Crane JD, Tarnopolsky MA, Kaufman BA.

Free Radic Biol Med. 2014 Oct;75:241-51. doi: 10.1016/j.freeradbiomed.2014.07.038. Epub 2014 Aug 12.


The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.

Ogborn DI, McKay BR, Crane JD, Parise G, Tarnopolsky MA.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R664-9. doi: 10.1152/ajpregu.00511.2013. Epub 2014 Jul 9.


A standardized infrared imaging technique that specifically detects UCP1-mediated thermogenesis in vivo.

Crane JD, Mottillo EP, Farncombe TH, Morrison KM, Steinberg GR.

Mol Metab. 2014 Apr 21;3(4):490-4. doi: 10.1016/j.molmet.2014.04.007. eCollection 2014 Jul.


Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance.

Henriksbo BD, Lau TC, Cavallari JF, Denou E, Chi W, Lally JS, Crane JD, Duggan BM, Foley KP, Fullerton MD, Tarnopolsky MA, Steinberg GR, Schertzer JD.

Diabetes. 2014 Nov;63(11):3742-7. doi: 10.2337/db13-1398. Epub 2014 Jun 10.


Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle.

Crane JD, Abadi A, Hettinga BP, Ogborn DI, MacNeil LG, Steinberg GR, Tarnopolsky MA.

PLoS One. 2013 Dec 6;8(12):e81879. doi: 10.1371/journal.pone.0081879. eCollection 2013.


Amino acid infusion alters the expression of growth-related genes in multiple skeletal muscles.

Suer MK, Crane JD, Trappe TA, Jemiolo B, Trappe SW, Harber MP.

Aviat Space Environ Med. 2013 Jul;84(7):669-74.


Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice.

Abadi A, Crane JD, Ogborn D, Hettinga B, Akhtar M, Stokl A, Macneil L, Safdar A, Tarnopolsky M.

PLoS One. 2013;8(4):e60722. doi: 10.1371/journal.pone.0060722. Epub 2013 Apr 2.


Long-term aerobic exercise is associated with greater muscle strength throughout the life span.

Crane JD, Macneil LG, Tarnopolsky MA.

J Gerontol A Biol Sci Med Sci. 2013 Jun;68(6):631-8. doi: 10.1093/gerona/gls237. Epub 2012 Dec 3.


Effects of creatine and exercise on skeletal muscle of FRG1-transgenic mice.

Ogborn DI, Smith KJ, Crane JD, Safdar A, Hettinga BP, Tupler R, Tarnopolsky MA.

Can J Neurol Sci. 2012 Mar;39(2):225-31.


Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage.

Crane JD, Ogborn DI, Cupido C, Melov S, Hubbard A, Bourgeois JM, Tarnopolsky MA.

Sci Transl Med. 2012 Feb 1;4(119):119ra13. doi: 10.1126/scitranslmed.3002882.


AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.

O'Neill HM, Maarbjerg SJ, Crane JD, Jeppesen J, Jørgensen SB, Schertzer JD, Shyroka O, Kiens B, van Denderen BJ, Tarnopolsky MA, Kemp BE, Richter EA, Steinberg GR.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16092-7. doi: 10.1073/pnas.1105062108. Epub 2011 Sep 6.


Influence of tracer selection on protein synthesis rates at rest and postexercise in multiple human muscles.

Harber MP, Dickinson JM, Crane JD, Trappe SW, Trappe TA.

Metabolism. 2011 May;60(5):689-97. doi: 10.1016/j.metabol.2010.07.003. Epub 2010 Sep 6.


The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure.

Crane JD, Devries MC, Safdar A, Hamadeh MJ, Tarnopolsky MA.

J Gerontol A Biol Sci Med Sci. 2010 Feb;65(2):119-28. doi: 10.1093/gerona/glp179. Epub 2009 Dec 3.


Protein synthesis and the expression of growth-related genes are altered by running in human vastus lateralis and soleus muscles.

Harber MP, Crane JD, Dickinson JM, Jemiolo B, Raue U, Trappe TA, Trappe SW.

Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R708-14. doi: 10.1152/ajpregu.90906.2008. Epub 2008 Dec 31.


Resistance exercise reduces muscular substrates in women.

Harber MP, Crane JD, Douglass MD, Weindel KD, Trappe TA, Trappe SW, Fink WF.

Int J Sports Med. 2008 Sep;29(9):719-25. doi: 10.1055/s-2007-989442. Epub 2008 Jan 22.


Pediatric residents' telephone triage experience: do parents really follow telephone advice?

Crane JD, Benjamin JT.

Arch Pediatr Adolesc Med. 2000 Jan;154(1):71-4.


Veins of the upper cervical spinal cord in vertebral angiography.

Gabrielsen TO, Seeger JF, Crane JD.

Acta Radiol Diagn (Stockh). 1972;13(0):801-7. No abstract available.


Roentgenographic evaluation of traumatic rupture of the aorta.

Kirsh MM, Crane JD, Kahn DR, Gago O, Moores WY, Redman H, Bookstein JJ, Sloan H.

Surg Gynecol Obstet. 1970 Nov;131(5):900-4. No abstract available.


Repair of acute traumatic rupture of the aorta without extracorporeal circulation.

Kirsh MM, Kahn DR, Crane JD, Anastasia LF, Lui AH, Moores WY, Vathayanon S, Bookstein JJ, Sloan H.

Ann Thorac Surg. 1970 Sep;10(3):227-36. No abstract available.


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