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Items: 6

1.

Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition.

Kharasch ED, Crafford A.

Clin Pharmacol Ther. 2019 Jan;105(1):142-152. doi: 10.1002/cpt.1116. Epub 2018 Aug 9.

PMID:
29756345
2.

Influence of HIV antiretrovirals on methadone N-demethylation and transport.

Campbell SD, Gadel S, Friedel C, Crafford A, Regina KJ, Kharasch ED.

Biochem Pharmacol. 2015 May 15;95(2):115-25. doi: 10.1016/j.bcp.2015.03.007. Epub 2015 Mar 20.

PMID:
25801005
3.

Mechanism of autoinduction of methadone N-demethylation in human hepatocytes.

Campbell SD, Crafford A, Williamson BL, Kharasch ED.

Anesth Analg. 2013 Jul;117(1):52-60. doi: 10.1213/ANE.0b013e3182918252. Epub 2013 Jun 3.

4.

Methadone N-demethylation by the common CYP2B6 allelic variant CYP2B6.6.

Gadel S, Crafford A, Regina K, Kharasch ED.

Drug Metab Dispos. 2013 Apr;41(4):709-13. doi: 10.1124/dmd.112.050625. Epub 2013 Jan 8.

5.

P-glycoprotein is a major determinant of norbuprenorphine brain exposure and antinociception.

Brown SM, Campbell SD, Crafford A, Regina KJ, Holtzman MJ, Kharasch ED.

J Pharmacol Exp Ther. 2012 Oct;343(1):53-61. doi: 10.1124/jpet.112.193433. Epub 2012 Jun 27.

6.

Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamics.

Kharasch ED, Whittington D, Ensign D, Hoffer C, Bedynek PS, Campbell S, Stubbert K, Crafford A, London A, Kim T.

Clin Pharmacol Ther. 2012 Apr;91(4):673-84. doi: 10.1038/clpt.2011.276. Epub 2012 Mar 7.

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