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Items: 16

1.

A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424.

Woodcock VK, Clive S, Wilson RH, Coyle VM, Stratford MRL, Folkes LK, Eastell R, Barton C, Jones P, Kazmi-Stokes S, Turner H, Halford S, Harris AL, Middleton MR.

Br J Cancer. 2018 Mar 20;118(6):770-776. doi: 10.1038/bjc.2017.484. Epub 2018 Feb 13.

2.

Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival.

Alderdice M, Dunne PD, Cole AJ, O'Reilly PG, McArt DG, Bingham V, Fuchs MA, McQuaid S, Loughrey MB, Murray GI, Samuel LM, Lawler M, Wilson RH, Salto-Tellez M, Coyle VM.

Mod Pathol. 2017 Sep;30(9):1287-1298. doi: 10.1038/modpathol.2017.47. Epub 2017 Jun 16.

3.

Molecular Subtypes and Personalized Therapy in Metastatic Colorectal Cancer.

Graham DM, Coyle VM, Kennedy RD, Wilson RH.

Curr Colorectal Cancer Rep. 2016;12:141-150. Epub 2016 Apr 18. Review.

4.

Immune modulation in advanced radiotherapies: Targeting out-of-field effects.

Hanna GG, Coyle VM, Prise KM.

Cancer Lett. 2015 Nov 28;368(2):246-51. doi: 10.1016/j.canlet.2015.04.007. Epub 2015 Apr 16. Review.

PMID:
25892550
5.

Re: test of four colon cancer risk-scores in formalin fixed paraffin embedded microarray gene expression data.

Graham DM, Turkington RC, Salto-Tellez M, Coyle VM, Wilson RH.

J Natl Cancer Inst. 2015 Mar 10;107(5). pii: djv055. doi: 10.1093/jnci/djv055. No abstract available.

PMID:
25758031
6.

A randomised double-blind placebo-controlled phase II study of AGI004 for control of chemotherapy-induced diarrhoea.

Coyle VM, Lungulescu D, Toganel C, Niculescu A, Pop S, Ciuleanu T, Cebotaru C, Devane J, Martin M, Wilson RH.

Br J Cancer. 2013 Mar 19;108(5):1027-33. doi: 10.1038/bjc.2013.35. Epub 2013 Mar 5.

7.

Metastatic melanoma: a regional review and future directions.

Khan KH, Goody RB, Hameed H, Jalil A, Coyle VM, McAleer JJ.

Tumori. 2012 Sep-Oct;98(5):575-80. doi: 10.1700/1190.13197.

PMID:
23235751
8.

Pharmacogenomic profiling and pathway analyses identify MAPK-dependent migration as an acute response to SN38 in p53 null and p53-mutant colorectal cancer cells.

Allen WL, Turkington RC, Stevenson L, Carson G, Coyle VM, Hector S, Dunne P, Van Schaeybroeck S, Longley DB, Johnston PG.

Mol Cancer Ther. 2012 Aug;11(8):1724-34. doi: 10.1158/1535-7163.MCT-12-0207. Epub 2012 Jun 4.

9.

A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer.

Allen WL, Stevenson L, Coyle VM, Jithesh PV, Proutski I, Carson G, Gordon MA, Lenz HJ, Van Schaeybroeck S, Longley DB, Johnston PG.

Mol Cancer Ther. 2012 Jan;11(1):119-31. doi: 10.1158/1535-7163.MCT-11-0510. Epub 2011 Oct 25.

10.

Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer.

McLornan DP, Barrett HL, Cummins R, McDermott U, McDowell C, Conlon SJ, Coyle VM, Van Schaeybroeck S, Wilson R, Kay EW, Longley DB, Johnston PG.

Clin Cancer Res. 2010 Jul 1;16(13):3442-51. doi: 10.1158/1078-0432.CCR-10-0052. Epub 2010 Jun 22.

11.

Genomic markers for decision making: what is preventing us from using markers?

Coyle VM, Johnston PG.

Nat Rev Clin Oncol. 2010 Feb;7(2):90-7. doi: 10.1038/nrclinonc.2009.214. Epub 2009 Dec 15. Review.

PMID:
20010899
12.

Genomic profiling of colorectal cancer.

Coyle VM, Johnston PG.

Eur J Cancer. 2009 Sep;45 Suppl 1:371-4. doi: 10.1016/S0959-8049(09)70053-X. No abstract available.

PMID:
19775635
13.

Clinical determinants of response to irinotecan-based therapy derived from cell line models.

Allen WL, Coyle VM, Jithesh PV, Proutski I, Stevenson L, Fenning C, Longley DB, Wilson RH, Gordon M, Lenz HJ, Johnston PG.

Clin Cancer Res. 2008 Oct 15;14(20):6647-55. doi: 10.1158/1078-0432.CCR-08-0452.

14.

Predictive and prognostic markers in colorectal cancer.

Turkington RC, Coyle VM, Johnston PG, Eatock MM.

Per Med. 2007 Aug;4(3):295-306. doi: 10.2217/17410541.4.3.295.

PMID:
29788671
15.

Predicting the outcome of chemotherapy for colorectal cancer.

Allen WL, Coyle VM, Johnston PG.

Curr Opin Pharmacol. 2006 Aug;6(4):332-6. Epub 2006 Jun 5. Review.

PMID:
16750422
16.

Catheter-related bloodstream infection in adult haematology patients: catheter removal practice and outcome.

Coyle VM, McMullan R, Morris TC, Rooney PJ, Hedderwick S.

J Hosp Infect. 2004 Aug;57(4):325-31.

PMID:
15262394

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