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Items: 37


Histologic Subtype Defines the Risk and Kinetics of Recurrence and Death for Primary Extremity/Truncal Liposarcoma.

Bartlett EK, Curtin CE, Seier K, Qin LX, Hameed M, Yoon SS, Crago AM, Brennan MF, Singer S.

Ann Surg. 2019 Jul 5. doi: 10.1097/SLA.0000000000003453. [Epub ahead of print]


Outcome of 1000 Patients With Gastrointestinal Stromal Tumor (GIST) Treated by Surgery in the Pre and Post-imatinib Eras.

Cavnar MJ, Seier K, Curtin C, Balachandran VP, Coit DG, Yoon SS, Crago AM, Strong VE, Tap WD, Gönen M, Antonescu CR, Brennan MF, Singer S, DeMatteo RP.

Ann Surg. 2019 Apr 2. doi: 10.1097/SLA.0000000000003277. [Epub ahead of print]


Yield of Colonoscopy in Identification of Newly Diagnosed Desmoid-Type Fibromatosis with Underlying Familial Adenomatous Polyposis.

van Houdt WJ, Wei IH, Kuk D, Qin LX, Jadeja B, Villano A, Hameed M, Singer S, Crago AM.

Ann Surg Oncol. 2019 Mar;26(3):765-771. doi: 10.1245/s10434-018-07138-1. Epub 2019 Jan 4.


Association of MRI T2 Signal Intensity With Desmoid Tumor Progression During Active Observation: A Retrospective Cohort Study.

Cassidy MR, Lefkowitz RA, Long N, Qin LX, Kirane A, Sbaity E, Hameed M, Coit DG, Brennan MF, Singer S, Crago AM.

Ann Surg. 2018 Nov 9. doi: 10.1097/SLA.0000000000003073. [Epub ahead of print]


The association of renal cell carcinoma with gastrointestinal stromal tumors.

Mendonca SJ, Sanchez A, Blum KA, Ghanaat M, Kashan MY, Benfante N, Russo P, Coleman JA, Crago AM, Hakimi AA.

J Surg Oncol. 2018 Jun;117(8):1716-1720. doi: 10.1002/jso.25080. Epub 2018 Jun 7.


PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence.

Klein ME, Dickson MA, Antonescu C, Qin LX, Dooley SJ, Barlas A, Manova K, Schwartz GK, Crago AM, Singer S, Koff A, Tap WD.

Oncogene. 2018 Sep;37(37):5066-5078. doi: 10.1038/s41388-018-0332-y. Epub 2018 May 23.


ATRX is a regulator of therapy induced senescence in human cells.

Kovatcheva M, Liao W, Klein ME, Robine N, Geiger H, Crago AM, Dickson MA, Tap WD, Singer S, Koff A.

Nat Commun. 2017 Aug 30;8(1):386. doi: 10.1038/s41467-017-00540-5.


Hedgehog Signaling Inhibitors Fail to Reduce Merkel Cell Carcinoma Viability.

Carroll TM, Williams JS, Daily K, Rogers T, Gelb T, Coxon A, Wang SQ, Crago AM, Busam KJ, Brownell I.

J Invest Dermatol. 2017 May;137(5):1187-1190. doi: 10.1016/j.jid.2017.01.008. Epub 2017 Jan 25. No abstract available.


Liposarcoma: Multimodality Management and Future Targeted Therapies.

Crago AM, Dickson MA.

Surg Oncol Clin N Am. 2016 Oct;25(4):761-73. doi: 10.1016/j.soc.2016.05.007. Epub 2016 Jul 30. Review.


Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma.

Okada T, Lee AY, Qin LX, Agaram N, Mimae T, Shen Y, O'Connor R, López-Lago MA, Craig A, Miller ML, Agius P, Molinelli E, Socci ND, Crago AM, Shima F, Sander C, Singer S.

Cancer Discov. 2016 Oct;6(10):1148-1165. Epub 2016 Aug 30.


Multimodality Management of Soft Tissue Tumors in the Extremity.

Crago AM, Lee AY.

Surg Clin North Am. 2016 Oct;96(5):977-92. doi: 10.1016/j.suc.2016.05.001. Review.


Overall Survival and Response to Systemic Therapy in Metastatic Extrauterine Leiomyosarcoma.

Shoushtari AN, Landa J, Kuk D, Sanchez A, Lala B, Schmidt N, Okoli C, Chi P, Dickson MA, Gounder MM, Keohan ML, Crago AM, Tap WD, D'Angelo SP.

Sarcoma. 2016;2016:3547497. doi: 10.1155/2016/3547497. Epub 2016 May 29.


Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial.

Dickson MA, Schwartz GK, Keohan ML, D'Angelo SP, Gounder MM, Chi P, Antonescu CR, Landa J, Qin LX, Crago AM, Singer S, Koff A, Tap WD.

JAMA Oncol. 2016 Jul 1;2(7):937-40. doi: 10.1001/jamaoncol.2016.0264.


The importance of surgical margins in retroperitoneal sarcoma.

Kirane A, Crago AM.

J Surg Oncol. 2016 Mar;113(3):270-6. doi: 10.1002/jso.24135. Epub 2015 Dec 28. Review.


A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas.

Munhoz RR, D'Angelo SP, Gounder MM, Keohan ML, Chi P, Carvajal RD, Singer S, Crago AM, Landa J, Healey JH, Qin LX, Hameed M, Ezeoke MO, Singh AS, Agulnik M, Chmielowski B, Luke JJ, Van Tine BA, Schwartz GK, Tap WD, Dickson MA.

Oncologist. 2015 Nov;20(11):1245-6. doi: 10.1634/theoncologist.2015-0245. Epub 2015 Oct 8.


Principles in Management of Soft Tissue Sarcoma.

Crago AM, Brennan MF.

Adv Surg. 2015;49:107-22. doi: 10.1016/j.yasu.2015.04.002. Epub 2015 May 5. Review. No abstract available.


Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis.

Crago AM, Chmielecki J, Rosenberg M, O'Connor R, Byrne C, Wilder FG, Thorn K, Agius P, Kuk D, Socci ND, Qin LX, Meyerson M, Hameed M, Singer S.

Genes Chromosomes Cancer. 2015 Oct;54(10):606-15. doi: 10.1002/gcc.22272. Epub 2015 Jul 14.


Outcomes of Systemic Therapy for Patients with Metastatic Angiosarcoma.

D'Angelo SP, Munhoz RR, Kuk D, Landa J, Hartley EW, Bonafede M, Dickson MA, Gounder M, Keohan ML, Crago AM, Antonescu CR, Tap WD.

Oncology. 2015;89(4):205-14. doi: 10.1159/000381917. Epub 2015 Jun 3.


Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma.

Tan MC, Brennan MF, Kuk D, Agaram NP, Antonescu CR, Qin LX, Moraco N, Crago AM, Singer S.

Ann Surg. 2016 Mar;263(3):593-600. doi: 10.1097/SLA.0000000000001149.


MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.

Kovatcheva M, Liu DD, Dickson MA, Klein ME, O'Connor R, Wilder FO, Socci ND, Tap WD, Schwartz GK, Singer S, Crago AM, Koff A.

Oncotarget. 2015 Apr 10;6(10):8226-43.


Soft tissue tumors of the trunk: management of local disease in the breast and chest and abdominal walls.

Wilder F, D'Angelo S, Crago AM.

J Surg Oncol. 2015 Apr;111(5):546-52. doi: 10.1002/jso.23843. Epub 2014 Nov 23. Review.


Extended surgical resection and histology in retroperitoneal sarcoma.

Crago AM.

Ann Surg Oncol. 2015 May;22(5):1401-3. doi: 10.1245/s10434-014-4135-2. Epub 2014 Oct 15. No abstract available.


Comparison of local recurrence with conventional and intensity-modulated radiation therapy for primary soft-tissue sarcomas of the extremity.

Folkert MR, Singer S, Brennan MF, Kuk D, Qin LX, Kobayashi WK, Crago AM, Alektiar KM.

J Clin Oncol. 2014 Oct 10;32(29):3236-41. doi: 10.1200/JCO.2013.53.9452. Epub 2014 Sep 2.


Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.

Miller ML, Molinelli EJ, Nair JS, Sheikh T, Samy R, Jing X, He Q, Korkut A, Crago AM, Singer S, Schwartz GK, Sander C.

Sci Signal. 2013 Sep 24;6(294):ra85. doi: 10.1126/scisignal.2004014.


Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.

Dickson MA, Tap WD, Keohan ML, D'Angelo SP, Gounder MM, Antonescu CR, Landa J, Qin LX, Rathbone DD, Condy MM, Ustoyev Y, Crago AM, Singer S, Schwartz GK.

J Clin Oncol. 2013 Jun 1;31(16):2024-8. doi: 10.1200/JCO.2012.46.5476. Epub 2013 Apr 8.


A prognostic nomogram for prediction of recurrence in desmoid fibromatosis.

Crago AM, Denton B, Salas S, Dufresne A, Mezhir JJ, Hameed M, Gonen M, Singer S, Brennan MF.

Ann Surg. 2013 Aug;258(2):347-53. doi: 10.1097/SLA.0b013e31828c8a30.


Desmoid fibromatosis in children and adolescents: a conservative approach to management.

Honeyman JN, Theilen TM, Knowles MA, McGlynn MM, Hameed M, Meyers P, Crago AM, La Quaglia MP.

J Pediatr Surg. 2013 Jan;48(1):62-6. doi: 10.1016/j.jpedsurg.2012.10.017.


Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors.

Chmielecki J, Crago AM, Rosenberg M, O'Connor R, Walker SR, Ambrogio L, Auclair D, McKenna A, Heinrich MC, Frank DA, Meyerson M.

Nat Genet. 2013 Feb;45(2):131-2. doi: 10.1038/ng.2522. Epub 2013 Jan 13.


Oncologic outcomes of sporadic, neurofibromatosis-associated, and radiation-induced malignant peripheral nerve sheath tumors.

LaFemina J, Qin LX, Moraco NH, Antonescu CR, Fields RC, Crago AM, Brennan MF, Singer S.

Ann Surg Oncol. 2013 Jan;20(1):66-72. doi: 10.1245/s10434-012-2573-2. Epub 2012 Aug 10.


The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification.

Italiano A, Thomas R, Breen M, Zhang L, Crago AM, Singer S, Khanin R, Maki RG, Mihailovic A, Hafner M, Tuschl T, Antonescu CR.

Genes Chromosomes Cancer. 2012 Jun;51(6):569-78. doi: 10.1002/gcc.21943. Epub 2012 Mar 2.


Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability.

Crago AM, Socci ND, DeCarolis P, O'Connor R, Taylor BS, Qin LX, Antonescu CR, Singer S.

Clin Cancer Res. 2012 Mar 1;18(5):1334-40. doi: 10.1158/1078-0432.CCR-11-2820. Epub 2012 Jan 12.


Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma.

Crago AM, Singer S.

Curr Opin Oncol. 2011 Jul;23(4):373-8. doi: 10.1097/CCO.0b013e32834796e6. Review.


Randomized clinical trials in breast cancer.

Crago AM, Azu M, Tierney S, Morrow M.

Surg Oncol Clin N Am. 2010 Jan;19(1):33-58. doi: 10.1016/j.soc.2009.09.003. Review.


Endovascular repair of a common iliac artery aneurysm using the Cook Zenith abdominal aortic aneurysm Endovascular Graft Converter.

Crago AM, Singh N, Deaton DH, Neville RF, Laredo J.

Vasc Endovascular Surg. 2008 Feb-Mar;42(1):54-7. doi: 10.1177/1538574407309317.


Monocyte chemoattractant activity of Ser195-->Ala active site mutant recombinant alpha-thrombin.

Crago AM, Wu HF, Hoffman M, Church FC.

Exp Cell Res. 1995 Aug;219(2):650-6.


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