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Items: 1 to 50 of 199

1.

Genetic analysis of neurodegenerative diseases in a pathology cohort.

Blauwendraat C, Pletnikova O, Geiger JT, Murphy NA, Abramzon Y, Rudow G, Mamais A, Sabir MS, Crain B, Ahmed S, Rosenthal LS, Bakker CC, Faghri F, Chia R, Ding J, Dawson TM, Pantelyat A, Albert MS, Nalls MA, Resnick SM, Ferrucci L, Cookson MR, Hillis AE, Troncoso JC, Scholz SW.

Neurobiol Aging. 2019 Apr;76:214.e1-214.e9. doi: 10.1016/j.neurobiolaging.2018.11.007. Epub 2018 Nov 17.

PMID:
30528841
2.

The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype.

Pletnikova O, Kageyama Y, Rudow G, LaClair KD, Albert M, Crain BJ, Tian J, Fowler D, Troncoso JC.

Neurobiol Aging. 2018 Nov;71:72-80. doi: 10.1016/j.neurobiolaging.2018.07.007. Epub 2018 Jul 19.

PMID:
30099348
3.

Misdiagnosis of cerebellar hemorrhage - features of 'pseudo-gastroenteritis' clinical presentations to the ED and primary care.

Lee SH, Stanton V, Rothman RE, Crain B, Wityk R, Wang Z, Newman-Toker DE.

Diagnosis (Berl). 2017 Mar 1;4(1):27-33. doi: 10.1515/dx-2016-0038.

PMID:
29536910
4.

Frequency of Dermatologic Findings at Autopsy.

Cocks M, Sander I, Crain B.

J Forensic Sci. 2018 Nov;63(6):1867-1869. doi: 10.1111/1556-4029.13772. Epub 2018 Mar 8.

PMID:
29518291
5.

Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters.

Grunseich C, Wang IX, Watts JA, Burdick JT, Guber RD, Zhu Z, Bruzel A, Lanman T, Chen K, Schindler AB, Edwards N, Ray-Chaudhury A, Yao J, Lehky T, Piszczek G, Crain B, Fischbeck KH, Cheung VG.

Mol Cell. 2018 Feb 1;69(3):426-437.e7. doi: 10.1016/j.molcel.2017.12.030. Epub 2018 Jan 27.

6.

Alzheimer's disease pathology and shunt surgery outcome in normal pressure hydrocephalus.

Yasar S, Jusue-Torres I, Lu J, Robison J, Patel MA, Crain B, Carson KA, Hoffberger J, Batra S, Sankey E, Moghekar A, Rigamonti D.

PLoS One. 2017 Aug 7;12(8):e0182288. doi: 10.1371/journal.pone.0182288. eCollection 2017.

7.

Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice.

Goff PH, Hayashi T, He W, Yao S, Cottam HB, Tan GS, Crain B, Krammer F, Messer K, Pu M, Carson DA, Palese P, Corr M.

J Virol. 2017 Sep 12;91(19). pii: e01050-17. doi: 10.1128/JVI.01050-17. Print 2017 Oct 1.

8.

A Novel Experimental Animal Model of Adult Chronic Hydrocephalus.

Jusué-Torres I, Jeon LH, Sankey EW, Lu J, Vivas-Buitrago T, Crawford JA, Pletnikov MV, Xu J, Blitz A, Herzka DA, Crain B, Hulbert A, Guerrero-Cazares H, Gonzalez-Perez O, McAllister JP 2nd, Quiñones-Hinojosa A, Rigamonti D.

Neurosurgery. 2016 Nov;79(5):746-756.

PMID:
27759679
9.

Clinical Inferences of Cardiovascular Implantable Electronic Device Analysis at Autopsy.

Sinha SK, Crain B, Flickinger K, Calkins H, Rickard J, Cheng A, Berger R, Tomaselli G, Marine JE.

J Am Coll Cardiol. 2016 Sep 20;68(12):1255-64. doi: 10.1016/j.jacc.2016.06.052.

10.

From suspected Creutzfeldt-Jakob disease to confirmed histoplasma meningitis.

Batra V, Khararjian A, Wheat J, Zhang SX, Crain B, Baras A.

BMJ Case Rep. 2016 Jul 7;2016. pii: bcr2016214937. doi: 10.1136/bcr-2016-214937.

11.

Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies.

Geiger JT, Ding J, Crain B, Pletnikova O, Letson C, Dawson TM, Rosenthal LS, Pantelyat A, Gibbs JR, Albert MS, Hernandez DG, Hillis AE, Stone DJ, Singleton AB; North American Brain Expression Consortium, Hardy JA, Troncoso JC, Scholz SW.

Neurobiol Dis. 2016 Oct;94:55-62. doi: 10.1016/j.nbd.2016.06.004. Epub 2016 Jun 14.

12.

Cardiovascular implantable electronic device function and longevity at autopsy: an underestimated resource.

Sinha SK, Crain B, Flickinger K, Calkins H, Rickard J, Cheng A, Berger R, Tomaselli G, Marine JE.

Heart Rhythm. 2016 Oct;13(10):1971-6. doi: 10.1016/j.hrthm.2016.05.023. Epub 2016 May 27.

PMID:
27241351
13.

C9orf72 Hexanucleotide Repeat Analysis in Cases with Pathologically Confirmed Dementia with Lewy Bodies.

Geiger JT, Arthur KC, Dawson TM, Rosenthal LS, Pantelyat A, Albert M, Hillis AE, Crain B, Pletnikova O, Troncoso JC, Scholz SW.

Neurodegener Dis. 2016;16(5-6):370-2. doi: 10.1159/000445872. Epub 2016 May 31.

14.

Mutational Profiling Can Establish Clonal or Independent Origin in Synchronous Bilateral Breast and Other Tumors.

Bao L, Messer K, Schwab R, Harismendy O, Pu M, Crain B, Yost S, Frazer KA, Rana B, Hasteh F, Wallace A, Parker BA.

PLoS One. 2015 Nov 10;10(11):e0142487. doi: 10.1371/journal.pone.0142487. eCollection 2015.

15.

Alzheimer Lesions in the Autopsied Brains of People 30 to 50 Years of Age.

Pletnikova O, Rudow GL, Hyde TM, Kleinman JE, Ali SZ, Bharadwaj R, Gangadeen S, Crain BJ, Fowler DR, Rubio AI, Troncoso JC.

Cogn Behav Neurol. 2015 Sep;28(3):144-52. doi: 10.1097/WNN.0000000000000071.

16.

A window-of-opportunity biomarker study of etodolac in resectable breast cancer.

Schwab RB, Kato S, Crain B, Pu M, Messer K, Weidner N, Blair SL, Wallace AM, Carson DA, Parker BA.

Cancer Med. 2015 Oct;4(10):1583-8. doi: 10.1002/cam4.512. Epub 2015 Aug 15.

17.

Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides.

Shinchi H, Crain B, Yao S, Chan M, Zhang SS, Ahmadiiveli A, Suda Y, Hayashi T, Cottam HB, Carson DA.

Bioconjug Chem. 2015 Aug 19;26(8):1713-23. doi: 10.1021/acs.bioconjchem.5b00285. Epub 2015 Aug 5.

PMID:
26193334
18.

Cardiovascular pathologies in mucopolysaccharidosis type VII (Sly Syndrome).

Gniadek TJ, Singer N, Barker NJ, Spevak PJ, Crain BJ, Valle D, Halushka MK.

Cardiovasc Pathol. 2015 Sep-Oct;24(5):322-6. doi: 10.1016/j.carpath.2015.06.001. Epub 2015 Jun 19.

PMID:
26141114
19.

Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes.

Hayashi T, Yao S, Crain B, Promessi VJ, Shyu L, Sheng C, Kang M, Cottam HB, Carson DA, Corr M.

PLoS One. 2015 Jun 15;10(6):e0129867. doi: 10.1371/journal.pone.0129867. eCollection 2015.

20.

Detection and phasing of single base de novo mutations in biopsies from human in vitro fertilized embryos by advanced whole-genome sequencing.

Peters BA, Kermani BG, Alferov O, Agarwal MR, McElwain MA, Gulbahce N, Hayden DM, Tang YT, Zhang RY, Tearle R, Crain B, Prates R, Berkeley A, Munné S, Drmanac R.

Genome Res. 2015 Mar;25(3):426-34. doi: 10.1101/gr.181255.114. Epub 2015 Feb 11.

21.

Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses.

Goff PH, Hayashi T, Martínez-Gil L, Corr M, Crain B, Yao S, Cottam HB, Chan M, Ramos I, Eggink D, Heshmati M, Krammer F, Messer K, Pu M, Fernandez-Sesma A, Palese P, Carson DA.

J Virol. 2015 Mar;89(6):3221-35. doi: 10.1128/JVI.03337-14. Epub 2015 Jan 7.

22.

Hypoxic-ischemic encephalopathy mimicking acute necrotizing encephalopathy.

Wang KY, Singer HS, Crain B, Gujar S, Lin DD.

Pediatr Neurol. 2015 Jan;52(1):110-4. doi: 10.1016/j.pediatrneurol.2014.09.009. Epub 2014 Sep 22.

PMID:
25447929
23.

Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands.

Nour A, Hayashi T, Chan M, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Ahmadiiveli A, Messer K, Pu M, Corr M, Carson DA, Cottam HB.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):4931-8. doi: 10.1016/j.bmcl.2014.09.039. Epub 2014 Sep 22.

24.

63-year-old woman with dysphonia, dysphagia, and sleep apnea.

Andrikopoulou E, Ellis CL, Crain BJ.

Brain Pathol. 2014 Jul;24(4):423-4. No abstract available. Erratum in: Brain Pathol. 2015 Jan;25(1):120. Andrilopoulou, Efstathia [corrected to Andrikopoulou, Efstathia].

PMID:
25083539
25.

Initial diagnoses of patients ultimately diagnosed with prion disease.

Appleby BS, Rincon-Beardsley TD, Appleby KK, Crain BJ, Wallin MT.

J Alzheimers Dis. 2014;42(3):833-9. doi: 10.3233/JAD-132465.

PMID:
24934543
26.

Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation.

Hayashi T, Crain B, Yao S, Caneda CD, Cottam HB, Chan M, Corr M, Carson DA.

J Pharmacol Exp Ther. 2014 Aug;350(2):330-40. doi: 10.1124/jpet.114.214312. Epub 2014 Jun 3.

27.

Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion.

Pletnikova O, Sloane KL, Renton AE, Traynor BJ, Crain BJ, Reid T, Zu T, Ranum LP, Troncoso JC, Rabins PV, Onyike CU.

Neurobiol Aging. 2014 Oct;35(10):2419.e17-21. doi: 10.1016/j.neurobiolaging.2014.04.009. Epub 2014 Apr 18.

28.

Mild cognitive impairment and asymptomatic Alzheimer disease subjects: equivalent β-amyloid and tau loads with divergent cognitive outcomes.

Iacono D, Resnick SM, O'Brien R, Zonderman AB, An Y, Pletnikova O, Rudow G, Crain B, Troncoso JC.

J Neuropathol Exp Neurol. 2014 Apr;73(4):295-304. doi: 10.1097/NEN.0000000000000052.

29.

Inhibition of keratinocyte proliferation by phospholipid-conjugates of a TLR7 ligand in a Myc-induced hyperplastic actinic keratosis model in the absence of systemic side effects.

Crain B, Yao S, Keophilaone V, Promessi V, Kang M, Barberis A, Maj R, Mura E, Passini N, Holldack J, Ochoa R, Cottam HB, Carson DA, Hayashi T.

Eur J Dermatol. 2013 Sep-Oct;23(5):618-28. doi: 10.1684/ejd.2013.2155.

30.

Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand.

Wu CC, Crain B, Yao S, Sabet M, Lao FS, Tawatao RI, Chan M, Smee DF, Julander JG, Cottam HB, Guiney DG, Corr M, Carson DA, Hayashi T.

J Innate Immun. 2014;6(3):315-24. doi: 10.1159/000355217. Epub 2013 Nov 1.

31.

Dorsolumbosacral agenesis, nonterminal myelocystocele and secondary tonsillar herniation: prenatal and postnatal MRI evaluation and pathological correlation.

Bosemani T, Crain BJ, Huisman TA, Northington FJ, Tekes A.

Pediatr Neurosurg. 2013;49(1):38-42. doi: 10.1159/000355120. Epub 2013 Sep 26.

PMID:
24080601
32.

Identification of substituted pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands.

Chan M, Hayashi T, Mathewson RD, Nour A, Hayashi Y, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Messer K, Pu M, Corr M, Carson DA, Cottam HB.

J Med Chem. 2013 Jun 13;56(11):4206-23. doi: 10.1021/jm301694x. Epub 2013 May 24.

33.

Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer.

Barrett CL, Schwab RB, Jung H, Crain B, Goff DJ, Jamieson CH, Thistlethwaite PA, Harismendy O, Carson DA, Frazer KA.

PLoS One. 2013;8(3):e58714. doi: 10.1371/journal.pone.0058714. Epub 2013 Mar 20.

34.

Feasibility of creating a high-resolution 3D diffusion tensor imaging based atlas of the human brainstem: a case study at 11.7 T.

Aggarwal M, Zhang J, Pletnikova O, Crain B, Troncoso J, Mori S.

Neuroimage. 2013 Jul 1;74:117-27. doi: 10.1016/j.neuroimage.2013.01.061. Epub 2013 Feb 4.

35.

Improved protein extraction and protein identification from archival formalin-fixed paraffin-embedded human aortas.

Fu Z, Yan K, Rosenberg A, Jin Z, Crain B, Athas G, Heide RS, Howard T, Everett AD, Herrington D, Van Eyk JE.

Proteomics Clin Appl. 2013 Apr;7(3-4):217-24. doi: 10.1002/prca.201200064.

36.

Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system.

Hayashi T, Yao S, Crain B, Chan M, Tawatao RI, Gray C, Vuong L, Lao F, Cottam HB, Carson DA, Corr M.

PLoS One. 2012;7(9):e45860. doi: 10.1371/journal.pone.0045860. Epub 2012 Sep 28.

37.

Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.

Guo Z, Rudow G, Pletnikova O, Codispoti KE, Orr BA, Crain BJ, Duan W, Margolis RL, Rosenblatt A, Ross CA, Troncoso JC.

Mov Disord. 2012 Sep 15;27(11):1379-86. doi: 10.1002/mds.25159. Epub 2012 Sep 13.

38.

Longitudinal brain activity changes in asymptomatic Alzheimer disease.

Codispoti KE, Beason-Held LL, Kraut MA, O'Brien RJ, Rudow G, Pletnikova O, Crain B, Troncoso JC, Resnick SM.

Brain Behav. 2012 May;2(3):221-30. doi: 10.1002/brb3.47.

39.

Mast cell-mediated inhibition of abdominal neutrophil inflammation by a PEGylated TLR7 ligand.

Hayashi T, Yao S, Crain B, Chan M, Cottam HB, Lao F, Carson DA, Corr M.

Mediators Inflamm. 2012;2012:262394. doi: 10.1155/2012/262394. Epub 2011 Nov 17.

40.

Coexisting adult polyglucosan body disease with frontotemporal lobar degeneration with transactivation response DNA-binding protein-43 (TDP-43)-positive neuronal inclusions.

Farmer JG, Crain BJ, Harris BT, Turner RS.

Neurocase. 2013;19(1):67-75. doi: 10.1080/13554794.2011.654217. Epub 2012 Apr 16.

41.

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.

Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kövari E, Kukull WA, Leverenz JB, Love S, Mackenzie IR, Mann DM, Masliah E, McKee AC, Montine TJ, Morris JC, Schneider JA, Sonnen JA, Thal DR, Trojanowski JQ, Troncoso JC, Wisniewski T, Woltjer RL, Beach TG.

J Neuropathol Exp Neurol. 2012 May;71(5):362-81. doi: 10.1097/NEN.0b013e31825018f7. Review.

42.

Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1.

Norton JT, Hayashi T, Crain B, Cho JS, Miller LS, Corr M, Carson DA.

J Immunol. 2012 Apr 1;188(7):2977-80. doi: 10.4049/jimmunol.1100830. Epub 2012 Mar 2.

43.

Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing.

Harismendy O, Schwab RB, Bao L, Olson J, Rozenzhak S, Kotsopoulos SK, Pond S, Crain B, Chee MS, Messer K, Link DR, Frazer KA.

Genome Biol. 2011 Dec 20;12(12):R124. doi: 10.1186/gb-2011-12-12-r124.

44.

Permanent Genetic Resources added to Molecular Ecology Resources Database 1 April 2011-31 May 2011.

Molecular Ecology Resources Primer Development Consortium, Bonizzoni M, Bourjea J, Chen B, Crain BJ, Cui L, Fiorentino V, Hartmann S, Hendricks S, Ketmaier V, Ma X, Muths D, Pavesi L, Pfautsch S, Rieger MA, Santonastaso T, Sattabongkot J, Taron CH, Taron DJ, Tiedemann R, Yan G, Zheng B, Zhong D.

Mol Ecol Resour. 2011 Sep;11(5):935-6. doi: 10.1111/j.1755-0998.2011.03046.x. Epub 2011 Jul 20.

45.

Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates.

Norton JT, Hayashi T, Crain B, Corr M, Carson DA.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11163-8. doi: 10.1073/pnas.1107899108. Epub 2011 Jun 20.

46.

Plasma glial fibrillary acidic protein levels in children with sickle cell disease.

Savage WJ, Barron-Casella E, Fu Z, Dulloor P, Williams L, Crain BJ, White DA, Jennings JM, Van Eyk JE, Debaun MR, Everett A, Casella JF.

Am J Hematol. 2011 May;86(5):427-9. doi: 10.1002/ajh.21995.

47.

A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization.

Koliatsos VE, Cernak I, Xu L, Song Y, Savonenko A, Crain BJ, Eberhart CG, Frangakis CE, Melnikova T, Kim H, Lee D.

J Neuropathol Exp Neurol. 2011 May;70(5):399-416. doi: 10.1097/NEN.0b013e3182189f06.

PMID:
21487304
48.

JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis.

Guma M, Kashiwakura J, Crain B, Kawakami Y, Beutler B, Firestein GS, Kawakami T, Karin M, Corr M.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22122-7. doi: 10.1073/pnas.1016401107. Epub 2010 Dec 6.

49.

Co-existence of Parkinson's disease and progressive supranuclear palsy: case report and a review of the literature.

Abhinav K, Marsh L, Crain B, Reich SG, Biglan K.

Neurol Sci. 2011 Feb;32(1):159-63. doi: 10.1007/s10072-010-0386-2. Epub 2010 Aug 25. Review.

PMID:
20737180
50.

Atherosclerosis, dementia, and Alzheimer disease in the Baltimore Longitudinal Study of Aging cohort.

Dolan H, Crain B, Troncoso J, Resnick SM, Zonderman AB, Obrien RJ.

Ann Neurol. 2010 Aug;68(2):231-40. doi: 10.1002/ana.22055.

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