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Items: 1 to 50 of 165

1.

Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Lung Adenocarcinoma (A549) Cells.

Sipos A, Kim KJ, Sioutas C, Crandall ED.

Int J Mol Sci. 2019 Oct 23;20(21). pii: E5253. doi: 10.3390/ijms20215253.

2.

Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1.

Little DR, Gerner-Mauro KN, Flodby P, Crandall ED, Borok Z, Akiyama H, Kimura S, Ostrin EJ, Chen J.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20545-20555. doi: 10.1073/pnas.1906663116. Epub 2019 Sep 23.

PMID:
31548395
3.

A coalescent sampler successfully detects biologically meaningful population structure overlooked by F-statistics.

Crandall ED, Toonen RJ; ToBo Laboratory, Selkoe KA.

Evol Appl. 2018 Oct 15;12(2):255-265. doi: 10.1111/eva.12712. eCollection 2019 Feb.

4.

CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro.

Luo J, Chimge NO, Zhou B, Flodby P, Castaldi A, Firth AL, Liu Y, Wang H, Yang C, Marconett CN, Crandall ED, Offringa IA, Frenkel B, Borok Z.

Int J Cancer. 2018 Dec 15;143(12):3169-3180. doi: 10.1002/ijc.31734. Epub 2018 Oct 16.

5.

Alveolar epithelial cell processing of nanoparticles activates autophagy and lysosomal exocytosis.

Sipos A, Kim KJ, Chow RH, Flodby P, Borok Z, Crandall ED.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L286-L300. doi: 10.1152/ajplung.00108.2018. Epub 2018 May 3.

6.

Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.

Zhou B, Flodby P, Luo J, Castillo DR, Liu Y, Yu FX, McConnell A, Varghese B, Li G, Chimge NO, Sunohara M, Koss MN, Elatre W, Conti P, Liebler JM, Yang C, Marconett CN, Laird-Offringa IA, Minoo P, Guan K, Stripp BR, Crandall ED, Borok Z.

J Clin Invest. 2018 Mar 1;128(3):970-984. doi: 10.1172/JCI90429. Epub 2018 Feb 5.

7.

Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.

Lax S, Rayes J, Wichaiyo S, Haining EJ, Lowe K, Grygielska B, Laloo R, Flodby P, Borok Z, Crandall ED, Thickett DR, Watson SP.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1016-L1029. doi: 10.1152/ajplung.00023.2017. Epub 2017 Aug 24.

8.

Oligopeptide Transport in Rat Lung Alveolar Epithelial Cells is Mediated by Pept2.

Gukasyan HJ, Uchiyama T, Kim KJ, Ehrhardt C, Wu SK, Borok Z, Crandall ED, Lee VHL.

Pharm Res. 2017 Dec;34(12):2488-2497. doi: 10.1007/s11095-017-2234-z. Epub 2017 Aug 22.

PMID:
28831683
9.

The Genomic Observatories Metadatabase (GeOMe): A new repository for field and sampling event metadata associated with genetic samples.

Deck J, Gaither MR, Ewing R, Bird CE, Davies N, Meyer C, Riginos C, Toonen RJ, Crandall ED.

PLoS Biol. 2017 Aug 3;15(8):e2002925. doi: 10.1371/journal.pbio.2002925. eCollection 2017 Aug.

10.

Astrocytic tight junctions control inflammatory CNS lesion pathogenesis.

Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw AT, Hara Y, Mariani JN, Sawai S, Flodby P, Crandall ED, Borok Z, Sofroniew MV, Chapouly C, John GR.

J Clin Invest. 2017 Aug 1;127(8):3136-3151. doi: 10.1172/JCI91301. Epub 2017 Jul 24.

11.

Cell-specific expression of aquaporin-5 (Aqp5) in alveolar epithelium is directed by GATA6/Sp1 via histone acetylation.

Flodby P, Li C, Liu Y, Wang H, Rieger ME, Minoo P, Crandall ED, Ann DK, Borok Z, Zhou B.

Sci Rep. 2017 Jun 14;7(1):3473. doi: 10.1038/s41598-017-03152-7.

12.

Navigating the currents of seascape genomics: how spatial analyses can augment population genomic studies.

Riginos C, Crandall ED, Liggins L, Bongaerts P, Treml EA.

Curr Zool. 2016 Dec;62(6):581-601. doi: 10.1093/cz/zow067. Epub 2016 Jul 6.

13.

Region-specific role for Pten in maintenance of epithelial phenotype and integrity.

Flodby P, Liebler JM, Sunohara M, Castillo DR, McConnell AM, Krishnaveni MS, Banfalvi A, Li M, Stripp B, Zhou B, Crandall ED, Minoo P, Borok Z.

Am J Physiol Lung Cell Mol Physiol. 2017 Jan 1;312(1):L131-L142. doi: 10.1152/ajplung.00005.2015. Epub 2016 Nov 18.

14.

IL-1R1-MyD88 axis elicits papain-induced lung inflammation.

Agoro R, Piotet-Morin J, Palomo J, Michaudel C, Vigne S, Maillet I, Chenuet P, Guillou N, Le Bérichel J, Kisielow M, Flodby P, Borok Z, Crandall ED, Le Bert M, Quesniaux V, Muller M, Di Padova F, Ryffel B, Gabay C, Couturier-Maillard A.

Eur J Immunol. 2016 Nov;46(11):2531-2541. doi: 10.1002/eji.201646366. Epub 2016 Sep 22.

15.

Cross-Species Transcriptome Profiling Identifies New Alveolar Epithelial Type I Cell-Specific Genes.

Marconett CN, Zhou B, Sunohara M, Pouldar TM, Wang H, Liu Y, Rieger ME, Tran E, Flodby P, Siegmund KD, Crandall ED, Laird-Offringa IA, Borok Z.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):310-321. doi: 10.1165/rcmb.2016-0071OC.

16.

Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance.

Flodby P, Kim YH, Beard LL, Gao D, Ji Y, Kage H, Liebler JM, Minoo P, Kim KJ, Borok Z, Crandall ED.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):395-406. doi: 10.1165/rcmb.2016-0005OC.

17.

p300/β-Catenin Interactions Regulate Adult Progenitor Cell Differentiation Downstream of WNT5a/Protein Kinase C (PKC).

Rieger ME, Zhou B, Solomon N, Sunohara M, Li C, Nguyen C, Liu Y, Pan JH, Minoo P, Crandall ED, Brody SL, Kahn M, Borok Z.

J Biol Chem. 2016 Mar 18;291(12):6569-82. doi: 10.1074/jbc.M115.706416. Epub 2016 Feb 1.

18.

Melting barriers to faunal exchange across ocean basins.

McKeon CS, Weber MX, Alter SE, Seavy NE, Crandall ED, Barshis DJ, Fechter-Leggett ED, Oleson KL.

Glob Chang Biol. 2016 Feb;22(2):465-73. doi: 10.1111/gcb.13116. Epub 2015 Nov 30.

PMID:
26618788
19.

Geo-Referenced, Abundance Calibrated Ocean Distribution of Chinook Salmon (Oncorhynchus tshawytscha) Stocks across the West Coast of North America.

Bellinger MR, Banks MA, Bates SJ, Crandall ED, Garza JC, Sylvia G, Lawson PW.

PLoS One. 2015 Jul 22;10(7):e0131276. doi: 10.1371/journal.pone.0131276. eCollection 2015.

20.

Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury.

Kage H, Flodby P, Gao D, Kim YH, Marconett CN, DeMaio L, Kim KJ, Crandall ED, Borok Z.

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L524-36. doi: 10.1152/ajplung.00077.2014. Epub 2014 Aug 8.

21.

Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis.

Li G, Flodby P, Luo J, Kage H, Sipos A, Gao D, Ji Y, Beard LL, Marconett CN, DeMaio L, Kim YH, Kim KJ, Laird-Offringa IA, Minoo P, Liebler JM, Zhou B, Crandall ED, Borok Z.

Am J Respir Cell Mol Biol. 2014 Aug;51(2):210-22. doi: 10.1165/rcmb.2013-0353OC.

22.

Polystyrene nanoparticle exposure induces ion-selective pores in lipid bilayers.

Negoda A, Kim KJ, Crandall ED, Worden RM.

Biochim Biophys Acta. 2013 Sep;1828(9):2215-22. doi: 10.1016/j.bbamem.2013.05.029. Epub 2013 Jun 5.

23.

Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium.

Xia T, Hamilton RF, Bonner JC, Crandall ED, Elder A, Fazlollahi F, Girtsman TA, Kim K, Mitra S, Ntim SA, Orr G, Tagmount M, Taylor AJ, Telesca D, Tolic A, Vulpe CD, Walker AJ, Wang X, Witzmann FA, Wu N, Xie Y, Zink JI, Nel A, Holian A.

Environ Health Perspect. 2013 Jun;121(6):683-90. doi: 10.1289/ehp.1306561. Epub 2013 May 6.

24.

Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms.

Fazlollahi F, Kim YH, Sipos A, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED.

Nanomedicine. 2013 Aug;9(6):786-94. doi: 10.1016/j.nano.2013.01.007. Epub 2013 Feb 20.

25.

Coalescent and biophysical models of stepping-stone gene flow in neritid snails.

Crandall ED, Treml EA, Barber PH.

Mol Ecol. 2012 Nov;21(22):5579-98. doi: 10.1111/mec.12031. Epub 2012 Oct 11.

PMID:
23050562
26.

Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.

Zhou B, Buckley ST, Patel V, Liu Y, Luo J, Krishnaveni MS, Ivan M, DeMaio L, Kim KJ, Ehrhardt C, Crandall ED, Borok Z.

PLoS One. 2012;7(6):e38827. doi: 10.1371/journal.pone.0038827. Epub 2012 Jun 20.

27.

Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).

Zhou B, Liu Y, Kahn M, Ann DK, Han A, Wang H, Nguyen C, Flodby P, Zhong Q, Krishnaveni MS, Liebler JM, Minoo P, Crandall ED, Borok Z.

J Biol Chem. 2012 Mar 2;287(10):7026-38. doi: 10.1074/jbc.M111.276311. Epub 2012 Jan 12.

28.

Translocation of PEGylated quantum dots across rat alveolar epithelial cell monolayers.

Fazlollahi F, Sipos A, Kim YH, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED.

Int J Nanomedicine. 2011;6:2849-57. doi: 10.2147/IJN.S26051. Epub 2011 Nov 10.

29.

Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.

DeMaio L, Buckley ST, Krishnaveni MS, Flodby P, Dubourd M, Banfalvi A, Xing Y, Ehrhardt C, Minoo P, Zhou B, Crandall ED, Borok Z.

J Pathol. 2012 Mar;226(4):633-44. doi: 10.1002/path.3016. Epub 2011 Dec 9.

30.

Expansion dating: calibrating molecular clocks in marine species from expansions onto the Sunda Shelf Following the Last Glacial Maximum.

Crandall ED, Sbrocco EJ, Deboer TS, Barber PH, Carpenter KE.

Mol Biol Evol. 2012 Feb;29(2):707-19. doi: 10.1093/molbev/msr227. Epub 2011 Sep 15. Erratum in: Mol Biol Evol. 2013 Oct;30(10):2366.

PMID:
21926069
31.

Nanomaterial interactions with and trafficking across the lung alveolar epithelial barrier: implications for health effects of air-pollution particles.

Yacobi NR, Fazllolahi F, Kim YH, Sipos A, Borok Z, Kim KJ, Crandall ED.

Air Qual Atmos Health. 2011 Mar 1;4(1):65-78.

32.

Polystyrene nanoparticle trafficking across MDCK-II.

Fazlollahi F, Angelow S, Yacobi NR, Marchelletta R, Yu AS, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED.

Nanomedicine. 2011 Oct;7(5):588-94. doi: 10.1016/j.nano.2011.01.008. Epub 2011 Feb 26.

33.

Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein.

Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, Banfalvi A, Krishnaveni MS, Dubourd M, Demaio L, Willis BC, Kim KJ, duBois RM, Crandall ED, Beers MF, Borok Z.

Am J Respir Cell Mol Biol. 2011 Sep;45(3):498-509. doi: 10.1165/rcmb.2010-0347OC. Epub 2010 Dec 17.

34.

Alveolar epithelial cell injury due to zinc oxide nanoparticle exposure.

Kim YH, Fazlollahi F, Kennedy IM, Yacobi NR, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED.

Am J Respir Crit Care Med. 2010 Dec 1;182(11):1398-409. doi: 10.1164/rccm.201002-0185OC. Epub 2010 Jul 16.

35.

High gene flow due to pelagic larval dispersal among South Pacific archipelagos in two amphidromous gastropods (Neritomorpha: Neritidae).

Crandall ED, Taffel JR, Barber PH.

Heredity (Edinb). 2010 Jun;104(6):563-72. doi: 10.1038/hdy.2009.138. Epub 2009 Oct 21.

36.

More life for a "terminal" cell.

Borok Z, Crandall ED.

Am J Physiol Lung Cell Mol Physiol. 2009 Dec;297(6):L1042-4. doi: 10.1152/ajplung.00355.2009. Epub 2009 Oct 16. No abstract available.

37.

Directed expression of Cre in alveolar epithelial type 1 cells.

Flodby P, Borok Z, Banfalvi A, Zhou B, Gao D, Minoo P, Ann DK, Morrisey EE, Crandall ED.

Am J Respir Cell Mol Biol. 2010 Aug;43(2):173-8. doi: 10.1165/rcmb.2009-0226OC. Epub 2009 Sep 18.

38.

Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles.

Yacobi NR, Malmstadt N, Fazlollahi F, DeMaio L, Marchelletta R, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED.

Am J Respir Cell Mol Biol. 2010 May;42(5):604-14. doi: 10.1165/rcmb.2009-0138OC. Epub 2009 Jul 2.

39.

Characterization of mouse alveolar epithelial cell monolayers.

Demaio L, Tseng W, Balverde Z, Alvarez JR, Kim KJ, Kelley DG, Senior RM, Crandall ED, Borok Z.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L1051-8. doi: 10.1152/ajplung.00021.2009. Epub 2009 Mar 27.

40.

Conjugation with cationic cell-penetrating peptide increases pulmonary absorption of insulin.

Patel LN, Wang J, Kim KJ, Borok Z, Crandall ED, Shen WC.

Mol Pharm. 2009 Mar-Apr;6(2):492-503. doi: 10.1021/mp800174g.

41.

Comparative phylogeography of two seastars and their ectosymbionts within the Coral Triangle.

Crandall ED, Jones ME, Muñoz MM, Akinronbi B, Erdmann MV, Barber PH.

Mol Ecol. 2008 Dec;17(24):5276-90. doi: 10.1111/j.1365-294X.2008.03995.x.

PMID:
19067797
42.

GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.

Zhou B, Francis TA, Yang H, Tseng W, Zhong Q, Frenkel B, Morrisey EE, Ann DK, Minoo P, Crandall ED, Borok Z.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1141-50. doi: 10.1152/ajpcell.00120.2008. Epub 2008 Sep 3.

43.

Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury.

Liebler JM, Lutzko C, Banfalvi A, Senadheera D, Aghamohammadi N, Crandall ED, Borok Z.

Am J Physiol Lung Cell Mol Physiol. 2008 Aug;295(2):L285-92. doi: 10.1152/ajplung.00222.2007. Epub 2008 May 30.

44.

Rat aquaporin-5 4.3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo.

Zhou B, Ann DK, Flodby P, Minoo P, Liebler JM, Crandall ED, Borok Z.

Am J Physiol Cell Physiol. 2008 Jul;295(1):C111-20. doi: 10.1152/ajpcell.90620.2007. Epub 2008 Apr 30.

45.

Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers.

Bahhady R, Kim KJ, Borok Z, Crandall ED, Shen WC.

Eur J Pharm Biopharm. 2008 Aug;69(3):808-16. doi: 10.1016/j.ejpb.2008.01.028. Epub 2008 Feb 6.

46.

Polystyrene nanoparticle trafficking across alveolar epithelium.

Yacobi NR, Demaio L, Xie J, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED.

Nanomedicine. 2008 Jun;4(2):139-45. doi: 10.1016/j.nano.2008.02.002. Epub 2008 Mar 28.

PMID:
18375191
47.

Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain.

Zhou B, Zhong Q, Minoo P, Li C, Ann DK, Frenkel B, Morrisey EE, Crandall ED, Borok Z.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):750-8. doi: 10.1165/rcmb.2007-0350OC. Epub 2008 Jan 31.

48.

Contrasting demographic history and phylogeographical patterns in two Indo-Pacific gastropods.

Crandall ED, Frey MA, Grosberg RK, Barber PH.

Mol Ecol. 2008 Jan;17(2):611-26. doi: 10.1111/j.1365-294X.2007.03600.x. Epub 2007 Dec 20.

PMID:
18179436
49.

Functional characterization and cloning of amino acid transporter B(0,+) (ATB(0,+)) in primary cultured rat pneumocytes.

Uchiyama T, Fujita T, Gukasyan HJ, Kim KJ, Borok Z, Crandall ED, Lee VH.

J Cell Physiol. 2008 Mar;214(3):645-54.

PMID:
17960566
50.

Expression and biological activity of ABCA1 in alveolar epithelial cells.

Bates SR, Tao JQ, Yu KJ, Borok Z, Crandall ED, Collins HL, Rothblat GH.

Am J Respir Cell Mol Biol. 2008 Mar;38(3):283-92. Epub 2007 Sep 20.

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