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Items: 49


Influence of the lung microbiome on antibiotic susceptibility of cystic fibrosis pathogens.

Vandeplassche E, Tavernier S, Coenye T, Crabbé A.

Eur Respir Rev. 2019 Jul 8;28(152). pii: 190041. doi: 10.1183/16000617.0041-2019. Print 2019 Jun 30.

Free Article

Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms.

Crabbé A, Jensen PØ, Bjarnsholt T, Coenye T.

Trends Microbiol. 2019 Jun 6. pii: S0966-842X(19)30126-X. doi: 10.1016/j.tim.2019.05.003. [Epub ahead of print] Review.


Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics.

Crabbé A, Ostyn L, Staelens S, Rigauts C, Risseeuw M, Dhaenens M, Daled S, Van Acker H, Deforce D, Van Calenbergh S, Coenye T.

PLoS Pathog. 2019 Apr 29;15(4):e1007697. doi: 10.1371/journal.ppat.1007697. eCollection 2019 Apr.


The Antimicrobial Peptide lin-SB056-1 and Its Dendrimeric Derivative Prevent Pseudomonas aeruginosa Biofilm Formation in Physiologically Relevant Models of Chronic Infections.

Grassi L, Batoni G, Ostyn L, Rigole P, Van den Bossche S, Rinaldi AC, Maisetta G, Esin S, Coenye T, Crabbé A.

Front Microbiol. 2019 Feb 8;10:198. doi: 10.3389/fmicb.2019.00198. eCollection 2019.


Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms.

Sass A, Slachmuylders L, Van Acker H, Vandenbussche I, Ostyn L, Bové M, Crabbé A, Chiarelli LR, Buroni S, Van Nieuwerburgh F, Abatih E, Coenye T.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02092-18. doi: 10.1128/AAC.02092-18. Print 2019 Apr.


Coumarin Reduces Virulence and Biofilm Formation in Pseudomonas aeruginosa by Affecting Quorum Sensing, Type III Secretion and C-di-GMP Levels.

Zhang Y, Sass A, Van Acker H, Wille J, Verhasselt B, Van Nieuwerburgh F, Kaever V, Crabbé A, Coenye T.

Front Microbiol. 2018 Aug 21;9:1952. doi: 10.3389/fmicb.2018.01952. eCollection 2018.


Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age.

Barrila J, Crabbé A, Yang J, Franco K, Nydam SD, Forsyth RJ, Davis RR, Gangaraju S, Ott CM, Coyne CB, Bissell MJ, Nickerson CA.

Infect Immun. 2018 Oct 25;86(11). pii: e00282-18. doi: 10.1128/IAI.00282-18. Print 2018 Nov. Review.


Decreased susceptibility of Streptococcus anginosus to vancomycin in a multispecies biofilm is due to increased thickness of the cell wall.

Tavernier S, Sass A, De Bruyne M, Baeke F, De Rycke R, Crabbé A, Vandecandelaere I, Van Nieuwerburgh F, Coenye T.

J Antimicrob Chemother. 2018 Sep 1;73(9):2323-2330. doi: 10.1093/jac/dky216.


Influence of three-dimensional lung epithelial cells and interspecies interactions on antibiotic efficacy against Mycobacterium abscessus and Pseudomonas aeruginosa.

Rodríguez-Sevilla G, Rigauts C, Vandeplassche E, Ostyn L, Mahíllo-Fernández I, Esteban J, Peremarch CP, Coenye T, Crabbé A.

Pathog Dis. 2018 Jun 1;76(4). doi: 10.1093/femspd/fty034.


Intrapulmonary percussive ventilation improves lung function in cystic fibrosis patients chronically colonized with Pseudomonas aeruginosa: a pilot cross-over study.

Dingemans J, Eyns H, Willekens J, Monsieurs P, Van Houdt R, Cornelis P, Malfroot A, Crabbé A.

Eur J Clin Microbiol Infect Dis. 2018 Jun;37(6):1143-1151. doi: 10.1007/s10096-018-3232-8. Epub 2018 Mar 20.


Developing selective media for quantification of multispecies biofilms following antibiotic treatment.

Vandeplassche E, Coenye T, Crabbé A.

PLoS One. 2017 Nov 9;12(11):e0187540. doi: 10.1371/journal.pone.0187540. eCollection 2017.


Spaceflight modulates gene expression in the whole blood of astronauts.

Barrila J, Ott CM, LeBlanc C, Mehta SK, Crabbé A, Stafford P, Pierson DL, Nickerson CA.

NPJ Microgravity. 2016 Dec 8;2:16039. doi: 10.1038/npjmgrav.2016.39. eCollection 2016.


Community Composition Determines Activity of Antibiotics against Multispecies Biofilms.

Tavernier S, Crabbé A, Hacioglu M, Stuer L, Henry S, Rigole P, Dhondt I, Coenye T.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00302-17. doi: 10.1128/AAC.00302-17. Print 2017 Sep.


Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns.

Barrila J, Yang J, Crabbé A, Sarker SF, Liu Y, Ott CM, Nelman-Gonzalez MA, Clemett SJ, Nydam SD, Forsyth RJ, Davis RR, Crucian BE, Quiriarte H, Roland KL, Brenneman K, Sams C, Loscher C, Nickerson CA.

NPJ Microgravity. 2017 Feb 28;3:10. doi: 10.1038/s41526-017-0011-2. eCollection 2017.


Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum.

Crabbé A, Liu Y, Matthijs N, Rigole P, De La Fuente-Nùñez C, Davis R, Ledesma MA, Sarker S, Van Houdt R, Hancock RE, Coenye T, Nickerson CA.

Sci Rep. 2017 Mar 3;7:43321. doi: 10.1038/srep43321.


Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models.

Van den Driessche F, Vanhoutte B, Brackman G, Crabbé A, Rigole P, Vercruysse J, Verstraete G, Cappoen D, Vervaet C, Cos P, Coenye T.

PLoS One. 2017 Mar 1;12(3):e0172723. doi: 10.1371/journal.pone.0172723. eCollection 2017.


Melamine-Formaldehyde Microcapsules: Micro- and Nanostructural Characterization with Electron Microscopy.

Heidari H, Rivero G, Idrissi H, Ramachandran D, Cakir S, Egoavil R, Kurttepeli M, Crabbé AC, Hauffman T, Terryn H, Du Prez F, Schryvers D.

Microsc Microanal. 2016 Dec;22(6):1222-1232. doi: 10.1017/S1431927616012484.


Practical Use of Thromboelastometry in the Management of Perioperative Coagulopathy and Bleeding.

Williams B, McNeil J, Crabbe A, Tanaka KA.

Transfus Med Rev. 2017 Jan;31(1):11-25. doi: 10.1016/j.tmrv.2016.08.005. Epub 2016 Aug 27. Review.


Effect of Shear Stress on Pseudomonas aeruginosa Isolated from the Cystic Fibrosis Lung.

Dingemans J, Monsieurs P, Yu SH, Crabbé A, Förstner KU, Malfroot A, Cornelis P, Van Houdt R.

MBio. 2016 Aug 2;7(4). pii: e00813-16. doi: 10.1128/mBio.00813-16.


TEM and AES investigations of the natural surface nano-oxide layer of an AISI 316L stainless steel microfibre.

Ramachandran D, Egoavil R, Crabbe A, Hauffman T, Abakumov A, Verbeeck J, Vandendael I, Terryn H, Schryvers D.

J Microsc. 2016 Nov;264(2):207-214. doi: 10.1111/jmi.12434. Epub 2016 Jun 17.


Therapeutic plasma exchange in heart transplantation: role of coagulation assessment with thromboelastometry.

Crabbe A, McNeil JS, Deshpande SP, Kon Z, Pham SM, Tanaka KA.

JA Clin Rep. 2016;2(1):31. doi: 10.1186/s40981-016-0058-1. Epub 2016 Oct 19.


Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture.

Crabbé A, Liu Y, Sarker SF, Bonenfant NR, Barrila J, Borg ZD, Lee JJ, Weiss DJ, Nickerson CA.

PLoS One. 2015 May 11;10(5):e0126846. doi: 10.1371/journal.pone.0126846. eCollection 2015.


Mimicking the host and its microenvironment in vitro for studying mucosal infections by Pseudomonas aeruginosa.

Crabbé A, Ledesma MA, Nickerson CA.

Pathog Dis. 2014 Jun;71(1):1-19. doi: 10.1111/2049-632X.12180. Epub 2014 May 23. Review.


The deletion of TonB-dependent receptor genes is part of the genome reduction process that occurs during adaptation of Pseudomonas aeruginosa to the cystic fibrosis lung.

Dingemans J, Ye L, Hildebrand F, Tontodonati F, Craggs M, Bilocq F, De Vos D, Crabbé A, Van Houdt R, Malfroot A, Cornelis P.

Pathog Dis. 2014 Jun;71(1):26-38. doi: 10.1111/2049-632X.12170. Epub 2014 Apr 16.


Spaceflight enhances cell aggregation and random budding in Candida albicans.

Crabbé A, Nielsen-Preiss SM, Woolley CM, Barrila J, Buchanan K, McCracken J, Inglis DO, Searles SC, Nelman-Gonzalez MA, Ott CM, Wilson JW, Pierson DL, Stefanyshyn-Piper HM, Hyman LE, Nickerson CA.

PLoS One. 2013 Dec 4;8(12):e80677. doi: 10.1371/journal.pone.0080677. eCollection 2013.


Insights into the role of oxidative stress in the pathology of Friedreich ataxia using peroxidation resistant polyunsaturated fatty acids.

Cotticelli MG, Crabbe AM, Wilson RB, Shchepinov MS.

Redox Biol. 2013;1:398-404. doi: 10.1016/j.redox.2013.06.004. Epub 2013 Jul 19.


Differential proteomics and physiology of Pseudomonas putida KT2440 under filament-inducing conditions.

Crabbé A, Leroy B, Wattiez R, Aertsen A, Leys N, Cornelis P, Van Houdt R.

BMC Microbiol. 2012 Nov 27;12:282. doi: 10.1186/1471-2180-12-282.


MAPC culture conditions support the derivation of cells with nascent hypoblast features from bone marrow and blastocysts.

Lo Nigro A, Geraerts M, Notelaers T, Roobrouck VD, Muijtjens M, Eggermont K, Subramanian K, Ulloa-Montoya F, Park Y, Owens J, Burns TC, Low W, Sharma S, Sohni A, Crabbe A, Pauwelyn K, Roelandt P, Agirre X, Prosper F, O'Brien TD, Zwijsen A, Hu WS, Binas B, Verfaillie CM.

J Mol Cell Biol. 2012 Dec;4(6):423-6. doi: 10.1093/jmcb/mjs046. Epub 2012 Aug 9. No abstract available.


Glycerol supplementation enhances L. reuteri's protective effect against S. Typhimurium colonization in a 3-D model of colonic epithelium.

De Weirdt R, Crabbé A, Roos S, Vollenweider S, Lacroix C, van Pijkeren JP, Britton RA, Sarker S, Van de Wiele T, Nickerson CA.

PLoS One. 2012;7(5):e37116. doi: 10.1371/journal.pone.0037116. Epub 2012 May 31.


New insights into the bacterial fitness-associated mechanisms revealed by the characterization of large plasmids of an avian pathogenic E. coli.

Mellata M, Maddux JT, Nam T, Thomson N, Hauser H, Stevens MP, Mukhopadhyay S, Sarker S, Crabbé A, Nickerson CA, Santander J, Curtiss R 3rd.

PLoS One. 2012;7(1):e29481. doi: 10.1371/journal.pone.0029481. Epub 2012 Jan 4.


Phenotypic and genome-wide analysis of an antibiotic-resistant small colony variant (SCV) of Pseudomonas aeruginosa.

Wei Q, Tarighi S, Dötsch A, Häussler S, Müsken M, Wright VJ, Cámara M, Williams P, Haenen S, Boerjan B, Bogaerts A, Vierstraete E, Verleyen P, Schoofs L, Willaert R, De Groote VN, Michiels J, Vercammen K, Crabbé A, Cornelis P.

PLoS One. 2011;6(12):e29276. doi: 10.1371/journal.pone.0029276. Epub 2011 Dec 15.


Improving adherence with amlodipine/atorvastatin therapy: IMPACT study.

Oliver S, Jones J, Leonard D, Crabbe A, Delkhah Y, Nesbitt S.

J Clin Hypertens (Greenwich). 2011 Aug;13(8):598-604. doi: 10.1111/j.1751-7176.2011.00478.x. Epub 2011 Jun 29. Erratum in: J Clin Hypertens (Greenwich). 2011 Oct;13(10):784. Nesbitt, Shawna [added].


Transcriptional and proteomic responses of Pseudomonas aeruginosa PAO1 to spaceflight conditions involve Hfq regulation and reveal a role for oxygen.

Crabbé A, Schurr MJ, Monsieurs P, Morici L, Schurr J, Wilson JW, Ott CM, Tsaprailis G, Pierson DL, Stefanyshyn-Piper H, Nickerson CA.

Appl Environ Microbiol. 2011 Feb;77(4):1221-30. doi: 10.1128/AEM.01582-10. Epub 2010 Dec 17.


Alveolar epithelium protects macrophages from quorum sensing-induced cytotoxicity in a three-dimensional co-culture model.

Crabbé A, Sarker SF, Van Houdt R, Ott CM, Leys N, Cornelis P, Nickerson CA.

Cell Microbiol. 2011 Mar;13(3):469-81. doi: 10.1111/j.1462-5822.2010.01548.x. Epub 2010 Nov 25.


Organotypic 3D cell culture models: using the rotating wall vessel to study host-pathogen interactions.

Barrila J, Radtke AL, Crabbé A, Sarker SF, Herbst-Kralovetz MM, Ott CM, Nickerson CA.

Nat Rev Microbiol. 2010 Nov;8(11):791-801. doi: 10.1038/nrmicro2423. Review.


Characterization of the inflammatory response in a photothrombotic stroke model by MRI: implications for stem cell transplantation.

Vandeputte C, Thomas D, Dresselaers T, Crabbe A, Verfaillie C, Baekelandt V, Van Laere K, Himmelreich U.

Mol Imaging Biol. 2011 Aug;13(4):663-71. doi: 10.1007/s11307-010-0395-9.


The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor.

Skardal A, Sarker SF, Crabbé A, Nickerson CA, Prestwich GD.

Biomaterials. 2010 Nov;31(32):8426-35. doi: 10.1016/j.biomaterials.2010.07.047. Epub 2010 Aug 7.


Effects of MRI contrast agents on the stem cell phenotype.

Crabbe A, Vandeputte C, Dresselaers T, Sacido AA, Verdugo JM, Eyckmans J, Luyten FP, Van Laere K, Verfaillie CM, Himmelreich U.

Cell Transplant. 2010;19(8):919-36. doi: 10.3727/096368910X494623. Epub 2010 Mar 26.


Characterization of triclosan-resistant mutants reveals multiple antimicrobial resistance mechanisms in Rhodospirillum rubrum S1H.

Pycke BF, Crabbé A, Verstraete W, Leys N.

Appl Environ Microbiol. 2010 May;76(10):3116-23. doi: 10.1128/AEM.02757-09. Epub 2010 Mar 19.


Response of Pseudomonas aeruginosa PAO1 to low shear modelled microgravity involves AlgU regulation.

Crabbé A, Pycke B, Van Houdt R, Monsieurs P, Nickerson C, Leys N, Cornelis P.

Environ Microbiol. 2010 Jun;12(6):1545-64. doi: 10.1111/j.1462-2920.2010.02184.x. Epub 2010 Mar 5.


Media ion composition controls regulatory and virulence response of Salmonella in spaceflight.

Wilson JW, Ott CM, Quick L, Davis R, Höner zu Bentrup K, Crabbé A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA.

PLoS One. 2008;3(12):e3923. doi: 10.1371/journal.pone.0003923. Epub 2008 Dec 12.


Use of the rotating wall vessel technology to study the effect of shear stress on growth behaviour of Pseudomonas aeruginosa PA01.

Crabbé A, De Boever P, Van Houdt R, Moors H, Mergeay M, Cornelis P.

Environ Microbiol. 2008 Aug;10(8):2098-110. doi: 10.1111/j.1462-2920.2008.01631.x. Epub 2008 Apr 22.


Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity.

Ulloa-Montoya F, Kidder BL, Pauwelyn KA, Chase LG, Luttun A, Crabbe A, Geraerts M, Sharov AA, Piao Y, Ko MS, Hu WS, Verfaillie CM.

Genome Biol. 2007;8(8):R163.


The notch signaling system is present in the postnatal pituitary: marked expression and regulatory activity in the newly discovered side population.

Chen J, Crabbe A, Van Duppen V, Vankelecom H.

Mol Endocrinol. 2006 Dec;20(12):3293-307. Epub 2006 Sep 7.


Testing of a dual-mode microwave care regimen for hydrogel lenses.

Crabbe A, Thompson P.

Optom Vis Sci. 2004 Jun;81(6):471-7.


Effects of microwave irradiation on the parameters of hydrogel contact lenses.

Crabbe A, Thompson P.

Optom Vis Sci. 2001 Aug;78(8):610-5.


Clinical trial of a patient-operated microwave care system for hydrogel contact lenses.

Crabbe A, Thompson P.

Optom Vis Sci. 2001 Aug;78(8):605-9.


Charter Medical's purchasing chief stresses role of product evaluation panels. Interview by Dan Dildine.

Crabbe A.

HPN Hosp Purch News. 1982 Jun;6(6):21-3. No abstract available.



Crabbe AE, Broster LR.

Br Med J. 1922 Oct 21;2(3225):717-8. No abstract available.

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