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Items: 1 to 50 of 134

1.

An insight into future antibacterial therapy.

Cozzone AJ.

Emerg Microbes Infect. 2012 Nov;1(11):e38. doi: 10.1038/emi.2012.35. Epub 2012 Nov 7. No abstract available.

2.

The extended conformation of the 2.9-Å crystal structure of the three-PASTA domain of a Ser/Thr kinase from the human pathogen Staphylococcus aureus.

Paracuellos P, Ballandras A, Robert X, Kahn R, Hervé M, Mengin-Lecreulx D, Cozzone AJ, Duclos B, Gouet P.

J Mol Biol. 2010 Dec 17;404(5):847-58. doi: 10.1016/j.jmb.2010.10.012. Epub 2010 Oct 19.

PMID:
20965199
3.

The Staphylococcus aureus autoinducer-2 synthase LuxS is regulated by Ser/Thr phosphorylation.

Cluzel ME, Zanella-Cléon I, Cozzone AJ, Fütterer K, Duclos B, Molle V.

J Bacteriol. 2010 Dec;192(23):6295-301. doi: 10.1128/JB.00853-10. Epub 2010 Sep 24.

4.

Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export.

Bechet E, Gruszczyk J, Terreux R, Gueguen-Chaignon V, Vigouroux A, Obadia B, Cozzone AJ, Nessler S, Grangeasse C.

Mol Microbiol. 2010 Sep;77(5):1315-25. doi: 10.1111/j.1365-2958.2010.07291.x.

5.

Phosphorylation of the virulence regulator SarA modulates its ability to bind DNA in Staphylococcus aureus.

Didier JP, Cozzone AJ, Duclos B.

FEMS Microbiol Lett. 2010 May;306(1):30-6. doi: 10.1111/j.1574-6968.2010.01930.x. Epub 2010 Feb 19.

6.

Crystallization and initial X-ray diffraction study of the three PASTA domains of the Ser/Thr kinase Stk1 from the human pathogen Staphylococcus aureus.

Paracuellos P, Ballandras A, Robert X, Cozzone AJ, Duclos B, Gouet P.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 1;65(Pt 11):1187-9. doi: 10.1107/S174430910904250X. Epub 2009 Oct 30.

7.

Bacterial tyrosine kinases: novel targets for antibacterial therapy?

Cozzone AJ.

Trends Microbiol. 2009 Dec;17(12):536-43. doi: 10.1016/j.tim.2009.09.005. Epub 2009 Oct 21.

PMID:
19853456
8.

Tyrosine-kinases in bacteria: from a matter of controversy to the status of key regulatory enzymes.

Bechet E, Guiral S, Torres S, Mijakovic I, Cozzone AJ, Grangeasse C.

Amino Acids. 2009 Sep;37(3):499-507. doi: 10.1007/s00726-009-0237-8. Epub 2009 Feb 3. Review.

PMID:
19189200
9.

Identification of the idiosyncratic bacterial protein tyrosine kinase (BY-kinase) family signature.

Jadeau F, Bechet E, Cozzone AJ, Deléage G, Grangeasse C, Combet C.

Bioinformatics. 2008 Nov 1;24(21):2427-30. doi: 10.1093/bioinformatics/btn462. Epub 2008 Sep 3.

PMID:
18772155
10.

Tyrosine phosphorylation of the UDP-glucose dehydrogenase of Escherichia coli is at the crossroads of colanic acid synthesis and polymyxin resistance.

Lacour S, Bechet E, Cozzone AJ, Mijakovic I, Grangeasse C.

PLoS One. 2008 Aug 25;3(8):e3053. doi: 10.1371/journal.pone.0003053.

11.

Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus.

Olivares-Illana V, Meyer P, Bechet E, Gueguen-Chaignon V, Soulat D, Lazereg-Riquier S, Mijakovic I, Deutscher J, Cozzone AJ, Laprévote O, Morera S, Grangeasse C, Nessler S.

PLoS Biol. 2008 Jun 10;6(6):e143. doi: 10.1371/journal.pbio.0060143.

12.

From the characterization of the four serine/threonine protein kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the role of PknA and PknB in cell division.

Fiuza M, Canova MJ, Zanella-Cléon I, Becchi M, Cozzone AJ, Mateos LM, Kremer L, Gil JA, Molle V.

J Biol Chem. 2008 Jun 27;283(26):18099-112. doi: 10.1074/jbc.M802615200. Epub 2008 Apr 28.

13.

A modified His-tag vector for the production of recombinant protein kinases.

Lomas-Lopez R, Cozzone AJ, Duclos B.

Anal Biochem. 2008 Jun 15;377(2):272-3. doi: 10.1016/j.ab.2008.03.002. Epub 2008 Mar 7.

PMID:
18371293
14.

The Mycobacterium tuberculosis serine/threonine kinase PknL phosphorylates Rv2175c: mass spectrometric profiling of the activation loop phosphorylation sites and their role in the recruitment of Rv2175c.

Canova MJ, Veyron-Churlet R, Zanella-Cleon I, Cohen-Gonsaud M, Cozzone AJ, Becchi M, Kremer L, Molle V.

Proteomics. 2008 Feb;8(3):521-33. doi: 10.1002/pmic.200700442.

PMID:
18175374
15.

Induction of human immunodeficiency virus (HIV-1) envelope specific cell-mediated immunity by a non-homologous synthetic peptide.

Achour A, Biquard JM, Krsmanovic V, M'bika JP, Ficheux D, Sikorska M, Cozzone AJ.

PLoS One. 2007 Nov 28;2(11):e1214.

16.

EmbR2, a structural homologue of EmbR, inhibits the Mycobacterium tuberculosis kinase/substrate pair PknH/EmbR.

Molle V, Reynolds RC, Alderwick LJ, Besra GS, Cozzone AJ, Fütterer K, Kremer L.

Biochem J. 2008 Mar 1;410(2):309-17.

PMID:
17999640
17.

UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity.

Soulat D, Grangeasse C, Vaganay E, Cozzone AJ, Duclos B.

J Mol Microbiol Biotechnol. 2007;13(1-3):45-54.

PMID:
17693712
18.

Tyrosine-kinase Wzc from Escherichia coli possesses an ATPase activity regulated by autophosphorylation.

Soulat D, Jault JM, Geourjon C, Gouet P, Cozzone AJ, Grangeasse C.

FEMS Microbiol Lett. 2007 Sep;274(2):252-9. Epub 2007 Jul 12.

19.

Several enzymes of the central metabolism are phosphorylated in Staphylococcus aureus.

Lomas-Lopez R, Paracuellos P, Riberty M, Cozzone AJ, Duclos B.

FEMS Microbiol Lett. 2007 Jul;272(1):35-42. Epub 2007 May 10.

20.

Influence of tyrosine-kinase Wzc activity on colanic acid production in Escherichia coli K12 cells.

Obadia B, Lacour S, Doublet P, Baubichon-Cortay H, Cozzone AJ, Grangeasse C.

J Mol Biol. 2007 Mar 16;367(1):42-53. Epub 2006 Dec 23.

PMID:
17254603
21.

Tyrosine phosphorylation: an emerging regulatory device of bacterial physiology.

Grangeasse C, Cozzone AJ, Deutscher J, Mijakovic I.

Trends Biochem Sci. 2007 Feb;32(2):86-94. Epub 2007 Jan 8. Review.

PMID:
17208443
22.

The condensing activities of the Mycobacterium tuberculosis type II fatty acid synthase are differentially regulated by phosphorylation.

Molle V, Brown AK, Besra GS, Cozzone AJ, Kremer L.

J Biol Chem. 2006 Oct 6;281(40):30094-103. Epub 2006 Jul 27.

23.

A novel role for protein-tyrosine kinase Etk from Escherichia coli K-12 related to polymyxin resistance.

Lacour S, Doublet P, Obadia B, Cozzone AJ, Grangeasse C.

Res Microbiol. 2006 Sep;157(7):637-41. Epub 2006 Feb 17.

PMID:
16814990
24.

Characterization of the phosphorylation sites of Mycobacterium tuberculosis serine/threonine protein kinases, PknA, PknD, PknE, and PknH by mass spectrometry.

Molle V, Zanella-Cleon I, Robin JP, Mallejac S, Cozzone AJ, Becchi M.

Proteomics. 2006 Jul;6(13):3754-66.

PMID:
16739134
25.

Staphylococcus aureus operates protein-tyrosine phosphorylation through a specific mechanism.

Soulat D, Jault JM, Duclos B, Geourjon C, Cozzone AJ, Grangeasse C.

J Biol Chem. 2006 May 19;281(20):14048-56. Epub 2006 Mar 24.

26.

Control of carbon flux through enzymes of central and intermediary metabolism during growth of Escherichia coli on acetate.

El-Mansi M, Cozzone AJ, Shiloach J, Eikmanns BJ.

Curr Opin Microbiol. 2006 Apr;9(2):173-9. Epub 2006 Mar 10. Review.

PMID:
16530464
27.

Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis.

Alderwick LJ, Molle V, Kremer L, Cozzone AJ, Dafforn TR, Besra GS, Fütterer K.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2558-63. Epub 2006 Feb 13.

28.

Role of protein phosphorylation on serine/threonine and tyrosine in the virulence of bacterial pathogens.

Cozzone AJ.

J Mol Microbiol Biotechnol. 2005;9(3-4):198-213. Review.

PMID:
16415593
29.

Control of isocitrate dehydrogenase catalytic activity by protein phosphorylation in Escherichia coli.

Cozzone AJ, El-Mansi M.

J Mol Microbiol Biotechnol. 2005;9(3-4):132-46. Review.

PMID:
16415587
30.

Channel formation by CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii.

Siroy A, Molle V, Lemaître-Guillier C, Vallenet D, Pestel-Caron M, Cozzone AJ, Jouenne T, Dé E.

Antimicrob Agents Chemother. 2005 Dec;49(12):4876-83.

31.

Tyrosine phosphatase MptpA of Mycobacterium tuberculosis inhibits phagocytosis and increases actin polymerization in macrophages.

Castandet J, Prost JF, Peyron P, Astarie-Dequeker C, Anes E, Cozzone AJ, Griffiths G, Maridonneau-Parini I.

Res Microbiol. 2005 Dec;156(10):1005-13. Epub 2005 Jul 19.

PMID:
16085396
32.

Autophosphorylation of the 16 kDa and 70 kDa antigens (Hsp 16.3 and Hsp 70) of Mycobacterium tuberculosis.

Preneta R, Papavinasasundaram KG, Cozzone AJ, Duclos B.

Microbiology. 2004 Jul;150(Pt 7):2135-41.

PMID:
15256556
33.

Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis.

Molle V, Soulat D, Jault JM, Grangeasse C, Cozzone AJ, Prost JF.

FEMS Microbiol Lett. 2004 May 15;234(2):215-23.

34.

Protein phosphorylation on tyrosine in bacteria.

Cozzone AJ, Grangeasse C, Doublet P, Duclos B.

Arch Microbiol. 2004 Mar;181(3):171-81. Epub 2004 Jan 24. Review.

PMID:
14745484
35.

An FHA phosphoprotein recognition domain mediates protein EmbR phosphorylation by PknH, a Ser/Thr protein kinase from Mycobacterium tuberculosis.

Molle V, Kremer L, Girard-Blanc C, Besra GS, Cozzone AJ, Prost JF.

Biochemistry. 2003 Dec 30;42(51):15300-9.

PMID:
14690440
36.

Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis.

Molle V, Girard-Blanc C, Kremer L, Doublet P, Cozzone AJ, Prost JF.

Biochem Biophys Res Commun. 2003 Sep 5;308(4):820-5.

PMID:
12927792
37.

Autophosphorylation of the Escherichia coli protein kinase Wzc regulates tyrosine phosphorylation of Ugd, a UDP-glucose dehydrogenase.

Grangeasse C, Obadia B, Mijakovic I, Deutscher J, Cozzone AJ, Doublet P.

J Biol Chem. 2003 Oct 10;278(41):39323-9. Epub 2003 Jul 7.

38.

Genetically modified organisms: novel technologies and applications.

Cozzone AJ.

Biochimie. 2002 Nov;84(11):1045. No abstract available.

PMID:
12595132
39.

Staphylococcus aureus contains two low-molecular-mass phosphotyrosine protein phosphatases.

Soulat D, Vaganay E, Duclos B, Genestier AL, Etienne J, Cozzone AJ.

J Bacteriol. 2002 Sep;184(18):5194-9.

40.

Structural organization of the protein-tyrosine autokinase Wzc within Escherichia coli cells.

Doublet P, Grangeasse C, Obadia B, Vaganay E, Cozzone AJ.

J Biol Chem. 2002 Oct 4;277(40):37339-48. Epub 2002 Jul 22.

41.

Tyrosine phosphorylation of protein kinase Wzc from Escherichia coli K12 occurs through a two-step process.

Grangeasse C, Doublet P, Cozzone AJ.

J Biol Chem. 2002 Mar 1;277(9):7127-35. Epub 2001 Dec 20.

42.

Isolation and characterization of a protein-tyrosine kinase and a phosphotyrosine-protein phosphatase from Klebsiella pneumoniae.

Preneta R, Jarraud S, Vincent C, Doublet P, Duclos B, Etienne J, Cozzone AJ.

Comp Biochem Physiol B Biochem Mol Biol. 2002 Jan;131(1):103-12.

PMID:
11742763
43.

The "catalytic" triad of isocitrate dehydrogenase kinase/phosphatase from E. coli and its relationship with that found in eukaryotic protein kinases.

Oudot C, Cortay JC, Blanchet C, Laporte DC, Di Pietro A, Cozzone AJ, Jault JM.

Biochemistry. 2001 Mar 13;40(10):3047-55.

PMID:
11258918
44.

Relationship between exopolysaccharide production and protein-tyrosine phosphorylation in gram-negative bacteria.

Vincent C, Duclos B, Grangeasse C, Vaganay E, Riberty M, Cozzone AJ, Doublet P.

J Mol Biol. 2000 Dec 1;304(3):311-21.

PMID:
11090276
45.

Biochemical properties of the protein tyrosine kinase of the bacterium Acinetobacter johnsonii.

Grangeasse C, Vincent C, Doublet P, Cozzone AJ, Duclos B.

IUBMB Life. 1999 Sep;48(3):339-43.

46.

Isolation, cloning, and expression of a new murine zinc finger encoding gene.

Prost JF, Nègre D, Cornet-Javaux F, Cortay JC, Cozzone AJ, Herbage D, Mallein-Gerin F.

Biochim Biophys Acta. 1999 Oct 28;1447(2-3):278-83.

PMID:
10542327
48.

Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, and a phosphotyrosine-protein phosphatase, Wzb.

Vincent C, Doublet P, Grangeasse C, Vaganay E, Cozzone AJ, Duclos B.

J Bacteriol. 1999 Jun;181(11):3472-7.

50.

On the binding of ATP to the autophosphorylating protein, Ptk, of the bacterium Acinetobacter johnsonii.

Doublet P, Vincent C, Grangeasse C, Cozzone AJ, Duclos B.

FEBS Lett. 1999 Feb 19;445(1):137-43.

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