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Treatment planning comparison of volumetric modulated arc therapy employing a dual-layer stacked multi-leaf collimator and helical tomotherapy for cervix uteri.

Panda S, Swamidas J, Chopra S, Mangaj A, Fogliata A, Kupelian P, Agarwal JP, Cozzi L.

Radiat Oncol. 2020 Jan 30;15(1):22. doi: 10.1186/s13014-020-1473-z.


PET/CT radiomics in breast cancer: Mind the step.

Sollini M, Cozzi L, Ninatti G, Antunovic L, Cavinato L, Chiti A, Kirienko M.

Methods. 2020 Jan 21. pii: S1046-2023(19)30263-4. doi: 10.1016/j.ymeth.2020.01.007. [Epub ahead of print] Review.


Intensity modulated proton therapy compared to volumetric modulated arc therapy in the irradiation of young female patients with hodgkin's lymphoma. Assessment of risk of toxicity and secondary cancer induction.

Scorsetti M, Cozzi L, Navarria P, Fogliata A, Rossi A, Franceschini D, De Rose F, Franzese C, Carlo-Stella C, Santoro A.

Radiat Oncol. 2020 Jan 13;15(1):12. doi: 10.1186/s13014-020-1462-2.


A radiomic approach to predicting nodal relapse and disease-specific survival in patients treated with stereotactic body radiation therapy for early-stage non-small cell lung cancer.

Franceschini D, Cozzi L, De Rose F, Navarria P, Fogliata A, Franzese C, Pezzulla D, Tomatis S, Reggiori G, Scorsetti M.

Strahlenther Onkol. 2019 Nov 13. doi: 10.1007/s00066-019-01542-6. [Epub ahead of print]


RapidPlan knowledge based planning: iterative learning process and model ability to steer planning strategies.

Fogliata A, Cozzi L, Reggiori G, Stravato A, Lobefalo F, Franzese C, Franceschini D, Tomatis S, Scorsetti M.

Radiat Oncol. 2019 Oct 30;14(1):187. doi: 10.1186/s13014-019-1403-0.


The Potential Role of Intensity-modulated Proton Therapy in the Regional Nodal Irradiation of Breast Cancer: A Treatment Planning Study.

De Rose F, Cozzi L, Meattini I, Fogliata A, Franceschini D, Franzese C, Tomatis S, Becherini C, Livi L, Scorsetti M.

Clin Oncol (R Coll Radiol). 2020 Jan;32(1):26-34. doi: 10.1016/j.clon.2019.07.016. Epub 2019 Jul 31.


Predicting survival and local control after radiochemotherapy in locally advanced head and neck cancer by means of computed tomography based radiomics.

Cozzi L, Franzese C, Fogliata A, Franceschini D, Navarria P, Tomatis S, Scorsetti M.

Strahlenther Onkol. 2019 Sep;195(9):805-818. doi: 10.1007/s00066-019-01483-0. Epub 2019 Jun 20.


The effect of gender on methotrexate prescription attitudes in Italian rheumatoid arthritis patients: the MARI study.

Giusti A, Epis OM, Migliore A, Ricioppo A, Sainaghi PP, Di Matteo L, Massarotti MS, Govoni M, Mazzone A, Traballi G, Ciarla S, Cozzi L, Roncaglione A, Muratore M, Laurenti R, Bianchi G.

Clin Exp Rheumatol. 2019 Nov-Dec;37(6):1003-1009. Epub 2019 Jun 6.


Impact of hypofractionated schemes in radiotherapy for locally advanced head and neck cancer patients.

Franzese C, Fogliata A, Franceschini D, Navarria P, Cozzi L, Tomatis S, De Virgilio A, Spriano G, Scorsetti M.

Laryngoscope. 2020 Apr;130(4):E163-E170. doi: 10.1002/lary.28048. Epub 2019 May 7.


PET/CT radiomics in breast cancer: promising tool for prediction of pathological response to neoadjuvant chemotherapy.

Antunovic L, De Sanctis R, Cozzi L, Kirienko M, Sagona A, Torrisi R, Tinterri C, Santoro A, Chiti A, Zelic R, Sollini M.

Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1468-1477. doi: 10.1007/s00259-019-04313-8. Epub 2019 Mar 26.


Computed tomography based radiomic signature as predictive of survival and local control after stereotactic body radiation therapy in pancreatic carcinoma.

Cozzi L, Comito T, Fogliata A, Franzese C, Franceschini D, Bonifacio C, Tozzi A, Di Brina L, Clerici E, Tomatis S, Reggiori G, Lobefalo F, Stravato A, Mancosu P, Zerbi A, Sollini M, Kirienko M, Chiti A, Scorsetti M.

PLoS One. 2019 Jan 18;14(1):e0210758. doi: 10.1371/journal.pone.0210758. eCollection 2019.


Phase II trial on SBRT for unresectable liver metastases: long-term outcome and prognostic factors of survival after 5 years of follow-up.

Scorsetti M, Comito T, Clerici E, Franzese C, Tozzi A, Iftode C, Di Brina L, Navarria P, Mancosu P, Reggiori G, Fogliata A, Tomatis S, Torzilli G, Cozzi L.

Radiat Oncol. 2018 Nov 26;13(1):234. doi: 10.1186/s13014-018-1185-9.


Computing of Low Shear Stress-Driven Endothelial Gene Network Involved in Early Stages of Atherosclerotic Process.

Vozzi F, Campolo J, Cozzi L, Politano G, Di Carlo S, Rial M, Domenici C, Parodi O.

Biomed Res Int. 2018 Sep 25;2018:5359830. doi: 10.1155/2018/5359830. eCollection 2018.


Critical Appraisal of the Treatment Planning Performance of Volumetric Modulated Arc Therapy by Means of a Dual Layer Stacked Multileaf Collimator for Head and Neck, Breast, and Prostate.

Cozzi L, Fogliata A, Thompson S, Franzese C, Franceschini D, de Rose F, Tomatis S, Scorsetti M.

Technol Cancer Res Treat. 2018 Jan 1;17:1533033818803882. doi: 10.1177/1533033818803882.


Phase II study of hypofractionated radiation therapy in elderly patients with newly diagnosed glioblastoma with poor prognosis.

Navarria P, Pessina F, Cozzi L, Tomatis S, Reggiori G, Simonelli M, Santoro A, Clerici E, Franzese C, Carta G, Conti Nibali M, Bello L, Scorsetti M.

Tumori. 2019 Feb;105(1):47-54. doi: 10.1177/0300891618792483. Epub 2018 Aug 22.


Critical appraisal of the potential role of intensity modulated proton therapy in the hypofractionated treatment of advanced hepatocellular carcinoma.

Cozzi L, Comito T, Fogliata A, Franzese C, Tomatis S, Scorsetti M.

PLoS One. 2018 Aug 13;13(8):e0201992. doi: 10.1371/journal.pone.0201992. eCollection 2018.


Collimator scatter factor: Monte Carlo and in-air measurements approaches.

Fogliata A, Stravato A, Reggiori G, Tomatis S, Würfel J, Scorsetti M, Cozzi L.

Radiat Oncol. 2018 Jul 11;13(1):126. doi: 10.1186/s13014-018-1070-6.


Is surgical resection useful in elderly newly diagnosed glioblastoma patients? Outcome evaluation and prognostic factors assessment.

Pessina F, Navarria P, Cozzi L, Rudà R, Nibali MC, Simonelli M, Costa F, Santoro A, Clerici E, Carta G, Scorsetti M, Bello L.

Acta Neurochir (Wien). 2018 Sep;160(9):1779-1787. doi: 10.1007/s00701-018-3599-4. Epub 2018 Jul 3.


Evaluation of target dose inhomogeneity in breast cancer treatment due to tissue elemental differences.

Fogliata A, De Rose F, Stravato A, Reggiori G, Tomatis S, Scorsetti M, Cozzi L.

Radiat Oncol. 2018 May 15;13(1):92. doi: 10.1186/s13014-018-1022-1.


Ability of FDG PET and CT radiomics features to differentiate between primary and metastatic lung lesions.

Kirienko M, Cozzi L, Rossi A, Voulaz E, Antunovic L, Fogliata A, Chiti A, Sollini M.

Eur J Nucl Med Mol Imaging. 2018 Sep;45(10):1649-1660. doi: 10.1007/s00259-018-3987-2. Epub 2018 Apr 6.


Dosimetric evaluation of modern radiation therapy techniques for left breast in deep-inspiration breath-hold.

Koivumäki T, Fogliata A, Zeverino M, Boman E, Sierpowska J, Moeckli R, Vallet V, Cozzi L, Heikkilä J, Väänänen A, Vuolukka K, Sillanmäki S, Seppälä J.

Phys Med. 2018 Jan;45:82-87. doi: 10.1016/j.ejmp.2017.12.009. Epub 2017 Dec 19.


Texture analysis and machine learning to characterize suspected thyroid nodules and differentiated thyroid cancer: Where do we stand?

Sollini M, Cozzi L, Chiti A, Kirienko M.

Eur J Radiol. 2018 Feb;99:1-8. doi: 10.1016/j.ejrad.2017.12.004. Epub 2017 Dec 7. Review.


Hypofractionated volumetric modulated arc therapy in ductal carcinoma in situ: toxicity and cosmetic outcome from a prospective series.

De Rose F, Fogliata A, Franceschini D, Iftode C, Torrisi R, Masci G, Sagona A, Tinterri C, Testori A, Gatzemeier W, Fernandes B, Rahal D, Cozzi L, Santoro A, Scorsetti M.

Br J Radiol. 2018 May;91(1085):20170634. doi: 10.1259/bjr.20170634. Epub 2018 Mar 20.


Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis.

Navarria P, Pessina F, Franzese C, Tomatis S, Perrino M, Cozzi L, Simonelli M, Bello L, Clerici E, Riva M, Santoro A, Scorsetti M.

Radiother Oncol. 2018 Apr;127(1):108-113. doi: 10.1016/j.radonc.2017.12.006. Epub 2017 Dec 29.


Critical appraisal of the role of volumetric modulated arc therapy in the radiation therapy management of breast cancer.

Cozzi L, Lohr F, Fogliata A, Franceschini D, De Rose F, Filippi AR, Guidi G, Vanoni V, Scorsetti M.

Radiat Oncol. 2017 Dec 19;12(1):200. doi: 10.1186/s13014-017-0935-4. Review.


Intensity Modulated Radiation Therapy and Second Cancer Risk in Adults.

Filippi AR, Vanoni V, Meduri B, Cozzi L, Scorsetti M, Ricardi U, Lohr F.

Int J Radiat Oncol Biol Phys. 2018 Jan 1;100(1):17-20. doi: 10.1016/j.ijrobp.2017.09.039. No abstract available.


Critical Appraisal of the Risk of Secondary Cancer Induction From Breast Radiation Therapy With Volumetric Modulated Arc Therapy Relative to 3D Conformal Therapy.

Fogliata A, De Rose F, Franceschini D, Stravato A, Seppälä J, Scorsetti M, Cozzi L.

Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):785-793. doi: 10.1016/j.ijrobp.2017.10.040. Epub 2017 Oct 31.


Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury.

Magnaghi P, Salom B, Cozzi L, Amboldi N, Ballinari D, Tamborini E, Gasparri F, Montagnoli A, Raddrizzani L, Somaschini A, Bosotti R, Orrenius C, Bozzi F, Pilotti S, Galvani A, Sommer J, Stacchiotti S, Isacchi A.

Mol Cancer Ther. 2018 Mar;17(3):603-613. doi: 10.1158/1535-7163.MCT-17-0324. Epub 2017 Dec 13.


Radiomics based analysis to predict local control and survival in hepatocellular carcinoma patients treated with volumetric modulated arc therapy.

Cozzi L, Dinapoli N, Fogliata A, Hsu WC, Reggiori G, Lobefalo F, Kirienko M, Sollini M, Franceschini D, Comito T, Franzese C, Scorsetti M, Wang PM.

BMC Cancer. 2017 Dec 6;17(1):829. doi: 10.1186/s12885-017-3847-7.


Outcome Evaluation of HER2 Breast Cancer Patients with Limited Brain Metastasis.

Pessina F, Navarria P, Cozzi L, Franceschini D, Tomatis S, Clerici E, Ascolese AM, DE Rose F, Bello L, Masci G, Santoro A, Scorsetti M.

Anticancer Res. 2017 Dec;37(12):7057-7062.


On the gEUD biological optimization objective for organs at risk in Photon Optimizer of Eclipse treatment planning system.

Fogliata A, Thompson S, Stravato A, Tomatis S, Scorsetti M, Cozzi L.

J Appl Clin Med Phys. 2018 Jan;19(1):106-114. doi: 10.1002/acm2.12224. Epub 2017 Nov 20.


Are three weeks hypofractionated radiation therapy (HFRT) comparable to six weeks for newly diagnosed glioblastoma patients? Results of a phase II study.

Navarria P, Pessina F, Tomatis S, Soffietti R, Grimaldi M, Lopci E, Chiti A, Leonetti A, Casarotti A, Rossi M, Cozzi L, Ascolese AM, Simonelli M, Marcheselli S, Santoro A, Clerici E, Bello L, Scorsetti M.

Oncotarget. 2017 Jun 28;8(40):67696-67708. doi: 10.18632/oncotarget.18809. eCollection 2017 Sep 15.


Prediction of disease-free survival by the PET/CT radiomic signature in non-small cell lung cancer patients undergoing surgery.

Kirienko M, Cozzi L, Antunovic L, Lozza L, Fogliata A, Voulaz E, Rossi A, Chiti A, Sollini M.

Eur J Nucl Med Mol Imaging. 2018 Feb;45(2):207-217. doi: 10.1007/s00259-017-3837-7. Epub 2017 Sep 24.


Stereotactic/hypofractionated body radiation therapy as an effective treatment for lymph node metastases from colorectal cancer: an institutional retrospective analysis.

Franzese C, Fogliata A, Comito T, Tozzi A, Iftode C, Clerici E, Franceschini D, Navarria P, Ascolese AM, Di Brina L, De Rose F, D'Agostino GR, Cozzi L, Scorsetti M.

Br J Radiol. 2017 Nov;90(1079):20170422. doi: 10.1259/bjr.20170422. Epub 2017 Oct 3.


Establishment and genomic characterization of the new chordoma cell line Chor-IN-1.

Bosotti R, Magnaghi P, Di Bella S, Cozzi L, Cusi C, Bozzi F, Beltrami N, Carapezza G, Ballinari D, Amboldi N, Lupi R, Somaschini A, Raddrizzani L, Salom B, Galvani A, Stacchiotti S, Tamborini E, Isacchi A.

Sci Rep. 2017 Aug 23;7(1):9226. doi: 10.1038/s41598-017-10044-3.


Multi-isocentric 4π volumetric-modulated arc therapy approach for head and neck cancer.

Subramanian VS, Subramani V, Chilukuri S, Kathirvel M, Arun G, Swamy ST, Subramanian K, Fogliata A, Cozzi L.

J Appl Clin Med Phys. 2017 Sep;18(5):293-300. doi: 10.1002/acm2.12164. Epub 2017 Aug 20.


Outcome evaluation of patients with newly diagnosed anaplastic gliomas treated in a single institution.

Pessina F, Navarria P, Cozzi L, Tomatis S, Clerici E, Ascolese AM, Simonelli M, Perrino M, Riva M, Rossi M, Rudà R, Santoro A, Bello L, Scorsetti M.

CNS Oncol. 2017 Jul 18. doi: 10.2217/cns-2016-0043. [Epub ahead of print]


Maximize surgical resection beyond contrast-enhancing boundaries in newly diagnosed glioblastoma multiforme: is it useful and safe? A single institution retrospective experience.

Pessina F, Navarria P, Cozzi L, Ascolese AM, Simonelli M, Santoro A, Clerici E, Rossi M, Scorsetti M, Bello L.

J Neurooncol. 2017 Oct;135(1):129-139. doi: 10.1007/s11060-017-2559-9. Epub 2017 Jul 8.


Outcome Evaluation of Patients with Limited Brain Metastasis From Malignant Melanoma, Treated with Surgery, Radiation Therapy, and Targeted Therapy.

Pessina F, Navarria P, Tomatis S, Cozzi L, Franzese C, Di Guardo L, Ascolese AM, Reggiori G, Franceschini D, Del Vecchio M, Bello L, Scorsetti M.

World Neurosurg. 2017 Sep;105:184-190. doi: 10.1016/j.wneu.2017.05.131. Epub 2017 May 31.


Intercenter validation of a knowledge based model for automated planning of volumetric modulated arc therapy for prostate cancer. The experience of the German RapidPlan Consortium.

Schubert C, Waletzko O, Weiss C, Voelzke D, Toperim S, Roeser A, Puccini S, Piroth M, Mehrens C, Kueter JD, Hierholz K, Gerull K, Fogliata A, Block A, Cozzi L.

PLoS One. 2017 May 22;12(5):e0178034. doi: 10.1371/journal.pone.0178034. eCollection 2017.


Medium-term effect of sublingual l-glutathione supplementation on flow-mediated dilation in subjects with cardiovascular risk factors.

Campolo J, Bernardi S, Cozzi L, Rocchiccioli S, Dellanoce C, Cecchettini A, Tonini A, Parolini M, De Chiara B, Micheloni G, Pelosi G, Passino C, Giannattasio C, Parodi O.

Nutrition. 2017 Jun;38:41-47. doi: 10.1016/j.nut.2016.12.018. Epub 2017 Jan 7.


Occurrence and Trend of Hepatitis A Virus in Bivalve Molluscs Production Areas Following a Contamination Event.

Suffredini E, Proroga YTR, Di Pasquale S, Di Maro O, Losardo M, Cozzi L, Capuano F, De Medici D.

Food Environ Virol. 2017 Dec;9(4):423-433. doi: 10.1007/s12560-017-9302-8. Epub 2017 Apr 27.


RapidPlan head and neck model: the objectives and possible clinical benefit.

Fogliata A, Reggiori G, Stravato A, Lobefalo F, Franzese C, Franceschini D, Tomatis S, Mancosu P, Scorsetti M, Cozzi L.

Radiat Oncol. 2017 Apr 27;12(1):73. doi: 10.1186/s13014-017-0808-x.


Knowledge-based treatment planning: An inter-technique and inter-system feasibility study for prostate cancer.

Cagni E, Botti A, Micera R, Galeandro M, Sghedoni R, Orlandi M, Iotti C, Cozzi L, Iori M.

Phys Med. 2017 Apr;36:38-45. doi: 10.1016/j.ejmp.2017.03.002. Epub 2017 Mar 17.


PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology.

Sollini M, Cozzi L, Antunovic L, Chiti A, Kirienko M.

Sci Rep. 2017 Mar 23;7(1):358. doi: 10.1038/s41598-017-00426-y. Review.


Moderate hypofractionated radiotherapy with volumetric modulated arc therapy and simultaneous integrated boost for pelvic irradiation in prostate cancer.

Franzese C, Fogliata A, D'Agostino GR, Di Brina L, Comito T, Navarria P, Cozzi L, Scorsetti M.

J Cancer Res Clin Oncol. 2017 Jul;143(7):1301-1309. doi: 10.1007/s00432-017-2375-9. Epub 2017 Mar 8.


Role of stereotactic body radiation therapy for lung metastases from radio-resistant primary tumours.

Franceschini D, Cozzi L, De Rose F, Navarria P, Franzese C, Comito T, Iftode C, Tozzi A, Di Brina L, Ascolese AM, Clerici E, D'Agostino G, Fogliata A, Scorsetti M.

J Cancer Res Clin Oncol. 2017 Jul;143(7):1293-1299. doi: 10.1007/s00432-017-2373-y. Epub 2017 Mar 3.


Outcome appraisal of patients with limited brain metastases (BMs) from non small cell lung cancer (NSCLC) treated with different local therapeutic strategies: a single institute evaluation.

Pessina F, Navarria P, Cozzi L, Tomatis S, Ascolese AM, Franzese C, Toschi L, Santoro A, De Rose F, Franceschini D, Bello L, Scorsetti M.

Br J Radiol. 2017 Apr;90(1072):20170022. doi: 10.1259/bjr.20170022. Epub 2017 Mar 3.

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