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Items: 1 to 50 of 183

1.

The Adductomics of Isolevuglandins: Oxidation of IsoLG Pyrrole Intermediates Generates Pyrrole⁻Pyrrole Crosslinks and Lactams.

Bi W, Jang GF, Zhang L, Crabb JW, Laird J, Linetsky M, Salomon RG.

High Throughput. 2019 May 10;8(2). pii: E12. doi: 10.3390/ht8020012.

2.

Lipocalin 2 Plays an Important Role in Regulating Inflammation in Retinal Degeneration.

Parmar T, Parmar VM, Perusek L, Georges A, Takahashi M, Crabb JW, Maeda A.

J Immunol. 2018 May 1;200(9):3128-3141. doi: 10.4049/jimmunol.1701573. Epub 2018 Mar 30.

3.

Molecular Structures of Isolevuglandin-Protein Cross-Links.

Bi W, Jang GF, Zhang L, Crabb JW, Laird J, Linetsky M, Salomon RG.

Chem Res Toxicol. 2016 Oct 17;29(10):1628-1640. Epub 2016 Sep 21.

4.

Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma.

Triozzi PL, Achberger S, Aldrich W, Crabb JW, Saunthararajah Y, Singh AD.

Clin Epigenetics. 2016 Jul 22;8:80. doi: 10.1186/s13148-016-0243-0. eCollection 2016.

5.

Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.

Tayou J, Wang Q, Jang GF, Pronin AN, Orlandi C, Martemyanov KA, Crabb JW, Slepak VZ.

J Biol Chem. 2016 Apr 22;291(17):9133-47. doi: 10.1074/jbc.M115.694075. Epub 2016 Feb 19.

6.

Spontaneous cellular and humoral tumor antigen responses in patients with uveal melanoma.

Triozzi PL, Aldrich W, Crabb JW, Singh AD.

Melanoma Res. 2015 Dec;25(6):510-8. doi: 10.1097/CMR.0000000000000207.

PMID:
26397048
7.

iTRAQ Quantitative Proteomic Comparison of Metastatic and Non-Metastatic Uveal Melanoma Tumors.

Crabb JW, Hu B, Crabb JS, Triozzi P, Saunthararajah Y, Tubbs R, Singh AD.

PLoS One. 2015 Aug 25;10(8):e0135543. doi: 10.1371/journal.pone.0135543. eCollection 2015.

8.

Receptor-Mediated Mechanism Controlling Tissue Levels of Bioactive Lipid Oxidation Products.

Kim YW, Yakubenko VP, West XZ, Gugiu GB, Renganathan K, Biswas S, Gao D, Crabb JW, Salomon RG, Podrez EA, Byzova TV.

Circ Res. 2015 Jul 31;117(4):321-32. doi: 10.1161/CIRCRESAHA.117.305925. Epub 2015 May 12.

9.

Detection and biological activities of carboxyethylpyrrole ethanolamine phospholipids (CEP-EPs).

Wang H, Guo J, West XZ, Bid HK, Lu L, Hong L, Jang GF, Zhang L, Crabb JW; Clinical Genomic and Proteomic AMD Study Group, Linetsky M, Salomon RG.

Chem Res Toxicol. 2014 Dec 15;27(12):2015-22. doi: 10.1021/tx500216a. Epub 2014 Nov 19.

10.

The proteomics of drusen.

Crabb JW.

Cold Spring Harb Perspect Med. 2014 May 5;4(7):a017194. doi: 10.1101/cshperspect.a017194. Review.

11.

Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy.

Gu X, Hu Z, Ebrahem Q, Crabb JS, Mahfouz RZ, Radivoyevitch T, Crabb JW, Saunthararajah Y.

J Biol Chem. 2014 May 23;289(21):14881-95. doi: 10.1074/jbc.M114.562447. Epub 2014 Apr 2.

12.

Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease.

Achberger S, Aldrich W, Tubbs R, Crabb JW, Singh AD, Triozzi PL.

Mol Immunol. 2014 Apr;58(2):182-6. doi: 10.1016/j.molimm.2013.11.018. Epub 2013 Dec 25.

13.

CEP biomarkers as potential tools for monitoring therapeutics.

Renganathan K, Gu J, Rayborn ME, Crabb JS, Salomon RG, Collier RJ, Kapin MA, Romano C, Hollyfield JG, Crabb JW.

PLoS One. 2013 Oct 1;8(10):e76325. doi: 10.1371/journal.pone.0076325. eCollection 2013.

14.

Protein partners of dynamin-1 in the retina.

Grossman GH, Ebke LA, Beight CD, Jang GF, Crabb JW, Hagstrom SA.

Vis Neurosci. 2013 Jul;30(4):129-39. doi: 10.1017/S0952523813000138. Epub 2013 Jun 10.

15.

Proteomic similarities in steroid responsiveness in normal and glaucomatous trabecular meshwork cells.

Bollinger KE, Crabb JS, Yuan X, Putliwala T, Clark AF, Crabb JW.

Mol Vis. 2012;18:2001-11. Epub 2012 Jul 20.

16.

Age-related changes in the retinal pigment epithelium (RPE).

Gu X, Neric NJ, Crabb JS, Crabb JW, Bhattacharya SK, Rayborn ME, Hollyfield JG, Bonilha VL.

PLoS One. 2012;7(6):e38673. doi: 10.1371/journal.pone.0038673. Epub 2012 Jun 11.

17.

Quantitative proteomics: TGFβ₂ signaling in trabecular meshwork cells.

Bollinger KE, Crabb JS, Yuan X, Putliwala T, Clark AF, Crabb JW.

Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8287-94. doi: 10.1167/iovs.11-8218.

18.

Circulating tumor cells in uveal melanoma.

Torres V, Triozzi P, Eng C, Tubbs R, Schoenfiled L, Crabb JW, Saunthararajah Y, Singh AD.

Future Oncol. 2011 Jan;7(1):101-9. doi: 10.2217/fon.10.143. Review.

PMID:
21174541
19.

Preliminary quantitative proteomic characterization of glaucomatous rat retinal ganglion cells.

Crabb JW, Yuan X, Dvoriantchikova G, Ivanov D, Crabb JS, Shestopalov VI.

Exp Eye Res. 2010 Jul;91(1):107-10. doi: 10.1016/j.exer.2010.04.004. Epub 2010 Apr 20.

20.

Proteomic and genomic biomarkers for age-related macular degeneration.

Gu J, Pauer GJ, Yue X, Narendra U, Sturgill GM, Bena J, Gu X, Peachey NS, Salomon RG, Hagstrom SA, Crabb JW; Clinical Genomic and Proteomic AMD Study Group.

Adv Exp Med Biol. 2010;664:411-7. doi: 10.1007/978-1-4419-1399-9_47.

PMID:
20238042
21.

Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes.

Yuan X, Gu X, Crabb JS, Yue X, Shadrach K, Hollyfield JG, Crabb JW.

Mol Cell Proteomics. 2010 Jun;9(6):1031-46. doi: 10.1074/mcp.M900523-MCP200. Epub 2010 Feb 22.

22.

Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts.

Li W, Laird JM, Lu L, Roychowdhury S, Nagy LE, Zhou R, Crabb JW, Salomon RG.

Free Radic Biol Med. 2009 Dec 1;47(11):1539-52. doi: 10.1016/j.freeradbiomed.2009.09.003. Epub 2009 Sep 12.

23.

Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.

Ni J, Yuan X, Gu J, Yue X, Gu X, Nagaraj RH, Crabb JW; Clinical Genomic and Proteomic AMD Study Group.

Mol Cell Proteomics. 2009 Aug;8(8):1921-33. doi: 10.1074/mcp.M900127-MCP200. Epub 2009 May 11.

24.

Glucose-modulated tyrosine nitration in beta cells: targets and consequences.

Koeck T, Corbett JA, Crabb JW, Stuehr DJ, Aulak KS.

Arch Biochem Biophys. 2009 Apr 15;484(2):221-31.

25.

Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.

Gu J, Pauer GJ, Yue X, Narendra U, Sturgill GM, Bena J, Gu X, Peachey NS, Salomon RG, Hagstrom SA, Crabb JW; Clinical Genomic and Proteomic AMD Study Group.

Mol Cell Proteomics. 2009 Jun;8(6):1338-49. doi: 10.1074/mcp.M800453-MCP200. Epub 2009 Feb 6.

26.

Glucose-mediated tyrosine nitration in adipocytes: targets and consequences.

Koeck T, Willard B, Crabb JW, Kinter M, Stuehr DJ, Aulak KS.

Free Radic Biol Med. 2009 Apr 1;46(7):884-92. doi: 10.1016/j.freeradbiomed.2008.12.010. Epub 2008 Dec 24.

27.

Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localization.

Rosenzweig DH, Nair KS, Levay K, Peshenko IV, Crabb JW, Dizhoor AM, Slepak VZ.

Biochem J. 2009 Feb 1;417(3):803-12. doi: 10.1042/BJ20081513.

28.

Low-density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE): detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE.

Annangudi SP, Deng Y, Gu X, Zhang W, Crabb JW, Salomon RG.

Chem Res Toxicol. 2008 Jul;21(7):1384-95. doi: 10.1021/tx8000303. Epub 2008 Jun 21.

29.

Duplication and divergence of zebrafish CRALBP genes uncovers novel role for RPE- and Muller-CRALBP in cone vision.

Collery R, McLoughlin S, Vendrell V, Finnegan J, Crabb JW, Saari JC, Kennedy BN.

Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3812-20. doi: 10.1167/iovs.08-1957. Epub 2008 May 23.

PMID:
18502992
30.

Retinal pigment epithelium lipofuscin proteomics.

Ng KP, Gugiu B, Renganathan K, Davies MW, Gu X, Crabb JS, Kim SR, Rózanowska MB, Bonilha VL, Rayborn ME, Salomon RG, Sparrow JR, Boulton ME, Hollyfield JG, Crabb JW.

Mol Cell Proteomics. 2008 Jul;7(7):1397-405. doi: 10.1074/mcp.M700525-MCP200. Epub 2008 Apr 24.

31.

Amino acid analysis.

Crabb JW, West KA, Dodson WS, Hulmes JD.

Curr Protoc Protein Sci. 2001 May;Chapter 11:Unit 11.9. doi: 10.1002/0471140864.ps1109s07.

PMID:
18429107
32.

CRALBP is a highly prevalent autoantigen for human autoimmune uveitis.

Deeg CA, Raith AJ, Amann B, Crabb JW, Thurau SR, Hauck SM, Ueffing M, Wildner G, Stangassinger M.

Clin Dev Immunol. 2007;2007:39245. doi: 10.1155/2007/39245.

33.

Carboxyethylpyrrole adducts, age-related macular degeneration and neovascularization.

Renganathan K, Ebrahem Q, Vasanji A, Gu X, Lu L, Sears J, Salomon RG, Anand-Apte B, Crabb JW.

Adv Exp Med Biol. 2008;613:261-7. doi: 10.1007/978-0-387-74904-4_30. Review. No abstract available.

PMID:
18188953
34.

Targets of tyrosine nitration in diabetic rat retina.

Zhan X, Du Y, Crabb JS, Gu X, Kern TS, Crabb JW.

Mol Cell Proteomics. 2008 May;7(5):864-74. doi: 10.1074/mcp.M700417-MCP200. Epub 2007 Dec 28. Erratum in: Mol Cell Proteomics. 2008 Jun;7(6):1188-9. Retraction in: Mol Cell Proteomics. 2011 Aug;10(8):A700417MCP200.

35.

SOD2 knockdown mouse model of early AMD.

Justilien V, Pang JJ, Renganathan K, Zhan X, Crabb JW, Kim SR, Sparrow JR, Hauswirth WW, Lewin AS.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4407-20.

36.

Interaction between the photoreceptor-specific tubby-like protein 1 and the neuronal-specific GTPase dynamin-1.

Xi Q, Pauer GJ, Ball SL, Rayborn M, Hollyfield JG, Peachey NS, Crabb JW, Hagstrom SA.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2837-44.

37.

The retinal pigment epithelium apical microvilli and retinal function.

Bonilha VL, Rayborn ME, Bhattacharya SK, Gu X, Crabb JS, Crabb JW, Hollyfield JG.

Adv Exp Med Biol. 2006;572:519-24. Review. No abstract available.

38.

CRALBP ligand and protein interactions.

Wu Z, Bhattacharya SK, Jin Z, Bonilha VL, Liu T, Nawrot M, Teller DC, Saari JC, Crabb JW.

Adv Exp Med Biol. 2006;572:477-83. No abstract available.

PMID:
17249612
39.

Annexins in Bruch's membrane and drusen.

Rayborn ME, Sakaguchi H, Shadrach KG, Crabb JW, Hollyfield JG.

Adv Exp Med Biol. 2006;572:75-8. No abstract available.

PMID:
17249558
40.

Mutation screen of the cone-specific gene, CLUL1, in 376 patients with age-related macular degeneration.

Sturgill GM, Pauer GJ, Bala E, Simpson E, Yaniglos SS, Crabb JW, Hollyfield JG, Lewis H, Peachey NS, Hagstrom SA.

Ophthalmic Genet. 2006 Dec;27(4):151-5.

41.

Clathrin and adaptin accumulation in drusen, Bruch's membrane and choroid in AMD and non-AMD donor eyes.

Bando H, Shadrach KG, Rayborn ME, Crabb JW, Hollyfield JG.

Exp Eye Res. 2007 Jan;84(1):135-42. Epub 2006 Nov 13.

PMID:
17097084
42.

Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1.

Hoppe G, Talcott KE, Bhattacharya SK, Crabb JW, Sears JE.

Exp Cell Res. 2006 Nov 1;312(18):3526-38. Epub 2006 Aug 2.

PMID:
16962095
43.

Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration.

Ebrahem Q, Renganathan K, Sears J, Vasanji A, Gu X, Lu L, Salomon RG, Crabb JW, Anand-Apte B.

Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13480-4. Epub 2006 Aug 25. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15722.

44.

Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis.

Bhattacharya SK, Crabb JS, Bonilha VL, Gu X, Takahara H, Crabb JW.

Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2508-14.

PMID:
16723463
45.

Genetic, age and light mediated effects on crystallin protein expression in the retina.

Organisciak D, Darrow R, Gu X, Barsalou L, Crabb JW.

Photochem Photobiol. 2006 Jul-Aug;82(4):1088-96.

PMID:
16602829
46.

Scaffold proteins and the regeneration of visual pigments.

Nawrot M, Liu T, Garwin GG, Crabb JW, Saari JC.

Photochem Photobiol. 2006 Nov-Dec;82(6):1482-8.

PMID:
16553463
47.

Characterization of semenogelin proteins in the human retina.

Bonilha VL, Rayborn ME, Shadrach K, Lundwall A, Malm J, Bhattacharya SK, Crabb JW, Hollyfield JG.

Exp Eye Res. 2006 Jul;83(1):120-7. Epub 2006 Mar 20.

PMID:
16545373
48.

Identification of oxidatively truncated ethanolamine phospholipids in retina and their generation from polyunsaturated phosphatidylethanolamines.

Gugiu BG, Mesaros CA, Sun M, Gu X, Crabb JW, Salomon RG.

Chem Res Toxicol. 2006 Feb;19(2):262-71.

PMID:
16485902
49.

Cochlin and glaucoma: a mini-review.

Bhattacharya SK, Peachey NS, Crabb JW.

Vis Neurosci. 2005 Sep-Oct;22(5):605-13. Review.

50.

Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells.

Datta J, Majumder S, Bai S, Ghoshal K, Kutay H, Smith DS, Crabb JW, Jacob ST.

Cancer Res. 2005 Dec 1;65(23):10891-900.

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