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Items: 1 to 50 of 74

1.

Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes.

Zhang Z, Amorosa LF, Coyle SM, Macor MA, Birnbaum MJ, Lee LY, Haimovich B.

Diabetes. 2016 Aug;65(8):2224-34. doi: 10.2337/db16-0027. Epub 2016 May 10.

2.

Reverse engineering GTPase programming languages with reconstituted signaling networks.

Coyle SM.

Small GTPases. 2016 Jul 2;7(3):168-72. doi: 10.1080/21541248.2016.1178367. Epub 2016 Apr 29. Review.

3.

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors.

Morsut L, Roybal KT, Xiong X, Gordley RM, Coyle SM, Thomson M, Lim WA.

Cell. 2016 Feb 11;164(4):780-91. doi: 10.1016/j.cell.2016.01.012. Epub 2016 Jan 28.

4.
5.

Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes.

Zhang Z, Amorosa LF, Coyle SM, Macor MA, Lubitz SE, Carson JL, Birnbaum MJ, Lee LY, Haimovich B.

J Immunol. 2015 Sep 1;195(5):2452-60. doi: 10.4049/jimmunol.1500944. Epub 2015 Jul 31.

6.

Human metabolic response to systemic inflammation: assessment of the concordance between experimental endotoxemia and clinical cases of sepsis/SIRS.

Kamisoglu K, Haimovich B, Calvano SE, Coyle SM, Corbett SA, Langley RJ, Kingsmore SF, Androulakis IP.

Crit Care. 2015 Mar 3;19:71. doi: 10.1186/s13054-015-0783-2.

7.

Product binding enforces the genomic specificity of a yeast polycomb repressive complex.

Dumesic PA, Homer CM, Moresco JJ, Pack LR, Shanle EK, Coyle SM, Strahl BD, Fujimori DG, Yates JR 3rd, Madhani HD.

Cell. 2015 Jan 15;160(1-2):204-18. doi: 10.1016/j.cell.2014.11.039. Epub 2014 Dec 18.

8.

Physiologic variability at the verge of systemic inflammation: multiscale entropy of heart rate variability is affected by very low doses of endotoxin.

Herlitz GN, Arlow RL, Cheung NH, Coyle SM, Griffel B, Macor MA, Lowry SF, Calvano SE, Gale SC.

Shock. 2015 Feb;43(2):133-9. doi: 10.1097/SHK.0000000000000276.

9.

Integrated transcriptional and metabolic profiling in human endotoxemia.

Kamisoglu K, Calvano SE, Coyle SM, Corbett SA, Androulakis IP.

Shock. 2014 Dec;42(6):499-508. doi: 10.1097/SHK.0000000000000248.

PMID:
25061728
10.

APOε4 is associated with enhanced in vivo innate immune responses in human subjects.

Gale SC, Gao L, Mikacenic C, Coyle SM, Rafaels N, Murray Dudenkov T, Madenspacher JH, Draper DW, Ge W, Aloor JJ, Azzam KM, Lai L, Blackshear PJ, Calvano SE, Barnes KC, Lowry SF, Corbett S, Wurfel MM, Fessler MB.

J Allergy Clin Immunol. 2014 Jul;134(1):127-34. doi: 10.1016/j.jaci.2014.01.032. Epub 2014 Mar 18.

11.

Natural history of retained surgical items supports the need for team training, early recognition, and prompt retrieval.

Stawicki SP, Cook CH, Anderson HL 3rd, Chowayou L, Cipolla J, Ahmed HM, Coyle SM, Gracias VH, Evans DC, Marchigiani R, Adams RC, Seamon MJ, Martin ND, Steinberg SM, Moffatt-Bruce SD; OPUS 12 Foundation Multicenter Trials Group.

Am J Surg. 2014 Jul;208(1):65-72. doi: 10.1016/j.amjsurg.2013.09.029. Epub 2014 Jan 16.

PMID:
24524864
12.

Effects of coupled dose and rhythm manipulation of plasma cortisol levels on leukocyte transcriptional response to endotoxin challenge in humans.

Kamisoglu K, Sleight K, Nguyen TT, Calvano SE, Coyle SM, Corbett SA, Androulakis IP.

Innate Immun. 2014 Oct;20(7):774-84. doi: 10.1177/1753425913508458. Epub 2013 Nov 11.

PMID:
24217219
13.

Temporal metabolic profiling of plasma during endotoxemia in humans.

Kamisoglu K, Sleight KE, Calvano SE, Coyle SM, Corbett SA, Androulakis IP.

Shock. 2013 Dec;40(6):519-26. doi: 10.1097/SHK.0000000000000063.

14.

Exploitation of latent allostery enables the evolution of new modes of MAP kinase regulation.

Coyle SM, Flores J, Lim WA.

Cell. 2013 Aug 15;154(4):875-87. doi: 10.1016/j.cell.2013.07.019.

15.

Cellular metabolic regulators: novel indicators of low-grade inflammation in humans.

Haimovich B, Zhang Z, Calvano JE, Calvano SE, Kumar A, Macor MA, Corbett S, Coyle SM, Lowry SF.

Ann Surg. 2014 May;259(5):999-1006. doi: 10.1097/SLA.0b013e31829a4352.

16.

Experimental human endotoxemia: a model of the systemic inflammatory response syndrome?

Calvano SE, Coyle SM.

Surg Infect (Larchmt). 2012 Oct;13(5):293-9. doi: 10.1089/sur.2012.155. Epub 2012 Oct 16.

17.

Retained surgical items: a problem yet to be solved.

Stawicki SP, Moffatt-Bruce SD, Ahmed HM, Anderson HL 3rd, Balija TM, Bernescu I, Chan L, Chowayou L, Cipolla J, Coyle SM, Gracias VH, Gunter OL, Marchigiani R, Martin ND, Patel J, Seamon MJ, Vagedes E, Ellison EC, Steinberg SM, Cook CH.

J Am Coll Surg. 2013 Jan;216(1):15-22. doi: 10.1016/j.jamcollsurg.2012.08.026. Epub 2012 Oct 4.

PMID:
23041050
18.

Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation.

Zalatan JG, Coyle SM, Rajan S, Sidhu SS, Lim WA.

Science. 2012 Sep 7;337(6099):1218-22. doi: 10.1126/science.1220683. Epub 2012 Aug 9.

19.

Continuous enteral and parenteral feeding each reduces heart rate variability but differentially influences monocyte gene expression in humans.

Gale SC, Shanker BA, Coyle SM, Macor MA, Choi CW, Calvano SE, Corbett SA, Lowry SF.

Shock. 2012 Aug;38(3):255-61. doi: 10.1097/SHK.0b013e31826171b9.

20.

Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay.

Jinek M, Coyle SM, Doudna JA.

Mol Cell. 2011 Mar 4;41(5):600-8. doi: 10.1016/j.molcel.2011.02.004.

21.

A novel model of common Toll-like receptor 4- and injury-induced transcriptional themes in human leukocytes.

Haimovich B, Reddell MT, Calvano JE, Calvano SE, Macor MA, Coyle SM, Lowry SF.

Crit Care. 2010;14(5):R177. doi: 10.1186/cc9283. Epub 2010 Oct 7.

22.

Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.

Weeks AM, Coyle SM, Jinek M, Doudna JA, Chang MC.

Biochemistry. 2010 Nov 2;49(43):9269-79. doi: 10.1021/bi101102u.

23.

Voluntarily produced increases in heart rate variability modulate autonomic effects of endotoxin induced systemic inflammation: an exploratory study.

Lehrer P, Karavidas MK, Lu SE, Coyle SM, Oikawa LO, Macor M, Calvano SE, Lowry SF.

Appl Psychophysiol Biofeedback. 2010 Dec;35(4):303-15. doi: 10.1007/s10484-010-9139-5.

PMID:
20635134
24.

Coping strategies in a strongly schooling fish, the common carp Cyprinus carpio.

Huntingford FA, Andrew G, Mackenzie S, Morera D, Coyle SM, Pilarczyk M, Kadri S.

J Fish Biol. 2010 May;76(7):1576-91. doi: 10.1111/j.1095-8649.2010.02582.x.

PMID:
20557617
25.

Relationship of basal heart rate variability to in vivo cytokine responses after endotoxin exposure.

Jan BU, Coyle SM, Macor MA, Reddell M, Calvano SE, Lowry SF.

Shock. 2010 Apr;33(4):363-8. doi: 10.1097/SHK.0b013e3181b66bf4.

26.

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.

Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA.

Nat Struct Mol Biol. 2010 Feb;17(2):238-40. doi: 10.1038/nsmb.1768. Epub 2010 Jan 24.

27.

In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes.

Haimovich B, Calvano J, Haimovich AD, Calvano SE, Coyle SM, Lowry SF.

Crit Care Med. 2010 Mar;38(3):751-8. doi: 10.1097/CCM.0b013e3181cd131c.

28.

Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense.

Wiedenheft B, Zhou K, Jinek M, Coyle SM, Ma W, Doudna JA.

Structure. 2009 Jun 10;17(6):904-12. doi: 10.1016/j.str.2009.03.019.

29.

Influence of acute epinephrine infusion on endotoxin-induced parameters of heart rate variability: a randomized controlled trial.

Jan BU, Coyle SM, Oikawa LO, Lu SE, Calvano SE, Lehrer PM, Lowry SF.

Ann Surg. 2009 May;249(5):750-6. doi: 10.1097/SLA.0b013e3181a40193.

30.

Direct link between RACK1 function and localization at the ribosome in vivo.

Coyle SM, Gilbert WV, Doudna JA.

Mol Cell Biol. 2009 Mar;29(6):1626-34. doi: 10.1128/MCB.01718-08. Epub 2008 Dec 29.

31.

A single nucleotide polymorphism in the Mdm2 promoter and risk of sepsis.

Kleiman DA, Calvano JE, Coyle SM, Macor MA, Calvano SE, Lowry SF.

Am J Surg. 2009 Jan;197(1):43-8. doi: 10.1016/j.amjsurg.2007.12.049. Epub 2008 Jun 16.

PMID:
18558393
32.

Low-dose steroid alters in vivo endotoxin-induced systemic inflammation but does not influence autonomic dysfunction.

Alvarez SM, Katsamanis Karavidas M, Coyle SM, Lu SE, Macor M, Oikawa LO, Lehrer PM, Calvano SE, Lowry SF.

J Endotoxin Res. 2007;13(6):358-68. doi: 10.1177/0968051907086465.

PMID:
18182463
33.

Brain-computer interface using a simplified functional near-infrared spectroscopy system.

Coyle SM, Ward TE, Markham CM.

J Neural Eng. 2007 Sep;4(3):219-26. Epub 2007 Apr 27.

PMID:
17873424
34.

Parallel evolution of Pitx1 underlies pelvic reduction in Scottish threespine stickleback (Gasterosteus aculeatus).

Coyle SM, Huntingford FA, Peichel CL.

J Hered. 2007 Sep-Oct;98(6):581-6. Epub 2007 Aug 9.

PMID:
17693397
35.

Nicotine exposure alters in vivo human responses to endotoxin.

Wittebole X, Hahm S, Coyle SM, Kumar A, Calvano SE, Lowry SF.

Clin Exp Immunol. 2007 Jan;147(1):28-34.

36.

Gender influences in vivo human responses to endotoxin.

Coyle SM, Calvano SE, Lowry SF.

Shock. 2006 Dec;26(6):538-43.

PMID:
17117126
37.

Response to systemic endotoxemia among humans bearing polymorphisms of the Toll-like receptor 4 (hTLR4).

Calvano JE, Bowers DJ, Coyle SM, Macor M, Reddell MT, Kumar A, Calvano SE, Lowry SF.

Clin Immunol. 2006 Nov;121(2):186-90. Epub 2006 Jul 7.

PMID:
16829202
38.

Polymorphisms of heat shock protein-70 (HSPA1B and HSPA1L loci) do not influence infection or outcome risk in critically ill surgical patients.

Bowers DJ, Calvano JE, Alvarez SM, Coyle SM, Macor MA, Kumar A, Calvano SE, Lowry SF.

Shock. 2006 Feb;25(2):117-22.

PMID:
16525348
40.

Effects of drotrecogin alfa (activated) in human endotoxemia.

Kalil AC, Coyle SM, Um JY, LaRosa SP, Turlo MA, Calvano SE, Sundin DP, Nelson DR, Lowry SF.

Shock. 2004 Mar;21(3):222-9.

PMID:
14770034
41.
42.

Influence of the TNF-alpha and TNF-beta polymorphisms upon infectious risk and outcome in surgical intensive care patients.

Calvano JE, Um JY, Agnese DM, Hahm SJ, Kumar A, Coyle SM, Calvano SE, Lowry SF.

Surg Infect (Larchmt). 2003 Summer;4(2):163-9.

PMID:
12906716
43.

Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections.

Agnese DM, Calvano JE, Hahm SJ, Coyle SM, Corbett SA, Calvano SE, Lowry SF.

J Infect Dis. 2002 Nov 15;186(10):1522-5. Epub 2002 Oct 29.

PMID:
12404174
44.

Shifts in relative prevalence of laryngeal pathology in a treatment-seeking population.

Coyle SM, Weinrich BD, Stemple JC.

J Voice. 2001 Sep;15(3):424-40.

PMID:
11575638
45.

Approaching the millennium. How can Catholic healthcare best celebrate the "Year of the Lord's Favor"?

Coyle SM.

Health Prog. 1999 Jan-Feb;80(1):24-6, 29. No abstract available.

PMID:
10345102
46.

Neutralization of TNF does not influence endotoxininduced changes in thyroid hormone metabolism in humans.

van der Poll T, Endert E, Coyle SM, Agosti JM, Lowry SF.

Am J Physiol. 1999 Feb;276(2 Pt 2):R357-62.

PMID:
9950912
47.

Multivariate analysis of 9 disease-associated variables for outcome prediction in patients with sepsis.

Calvano SE, Coyle SM, Barbosa KS, Barie PS, Lowry SF.

Arch Surg. 1998 Dec;133(12):1347-50.

PMID:
9865654
48.

The influence of human endotoxemia on CD95-induced apoptosis.

Lin E, Katz JA, Calvano SE, Coyle SM, Randhawa S, Shahin I, Kumar A, Lowry SF.

Arch Surg. 1998 Dec;133(12):1322-7.

PMID:
9865650
49.

Parenteral nutrition facilitates activation of coagulation but not of fibrinolysis during human endotoxemia.

van der Poll T, Levi M, Braxton CC, Coyle SM, Roth M, ten Cate JW, Lowry SF.

J Infect Dis. 1998 Mar;177(3):793-5.

PMID:
9498467
50.

Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans.

van der Poll T, Coyle SM, Levi M, Jansen PM, Dentener M, Barbosa K, Buurman WA, Hack CE, ten Cate JW, Agosti JM, Lowry SF.

Blood. 1997 May 15;89(10):3727-34.

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